LOCUS       NM_153801               2373 bp    mRNA    linear   ROD 11-DEC-2024
DEFINITION  Mus musculus trans-2,3-enoyl-CoA reductase-like (Tecrl), mRNA.
ACCESSION   NM_153801
VERSION     NM_153801.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2373)
  AUTHORS   Geng,S., Liu,S.B., He,W., Pan,X., Sun,Y., Xue,T., Han,S., Lou,J.,
            Chang,Y., Zheng,J., Shi,X., Li,Y. and Song,Y.H.
  TITLE     Deletion of TECRL promotes skeletal muscle repair by up-regulating
            EGR2
  JOURNAL   Proc Natl Acad Sci U S A 121 (21), e2317495121 (2024)
   PUBMED   38753506
  REMARK    GeneRIF: Deletion of TECRL promotes skeletal muscle repair by
            up-regulating EGR2.
REFERENCE   2  (bases 1 to 2373)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 2373)
  AUTHORS   Hou,C., Jiang,X., Zhang,H., Zheng,J., Qiu,Q., Zhang,Y., Sun,X.,
            Xu,M., Chang,A.C.Y., Xie,L. and Xiao,T.
  TITLE     TECRL deficiency results in aberrant mitochondrial function in
            cardiomyocytes
  JOURNAL   Commun Biol 5 (1), 470 (2022)
   PUBMED   35577932
  REMARK    GeneRIF: TECRL deficiency results in aberrant mitochondrial
            function in cardiomyocytes.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2373)
  AUTHORS   Pang,A.L., Taylor,H.C., Johnson,W., Alexander,S., Chen,Y., Su,Y.A.,
            Li,X., Ravindranath,N., Dym,M., Rennert,O.M. and Chan,W.Y.
  TITLE     Identification of differentially expressed genes in mouse
            spermatogenesis
  JOURNAL   J Androl 24 (6), 899-911 (2003)
   PUBMED   14581517
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK052284.1, AK052378.1 and CJ066147.1.
            
            On Jul 21, 2009 this sequence version replaced NM_153801.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF548365.1, AK052284.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849383 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1852              AK052284.1         4-1855
            1853-2350           AK052378.1         1616-2113
            2351-2373           CJ066147.1         306-328
FEATURES             Location/Qualifiers
     source          1..2373
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 43.0 cM"
     gene            1..2373
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
                     /note="trans-2,3-enoyl-CoA reductase-like"
                     /db_xref="GeneID:243078"
                     /db_xref="MGI:MGI:2444966"
     exon            1..423
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
                     /inference="alignment:Splign:2.1.0"
     CDS             196..1281
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
                     /note="steroid 5 alpha-reductase 2-like 2; synaptic
                     glycoprotein SC2-like; steroid 5-alpha-reductase 2-like 2
                     protein"
                     /codon_start=1
                     /product="trans-2,3-enoyl-CoA reductase-like"
                     /protein_id="NP_722496.2"
                     /db_xref="CCDS:CCDS19375.1"
                     /db_xref="GeneID:243078"
                     /db_xref="MGI:MGI:2444966"
                     /translation="MFKRHKSLERKRELLFQGLPQSTMKNNARNFHSLSQLVLSAGPL
                     KTTTAVKHSKTTHFEIEILDAHTRKQICIVDKVTQTSTIHDVKQKFHKACPKWYPSRI
                     GLQLEYGGPYLRDYITVQSVAASSIITLYFTDLGQQVGWTTVFLAEYSGPLLIYLLFY
                     LRSSYIYDVKESTRWPRHPVVHLAFFCHCIHYIRLLLETLFVHKVSTGHSPMKNLIKG
                     CAFYWGFTSWMAYYINHPRYTPPSFGNRQVIVSAINFLFCEAGNHFINTVLAHPNHTG
                     SNACFPSPNYNPFTWLFFLVSCPNYTYEIGSWISFTVMTQTLPVGIFTILMTIQMSLW
                     ARKKHKIYRKKFNSYVHRKSAIIPLIL"
     exon            424..475
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            476..520
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            521..624
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            625..740
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            741..846
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            847..919
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            920..963
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            964..1021
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..1107
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1108..1153
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1154..2373
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1832..1837
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
                     /note="hexamer: AATAAA"
     polyA_site      1857
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
                     /note="major polyA site"
     regulatory      2022..2027
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
                     /note="hexamer: ATTAAA"
     polyA_site      2042
                     /gene="Tecrl"
                     /gene_synonym="D330017N19Rik; Srd5a2l2"
ORIGIN      
        1 gcagcagttc tcaatagtgt tatatataga aatcagatcg gtcattgttt cccagcctgc
       61 taaataaaac tagaccgctg gaatggcatg ccacttgacc tccagggcgt ccacagcagt
      121 gtttaacagg cacaaaggga gtactcttgc aagtatctcc tgtttacatg ccagattccc
      181 ctgctagttc acacaatgtt caaaaggcac aagtccctgg aacgcaagag ggaattgtta
      241 ttccagggac tgccacagtc cacaatgaag aataatgcga gaaatttcca ctctttgtca
      301 caacttgtac tctcagcagg cccgctcaaa actactacag cagtcaaaca ttcaaaaacg
      361 actcactttg agatcgaaat actggatgct catacaagaa aacaaatatg tattgtggat
      421 aaggtcacac aaacatcaac tattcatgat gtcaaacaga agtttcacaa agcatgtcca
      481 aagtggtacc cttctcgaat tggcctacaa ctagaatatg gtggcccata tttgagggac
      541 tacatcacag ttcaaagtgt tgcagcttct tcaattatca cactctattt tacagacttg
      601 ggtcagcaag tcgggtggac tacagtcttt ttggctgaat actcaggacc tctgttaata
      661 taccttcttt tttacttgag gagctcatac atatatgatg tcaaggagag cactagatgg
      721 ccccggcacc ctgtggtaca cttggctttc ttctgccatt gtatccacta catccgactc
      781 ctcctggaga ctttatttgt tcacaaagtt tctacaggac acagtcctat gaaaaacttg
      841 ataaagggtt gtgcatttta ttggggattc acttcttgga tggcttatta tattaatcac
      901 ccaagatata caccaccatc atttggaaac aggcaagtaa tagtgtctgc tatcaacttt
      961 ctgttttgtg aagctggaaa tcatttcatc aatacagttt tggctcatcc aaatcacaca
     1021 ggtagcaatg cctgtttccc aagtccaaat tacaacccct ttacatggtt gtttttcctg
     1081 gtttcctgtc ctaactatac ctatgagatc ggatcttgga ttagtttcac agttatgacc
     1141 cagacacttc cagttggtat tttcacaatc ttaatgacca tccagatgtc tctgtgggca
     1201 cgaaagaagc ataaaatata tcggaagaag ttcaactcat atgttcatag gaaatcagcc
     1261 ataattccac tcatattata agtaaatata gctattctaa tctgagcaag aagtgcagaa
     1321 tataaattca ctcaaaaagg cttaggaagt gattacctat tataatgcaa caattttatt
     1381 ctaaatattc ctctccaaac tctcctgtct atacccacaa ctctttgcct attctttccc
     1441 tcacccttct ctcagcattg tgatctgctg acttgtgggt tttgcctcat ctctgtgagc
     1501 tcacattatc agcccgatga gtttgaagac accgtttcct tggagttctc tatcatttct
     1561 gggctcttac aatctttcca tctcctcatt agcatagatg tctaagtctt aaggaagggg
     1621 gtttatttaa gttacagctt atatctatat taaaatgctg tctctaaaat gtaagccaag
     1681 ttacaaaatt cctgattttg tttgtgtgtt gacatttgcc aggaatggat caaaaattta
     1741 agatgtttca gcccaaatta taattattgg tctcagttca ggtcaaaatt cagctattgg
     1801 tgtatttcaa ttataccaag tttgctcctg aaataaaaat tttccttgaa ttaataataa
     1861 tgattcttct atttatattg tttacaacat aaaagtataa aataatcctc tggttttctc
     1921 aatatattca aagagaatat agcttaatgt tgctgtatag gttcaattaa agttactctt
     1981 gtaccttaga tgacttgtac catctgtgta taacaataat aattaaaaat tcagtttcta
     2041 aaggctgttt aaaagttaat ttatgccctg attcatatag aactttataa ttactgttgg
     2101 tttcaaggag cctcagtata gaaagtccca aagacagtat ttcttgctaa caggcccact
     2161 ttatttttga aatacttttc agtgatgatg catgaaaact gcaaaatgat acttggaatt
     2221 atttacaaaa tcaatgtaca agtaacttag aatgactttt gccagaaaaa aaaaagaatt
     2281 tctattcttg aatttaacaa gaaacaaaga cctgtaatat ggtgccaaaa taaagtaaaa
     2341 tttgtataat atattaaaag gaatcaagat aat
//
