LOCUS       NM_027410               5123 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus tectonin beta-propeller repeat containing 1 (Tecpr1),
            transcript variant 1, mRNA.
ACCESSION   NM_027410 XM_149712 XM_899644 XM_899648 XM_899658 XM_899672
            XM_925605 XM_925606 XM_925608 XM_925610 XM_925611 XM_983148
VERSION     NM_027410.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5123)
  AUTHORS   Kim,J.H., Hong,S.B., Lee,J.K., Han,S., Roh,K.H., Lee,K.E.,
            Kim,Y.K., Choi,E.J. and Song,H.K.
  TITLE     Insights into autophagosome maturation revealed by the structures
            of ATG5 with its interacting partners
  JOURNAL   Autophagy 11 (1), 75-87 (2015)
   PUBMED   25484072
REFERENCE   2  (bases 1 to 5123)
  AUTHORS   Ogawa,M., Yoshikawa,Y., Kobayashi,T., Mimuro,H., Fukumatsu,M.,
            Kiga,K., Piao,Z., Ashida,H., Yoshida,M., Kakuta,S., Koyama,T.,
            Goto,Y., Nagatake,T., Nagai,S., Kiyono,H., Kawalec,M.,
            Reichhart,J.M. and Sasakawa,C.
  TITLE     A Tecpr1-dependent selective autophagy pathway targets bacterial
            pathogens
  JOURNAL   Cell Host Microbe 9 (5), 376-389 (2011)
   PUBMED   21575909
  REMARK    GeneRIF: Although Tecpr1-deficient mice appear normal,
            Tecpr1-deficient mouse embryo fibroblasts were defective for
            selective autophagy and supported increased intracellular
            multiplication of Shigella.
REFERENCE   3  (bases 1 to 5123)
  AUTHORS   Visel,A., Carson,J., Oldekamp,J., Warnecke,M., Jakubcakova,V.,
            Zhou,X., Shaw,C.A., Alvarez-Bolado,G. and Eichele,G.
  TITLE     Regulatory pathway analysis by high-throughput in situ
            hybridization
  JOURNAL   PLoS Genet 3 (10), 1867-1883 (2007)
   PUBMED   17953485
REFERENCE   4  (bases 1 to 5123)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Hara,Y., Nagase,T.,
            Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: I. The complete nucleotide sequences of 100 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 9 (5), 179-188 (2002)
   PUBMED   12465718
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC139636.12, BC046968.1, AK040462.1 and AW048569.1.
            
            On Oct 14, 2017 this sequence version replaced NM_027410.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC046968.1, AK169888.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-37                AC139636.12        142191-142227
            38-4226             BC046968.1         1-4189
            4227-5100           AK040462.1         197-1070
            5101-5123           AW048569.1         1-23                c
FEATURES             Location/Qualifiers
     source          1..5123
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 83.07 cM"
     gene            1..5123
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /note="tectonin beta-propeller repeat containing 1"
                     /db_xref="GeneID:70381"
                     /db_xref="MGI:MGI:1917631"
     exon            1..121
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            122..356
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     CDS             132..3632
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /note="isoform 1 is encoded by transcript variant 1;
                     tectonin beta-propeller repeat-containing protein 1"
                     /codon_start=1
                     /product="tectonin beta-propeller repeat-containing
                     protein 1 isoform 1"
                     /protein_id="NP_081686.1"
                     /db_xref="CCDS:CCDS39377.1"
                     /db_xref="GeneID:70381"
                     /db_xref="MGI:MGI:1917631"
                     /translation="MPTSVLWAVDLFGRVYTLSTAGQYWELCKDVQLEFKRVSAATQC
                     CWGIAGDNQVYLYVCSSDVPIRHREEAYENQRWNPMGGFCEKLLPSDRWPWSDVSGLQ
                     HRPLDGVALPSPHWEWESDWYVDENFGGEPTEKGGWTYAMDFPATYTRDKKWNSCVRR
                     RKWIRYRRYKSRDSWAKIPSKDDPKELPDPFNDLSVGGWEITEEPVGRLSVWAVSLQG
                     KVWYREDVSHPNPEGSSWSLVETPGEVVQISCGPHDLIWATLWEGQALVREGVCRNNP
                     KGSYWSMVEPPGSENGIMHVSAGVSVVWAITKDRKVWFRRGVNSHNPCGTSWIEMVGE
                     MTMVNVGLNDQVWGISCEDRAVYFRQGVTPSELSGKTWKAIVVGRESDRSHSGSSSSL
                     LSAGCFFGDEVRGSGTESAPSDTDASLEVERQGPEQPLPKEALDNSTNLKGSLSKGHE
                     TSGNTDHSTENACLTEGKEKAPETSRSDECRGPASTPAELPWTNIDLKEPKKVSNQPA
                     AGFPETAGLSSLGLFPMGMEEPYGADDHPLWAWVSGGACAVEAGSTLKWFTIQSGLSP
                     SVQTLSLSITPAQTAAWRKQIFQQLTERTKRELESFRHYEQAVEQSVWVKTGALQWWC
                     DWKPHKWVDVRVALEQFTGHDGARDSILFIYYVVHEEKKYLHVFLNEVTVLVPVLNEA
                     KHSFALYTPERTRQRWPVRLAAATEQDMNDWLALLSLSCCESRKVHGRPSPQAIWSVT
                     CKGDIFVSEPSPDLEARERLLPCDQMFWRQMGGHLRIIEANSRGVVWGIGYDHTAWVY
                     TGGYGGGCFQGLASSTSNIYTQSDVKSVYIYENQRWNPVTGYTSRGLPTDRFMWSDVT
                     GLQECTKAGTKPPSLQWTWVSDWYVDFSVPGGTDQEGWQYASDFPASYHGYKTMKDFV
                     RRRCWARKCKLVTSGPWLEVAPITLSDVSIIPESAHADGRGHNVALWAVSDKGDVLCR
                     LGVSELNPAGSSWLHVGTDQPFASVSIGACYQVWAVARDGSAFYRGSVSPSQPAGDCW
                     YHIPSPPKQKLTQVSVGQTSVYALDENGNLWYRAGITPSYPQGSSWEHVSNNVRKVSV
                     GPLDQVWVIANKVQGSHGLSRGTVCRRMGVQPREPKGQGWDYGIGGGWDHISVRANAT
                     RVPRNMSRDREARGPGPVCC"
     exon            357..539
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            540..662
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            663..788
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            789..963
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            964..1064
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            1065..1166
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            1167..1312
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            1313..1818
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            1819..1964
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            1965..2120
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            2121..2270
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            2271..2428
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            2429..2556
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            2557..2659
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            2660..2756
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            2757..2836
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            2837..2893
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            2894..3074
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            3075..3210
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            3211..3303
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            3304..3410
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            3411..3530
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     exon            3531..5106
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5085..5090
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /note="hexamer: AATAAA"
     polyA_site      5103
                     /gene="Tecpr1"
                     /gene_synonym="2210010N04Rik; mKIAA1358"
                     /note="major polyA site"
ORIGIN      
        1 gagttgatta ttgcttccgg cccgccctct agcctgaggc cgggggaggg ccggactgta
       61 gctaaaaccg aggagtacag aagcctccgc tgggaacccg ccccaccggg cgtgggcaca
      121 gcactgcggc catgcccacc tccgtgctgt gggcggtgga cctctttggg agagtgtata
      181 ccctgtccac ggccggtcag tactgggagc tttgcaagga tgtccaattg gagttcaaga
      241 gggtcagtgc ggccacccag tgctgctggg gcatcgccgg cgacaaccag gtctacttgt
      301 atgtgtgctc cagtgatgta cccatccgcc atcgagagga ggcctatgag aatcagcgtt
      361 ggaaccccat gggaggcttc tgtgagaagc tcctgccgag cgaccgctgg ccatggagtg
      421 acgtgagtgg gctccagcat cggccgctgg atggggtagc actgccttcg ccacactggg
      481 aatgggagtc agactggtac gtggatgaga attttggagg ggagcccacc gagaaagggg
      541 ggtggacata cgctatggac tttcctgcca cctacactag agacaagaaa tggaattcat
      601 gtgtgcgaag gaggaaatgg atccggtata ggcgatacaa atcccgggac tcctgggcca
      661 agatcccctc aaaggatgac cccaaggaac tccctgatcc cttcaatgac ctgtctgttg
      721 gggggtggga gatcacagag gaaccagtcg gccgcctgtc agtgtgggct gtatccctgc
      781 agggaaaggt gtggtaccga gaggatgtca gccaccccaa cccagaaggc tcctcctggt
      841 ctctcgtgga aaccccaggg gaggtggtcc agatcagctg tgggccccac gaccttatat
      901 gggccaccct ctgggaggga caggctctgg tcagagaagg agtctgcagg aacaacccaa
      961 aaggaagtta ctggtccatg gtggagcctc ctggatctga aaacggtatc atgcacgtct
     1021 ccgcgggcgt cagtgtggtc tgggccatca cgaaggaccg caaagtgtgg ttccggaggg
     1081 gtgtcaactc tcacaacccc tgtggcacca gctggatcga gatggtcgga gagatgacca
     1141 tggtgaacgt ggggctgaat gaccaggtct ggggtatcag ctgtgaggac cgagccgtat
     1201 acttccggca gggtgtgact cccagcgagc tcagcgggaa gacatggaag gccattgtcg
     1261 tgggccgaga aagtgaccgg tcacactctg gcagctcgtc cagtctcctc agtgctggct
     1321 gcttcttcgg cgacgaggtg aggggcagtg gtacagagtc ggcacccagt gataccgatg
     1381 cctccttgga agttgagaga cagggccccg aacagcctct ccccaaagaa gctttggaca
     1441 attccacaaa ccttaaaggg agcttgtcca agggccacga gaccagcggg aacactgatc
     1501 actccacgga gaacgcctgc ctgactgaag gcaaagaaaa ggctcctgag acctctcgtt
     1561 ctgatgaatg ccgcggccct gcctccacgc cagctgagct gccctggacc aacattgacc
     1621 taaaggagcc caagaaggtg tctaaccagc cagctgctgg ctttcccgag acggcgggcc
     1681 tctcctccct ggggctcttc ccgatgggca tggaggagcc gtacggggca gatgatcatc
     1741 ctctgtgggc ctgggtgtct ggaggcgcat gtgcagtgga ggcgggctct acacttaagt
     1801 ggttcaccat ccagtcaggc ctgtcccctt cagtgcagac gctgtccctg tccatcaccc
     1861 ctgcccagac ggctgcctgg aggaagcaga tcttccagca actcacagaa aggaccaagc
     1921 gggagctgga gagcttcagg cactacgagc aggccgtgga gcagtcagtg tgggtgaaga
     1981 cgggggccct gcagtggtgg tgtgactgga agccccacaa gtgggtggac gtccgtgtgg
     2041 ccctggagca gttcacaggg cacgacgggg ctcgagacag catcctcttc atctattatg
     2101 tggtccatga ggagaagaag tacctacacg tgttcctgaa tgaggtgacc gtgctggtcc
     2161 ctgtgcttaa tgaggccaag cactcctttg ccctctacac ccccgagagg acgagacaga
     2221 ggtggcccgt acgcctggct gccgccacag agcaagacat gaatgactgg ctcgccctgc
     2281 ttagcctgtc ctgctgcgag agccggaagg tccatggacg cccatccccg caggccatct
     2341 ggtctgtcac ttgcaagggt gacatctttg tgagcgagcc cagcccagac ctggaagccc
     2401 gtgagcgcct gctgccctgc gaccagatgt tctggcgaca gatgggaggc cacttgcgga
     2461 tcatagaggc caacagccga ggcgtggtat ggggcattgg ctatgatcac acggcctggg
     2521 tgtacacggg cggctatggc ggcggttgct tccaaggcct ggccagtagc accagcaaca
     2581 tttacacaca gtcagatgtg aagagtgtct acatctatga gaaccagcgt tggaaccctg
     2641 tcacgggcta taccagcagg ggtctgccca ctgaccggtt catgtggagt gatgtcacgg
     2701 gactacaaga atgtaccaag gccggcacaa aacccccatc gctgcagtgg acttgggtct
     2761 ctgactggta tgtggatttc agtgtccccg gaggcaccga tcaggaagga tggcagtatg
     2821 ccagcgattt ccccgcctct taccatgggt acaaaaccat gaaggatttt gtcaggagaa
     2881 ggtgctgggc cagaaaatgc aagctggtga ccagtgggcc gtggctggag gtggccccca
     2941 tcaccctcag cgacgtgtcc atcatcccag agagtgcaca tgctgacggg agagggcaca
     3001 atgttgcact atgggccgtc agtgacaagg gggacgtcct gtgccgcctg ggtgtgtctg
     3061 aactcaaccc cgcgggctcc tcctggctgc atgttggcac tgaccagccc ttcgcctctg
     3121 tctccatcgg agcctgctat caggtgtggg ctgtggccag ggatggctct gcattctacc
     3181 ggggctccgt gtctccctcc cagccagctg gtgactgctg gtaccacatc ccctcccctc
     3241 ccaagcagaa gctgacacag gtgtctgtgg gccagacatc cgtttatgcc ttggacgaaa
     3301 atgggaacct gtggtaccga gcagggatca cccccagcta cccgcagggc tccagctggg
     3361 agcatgtatc caacaatgta cgcaaagtgt ctgtgggacc cctggaccag gtctgggtga
     3421 ttgccaacaa agtccagggg agccatggcc tgagccgggg gacggtgtgt cgtcgcatgg
     3481 gtgtccagcc tcgggagccc aagggacagg gctgggacta tggcattggc ggaggctggg
     3541 accacatctc tgtccgggcc aatgccacca gggtcccaag gaacatgtcc agggatcggg
     3601 aggcccgcgg tccaggtcct gtttgctgct gaggccactc ctcacctgga ggcaaggatg
     3661 gtctgagcct gcagaaccag aactgaaatc tttcttgtgc tgtatgggag ggcatcaccc
     3721 agggccccac acccaaggag tcaggtcaga gtcagccatt tctgcagcac tggcaaaatg
     3781 ccagaggtgt gaaactgcgg ggggccgctc ccactcatgt tctgagtctg tgagggatgc
     3841 tgcggggaag agccgtggta actactgtct gggtccctca gccccggtcc ctgcctgcaa
     3901 tacctcccat ctttccaggc caggaactca gagccctcca tacattctgg ccctagagag
     3961 gcagaggcag ggaggaccct tccacaccta gagaccccaa atcacctcta ggaaaaataa
     4021 cagtggggtt caggtctcca ggcatcagtc gggtcactcc tcagcaggtt ttccaaatgg
     4081 agttttgctt caaaagttaa gcaaagggct ggatgcccat aggccctgca ctcaggaaac
     4141 tgaggcagga ggatcgtgag tttgagacta cccaggacta cataccaaga ctgtcacaaa
     4201 aaaaaaaaaa aaaaaaaaaa aaaaaagaaa atctagataa atacgccagg cacgccatgt
     4261 ctgtactctg aaggtgaagg caagatcagg aattcaaggg tatcctcagg ctccataata
     4321 agtttgaggc cagcctggac tacataagac cccgcctcaa tctaccaaga tgggtacagg
     4381 tcttatcctg gaggtttggg gctccctccc gtggtgcact ggaaggtagt tcccttgtga
     4441 agagtcagca ttatgaactc cagtgtcgtc cctccttcag gaagggggca gggtctgctt
     4501 gcacaggact gtgttgcagg actgtgttgc aggatggcca ggtctgggtg gaggcagcct
     4561 gcactttgga tttgaaggaa gaaatctgtg tcctgtggag agggactggc ccatggcaaa
     4621 tgtgtgcccc agcaggtgat gcctcgtgct tcaggagggc cagagccaag cccgactcta
     4681 cttatttaga gacaggacag agccctaact ggtttgtccc agaatcctcc ccgtttgatg
     4741 tcctggacag gaggggtatc cccagaagct aagaggacac tactctgggg tcccatccca
     4801 aggacatgag tggctccatg tcctccgaat ttccagaggt gagagcagac acacccacgt
     4861 gcagagaggc atcaaggggt tgccctcatg tcagtgtcag ggtcccaagg gggcatctgg
     4921 gtctgtcccc agcggccgtg acctctgtgt tcttctgcac atgtttctca gctgagcacc
     4981 gccagggtgt caccagggtg acgtaccctc tcactgctga gcaccaacaa cagttcactc
     5041 catcagtggc accaaactgt ctacactccc cagatgttct atttaataaa aatttatacc
     5101 acagcgaaaa aaaaaaaaaa aaa
//
