LOCUS       NM_001399994            2058 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus t-complex protein 11 (Tcp11), transcript variant 6,
            mRNA.
ACCESSION   NM_001399994
VERSION     NM_001399994.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2058)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2058)
  AUTHORS   Castaneda,J.M., Miyata,H., Archambeault,D.R., Satouh,Y., Yu,Z.,
            Ikawa,M. and Matzuk,M.M.
  TITLE     Mouse t-complex protein 11 is important for progressive motility in
            spermdagger
  JOURNAL   Biol Reprod 102 (4), 852-862 (2020)
   PUBMED   31837139
  REMARK    GeneRIF: Mouse t-complex protein 11 is important for progressive
            motility in spermdagger.
REFERENCE   3  (bases 1 to 2058)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2058)
  AUTHORS   Stanger,S.J., Law,E.A., Jamsai,D., O'Bryan,M.K., Nixon,B.,
            McLaughlin,E.A., Aitken,R.J. and Roman,S.D.
  TITLE     A novel germ cell protein, SPIF (sperm PKA interacting factor), is
            essential for the formation of a PKA/TCP11 complex that undergoes
            conformational and phosphorylation changes upon capacitation
  JOURNAL   FASEB J 30 (8), 2777-2791 (2016)
   PUBMED   27105888
REFERENCE   5  (bases 1 to 2058)
  AUTHORS   Inagawa,M., Nakajima,K., Makino,T., Ogawa,S., Kojima,M., Ito,S.,
            Ikenishi,A., Hayashi,T., Schwartz,R.J., Nakamura,K., Obayashi,T.,
            Tachibana,M., Shinkai,Y., Maeda,K., Miyagawa-Tomita,S. and
            Takeuchi,T.
  TITLE     Histone H3 lysine 9 methyltransferases, G9a and GLP are essential
            for cardiac morphogenesis
  JOURNAL   Mech Dev 130 (11-12), 519-531 (2013)
   PUBMED   23892084
REFERENCE   6  (bases 1 to 2058)
  AUTHORS   Fraser,L.R.
  TITLE     The modulation of sperm function by fertilization promoting peptide
  JOURNAL   Hum Reprod 13 Suppl 4, 1-10 (1998)
   PUBMED   10091053
  REMARK    Review article
REFERENCE   7  (bases 1 to 2058)
  AUTHORS   Adeoya-Osiguwa,S.A., Dudley,R.K., Hosseini,R. and Fraser,L.R.
  TITLE     FPP modulates mammalian sperm function via TCP-11 and the adenylyl
            cyclase/cAMP pathway
  JOURNAL   Mol Reprod Dev 51 (4), 468-476 (1998)
   PUBMED   9820206
REFERENCE   8  (bases 1 to 2058)
  AUTHORS   Fraser,L.R., Hosseini,R., Hanyalogou,A., Talmor,A. and Dudley,R.K.
  TITLE     TCP-11, the product of a mouse t-complex gene, plays a role in
            stimulation of capacitation and inhibition of the spontaneous
            acrosome reaction
  JOURNAL   Mol Reprod Dev 48 (3), 375-382 (1997)
   PUBMED   9322250
REFERENCE   9  (bases 1 to 2058)
  AUTHORS   Hosseini,R., Ruddy,S., Bains,S., Hynes,G., Marsh,P., Pizzey,J. and
            Dudley,K.
  TITLE     The mouse t-complex gene, Tcp-11, is under translational control
  JOURNAL   Mech Dev 47 (1), 73-80 (1994)
   PUBMED   7947323
REFERENCE   10 (bases 1 to 2058)
  AUTHORS   Mazarakis,N.D., Nelki,D., Lyon,M.F., Ruddy,S., Evans,E.P.,
            Freemont,P. and Dudley,K.
  TITLE     Isolation and characterisation of a testis-expressed
            developmentally regulated gene from the distal inversion of the
            mouse t-complex
  JOURNAL   Development 111 (2), 561-571 (1991)
   PUBMED   1893875
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132460.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: BC058793.1, SRR5189685.158415.1
                                    [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-143               AC132460.3         33241-33383
            144-527             AC132460.3         33545-33928
            528-600             AC132460.3         35792-35864
            601-721             AC132460.3         39078-39198
            722-942             AC132460.3         42019-42239
            943-1079            AC132460.3         43291-43427
            1080-1294           AC132460.3         44178-44392
            1295-1476           AC132460.3         44486-44667
            1477-1640           AC132460.3         45897-46060
            1641-2058           AC132460.3         46682-47099
FEATURES             Location/Qualifiers
     source          1..2058
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 14.62 cM"
     gene            1..2058
                     /gene="Tcp11"
                     /gene_synonym="D17Ken1; Tcp-11"
                     /note="t-complex protein 11"
                     /db_xref="GeneID:21463"
                     /db_xref="MGI:MGI:98544"
     exon            1..143
                     /gene="Tcp11"
                     /gene_synonym="D17Ken1; Tcp-11"
                     /inference="alignment:Splign:2.1.0"
     exon            144..527
                     /gene="Tcp11"
                     /gene_synonym="D17Ken1; Tcp-11"
                     /inference="alignment:Splign:2.1.0"
     exon            528..600
                     /gene="Tcp11"
                     /gene_synonym="D17Ken1; Tcp-11"
                     /inference="alignment:Splign:2.1.0"
     exon            601..721
                     /gene="Tcp11"
                     /gene_synonym="D17Ken1; Tcp-11"
                     /inference="alignment:Splign:2.1.0"
     exon            722..942
                     /gene="Tcp11"
                     /gene_synonym="D17Ken1; Tcp-11"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1079
                     /gene="Tcp11"
                     /gene_synonym="D17Ken1; Tcp-11"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1294
                     /gene="Tcp11"
                     /gene_synonym="D17Ken1; Tcp-11"
                     /inference="alignment:Splign:2.1.0"
     exon            1295..1476
                     /gene="Tcp11"
                     /gene_synonym="D17Ken1; Tcp-11"
                     /inference="alignment:Splign:2.1.0"
     exon            1477..1640
                     /gene="Tcp11"
                     /gene_synonym="D17Ken1; Tcp-11"
                     /inference="alignment:Splign:2.1.0"
     exon            1641..2058
                     /gene="Tcp11"
                     /gene_synonym="D17Ken1; Tcp-11"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2040..2045
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tcp11"
                     /gene_synonym="D17Ken1; Tcp-11"
                     /note="hexamer: AATAAA"
     polyA_site      2058
                     /gene="Tcp11"
                     /gene_synonym="D17Ken1; Tcp-11"
                     /note="major polyA site"
ORIGIN      
        1 agccagccag agcgggcggg ccggcagaga aggaagtgag ctgagtggag agagggaagg
       61 ggagggagaa agtggagggg gagggcggag gtgagccacg gaggggaagg gatgaaagag
      121 gggaagggag aggggaagag gagataccac caccaccacc atcaccagga tgccagacgt
      181 gaaagagagg gcggcccgga aggagcccgg cgcggcagag agcgcctccc gtgaatcccg
      241 cgggggaaac acccgggaga gcgcgagcag cgcccagggg caccgatcgt gtaggttcaa
      301 ccgtcgcccg agcacggccg ccctcacccc agggtccgcg caggggcgcg gggtaaagac
      361 ggcgccacga ggtcccgtgg gccacggagg actgcggact ggcccgacct cccggtgtcc
      421 ccagccctcc gcccgagcga agctcccctc ggtcacgcgt ggggcaccgc ttccgccatc
      481 cccgggaaag ggccacctcg gcgggacccc gagctcgcac aggctaggta tgacggagag
      541 agtccatgac gcttccaagc ttgattgtca gttggaagaa aggagtttat cttcaagcag
      601 cctgaaaggc aaggtcaagg acaccatgcc cagcgacttc tgggagcatc tgaatgagca
      661 gctgtcagcc gtgccccccg acttcagctg tgctcttgag cttctgaagg agatcaaaga
      721 gatcctgttg tccctgctgc tgccacggca gagccgcctg aagaatgaga tcgaggaagc
      781 tctggacatg gagttcctcc agcagcaagc cgaccgcgga gacctgaatg tctcctacct
      841 ctccaagtat atcctcaaca tgatggtctt gttgtgtgcg ccaatccgag acgaggctgt
      901 gcagagactt gagaacattt cagatccggt ccggctgctg agggggatct tccaggtctt
      961 gggacagatg aaaatggaca tggtgaacta caccatccag agcctccagc cccagcttca
     1021 ggaacactcc gtccagtttg agcgggctca gttccaggag cgcctcaaca aagagcccag
     1081 actcctcaac cacaccacga agtggctcac ccaggcggcc acacagctca ttgccccctc
     1141 tgccagttcc tctgacttgc aggactgctc cagctcggcc ggcccatctc ccagtgatgt
     1201 cgccgtccca gagccactca gccccgcgat ggtgctgtct caaggattcc tgaaccttct
     1261 cacctgggac cctgagaatg aagagtttcc tgaaacccta gtggcagaca gaccccggct
     1321 gcaggagctg gagtcgcagc agagtcagct aaccatcctt gcctctgtct tgctggtggc
     1381 cagtagcttc tctgacagtg gtctgtttag ctcaccccag tttgtagaca agctgaaaca
     1441 aatcacgaag tccctggtgg aggatttcaa ctccaggccc gaggaagtga tgcagtcagt
     1501 gagtgagcag gtggtggagg aagtccacca gggtctcgag agcatggggt tggccgctct
     1561 gagcagcgag aatacggcgt ccctggtggg ccagctccag aacattgcca agaaggaaaa
     1621 ctgcgtccgc agcgtcattg accagcgtat acacttgttc ctcaagtgct gctttgtcct
     1681 gggtgtgcag cgatccctct tggaccttcc cgggggcctc actctgatcg aagctgagct
     1741 ggcggaactg ggccagaagt ttgtcagcct gacccatcac aaccagcagg tgtttgcccc
     1801 gtattacacc gagatcttaa aaaccctcat ctccccagcc cagaccctgg ccaccaaagg
     1861 tgggtctctc tgatgacatc ggctcggagc actggcacct tggacccagg agaaagcgca
     1921 tctccctggg atgacatcac cactgagcag cagggtcccc tctgccccac cccccacagc
     1981 cagcacacca gggctgtaac aagacaaaca tgtcaacaac tggcccaaac ccgctccata
     2041 ataaacttgt gaactgca
//
