LOCUS       NM_001360335            2267 bp    mRNA    linear   ROD 31-OCT-2023
DEFINITION  Mus musculus transcription factor-like 5 (basic helix-loop-helix)
            (Tcfl5), transcript variant 1, mRNA.
ACCESSION   NM_001360335 XM_006500652
VERSION     NM_001360335.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2267)
  AUTHORS   Zhang FL, Feng YQ, Wang JY, Zhu KX, Wang L, Yan JM, Li XX, Wang JJ,
            Ge W, De Felici M and Shen W.
  TITLE     Single cell epigenomic and transcriptomic analysis uncovers
            potential transcription factors regulating mitotic/meiotic switch
  JOURNAL   Cell Death Dis 14 (2), 134 (2023)
   PUBMED   36797258
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2267)
  AUTHORS   Cecchini K, Biasini A, Yu T, Saflund M, Mou H, Arif A, Eghbali A,
            Colpan C, Gainetdinov I, de Rooij DG, Weng Z, Zamore PD and Ozata
            DM.
  TITLE     The transcription factor TCFL5 responds to A-MYB to elaborate the
            male meiotic program in mice
  JOURNAL   Reproduction 165 (2), 183-196 (2023)
   PUBMED   36395073
  REMARK    GeneRIF: The transcription factor TCFL5 responds to A-MYB to
            elaborate the male meiotic program in mice.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2267)
  AUTHORS   Yu T, Biasini A, Cecchini K, Saflund M, Mou H, Arif A, Eghbali A,
            de Rooij D, Weng Z, Zamore PD and Ozata DM.
  TITLE     A-MYB/TCFL5 regulatory architecture ensures the production of
            pachytene piRNAs in placental mammals
  JOURNAL   RNA 29 (1), 30-43 (2022)
   PUBMED   36241367
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   4  (bases 1 to 2267)
  AUTHORS   Galan-Martinez J, Berenguer I, Del Carmen Maza M, Stamatakis K,
            Girones N and Fresno M.
  TITLE     TCFL5 deficiency impairs the pachytene to diplotene transition
            during spermatogenesis in the mouse
  JOURNAL   Sci Rep 12 (1), 10956 (2022)
   PUBMED   35768632
  REMARK    GeneRIF: TCFL5 deficiency impairs the pachytene to diplotene
            transition during spermatogenesis in the mouse.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2267)
  AUTHORS   Xu W, Zhang Y, Qin D, Gui Y, Wang S, Du G, Yang F, Li L, Yuan S,
            Wang M and Wu X.
  TITLE     Transcription factor-like 5 is a potential DNA- and RNA-binding
            protein essential for maintaining male fertility in mice
  JOURNAL   J Cell Sci 135 (3) (2022)
   PUBMED   34931239
  REMARK    GeneRIF: Transcription factor-like 5 is a potential DNA- and
            RNA-binding protein essential for maintaining male fertility in
            mice.
REFERENCE   6  (bases 1 to 2267)
  AUTHORS   Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K,
            Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre
            A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt
            AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,
            Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S,
            Wohnoutka P, Hawrylycz MJ, Puelles L and Jones AR.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   7  (bases 1 to 2267)
  AUTHORS   Gallardo TD, John GB, Shirley L, Contreras CM, Akbay EA, Haynie JM,
            Ward SE, Shidler MJ and Castrillon DH.
  TITLE     Genomewide discovery and classification of candidate ovarian
            fertility genes in the mouse
  JOURNAL   Genetics 177 (1), 179-194 (2007)
   PUBMED   17660561
  REMARK    GeneRIF: Transcripts highly enriched in ovary; gene identified as
            candidate female fertility factor.
REFERENCE   8  (bases 1 to 2267)
  AUTHORS   Ballow D, Meistrich ML, Matzuk M and Rajkovic A.
  TITLE     Sohlh1 is essential for spermatogonial differentiation
  JOURNAL   Dev Biol 294 (1), 161-167 (2006)
   PUBMED   16564520
REFERENCE   9  (bases 1 to 2267)
  AUTHORS   Willnow T, Antignac C, Brandli A, Christensen E, Cox R, Davidson D,
            Davies J, Devuyst O, Eichele G, Hastie N, Verroust P, Schedl A and
            Meij I.
  TITLE     The European renal genome project: an integrated approach towards
            understanding the genetics of kidney development and disease
  JOURNAL   Organogenesis 2 (2), 42-47 (2005)
   PUBMED   19521566
REFERENCE   10 (bases 1 to 2267)
  AUTHORS   Siep M, Sleddens-Linkels E, Mulders S, van Eenennaam H, Wassenaar
            E, Van Cappellen WA, Hoogerbrugge J, Grootegoed JA and Baarends WM.
  TITLE     Basic helix-loop-helix transcription factor Tcfl5 interacts with
            the Calmegin gene promoter in mouse spermatogenesis
  JOURNAL   Nucleic Acids Res 32 (21), 6425-6436 (2004)
   PUBMED   15585666
  REMARK    GeneRIF: Tcfl5 is a testis-specific transcription factor that
            interacts with the calmegin gene promoter during spermatogenesis.
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL732560.11 and AL669926.6.
            
            On Jul 19, 2022 this sequence version replaced NM_001360335.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY234363.1, SRR15390195.729691.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164142 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-772               AL732560.11        4275-5046           c
            773-956             AL732560.11        3180-3363           c
            957-1119            AL732560.11        2600-2762           c
            1120-1366           AL669926.6         225557-225803       c
            1367-1508           AL669926.6         222407-222548       c
            1509-2267           AL669926.6         209109-209867       c
FEATURES             Location/Qualifiers
     source          1..2267
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 103.16 cM"
     gene            1..2267
                     /gene="Tcfl5"
                     /gene_synonym="Figlb; Sosf1"
                     /note="transcription factor-like 5 (basic
                     helix-loop-helix)"
                     /db_xref="GeneID:277353"
                     /db_xref="MGI:MGI:2672878"
     exon            1..772
                     /gene="Tcfl5"
                     /gene_synonym="Figlb; Sosf1"
                     /inference="alignment:Splign:2.1.0"
     exon            773..956
                     /gene="Tcfl5"
                     /gene_synonym="Figlb; Sosf1"
                     /inference="alignment:Splign:2.1.0"
     exon            957..1119
                     /gene="Tcfl5"
                     /gene_synonym="Figlb; Sosf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1120..1366
                     /gene="Tcfl5"
                     /gene_synonym="Figlb; Sosf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1367..1508
                     /gene="Tcfl5"
                     /gene_synonym="Figlb; Sosf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1509..2267
                     /gene="Tcfl5"
                     /gene_synonym="Figlb; Sosf1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actgctcctg aggtgctcag cggtttccct cccccaacgg cgcgcccgcg gtggccggcg
       61 cgtcgtctgc ggaggccgcg accccgcctc gccgcccgcc cgcgtctgcg tcgccgtccc
      121 cgcgcccgcg ccccgccgtt gggccgcgcc gcgccggcat gtcgggcccc gggccgcggg
      181 agccgccgcc tgaggcgggc gcgacgggcg gcgaggcggg ccccgagggc gcgggcggcg
      241 gggacgcggc gctgggagag ccggggctga gcttcacgac caccgacctg agcctggtgg
      301 agatgacgga agtggagtac acgcagctgc agcacatcct ctactcgcac atggaggcgg
      361 cggacggcga gctcgaggcg cgcctgggct ccgcgctgct ggccggcccg ggcgcgggct
      421 cgggcgcggc gggctcgctg gcgccggcgc cgcccgtgta cccagtgctg tgcccgccgc
      481 tggcggccga cgcgccgtgc ctgggccacg tcgacttcca ggagctgcgt atgatgctgc
      541 tgggcgaggc gggcgcggcg gagaagacgc ccggcggtgc ggacgggacg cggacgcggg
      601 cggacggcgt ggccaaggaa ggcgcgggcg gtgcggggcc cgacggcgca ccggaggccc
      661 gggccaagcc gaccgtacgc gtccgtctgg aggaccgctt caacagtatg ccggccgagc
      721 cgcctgcgcc gcgcggtgct gagcccgccg agtcgggcgt ggcgctcaac aatttggtaa
      781 ctcttattcg acatccatct gaattaatga atgttcctct tcaccagcaa caaaacaaat
      841 gtacgacctt agtgaaaaat aaaactgctg ctgccactac tgctttgcag ttcacctacc
      901 cactgtttac aagtgcctgc tccactggtg ggaatgccag ccttgcacag acgcagagtt
      961 ctagtaactc atgctctata ctggaagctg ccaagcacca ggatattgga ctgcctagag
     1021 cattttcttt ctgttaccag caagagattg agtccaccaa acagacagga ggtagtagaa
     1081 acaaagcctt gccggagcag gtttggatta aagtgggaga agaagcgcta tgtaaacaag
     1141 caatcaataa gaggaatcgg agtagaatcc gccagctgga cacaagcgtg gagcgaagag
     1201 cccttggaga gattcagaat gtaggtgaag gctcttcaac atcacagggc acctggcagt
     1261 cttcagagtc ctcacagtca aacctggggg agcagacgca gagcggaccc cagggaggaa
     1321 ggtctcagcg tcgggagagg cataaccgaa tggaacgaga taggaggcgc agaatccgca
     1381 tttgctgtga tgagctgaat cttttagttc cattctgcaa tgcggagaca gataaagcaa
     1441 caacccttca gtggaccaca gcattcctga agtacattca ggaaagacat ggggactctc
     1501 ttaaaaagga atttgagagc gtgttttgcg gtaaaactgg cagaaggcta aagctgacta
     1561 gacccgaatc cctggtgacc tgccctgcac agggcagcct gcagagcagc cctgccatgg
     1621 agatcaagtg actggactga cccaggacct gggagagaac cgccgttcct gcggcatcat
     1681 gcacatgcct gccatcccgg agttcagctc tgagtcctct cgagggatgc ggctccagtt
     1741 gtgggactcc agtaaggacg ttgagagcac atttcgtgaa agtatttatc taaacaaaat
     1801 acttacccac taatgtccga tgaccatttg aggatgaaga catcttgata attagtaatt
     1861 tttcaattac ctgtccgaca ccatcatgtg ttcttaacat gataactttt aaaaaattaa
     1921 catccttggt aatttcttga gtcttgagac taaagaaaac attgccgttt acttattttg
     1981 tttacatttt aaatgtgccc ctttagcaat tggaagaagg taaattgttc ttaactagaa
     2041 gaggtttgga aactttattt catttgttct gtccccccta tttccagtct catggtactc
     2101 tattggaaaa tgcagtgcca ttttaaaact ttgctaagaa ttttccagag acttctttta
     2161 aagctccttt tgcccataaa cattttcgca gtacattgct ttaatgccca catttccata
     2221 ttgtgaggca gtgctttatg tgtaataaac tgtatgtttg gaacaaa
//
