LOCUS       NM_011545               1254 bp    mRNA    linear   ROD 31-DEC-2024
DEFINITION  Mus musculus transcription factor 21 (Tcf21), mRNA.
ACCESSION   NM_011545
VERSION     NM_011545.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1254)
  AUTHORS   Argiro,L., Chevalier,C., Choquet,C., Nandkishore,N., Ghata,A.,
            Baudot,A., Zaffran,S. and Lescroart,F.
  TITLE     Gastruloids are competent to specify both cardiac and skeletal
            muscle lineages
  JOURNAL   Nat Commun 15 (1), 10172 (2024)
   PUBMED   39580459
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1254)
  AUTHORS   Velez-delValle,C., Hernandez-Mosqueira,C.P., Castro-Rodriguez,L.I.,
            Vazquez-Sandoval,A., Marsch-Moreno,M. and Kuri-Harcuch,W.
  TITLE     Gene expression and characterization of clonally derived murine
            embryonic brown and brite adipocytes
  JOURNAL   FEBS Open Bio 14 (9), 1503-1525 (2024)
   PUBMED   38972757
REFERENCE   3  (bases 1 to 1254)
  AUTHORS   Dumas,C.E., Rousset,C., De Bono,C., Cortes,C., Jullian,E.,
            Lescroart,F., Zaffran,S., Adachi,N. and Kelly,R.G.
  TITLE     Retinoic acid signalling regulates branchiomeric neck muscle
            development at the head/trunk interface
  JOURNAL   Development 151 (16) (2024)
   PUBMED   39082789
REFERENCE   4  (bases 1 to 1254)
  AUTHORS   Wu,Y., Chen,S., Huang,G., Zhang,L., Zhong,L., Feng,Y., Wen,P. and
            Liu,J.
  TITLE     Transcriptome analysis reveals EBF1 ablation-induced injuries in
            cardiac system
  JOURNAL   Theranostics 14 (12), 4894-4915 (2024)
   PUBMED   39239522
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1254)
  AUTHORS   Farber,G., Dong,Y., Wang,Q., Rathod,M., Wang,H., Dixit,M.,
            Keepers,B., Xie,Y., Butz,K., Polacheck,W.J., Liu,J. and Qian,L.
  TITLE     Direct conversion of cardiac fibroblasts into endothelial-like
            cells using Sox17 and Erg
  JOURNAL   Nat Commun 15 (1), 4170 (2024)
   PUBMED   38755186
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1254)
  AUTHORS   Quaggin,S.E., Schwartz,L., Cui,S., Igarashi,P., Deimling,J.,
            Post,M. and Rossant,J.
  TITLE     The basic-helix-loop-helix protein pod1 is critically important for
            kidney and lung organogenesis
  JOURNAL   Development 126 (24), 5771-5783 (1999)
   PUBMED   10572052
REFERENCE   7  (bases 1 to 1254)
  AUTHORS   Robb,L., Mifsud,L., Hartley,L., Biben,C., Copeland,N.G.,
            Gilbert,D.J., Jenkins,N.A. and Harvey,R.P.
  TITLE     epicardin: A novel basic helix-loop-helix transcription factor gene
            expressed in epicardium, branchial arch myoblasts, and mesenchyme
            of developing lung, gut, kidney, and gonads
  JOURNAL   Dev Dyn 213 (1), 105-113 (1998)
   PUBMED   9733105
REFERENCE   8  (bases 1 to 1254)
  AUTHORS   Hidai,H., Bardales,R., Goodwin,R., Quertermous,T. and
            Quertermous,E.E.
  TITLE     Cloning of capsulin, a basic helix-loop-helix factor expressed in
            progenitor cells of the pericardium and the coronary arteries
  JOURNAL   Mech Dev 73 (1), 33-43 (1998)
   PUBMED   9545526
REFERENCE   9  (bases 1 to 1254)
  AUTHORS   Lu,J., Richardson,J.A. and Olson,E.N.
  TITLE     Capsulin: a novel bHLH transcription factor expressed in epicardial
            progenitors and mesenchyme of visceral organs
  JOURNAL   Mech Dev 73 (1), 23-32 (1998)
   PUBMED   9545521
REFERENCE   10 (bases 1 to 1254)
  AUTHORS   Quaggin,S.E., Vanden Heuvel,G.B. and Igarashi,P.
  TITLE     Pod-1, a mesoderm-specific basic-helix-loop-helix protein expressed
            in mesenchymal and glomerular epithelial cells in the developing
            kidney
  JOURNAL   Mech Dev 71 (1-2), 37-48 (1998)
   PUBMED   9507058
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK011575.1 and AF035717.1.
            
            On Jun 23, 2018 this sequence version replaced NM_011545.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC053525.1, AF036945.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                AK011575.1         2-16
            16-1254             AF035717.1         1-1239
FEATURES             Location/Qualifiers
     source          1..1254
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 10.33 cM"
     gene            1..1254
                     /gene="Tcf21"
                     /gene_synonym="bHLHa23; capsulin; epc; epicardin; Pod-1;
                     Pod1"
                     /note="transcription factor 21"
                     /db_xref="GeneID:21412"
                     /db_xref="MGI:MGI:1202715"
     exon            1..690
                     /gene="Tcf21"
                     /gene_synonym="bHLHa23; capsulin; epc; epicardin; Pod-1;
                     Pod1"
                     /inference="alignment:Splign:2.1.0"
     CDS             241..780
                     /gene="Tcf21"
                     /gene_synonym="bHLHa23; capsulin; epc; epicardin; Pod-1;
                     Pod1"
                     /note="podocyte-expressed 1"
                     /codon_start=1
                     /product="transcription factor 21"
                     /protein_id="NP_035675.1"
                     /db_xref="CCDS:CCDS23732.1"
                     /db_xref="GeneID:21412"
                     /db_xref="MGI:MGI:1202715"
                     /translation="MSTGSLSDVEDLQEVEMLDCDSLKVDSNKEFGTSNESTEEGSNC
                     ENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRL
                     KTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKP
                     ENDLKEVVTANRLCGTTAS"
     exon            691..1254
                     /gene="Tcf21"
                     /gene_synonym="bHLHa23; capsulin; epc; epicardin; Pod-1;
                     Pod1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgctcttt cactctccgt taaggccagg actccagtgg tggggagata gagcactggt
       61 ttccctgtcg cgggatccct tgtgatcgtt ttccacgact ctgtaaaggg aaagctgggg
      121 gacgggactg ccagatccca cctcaaaccc aacacacgaa gtggcagctc caaacttttg
      181 agaccctttc gtttccgttt cagcgtctct ctctccctcc ctccctccac ctctctaaac
      241 atgtccactg gctccctcag cgatgtagaa gaccttcaag aggtggagat gctggactgt
      301 gactccctga aagtggactc caacaaggag tttggaactt ccaacgagag caccgaggag
      361 ggctccaact gcgagaacgg gtctccacag aagggtcgcg gtggcctagg caagaggagg
      421 aaggcgccca ctaagaaaag cccgctcagc ggggtcagcc aggagggcaa gcaggtccag
      481 cgcaacgcgg ccaatgctcg tgagcgggcc cgcatgcggg tgctgagcaa ggccttctcc
      541 aggctcaaga ccaccctgcc ctgggtgccc ccggacacca agctctccaa gctggacact
      601 ctcaggctgg cgtccagcta catcgctcac ttaaggcaga tcctggccaa cgacaagtac
      661 gagaacggtt acattcaccc agtcaacctg acgtggccct ttatggtggc cggcaaacca
      721 gagaatgacc tgaaggaagt ggtgaccgcc aaccgcttgt gtggaactac agcatcctga
      781 ccttggaggt gcgagtctgg gaaccgtgag ctctgggggc agtgggccgg caagggtgac
      841 gacccctgcc cttccctccc tgcctctgct ggtgccttgc atcgctcctc tccctatccc
      901 accccgcaag aacacttaac tgcgacgagg agattcgttt ccaaaccaaa ggagaccaac
      961 tgtacttacc gattctcatc tatttaactt gattaacttc tgccatgaat gactgcaagc
     1021 ctggctggtc caagtgcaat atgtaattat atatatatat tatatataaa tagataagaa
     1081 gagcctatca atgtgtatct tttgtacaat atgttgtaaa atgtagatca tagaatagct
     1141 gactttgaca gtcacattta taaaataagt cactcgaaga aatatatttt tttcaaacag
     1201 gttttgctac ttccgaaaat aaatctttct ttatattgaa aaaaaaaaaa aaaa
//
