LOCUS       NM_001402838            7695 bp    mRNA    linear   ROD 07-MAY-2024
DEFINITION  Mus musculus transcription factor 20 (Tcf20), transcript variant 3,
            mRNA.
ACCESSION   NM_001402838 XM_011245551
VERSION     NM_001402838.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7695)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 7695)
  AUTHORS   Cordoba-Jover,B., Ribera,J., Portoles,I., Lecue,E.,
            Rodriguez-Vita,J., Perez-Sisques,L., Mannara,F.,
            Solsona-Vilarrasa,E., Garcia-Ruiz,C., Fernandez-Checa,J.C.,
            Casals,G., Rodriguez-Revenga,L., Alvarez-Mora,M.I.,
            Arteche-Lopez,A., Diaz de Bustamante,A., Calvo,R., Pujol,A.,
            Azkargorta,M., Elortza,F., Malagelada,C., Pinyol,R.,
            Huguet-Pradell,J., Melgar-Lesmes,P., Jimenez,W. and Morales-Ruiz,M.
  TITLE     Tcf20 deficiency is associated with increased liver fibrogenesis
            and alterations in mitochondrial metabolism in mice and humans
  JOURNAL   Liver Int 43 (8), 1822-1836 (2023)
   PUBMED   37312667
REFERENCE   3  (bases 1 to 7695)
  AUTHORS   Wang,N., Langfelder,P., Stricos,M., Ramanathan,L., Richman,J.B.,
            Vaca,R., Plascencia,M., Gu,X., Zhang,S., Tamai,T.K., Zhang,L.,
            Gao,F., Ouk,K., Lu,X., Ivanov,L.V., Vogt,T.F., Lu,Q.R.,
            Morton,A.J., Colwell,C.S., Aaronson,J.S., Rosinski,J., Horvath,S.
            and Yang,X.W.
  TITLE     Mapping brain gene coexpression in daytime transcriptomes unveils
            diurnal molecular networks and deciphers perturbation gene
            signatures
  JOURNAL   Neuron 110 (20), 3318-3338 (2022)
   PUBMED   36265442
REFERENCE   4  (bases 1 to 7695)
  AUTHORS   Zhou,J., Hamdan,H., Yalamanchili,H.K., Pang,K., Pohodich,A.E.,
            Lopez,J., Shao,Y., Oses-Prieto,J.A., Li,L., Kim,W., Durham,M.A.,
            Bajikar,S.S., Palmer,D.J., Ng,P., Thompson,M.L., Bebin,E.M.,
            Muller,A.J., Kuechler,A., Kampmeier,A., Haack,T.B.,
            Burlingame,A.L., Liu,Z., Rasband,M.N. and Zoghbi,H.Y.
  TITLE     Disruption of MeCP2-TCF20 complex underlies distinct
            neurodevelopmental disorders
  JOURNAL   Proc Natl Acad Sci U S A 119 (4) (2022)
   PUBMED   35074918
  REMARK    GeneRIF: Disruption of MeCP2-TCF20 complex underlies distinct
            neurodevelopmental disorders.
REFERENCE   5  (bases 1 to 7695)
  AUTHORS   Feng,C., Zhao,J., Ji,F., Su,L., Chen,Y. and Jiao,J.
  TITLE     TCF20 dysfunction leads to cortical neurogenesis defects and
            autistic-like behaviors in mice
  JOURNAL   EMBO Rep 21 (8), e49239 (2020)
   PUBMED   32510763
  REMARK    GeneRIF: TCF20 dysfunction leads to cortical neurogenesis defects
            and autistic-like behaviors in mice.
REFERENCE   6  (bases 1 to 7695)
  AUTHORS   Slager,R.E., Newton,T.L., Vlangos,C.N., Finucane,B. and Elsea,S.H.
  TITLE     Mutations in RAI1 associated with Smith-Magenis syndrome
  JOURNAL   Nat Genet 33 (4), 466-468 (2003)
   PUBMED   12652298
REFERENCE   7  (bases 1 to 7695)
  AUTHORS   Rekdal,C., Sjottem,E. and Johansen,T.
  TITLE     The nuclear factor SPBP contains different functional domains and
            stimulates the activity of various transcriptional activators
  JOURNAL   J Biol Chem 275 (51), 40288-40300 (2000)
   PUBMED   10995766
REFERENCE   8  (bases 1 to 7695)
  AUTHORS   Lyngso,C., Bouteiller,G., Damgaard,C.K., Ryom,D., Sanchez-Munoz,S.,
            Norby,P.L., Bonven,B.J. and Jorgensen,P.
  TITLE     Interaction between the transcription factor SPBP and the positive
            cofactor RNF4. An interplay between protein binding zinc fingers
  JOURNAL   J Biol Chem 275 (34), 26144-26149 (2000)
   PUBMED   10849425
REFERENCE   9  (bases 1 to 7695)
  AUTHORS   Kirstein,M., Sanz,L., Quinones,S., Moscat,J., Diaz-Meco,M.T. and
            Saus,J.
  TITLE     Cross-talk between different enhancer elements during mitogenic
            induction of the human stromelysin-1 gene
  JOURNAL   J Biol Chem 271 (30), 18231-18236 (1996)
   PUBMED   8663478
REFERENCE   10 (bases 1 to 7695)
  AUTHORS   Sanz,L., Moscat,J. and Diaz-Meco,M.T.
  TITLE     Molecular characterization of a novel transcription factor that
            controls stromelysin expression
  JOURNAL   Mol Cell Biol 15 (6), 3164-3170 (1995)
   PUBMED   7760812
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC129563.14 and AC087902.43.
            
            On Mar 23, 2022 this sequence version replaced XM_011245551.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660825.5437.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164142 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-315               AC129563.14        76354-76668         c
            316-6087            AC129563.14        28365-34136         c
            6088-6181           AC087902.43        196765-196858       c
            6182-6231           AC087902.43        187145-187194       c
            6232-6354           AC087902.43        186015-186137       c
            6355-7695           AC087902.43        179981-181321       c
FEATURES             Location/Qualifiers
     source          1..7695
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 38.73 cM"
     gene            1..7695
                     /gene="Tcf20"
                     /gene_synonym="2810438H08Rik; mKIAA0292; SPBP"
                     /note="transcription factor 20"
                     /db_xref="GeneID:21411"
                     /db_xref="MGI:MGI:108399"
     exon            1..315
                     /gene="Tcf20"
                     /gene_synonym="2810438H08Rik; mKIAA0292; SPBP"
                     /inference="alignment:Splign:2.1.0"
     exon            316..6087
                     /gene="Tcf20"
                     /gene_synonym="2810438H08Rik; mKIAA0292; SPBP"
                     /inference="alignment:Splign:2.1.0"
     CDS             352..6315
                     /gene="Tcf20"
                     /gene_synonym="2810438H08Rik; mKIAA0292; SPBP"
                     /note="isoform a is encoded by transcript variant 3;
                     stromelysin PDGF responsive element binding protein
                     transcription factor; TCF-20; nuclear factor SPBP;
                     SPRE-binding protein; stromelysin-1 PDGF-responsive
                     element-binding protein"
                     /codon_start=1
                     /product="transcription factor 20 isoform a"
                     /protein_id="NP_001389767.1"
                     /db_xref="GeneID:21411"
                     /db_xref="MGI:MGI:108399"
                     /translation="MQSFREQSSYHGNQQSYPQEVHSSSRIEEFSPRQAQMFQNFGGA
                     GGGSSGTGSSSSGRRGTAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDTVAAGT
                     PQPPQRRPSGPVQSYGPPQGSSFGNQYASEGHVSQFQAQHSALGGVSHYQQDYTGPFS
                     PGSAQYQQQASSQQQQQQQQQQQQQQQQQQQQVQQLRQQLYQSHQPLPQTTGQPASGS
                     SHLQPMQRPSTLPSSAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSY
                     SVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPPGNQQGQQQQQQQPQP
                     QQQQPQQQQQQQQQQQHPPQHVMQYTNAATKMPLQSQVGQYNQPEVPVRSPMQFHQNF
                     SPISNPSPAASVVQSPSCSSTPSPLMQSGENLQCGQGNVPMSSRNRILQLMPQLSPTP
                     SMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSSQVANLPNTVQHMLLSDALT
                     PQKKTSKRPSSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQL
                     SGQSTSSDTTYKCGASEKAGSSPTQGAQNEAPRLSTSPATRDEAASPGAKDTSLSSEG
                     NTKVNEKTVGVIVSREAMTGRVEKSGGQDKGSQEDDPAASQRPPSNSGVKEISHTSLP
                     QPDPPGGGSKGNKNGDNNSSNHNGEGNGPSSHSAVGPSFTGRTEPSKSPGSLRYSYKE
                     SFGSAVPRNVSGYPQYPSGQEKGDFGSHGERKGRNEKFPSLLQEVLQGYHHHPDRRYP
                     RSAQEHQGMASGLEGTARPNILVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSST
                     APEMKQINLSDYPIPRKFEIEPPSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSL
                     GHMGTDARIGRNERLNPSLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFN
                     KKSGDHCHPTSIKHETYRGNASPGAAAHDSISDYGPQDSRSTPMRRVPGRVGSRETMR
                     GRSSSQYHDFAEKLKMSPGRSRGPGGDPHHMNPHMTFSERANRSSLHAPFSPNSESLA
                     SAYHTNTRAHAYGDPNTGLNSQLHYKRQMYQQQQEEYKDWASSSAQGVIAAAQHRQEG
                     PRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSTQEAGRCLMSSDGLPAKSME
                     LKHSSQKLQESCWDLSRQTSPAKSSGPPGMSNQKRYGPPHEPDGHGLAESAQSSKPSN
                     VMLRLPGQEDHSSQNPLIMRRRVRSFISPIPSKRQSQDVKNSNADDKGRLLHPSKEGA
                     DKAYNSYSHLSHSQDIKSIPKRDSSKDLPNPDNRNCPAVTLTSPAKTKILPPRKGRGL
                     KLEAIVQKITSPNIRRSASANSAEAGGDTVTLDDILSLKSGPPEGGTVATQEAEMEKR
                     KCEVVSDLVSVTNQESNVEKPLPGPSEEWRGSGDDKVKTEAHVETASTGKEPSGTMTS
                     TASQKPGGNQGRPDGSLGGAAPLIFPDSKNVAPVGILAPEANPKAEEKENDTVMISPK
                     QESFPPKGYFPSGKKKGRPIGSVNKQKKQQQQPPPPPQPPQMPEGSADGEPKPKKQRQ
                     RRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQPLDKTDAKNKSFFPYIHVVNK
                     CELGAVCTIINAEEEEQTKLVRSRKGQRSLTPPPSSTESKVLPASSFMLQGPVVTESS
                     VMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPKRSSEMQSKVKVRHKSA
                     SNGSKTDTEEEEEQQQQKEQRSLAAHPRFKRRHRSEDCGGGPRSLSRGLPCKKAATEG
                     SSEKTVSDTKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCILWANGIYLVCGRLY
                     GLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLLHEENFSVRCPK
                     HKPPLPCPLPPLQNKTAKGSLSTEQSERG"
     exon            6088..6181
                     /gene="Tcf20"
                     /gene_synonym="2810438H08Rik; mKIAA0292; SPBP"
                     /inference="alignment:Splign:2.1.0"
     exon            6182..6231
                     /gene="Tcf20"
                     /gene_synonym="2810438H08Rik; mKIAA0292; SPBP"
                     /inference="alignment:Splign:2.1.0"
     exon            6232..6354
                     /gene="Tcf20"
                     /gene_synonym="2810438H08Rik; mKIAA0292; SPBP"
                     /inference="alignment:Splign:2.1.0"
     exon            6355..7695
                     /gene="Tcf20"
                     /gene_synonym="2810438H08Rik; mKIAA0292; SPBP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7674..7679
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tcf20"
                     /gene_synonym="2810438H08Rik; mKIAA0292; SPBP"
                     /note="hexamer: AATAAA"
     polyA_site      7695
                     /gene="Tcf20"
                     /gene_synonym="2810438H08Rik; mKIAA0292; SPBP"
                     /note="major polyA site"
ORIGIN      
        1 gctctgttat ttcctgtgtg ttgggagaat ggagagaaaa aacccggagc cgagccgcct
       61 tcggcccctg cgaggcggcc acggcctcag ccgggggagc cctccctgag gcgcgccgga
      121 gcggggagtg agccagcgag cgcgcgggcc ggagcgagcc tctaggggcc gcggccccgg
      181 cccgccccgc cgtcggcctg ggcgtccgcg ctggaggcgg tggaggcacc cccaccccca
      241 ccccgcgccg cgccgccgcc ccctcccctc ccagcgccgg cggaggccga gggacgggcc
      301 ggggggctcc tgcaggaggg ctgctggcct gctgctgtgc tgctgaacag tatgcagtcg
      361 tttcgggagc aaagcagtta ccacggaaac cagcagagct acccacagga ggtgcacagc
      421 tcatcccgca tagaagagtt cagccctcgc caggcccaga tgttccagaa ttttggggga
      481 gcaggtggtg gtagtagtgg cactggcagc agcagtagcg gtcgacgagg aacagctgct
      541 gcagcggcag caatggctag tgagacctct ggccatcaag gctatcaggg tttcaggaaa
      601 gaagctggag atttttacta catggcaggc aacaaagaca cagtggcagc aggaacccca
      661 cagcctcctc agcgaaggcc ttctgggcct gtacagagct atggacctcc ccaggggagc
      721 agctttggca atcagtatgc gagtgagggt catgtgagcc aatttcaagc acagcactct
      781 gcccttggtg gtgtgtctca ttatcagcag gattacacag ggcctttctc tcctgggagt
      841 gctcagtatc aacagcaggc ctctagccaa caacagcagc agcagcagca gcagcaacag
      901 cagcagcagc agcaacagca gcagcaagta cagcagttga gacaacagct ttaccaatcc
      961 catcagcctc tgccacaaac cactggacag ccagcctctg gctcatcgca tctacaacca
     1021 atgcagcggc cctcaactct gccatcttct gctggttatc agttaagagt aggtcagttt
     1081 ggacagcact accagtcttc tgcttcctcc tcttcctcct cctccttccc ttctccacag
     1141 cgtttcagtc agtctggaca aagctatgat ggcagttaca gtgtgaatgc tggatctcag
     1201 tatgaagggc ataatgtggg ttctaatgca caggcttatg gaacacaatc aaattatagc
     1261 tatcaacctc agtctatgaa aaattttgaa caggcaaaga ttccaccagg aaaccagcag
     1321 gggcagcagc agcaacagca gcaaccacaa cctcagcaac agcagccgca gcaacagcag
     1381 caacagcagc agcagcagca acatcctccc cagcatgtga tgcagtacac aaatgctgcc
     1441 accaagatgc ctctgcaaag ccaggttggg cagtacaacc agcctgaggt tcctgtaagg
     1501 tctcccatgc agttccacca gaatttcagc cctatttcta acccttctcc agctgcttct
     1561 gtggttcagt ctccaagctg tagctctaca ccttctcctc tcatgcagag tggtgagaat
     1621 ctccagtgtg ggcaaggcaa tgtgcccatg agttccagaa accgaatttt acagctaatg
     1681 ccccagctca gtccaactcc atcaatgatg cccagtccta actctcatgc tgcaggattc
     1741 aaaggatttg gattagaagg ggtgccggaa aagcggctga ctgatcctgg gttgagtagt
     1801 ttgagtgctt tgagtagtca agtggccaat cttcctaata ctgtccagca catgttactt
     1861 tctgatgctt tgacacctca gaagaagacg tctaagaggc cctcatcatc atctaagaaa
     1921 gcagatagct gtacaaactc agaaggctcc tcacagcctg aagaacaact aaagtcccct
     1981 atggctgagt cattggatgg aggttgctct agtagttcag aagatcaagg tgagagggtg
     2041 aggcaactga gtggccagag cactagctct gacaccacct ataagtgtgg cgcttcagag
     2101 aaagctggct cctcaccaac acaaggtgct cagaatgagg cccctaggct cagtaccagt
     2161 cctgcaacta gggacgaagc tgcctctcca ggtgctaagg acacatcact gtcatctgag
     2221 gggaacacaa aagtcaatga gaagacagtt ggggtgattg tctcccgaga agccatgaca
     2281 ggtcgggtag aaaaatctgg tggacaagat aaaggctccc aggaggatga tcctgctgcc
     2341 agtcagagac cacctagcaa tagtggcgta aaggaaatca gccacacatc acttccacag
     2401 ccagatcctc caggaggagg gagcaaagga aacaagaatg gtgataataa tagctctaac
     2461 cacaatggag aggggaatgg cccgagtagc cactccgcag taggcccaag tttcacaggc
     2521 aggactgagc ctagcaagtc tcctggaagt ttgcgctata gttacaaaga gagttttggg
     2581 tcagctgtac cacgaaatgt cagtggttat cctcagtatc cttcaggaca agaaaagggg
     2641 gattttggca gccatggaga gcgaaagggt agaaatgaga agttcccaag tcttctacag
     2701 gaagtgcttc agggctacca ccaccatcct gacagaaggt atcctagaag cgcacaggaa
     2761 catcaaggga tggctagtgg cctggaagga actgcaaggc ctaacatctt agtcagtcaa
     2821 accaatgaat tagctagcag gggccttctg aacaagagta ttggatccct gttggaaaat
     2881 ccccactggg gaccatggga aaggaagtca agcagcacag ctcctgaaat gaaacagatc
     2941 aatttgtctg actatcccat tcccaggaag tttgagatag aacctccatc atcagcccat
     3001 gagcctggag gctccctttc tgaaaggagg tcagtaatct gtgatatatc cccactaaga
     3061 cagattgtca gggacccagg ggctcactca ttgggacaca tgggtactga tgccagaatt
     3121 gggaggaatg aacgtctcaa cccaagttta agtcagtcag tcattcttcc tggtgggttg
     3181 gtgtccatgg aaacaaaatt gaaatcccag agtggacaga taaaagagga agactttgaa
     3241 caatccaaat ctcaagctag tttcaacaag aaatctggag accactgcca tcctaccagc
     3301 atcaaacatg agacttaccg tggcaatgca agtcctggag cagcagccca tgattccatt
     3361 tcagactatg gcccacaaga tagcaggtcc acaccaatgc ggcgggtccc tggtagagtt
     3421 ggtagccggg agactatgag gggtcggtcc tcttctcagt accatgactt tgcagaaaaa
     3481 ttgaagatgt ctccaggcag gagcagaggc ccagggggag accctcatca catgaaccca
     3541 catatgacct tttcagagag ggccaatagg agttctttac atgctccttt ttctcccaac
     3601 tcagaaagcc tggcctctgc ttaccacaca aacaccaggg ctcatgctta tggggaccct
     3661 aataccggtt tgaattccca gctccattat aagagacaga tgtaccaaca gcaacaagag
     3721 gagtataaag actgggccag cagttctgct cagggagtga tcgctgctgc gcagcatagg
     3781 caggaaggcc cacgcaagag cccaaggcag cagcagtttc ttgacagagt acggagcccc
     3841 ctgaaaaatg acaaagacgg aatgatgtat ggcccaccag taggtacgta tcatgaccca
     3901 agcactcagg aagctgggcg ctgtctcatg tctagtgatg gtctgcctgc caaaagcatg
     3961 gaattgaagc acagctctca gaagttacaa gagtcttgtt gggatctttc tcggcagact
     4021 tctccagcca aaagcagtgg tcctccagga atgtctaatc aaaaacggta tgggccaccc
     4081 catgagccag atggacatgg actagccgag tctgcacagt catccaaacc tagtaacgtc
     4141 atgttacggc ttcctggtca agaggatcat tcttctcaaa atcctttaat catgcgaagg
     4201 cgggttcgtt cttttatctc ccctattccc agtaagagac agtcacaaga tgtaaaaaac
     4261 agtaacgctg atgataaagg gcgcctcctc cacccatcaa aagaaggtgc cgataaagca
     4321 tacaattcct acagccatct ttctcacagt caggatatca agtctattcc taagagagat
     4381 tcctccaagg accttccaaa cccagacaat agaaactgtc ctgctgttac cctgacaagt
     4441 cctgctaaga ccaaaatact gcccccacgg aagggacggg gattaaaatt ggaagctata
     4501 gttcagaaga tcacatctcc aaatattagg aggagtgcat ctgcaaacag tgctgaggct
     4561 gggggagaca cagtcacact ggatgatata ctatctctaa agagtggtcc tcctgaaggt
     4621 ggcactgtgg ctactcaaga ggctgagatg gaaaagcgaa agtgtgaggt ggtatctgac
     4681 ctagtcagtg taactaacca ggaatcgaat gttgagaagc ctcttccagg gccttctgaa
     4741 gagtggcgtg gcagtgggga tgacaaagtc aagacagagg cacatgtaga aacagcttct
     4801 actggaaagg aaccctctgg tactatgaca tccacagctt cacagaagcc tggtggtaac
     4861 caagggagac cagatggttc cctgggtggg gcagcaccac taatctttcc tgactcaaag
     4921 aatgtagctc cagtgggcat attggcccct gaggcaaatc ccaaggctga agagaaagag
     4981 aacgatacag tcatgatttc acccaaacaa gaaagtttcc cccctaaagg gtatttccca
     5041 tcaggaaaga aaaaggggag accaatcggt agtgtcaata agcaaaagaa acagcagcag
     5101 caaccacctc cacctcctca gccccctcag atgccagaag gttctgcaga tggggagcca
     5161 aagccaaaaa agcagaggca aaggagggag agaaggaagc ctggggccca gccaaggaag
     5221 cggaaaacca aacaagcagt tcccattgta gaacctcaag aaccagagat caagctaaag
     5281 tacgctaccc agccactaga taaaactgat gccaagaaca agtctttttt cccttacatc
     5341 catgtagtaa ataagtgtga acttggagct gtttgtacaa tcatcaatgc tgaagaagaa
     5401 gaacagacca aattggtgag gagccggaag ggtcagagat ctctgacccc tccccccagc
     5461 agcacagaaa gcaaggtgct cccagcttca tcctttatgc tgcaggggcc tgtggtaaca
     5521 gagtcttctg ttatggggca cctggtttgc tgtctctgtg gcaagtgggc cagttaccgt
     5581 aacatgggtg acctctttgg acccttttat ccccaagatt atgcagccac tcttccgaag
     5641 aatccacctc ctaagaggtc ctcagaaatg cagagcaaag tcaaggttcg gcacaaaagc
     5701 gcttctaatg gttctaaaac tgacactgag gaggaggagg agcagcagca gcagaaggag
     5761 cagaggagcc tggctgctca tcctaggttc aagcggcgcc accgctcaga agactgtggt
     5821 ggaggtcctc ggtccctgtc cagggggctc ccttgtaaaa aagcagccac ggagggcagc
     5881 agtgaaaaga ctgtttcaga cacaaagccc tctgtaccta ccacttcaga aggtgggcct
     5941 gagctggagt tacaaatccc tgaactacct cttgacagca acgaattttg ggtccatgag
     6001 ggttgtattc tctgggccaa tggaatctac ctggtctgtg gcaggctcta tggcctgcag
     6061 gaagcgctgg aaatcgccag agagatgaaa tgctcccact gccaggaggc tggcgctact
     6121 ttgggctgct acaacaaagg ctgctccttc cgataccatt acccatgtgc cattgacgca
     6181 gattgtttgc tgcatgagga gaatttctcg gtgaggtgcc ccaagcacaa gcctcccctt
     6241 ccatgccctc tccccccctt gcagaacaag accgcaaaag gcagcctcag cacagagcag
     6301 tccgagcggg ggtgaggggg gaagtgtgca cgtgggaatg gacagcaagc acaggtgaga
     6361 ctgtggagat gagaaggtgg aggacacacg tgacggaatg gaatcctcct gctgtgcaac
     6421 cacaccccac tctgccctgc cctgccctgc accccccgct gcgctgcgcc tgcccatgcc
     6481 agcacttcct tcctatgttc tcacatcaca ctcaaactgg tgacaccaca ggaaaagaaa
     6541 gatacaagat gttggaatgg ctgtttccat ggacacaatc tccatagtga caatgtgggg
     6601 gaggggggag gggagggctg atggggaaac ggggagttaa aagggaggga taaaaaatat
     6661 atatatataa atctattttt agtctggaaa gactttgttt aaatgaaagg tgcgctatcc
     6721 cttttgattc tattttaaaa ttatctagtt aattcaaaat ttgttccaat gacaatgaaa
     6781 tttaaatgtg aaattgaact gaacaaactc atctcataaa ggatggggtg tggctttgat
     6841 ctttagcctg tctcacaatt cagtgaacac tagaccctgg actgaaagag tagacaaatg
     6901 acaaccaccc ttcccttggt tagaatctgt ctcacagggg aagtttgagg gagggggaca
     6961 gaatggggat ggtcattttc aaaagtgtgg ggaatgatgt ttaaacacaa ataaattttt
     7021 ttctttccag aaacactatt tatttatttt tattttttcc ctcctttttt tttttttttg
     7081 cggggggtgg ggtggtagtg gtgaaattgg cagatgcccc aacatcatgg ctgtatcctg
     7141 gatcactgtg gccccaccaa gtatgtagag tagccccaca gcagtaggtg tacccaagga
     7201 atggcttatc tctggcgccc tctttccttg gcacattcca tgtagttggt acccttgtgg
     7261 ggacccacag catccatgga aaccatggag gcccaggcct ctgctgctga aacaagcaga
     7321 gtctaggaga gaactgtggc gtgagccatg tgggtgcact aagctgacca gagccagcca
     7381 ctttaacact tctctattgc ttttattttt tagagtggaa aggggacttg tcagatatgt
     7441 tgcccatgct atgtgattct ttatgttgta ttgttttgat ttgtaaattg tataattttt
     7501 aaatatgagt tttaaaaaaa gaaaaaagta caaaaaaaat cttgttaagg ccttaagaag
     7561 ggatatgtgc atctttcagg ggtcactctg ccgtggggat aaaatagctg ttttacaaac
     7621 agttttattt aaaaaaacaa aaatcaaaaa aattaaaaaa aaaacaaaac cgtaataaac
     7681 ttcattttaa ccttg
//
