LOCUS       NM_011544               4707 bp    mRNA    linear   ROD 16-OCT-2024
DEFINITION  Mus musculus transcription factor 12 (Tcf12), transcript variant 1,
            mRNA.
ACCESSION   NM_011544
VERSION     NM_011544.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4707)
  AUTHORS   Tousinas,G., Olumide Emmanuel,A., Tracy,M., Arnovitz,S.,
            Friedman,D., Papamarcaki,T. and Gounari,F.
  TITLE     Stabilization of beta-Catenin Directs HEB to Limit Thymic Selection
  JOURNAL   J Immunol 213 (5), 641-650 (2024)
   PUBMED   38958395
REFERENCE   2  (bases 1 to 4707)
  AUTHORS   Liu,B., He,Y., Wu,X., Lin,Z., Ma,J., Qiu,Y., Xiang,Y., Kong,F.,
            Lai,F., Pal,M., Wang,P., Ming,J., Zhang,B., Wang,Q., Wu,J., Xia,W.,
            Shen,W., Na,J., Torres-Padilla,M.E., Li,J. and Xie,W.
  TITLE     Mapping putative enhancers in mouse oocytes and early embryos
            reveals TCF3/12 as key folliculogenesis regulators
  JOURNAL   Nat Cell Biol 26 (6), 962-974 (2024)
   PUBMED   38839978
  REMARK    GeneRIF: Mapping putative enhancers in mouse oocytes and early
            embryos reveals TCF3/12 as key folliculogenesis regulators.
REFERENCE   3  (bases 1 to 4707)
  AUTHORS   Talley,M.J., Nardini,D., Ehrman,L.A., Lu,Q.R. and Waclaw,R.R.
  TITLE     Distinct requirements for Tcf3 and Tcf12 during oligodendrocyte
            development in the mouse telencephalon
  JOURNAL   Neural Dev 18 (1), 5 (2023)
   PUBMED   37684687
  REMARK    GeneRIF: Distinct requirements for Tcf3 and Tcf12 during
            oligodendrocyte development in the mouse telencephalon.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4707)
  AUTHORS   Kantzer,C.G., Yang,W., Grommisch,D., Vikhe Patil,K., Mak,K.H.,
            Shirokova,V. and Genander,M.
  TITLE     ID1 and CEBPA coordinate epidermal progenitor cell differentiation
  JOURNAL   Development 149 (22) (2022)
   PUBMED   36330928
REFERENCE   5  (bases 1 to 4707)
  AUTHORS   Wang,S., Liao,Y., Zhang,H., Jiang,Y., Peng,Z., Ren,R., Li,X. and
            Wang,H.
  TITLE     Tcf12 is required to sustain myogenic genes synergism with MyoD by
            remodelling the chromatin landscape
  JOURNAL   Commun Biol 5 (1), 1201 (2022)
   PUBMED   36352000
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4707)
  AUTHORS   Hollenberg,S.M., Sternglanz,R., Cheng,P.F. and Weintraub,H.
  TITLE     Identification of a new family of tissue-specific basic
            helix-loop-helix proteins with a two-hybrid system
  JOURNAL   Mol Cell Biol 15 (7), 3813-3822 (1995)
   PUBMED   7791788
REFERENCE   7  (bases 1 to 4707)
  AUTHORS   Zhang,Y., Flejter,W.L., Barcroft,C.L., Riviere,M., Szpirer,J.,
            Szpirer,C. and Bina,M.
  TITLE     Localization of the human HTF4 transcription factors 4 gene (TCF12)
            to chromosome 15q21
  JOURNAL   Cytogenet Cell Genet 68 (3-4), 235-238 (1995)
   PUBMED   7842744
REFERENCE   8  (bases 1 to 4707)
  AUTHORS   Soosaar,A., Chiaramello,A., Zuber,M.X. and Neuman,T.
  TITLE     Expression of basic-helix-loop-helix transcription factor ME2
            during brain development and in the regions of neuronal plasticity
            in the adult brain
  JOURNAL   Brain Res Mol Brain Res 25 (1-2), 176-180 (1994)
   PUBMED   7984047
REFERENCE   9  (bases 1 to 4707)
  AUTHORS   Nielsen,A.L., Pallisgaard,N., Pedersen,F.S. and Jorgensen,P.
  TITLE     Murine helix-loop-helix transcriptional activator proteins binding
            to the E-box motif of the Akv murine leukemia virus enhancer
            identified by cDNA cloning
  JOURNAL   Mol Cell Biol 12 (8), 3449-3459 (1992)
   PUBMED   1321336
REFERENCE   10 (bases 1 to 4707)
  AUTHORS   Sun,X.H., Copeland,N.G., Jenkins,N.A. and Baltimore,D.
  TITLE     Id proteins Id1 and Id2 selectively inhibit DNA binding by one
            class of helix-loop-helix proteins
  JOURNAL   Mol Cell Biol 11 (11), 5603-5611 (1991)
   PUBMED   1922066
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY739497.1, AK143246.1, X64840.1, AK133958.1, BQ127642.1 and
            AK134502.1.
            
            On Jan 31, 2008 this sequence version replaced NM_011544.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and it encodes the longest protein (isoform 1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: M97635.1, SRR1660811.161895.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 BY739497.1         2-3
            3-591               AK143246.1         6-594
            592-2325            X64840.1           392-2125
            2326-2989           AK133958.1         1636-2299
            2990-3318           BQ127642.1         241-569
            3319-4707           AK134502.1         215-1603
FEATURES             Location/Qualifiers
     source          1..4707
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 39.85 cM"
     gene            1..4707
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /note="transcription factor 12"
                     /db_xref="GeneID:21406"
                     /db_xref="MGI:MGI:101877"
     exon            1..244
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            245..341
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     CDS             267..2387
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /note="isoform 1 is encoded by transcript variant 1;
                     TCF-12; E-box-binding protein; DNA-binding protein HTF4;
                     transcription factor HTF-4; class A helix-loop-helix
                     transcription factor ME1"
                     /codon_start=1
                     /product="transcription factor 12 isoform 1"
                     /protein_id="NP_035674.2"
                     /db_xref="CCDS:CCDS23329.1"
                     /db_xref="GeneID:21406"
                     /db_xref="MGI:MGI:101877"
                     /translation="MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSS
                     QFSGSGMDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGTHEGLSPTPF
                     MNSNLIGKTSERGSFSLYSRDSGLSGCQSSLLRQDLGLGSPAQLSSSGKPGTPYYSFS
                     ATSSRRRPLHDSVALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPT
                     SMFASTFFMQDGTHSSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGSLHSHDRLS
                     YPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQ
                     TGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRAGGQAPSSPSYENS
                     LHSLKNRVEQQLHEHLQDAMSFLKDVCEQSRMEDRLDRLDDAIHVLRNHAVGPSTSLP
                     TSHSDIHSLLGPSHNASIGNLNSNYGGSSLVTNSRSASMVGTHREDSVSLNGNHSVLS
                     STVAASNTELNHKTPENFRGGVQNQSGSVVPTEIKTENKEKDENLHEPPSSDDMKSDD
                     ESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKEL
                     GRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAAS
                     AEPPNTLPGAHPGLSESTNPMGHL"
     exon            342..414
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            415..488
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            489..591
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            592..656
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            657..792
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            793..845
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            846..951
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1091
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1236
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            1237..1301
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..1380
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            1381..1454
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            1455..1526
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            1527..1733
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            1734..1848
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            1849..2011
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            2012..2244
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            2245..2398
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     exon            2399..4707
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4565..4570
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /note="hexamer: GATAAA"
     polyA_site      4585
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /note="major polyA site"
     regulatory      4657..4662
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /note="hexamer: AATAAA"
     polyA_site      4686
                     /gene="Tcf12"
                     /gene_synonym="A130037E08Rik; ALF1; bHLHb20; HEB; HEBAlt;
                     HTF-4; HTF4; ME1; REB"
                     /note="major polyA site"
ORIGIN      
        1 ggaaaaaaaa aaaaatgtcc gcctgaggag acccacaagt tctatcgggg ggacagccag
       61 cccgcccggg gagccacggg cggctaagcc cgagagccgc ccgagtcgcg ccgactcaag
      121 cactcgcggg ggcccgaggc aacgcagccg ccggcggcgc gtggggaggg ggaaagcctg
      181 agcccgcgct cccggccaaa gtgaacttta atcgggaagg ttggatgcgg agcccgggcg
      241 gcaggacctg ctagaagtgg ctgaagatga atccccagca gcagcgcatg gccgcgatag
      301 ggaccgacaa ggagctgagc gacctgctgg acttcagtgc gatgttttct ccacctgtta
      361 atagtgggaa aacgagacca acaacactgg gaagtagtca gttcagcggg tcaggtatgg
      421 atgagcgtgg aggaacaaca tcttggggaa caagtggtca accaagcccc tcctatgatt
      481 catctagagg ttttacagac agccctcatt acagtgatca cttgaatgac agtcgattag
      541 gaacccacga aggcttgtcc ccaacacctt tcatgaactc aaatctgata gggaaaacat
      601 cagagagagg ctcattttcc ctgtacagca gagactctgg actctcaggc tgtcagtcta
      661 gtctcctgag acaagatcta ggacttggga gcccggcaca gctgtcttct tcaggaaagc
      721 ctggaacacc atactactca ttctctgcca caagttcgag aagaagaccg ctccatgatt
      781 ctgtagccct agatccttta caagcgaaga aagtaagaaa ggtgcctcct ggcctacctt
      841 cttctgtata tgcaccatcc ccaaattctg acgatttcaa ccgtgaatct cctagttacc
      901 catctcccaa gccaccaacc agtatgttcg ctagcacttt ctttatgcaa gatgggaccc
      961 acagttcttc tgacctttgg agttcatcga atgggatgag ccagcctggt tttggtggaa
     1021 ttctggggac ctccacatcc cacatgtctc agtccagtag ttatggcagc cttcattcac
     1081 atgaccgctt gagttatcct ccacactcag tgtcaccaac agacataaac acaagtcttc
     1141 cgccaatgtc cagcttccac cgtggtagta ccagcagctc accatatgtt gccgcctcac
     1201 atactcctcc catcaatgga tcagatagca tcctaggaac cagagggaat gctgctggaa
     1261 gctcacagac gggtgatgca cttgggaagg ccttggcatc tatttattcc cctgaccaca
     1321 caagcagtag ttttccatca aacccatcaa caccagtggg atctccttca cctctcacag
     1381 gtaccagtca gtggcccaga gctggagggc aagctccttc atctccaagc tatgaaaact
     1441 cacttcactc cctgaaaaat cgagttgagc agcaacttca cgagcatttg caagatgcaa
     1501 tgtccttctt aaaggatgtc tgtgagcagt ctcgaatgga agaccgctta gacaggctgg
     1561 atgatgctat ccatgtgcta cgaaaccatg cagttggacc ttctaccagt ctgcctacta
     1621 gccacagtga catacacagt ttgctgggac catcccataa tgcatcaatt ggaaacctca
     1681 attcaaacta tggaggatcc agccttgtta caaatagtcg atcagcttcg atggtcggaa
     1741 cacatcggga agattcagtc agtctcaatg gcaatcattc ggtcctgtct agtactgttg
     1801 ctgcctcaaa cacagaactg aaccataaaa caccagaaaa tttcagaggt ggtgtacaaa
     1861 atcagtctgg aagtgttgtt ccaacagaaa tcaagactga aaacaaagaa aaagatgaaa
     1921 accttcatga acctccttca tcagatgaca tgaaatcaga tgatgagtcc tcccagaaag
     1981 acatcaaggt ctcatctagg ggcagaacaa gcagtaccaa tgaagacgag gatctgaatc
     2041 cagaacagaa aatcgaaagg gagaaggaaa ggcggatggc taacaatgcc agagagcgcc
     2101 tgcgcgtgcg ggatattaac gaggcgttca aggagcttgg ccgaatgtgt cagcttcatt
     2161 tgaagagtga aaaacctcag acaaaacttc tcattcttca tcaggccgtg gcagtcatcc
     2221 ttagtctaga acagcaagtg agagagagga acctcaaccc caaagcagcc tgccttaaga
     2281 gaagagaaga agaaaaagtc tctgctgcgt cagcagagcc gcccaacacg ttgccaggag
     2341 cccatcctgg gcttagtgag tctaccaacc ctatgggtca tctgtaaaca tcagccagtt
     2401 ccagagtcat cagtaggcta aatagaaggt gacctctcct cataagattt ggacaactca
     2461 gattatctga agacacaaac ctggcaggag ggagaagaaa aagcaaaaca cttgaaacca
     2521 gaaactcata tgtaatcctg tgatcaaagc aactggtcag cacttcatca gacgtgagca
     2581 taggaagctc agcagagacc gtcggccgtg aggtgtttgc agcatatcac tctgctgtaa
     2641 tcagtgtgtc gcttctgcac aatcagagac tgtctcatct ctccactcaa cgtggaagtt
     2701 gccttgtgcc taaactgaat tgacaaatgc attgtaacta caaattttat ttattgttat
     2761 ggaactgtga ggtctacata taaagggaaa agttcatgtg ggaagctgat gtacactcag
     2821 ctgatgccag cattgttaaa gctgttcaca gagcagtggc aaccattggc ccttagcatt
     2881 cccggcatac ctgttagtgt cttaaaaagg aagggagtcc tttgttgccc tctccgacct
     2941 tcgccatatg aatagtgatt tccatgaaat aggaaaaata ttacttcgta tagcatttct
     3001 ctcttgtttt tttcactcat ttttatttcc tctttgtggg tgttatattt gatctgagtc
     3061 tgcatagttt atggtcacag tccagaaccc tccttgcagt cctgtatgct ttgttcatgt
     3121 ccttgaagtg ataagcagac accatctgtg accatagcct agctaatatt ttgaaagggg
     3181 aagttttgtc ccctggattt gcccccaaat aaacattgct ttatttctaa taatcactaa
     3241 gacttttcag gcttctaggt ttcatagtaa agctataata gcaagaagtg taacttacaa
     3301 gggagagttt actttttagg aattgctttg ttttccgagc agtaagtact acacaatata
     3361 gtacttgtaa agtgttagct gataagtaag cacagaatgc attcagtaca atacaaagat
     3421 gacttttcct ggtgagtctc cgggacaggc agtgtgatga atgcactcaa ccgctctgag
     3481 gctaattacc tatggaatcc aagagcaatg gtcacggttc cttaccctag ctttacttct
     3541 gtcctttgag ttggctggtc cgtggggggt ggggcaggag ggtgacttaa tcacctgcaa
     3601 accacctgcc cccaccccaa gaagagccag attagcaccg agctgtacct gtcagtctgt
     3661 cttagcatta tgcattaagg caccctctgt ctctaatccc ttacagttgt ttttaagaca
     3721 cagtaatcac tttaaacttc catgaaatct gtcttccacc acagcaccct gggagagaaa
     3781 aacatgctaa gcgtgatggt cttggctaag taactcctta aagccaatag cagtggcagt
     3841 ctgcacagaa gaaaaatccc aagtcgttct gtaacttaga gacaccggag aattttgaaa
     3901 gaacaaaaac catgaagaca gcacttcaga tcctccatca ggactctggt gaacacgtca
     3961 gtctttggcg aacttagtgg acttaatttg tatatgttct ccagttagat cagactctat
     4021 ctgtggcctt gttcttcatt tcagtgttaa tcagctaaaa cagcagttgt tgctatgatg
     4081 tgtgagtgaa cataagccac tgcctggcct tttttcttca gagcttgtcg tctttttcgc
     4141 tatattagac tttgcagtat gcccagaagc tttccttcat aaaatagaaa gaaaaaaaca
     4201 tttggcttat ttttcactgt agctagtctt ttatacaata atcttgtaag aaaatttctt
     4261 gaattctaaa tattactctt tctagatttt tgaaatcaaa agttttcagt aaaaagtttc
     4321 ttactttatt ttattatatt aggtagttaa agaaaatgta gggttattta ccataacctg
     4381 ttcattaata tcagaaattt acaatagcat tttaagagca tagtaggttc tagcatacca
     4441 tgtagttcct atggagtatt gtgagagcga attgttggag atgagctgct tttcatcttg
     4501 ttctccagtt tccattgttg gtttattgca gatttgtatt ctgtgtcaaa ttcaaggtat
     4561 tattgataaa ccttttcaac cagcagcaag aagttcaaat ttcttttttc tgtcgctgta
     4621 acagaaaaca cagtatgtat ataacattta tgtagcaata aatgtgccat cctttttttt
     4681 aacatagtaa actagtgagt tttttac
//
