LOCUS       NM_001039474            4409 bp    mRNA    linear   ROD 02-JUL-2024
DEFINITION  Mus musculus transcription elongation regulator 1 (CA150) (Tcerg1),
            transcript variant 1, mRNA.
ACCESSION   NM_001039474
VERSION     NM_001039474.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4409)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4409)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4409)
  AUTHORS   Tsyporin,J., Tastad,D., Ma,X., Nehme,A., Finn,T., Huebner,L.,
            Liu,G., Gallardo,D., Makhamreh,A., Roberts,J.M., Katzman,S.,
            Sestan,N., McConnell,S.K., Yang,Z., Qiu,S. and Chen,B.
  TITLE     Transcriptional repression by FEZF2 restricts alternative
            identities of cortical projection neurons
  JOURNAL   Cell Rep 35 (12), 109269 (2021)
   PUBMED   34161768
REFERENCE   4  (bases 1 to 4409)
  AUTHORS   Xu,J., Huang,L. and Shakhnovich,E.I.
  TITLE     The ensemble folding kinetics of the FBP28 WW domain revealed by an
            all-atom Monte Carlo simulation in a knowledge-based potential
  JOURNAL   Proteins 79 (6), 1704-1714 (2011)
   PUBMED   21365688
  REMARK    GeneRIF: The study examines the order of formation of two
            beta-hairpins, the folding mechanism of each individual
            beta-hairpin, and transition state ensemble of formin-binding
            protein 28, FBP28 WW domain.
REFERENCE   5  (bases 1 to 4409)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   6  (bases 1 to 4409)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 4409)
  AUTHORS   Bohne,J., Cole,S.E., Sune,C., Lindman,B.R., Ko,V.D., Vogt,T.F. and
            Garcia-Blanco,M.A.
  TITLE     Expression analysis and mapping of the mouse and human
            transcriptional regulator CA150
  JOURNAL   Mamm Genome 11 (10), 930-933 (2000)
   PUBMED   11003711
REFERENCE   8  (bases 1 to 4409)
  AUTHORS   Macias,M.J., Gervais,V., Civera,C. and Oschkinat,H.
  TITLE     Structural analysis of WW domains and design of a WW prototype
  JOURNAL   Nat Struct Biol 7 (5), 375-379 (2000)
   PUBMED   10802733
REFERENCE   9  (bases 1 to 4409)
  AUTHORS   Shimada,M., Saito,M., Katakai,T., Shimizu,A., Ichimura,T., Omata,S.
            and Horigome,T.
  TITLE     Molecular cloning and splicing isoforms of mouse p144, a homologue
            of CA150
  JOURNAL   J Biochem 126 (6), 1033-1042 (1999)
   PUBMED   10578054
REFERENCE   10 (bases 1 to 4409)
  AUTHORS   Chan,D.C., Bedford,M.T. and Leder,P.
  TITLE     Formin binding proteins bear WWP/WW domains that bind proline-rich
            peptides and functionally resemble SH3 domains
  JOURNAL   EMBO J 15 (5), 1045-1054 (1996)
   PUBMED   8605874
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ052824.1, AK168434.1 and AK082750.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK168434.1, SRR9219380.75106.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-23                CJ052824.1         1-23
            24-4227             AK168434.1         2-4205
            4228-4409           AK082750.1         1712-1893
FEATURES             Location/Qualifiers
     source          1..4409
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 22.66 cM"
     gene            1..4409
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /note="transcription elongation regulator 1 (CA150)"
                     /db_xref="GeneID:56070"
                     /db_xref="MGI:MGI:1926421"
     exon            1..99
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            100..325
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            326..478
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            479..938
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1181
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            1182..1244
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            1245..1445
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            1446..1558
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            1559..1647
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            1648..1808
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            1809..1865
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            1866..1932
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            1933..2068
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            2069..2158
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            2159..2277
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            2278..2428
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            2429..2593
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            2594..2776
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            2777..2956
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            2957..3040
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            3041..3141
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     exon            3142..4409
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4157..4162
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /note="hexamer: AATAAA"
     polyA_site      4178
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /note="major polyA site"
     regulatory      4207..4212
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /note="hexamer: AATATA"
     polyA_site      4229
                     /gene="Tcerg1"
                     /gene_synonym="2410022J09Rik; 2900090C16Rik; ca150;
                     CA150b; FBP23; FBP28; p144; Taf2s"
                     /note="major polyA site"
ORIGIN      
        1 gaacgccggg tcggcgggtg gatgaactcg gctgtctgta atggcggagc gtggcgggga
       61 cggaggggaa ggcgagcggt tcaacccggg ggagctgagg atggctcaac agcaggcctt
      121 gaggttccga ggcccagctc ccccaccaaa tgccgtgatg cgaggcccgc cacctctcat
      181 gagaccacct cctcctttcg gcatgatgag aggccctcct ccaccaccca ggcccccctt
      241 tggacggcct ccttttgatc ctaatatgcc accaatgcct cctccaggag gaatacctcc
      301 acctatgggc ccacctcacc tacagagacc acctttcatg cctccaccca tgggagctat
      361 gcctcctcct ccgggtatga tgttcccacc aggaatgcct ccggggactg ctcctggtgc
      421 tccagcactg cctcccactg aggagatatg ggtagaaaat aaaactccag atgggaaggt
      481 ttattactac aatgctcgga ctcgtgaatc tgcatggacc aagccagatg gagttaaggt
      541 tattcagcaa tcagaactga cgcccatgct tgcagcccaa gcacaggttc aggcccaggc
      601 ccaggcccag gcccaagcac aggctcaggc ccaggcccag gcacaagccc aggctcaggc
      661 ccaggcccag gcccaggctc aggcacaagc ccaggctcag gcccaggccc aggcccaggc
      721 tcaggctcaa gcccaagccc aagcgcaagc acaagcccag gcccaagccc aggcccaggc
      781 tcaggcccag gcacaagtcc aagcacaagc agtaggcgct cccaccccta ccaccagtag
      841 cccagcacct gcagtgtcca cgtcaactcc gacatctacc ccatcctcca ccacagctac
      901 cacgacaact gctacttcag ttgcacagac agtatcaaca cccacaacac aagaccagac
      961 cccaagttct gctgtttcag ttgccacacc tacagttagt gtttcagctc ctgctcctac
     1021 agccacacct gtgcaaaccg taccccagcc gcacccacag acgttacctc ctgctgttcc
     1081 tcactcggta cctcagccgg cagcagcaat acctgctttc ccaccagtaa tggtgcctcc
     1141 gttccgtgtg cccctgcctg gcatgccaat cccacttcca ggtgtagcaa tgatgcaaat
     1201 agtcagctgc ccgtatgtaa agacagtcgc taccaccaag accggtgtac taccaggaat
     1261 ggcccctcct atagtaccca tgatccatcc ccaggttgct attgcagctt cacctgctac
     1321 cctagctggg gcaacagcag tttctgagtg gactgaatat aaaacagcag atgggaagac
     1381 gtactattat aataatagaa cactagaatc cacgtgggag aagccccaag aactgaagga
     1441 gaaagaaaaa ttagatgaga agattaaaga accaattaag gaggcctctg aagagccatt
     1501 gccaatggag actgaggagg aagatcctaa ggaagagcct gtgaaggaga taaaggagga
     1561 gcccaaagaa gaagagatga ctgaagaaga aaaggctgcc cagaaggcaa agccagtagc
     1621 tactactcct attcctggta ctccatggtg tgttgtttgg actggtgatg agagggtctt
     1681 cttttacaat cccaccaccc gcctttctat gtgggaccgg cctgatgatt tgattggaag
     1741 ggcggatgtt gacaaaatta ttcaagagcc ccctcataag aaaggattgg aagacatgaa
     1801 gaagctaagg cacccggctc cgacaatgct gtccatccaa aagtggcagt tctcaatgag
     1861 cgcaattaaa gaagaacaag agttaatgga agaaatgaat gaagatgagc ctattaaagc
     1921 aaaaaagcgg aagagagatg ataataaaga cattgattca gagaaagaag ctgccatgga
     1981 agctgaaatt aaagctgccc gagaaagggc cattgtccct ctggaggctc gaatgaagca
     2041 gttcaaggac atgctgctag agagaggggt gtctgctttt tcaacatggg agaaagagtt
     2101 gcacaagata gtatttgacc ctcggtactt gcttctcaat cctaaagaaa gaaaacaggt
     2161 gtttgatcag tatgtcaaga ccagagcaga ggaagaacgc agggaaaaga aaaacaaaat
     2221 aatgcaagcc aaggaagatt tcaaaaaaat gatggaagaa gcaaagttta atccaagagc
     2281 tacttttagt gaatttgctg ccaaacatgc taaagattca agattcaaag caattgaaaa
     2341 gatgaaagat agagaagcat tgtttaatga gtttgtggca gctgcaagga agaaagaaaa
     2401 agaagattcg aagacgagag gggagaagat taaatcagat ttctttgaac tgttatctaa
     2461 tcatcacttg gatagtcaat ctcgatggag caaagtaaaa gacaaagtag aaagtgaccc
     2521 ccgatataaa gcggtggata gttcatcaat gagagaagac cttttcaaac agtacatcga
     2581 gaaaatagcc aagaatttag actcagaaaa agaaaaagag ctggagaggc aagcccgcat
     2641 tgaggcaagc cttcgagaac gggaaagaga agttcagaag gcgcgctctg agcagacgaa
     2701 agagatcgat cgggagagag agcagcacaa acgggaggag gctatccaga acttcaaggc
     2761 tcttctgtct gacatggtac gttcttcaga tgtgtcctgg tctgatacta ggaggaccct
     2821 ccggaaagac caccgctggg aatctgggtc cttattggaa agagaggaga aagagaaact
     2881 ttttaatgaa catattgaag cgcttaccaa aaagaaaagg gagcacttta ggcagcttct
     2941 ggacgaaacc tctgcgatta ccttaacatc cacgtggaaa gaagtgaaaa aaataattaa
     3001 ggaagatcct cggtgcatta agttctcctc cagtgacagg aaaaaacaaa gggagtttga
     3061 agaatacatc agagacaaat acatcactgc caaagctgac ttcaggacac ttttgaaaga
     3121 gaccaaattc attacataca gatccaaaaa gttaatccaa gaatctgatc agcacctgaa
     3181 agatgtagaa aagattttgc agaatgacaa acggtatcta gtactggact gtgtccccga
     3241 ggagaggagg aaactaattg tggcctatgt tgatgacctg gatcgccgag gtccaccccc
     3301 acctcccaca gcatcagagc ccactagacg atcaacaaaa taattctaaa tacccttcca
     3361 cgggctcgct gttaattgaa aatgcttgca tgagccagat tttcaggttt ttacatatat
     3421 gcattagtca acctattgca aaatcacctg acgaacagaa ggagaagcgg ttgtgggcag
     3481 tctcagaacg gaacactttg aaaatagtta atgcttttct ttgtgtggca tgactgacat
     3541 acatactcaa atataggctg tctctagtaa atttaaaatc tcgaagctaa aagtcatcct
     3601 tttataaggt gtggaagcca gtgacttggt gatgttctta ctagcagtgt tactcagcaa
     3661 gacaggagag tttgtggtag gagcttggaa ataccacaga ctccaggaaa actgaagttg
     3721 gagtttgttt ttgattttgt tttttaagcg ggtaaaagag aaaacactga attgaattct
     3781 tccagagact atggttatta taatggacgt acttttacct ttgtctctaa agagcagttt
     3841 agttgtattt gttcacgtat gtgctttgat tctcccctcc ggagttatag gccaagtctt
     3901 gtttacccca ggagaagatg tatttagtaa tttcttctca ggtatgaacc acattcataa
     3961 ctaacatgtt ggccagagtg gaatcctggt ttaaacattc tttattctcc attgaatgat
     4021 ctctaccaat attctcaatt agacaacaaa actccctttc tgggtgttcc tgtaaactac
     4081 tcctgtttga atgtttgaac ttttgtttct aaaaagttta agatgtttga atgttgaatt
     4141 tatgtatttg aactacaata aaccaaccct tttatatatg tggattgtaa atgattattg
     4201 ttacacaata tattttttaa aaactcgtag acctgttttt tattttttct ttgtttgctt
     4261 tcttgtttgg gtcattgttt ttttttttgt ttgttttgtt ttgttttgaa aaaagcatgt
     4321 gatatttgag acaacaaaat cttagaatat aggttttaaa ggcttgacta taatgctgta
     4381 tttctaatat aaaagacaag aaattttgt
//
