LOCUS       NM_025703               2256 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus transcription elongation factor A (SII)-like 8
            (Tceal8), transcript variant 2, mRNA.
ACCESSION   NM_025703 XM_906334
VERSION     NM_025703.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2256)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2256)
  AUTHORS   Navas-Perez,E., Vicente-Garcia,C., Mirra,S., Burguera,D.,
            Fernandez-Castillo,N., Ferran,J.L., Lopez-Mayorga,M.,
            Alaiz-Noya,M., Suarez-Pereira,I., Anton-Galindo,E., Ulloa,F.,
            Herrera-Ubeda,C., Cusco,P., Falcon-Moya,R., Rodriguez-Moreno,A.,
            D'Aniello,S., Cormand,B., Marfany,G., Soriano,E., Carrion,A.M.,
            Carvajal,J.J. and Garcia-Fernandez,J.
  TITLE     Characterization of an eutherian gene cluster generated after
            transposon domestication identifies Bex3 as relevant for advanced
            neurological functions
  JOURNAL   Genome Biol 21 (1), 267 (2020)
   PUBMED   33100228
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2256)
  AUTHORS   Judd,J., Lovas,J. and Huang,G.N.
  TITLE     Defined factors to reactivate cell cycle activity in adult mouse
            cardiomyocytes
  JOURNAL   Sci Rep 9 (1), 18830 (2019)
   PUBMED   31827131
  REMARK    GeneRIF: Defined factors to reactivate cell cycle activity in adult
            mouse cardiomyocytes.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2256)
  AUTHORS   Zhou,J., McCarrey,J.R. and Wang,P.J.
  TITLE     A 1.1-Mb segmental deletion on the X chromosome causes meiotic
            failure in male mice
  JOURNAL   Biol Reprod 88 (6), 159 (2013)
   PUBMED   23677977
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2256)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AA867696.1, AK076203.1 and AK083347.1.
            
            On Dec 10, 2009 this sequence version replaced NM_025703.2.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK083347.1, AK076203.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                AA867696.1         93-118
            27-609              AK076203.1         2-584
            610-2256            AK083347.1         538-2184
FEATURES             Location/Qualifiers
     source          1..2256
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 57.4 cM"
     gene            1..2256
                     /gene="Tceal8"
                     /gene_synonym="3930402F23Rik"
                     /note="transcription elongation factor A (SII)-like 8"
                     /db_xref="GeneID:66684"
                     /db_xref="MGI:MGI:1913934"
     exon            1..120
                     /gene="Tceal8"
                     /gene_synonym="3930402F23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            121..190
                     /gene="Tceal8"
                     /gene_synonym="3930402F23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            191..2256
                     /gene="Tceal8"
                     /gene_synonym="3930402F23Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             218..571
                     /gene="Tceal8"
                     /gene_synonym="3930402F23Rik"
                     /note="TCEA-like protein 8; transcription elongation
                     factor S-II protein-like 8"
                     /codon_start=1
                     /product="transcription elongation factor A protein-like
                     8"
                     /protein_id="NP_079979.2"
                     /db_xref="CCDS:CCDS30415.1"
                     /db_xref="GeneID:66684"
                     /db_xref="MGI:MGI:1913934"
                     /translation="MQKSCDENEGTPQNTPKADEGHPSEDPPQQAGETLQASGENVRE
                     ETEGSHRGEPAEPSPEPKEDTPARHLNPEEVIRGVDELERLREEIRRVRNKFVLMHWK
                     QRHSRSRPYPVCFRP"
     regulatory      886..891
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tceal8"
                     /gene_synonym="3930402F23Rik"
                     /note="hexamer: ATTATA"
     polyA_site      916
                     /gene="Tceal8"
                     /gene_synonym="3930402F23Rik"
     regulatory      1134..1139
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tceal8"
                     /gene_synonym="3930402F23Rik"
                     /note="hexamer: AATAAA"
     regulatory      1150..1155
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tceal8"
                     /gene_synonym="3930402F23Rik"
                     /note="hexamer: ATTATA"
     polyA_site      1159
                     /gene="Tceal8"
                     /gene_synonym="3930402F23Rik"
                     /note="major polyA site"
     polyA_site      1170
                     /gene="Tceal8"
                     /gene_synonym="3930402F23Rik"
ORIGIN      
        1 attgatgacg cgatcctcac gtgaccagca gtcgacgtgt gcagaagtcc ttatagtcta
       61 ggcccagttc cccagtagca gctctgtcct gctagagaag agtggcccag ctacttccag
      121 cactcttgat cttttgagcg cgacataaat cgaggtgcaa gaagagagga aaatctccag
      181 gtacctacag gattaattca ttaagaaaat aatcaacatg caaaagtctt gtgacgagaa
      241 cgaaggaaca ccccagaaca caccaaaagc agacgaaggc catccttcag aagatccacc
      301 acagcaggca ggagaaactc ttcaggcttc tggagaaaat gtgagggagg aaactgaagg
      361 gagccataga ggagagcctg ctgaacccag cccagagccc aaagaggaca ctcccgcaag
      421 gcatctgaac cccgaagaag tgataagagg cgtagatgag ttggaaaggc ttagggaaga
      481 gataagaaga gtaagaaaca agttcgtgtt gatgcattgg aagcaaagac attcccgaag
      541 ccgtccttac cctgtgtgct tcaggccttg aaatcgtttt tttctctgat attgaaatgt
      601 ggctgctgct ttctttctct tagcattttc tgatgtatct ttgaacttca ttttactttt
      661 aataataatt acctggcggt attttctgtt atgtagtttc gttgttacca gcatctcatt
      721 ggattttgga tttttgaccc attttccacg tttatctttc agttggaaag tttcacattt
      781 atgcatggaa atatacaatt agacagcaaa ttgaaaaaaa cagcagcata gttaggatca
      841 actcacatag ataggaaaat tcctaattat gtgtgtacat gtataattat acgtatcaaa
      901 aaatttacag tgcttatttt tggtgtggtg tgttttaatt ttgcctttta cttatgttga
      961 ttttttttaa tgaatacgtg tctcacaaag aactgcagat ttttttaata agtgggagtt
     1021 aattaaaatt aatttgtaac cagcttgtag aggcaataaa ggcactaaac tcttgatgaa
     1081 ctattaaaca gaaatgtaaa cctggaattc cctctggctt ccttagccag aggaataaaa
     1141 ctggcaatca ttatagacac acttggttaa gacttggtct tttcatgggg gaaatacttg
     1201 cctcacaggg atctgtgtgg aacatagtat gccatatttg agagaggaca tggcctcact
     1261 cagcctgtgt tcagatgcag aggggtgggg gctgggcttc cgtgccattt ttcttctgct
     1321 gagttcccac ccttttcttc cctgggacct gtcctgccta ccaactaggg ccaagtctgc
     1381 tggatcctgc cagtggggtc ttaagtataa agatcccgct gggtttcctt gaattccagt
     1441 tgaaccccca gccccagtgt tcagttacag gtggtgccac tatagctggc agtttgtttg
     1501 gtttgaagca atgtcttatt ctgtagccca ggctagctag gctgggattc atggcaatcc
     1561 ttcagcttct gaaatgttgg aatgttaact ccctttaact ccagtgacag gggatctggt
     1621 gcccttttct ggtctctaca cagacatggt acaaatggga ggacactgac actcttcaga
     1681 catataagaa ggtggcgtca gatcccatta cagatagtta tgagctacca tgtggttgct
     1741 aggaattgaa ctcgggacct ctggaaaagc aaccagagct cttaaccact gagccatctc
     1801 tccagccccc aacataatac acatgtattc atgcagggtc atacagattt caaaaaaagt
     1861 tttaaaaact gctctaggtt aatgattcct gcagaatcct tagcaaaagc aatcccttta
     1921 attttcaaca tggggcgttt tctctggaga ggtaataact ggataatatt aagcatattt
     1981 gaaagtagac caaggtatct gtttgaatga aaactttggg agaattcctg ggtatttagg
     2041 gtggtgttta ttgtttttat tgtgcttttt gagacagtat tccatgtacc ccagacttga
     2101 ctttgcttat taccttaagc atctgatcct caagacccct cttcccgagg gtgagcgagc
     2161 gttgcaggtg ggtgccgccg ctttcagttg atgccgggga tcagattcaa ggctttgtac
     2221 acagtaggca agcactctgc caacagagct tcacac
//
