LOCUS       NM_199059               1734 bp    mRNA    linear   ROD 31-JUL-2024
DEFINITION  Mus musculus TATA box binding protein like 2 (Tbpl2), transcript
            variant 1, mRNA.
ACCESSION   NM_199059 XM_140875
VERSION     NM_199059.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1734)
  AUTHORS   Yu,C., Cvetesic,N., Hisler,V., Gupta,K., Ye,T., Gazdag,E.,
            Negroni,L., Hajkova,P., Berger,I., Lenhard,B., Muller,F.,
            Vincent,S.D. and Tora,L.
  TITLE     TBPL2/TFIIA complex establishes the maternal transcriptome through
            oocyte-specific promoter usage
  JOURNAL   Nat Commun 11 (1), 6439 (2020)
   PUBMED   33353944
  REMARK    GeneRIF: TBPL2/TFIIA complex establishes the maternal transcriptome
            through oocyte-specific promoter usage.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1734)
  AUTHORS   Malecova,B., Dall'Agnese,A., Madaro,L., Gatto,S., Coutinho Toto,P.,
            Albini,S., Ryan,T., Tora,L. and Puri,P.L.
  TITLE     TBP/TFIID-dependent activation of MyoD target genes in skeletal
            muscle cells
  JOURNAL   Elife 5, e12534 (2016)
   PUBMED   26880551
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1734)
  AUTHORS   Hart,D.O., Santra,M.K., Raha,T. and Green,M.R.
  TITLE     Selective interaction between Trf3 and Taf3 required for early
            development and hematopoiesis
  JOURNAL   Dev Dyn 238 (10), 2540-2549 (2009)
   PUBMED   19777587
REFERENCE   4  (bases 1 to 1734)
  AUTHORS   Gazdag,E., Santenard,A., Ziegler-Birling,C., Altobelli,G., Poch,O.,
            Tora,L. and Torres-Padilla,M.E.
  TITLE     TBP2 is essential for germ cell development by regulating
            transcription and chromatin condensation in the oocyte
  JOURNAL   Genes Dev 23 (18), 2210-2223 (2009)
   PUBMED   19759265
  REMARK    GeneRIF: TBP2 binds to promoters of misregulated genes, suggesting
            that TBP2 directly regulates their expression
REFERENCE   5  (bases 1 to 1734)
  AUTHORS   Deato,M.D., Marr,M.T., Sottero,T., Inouye,C., Hu,P. and Tjian,R.
  TITLE     MyoD targets TAF3/TRF3 to activate myogenin transcription
  JOURNAL   Mol Cell 32 (1), 96-105 (2008)
   PUBMED   18851836
  REMARK    GeneRIF: properties of a TAF3/TRF3 complex in directing
            transcription initiation at the Myogenin promoter
REFERENCE   6  (bases 1 to 1734)
  AUTHORS   Di Pietro,C., Ragusa,M., Duro,L., Guglielmino,M.R., Barbagallo,D.,
            Carnemolla,A., Lagana,A., Buffa,P., Angelica,R., Rinaldi,A.,
            Calafato,M.S., Milicia,I., Caserta,C., Giugno,R., Pulvirenti,A.,
            Giunta,V., Rapisarda,A., Di Pietro,V., Grillo,A., Messina,A.,
            Ferro,A., Grzeschik,K.H. and Purrello,M.
  TITLE     Genomics, evolution, and expression of TBPL2, a member of the TBP
            family
  JOURNAL   DNA Cell Biol 26 (6), 369-385 (2007)
   PUBMED   17570761
REFERENCE   7  (bases 1 to 1734)
  AUTHORS   Tanaka,Y., Nanba,Y.A., Park,K.A., Mabuchi,T., Suenaga,Y.,
            Shiraishi,S., Shimada,M., Nakadai,T. and Tamura,T.A.
  TITLE     Transcriptional repression of the mouse wee1 gene by TBP-related
            factor 2
  JOURNAL   Biochem Biophys Res Commun 352 (1), 21-28 (2007)
   PUBMED   17109819
REFERENCE   8  (bases 1 to 1734)
  AUTHORS   Yang,Y., Cao,J., Huang,L., Fang,H.Y. and Sheng,H.Z.
  TITLE     Regulated expression of TATA-binding protein-related factor 3
            (TRF3) during early embryogenesis
  JOURNAL   Cell Res 16 (7), 610-621 (2006)
   PUBMED   16721357
  REMARK    GeneRIF: Data suggest that TRF3 plays a role in early mouse
            development, and may also be involved in Pol I transcription.
REFERENCE   9  (bases 1 to 1734)
  AUTHORS   Xiao,L., Kim,M. and DeJong,J.
  TITLE     Developmental and cell type-specific regulation of core promoter
            transcription factors in germ cells of frogs and mice
  JOURNAL   Gene Expr Patterns 6 (4), 409-419 (2006)
   PUBMED   16412700
REFERENCE   10 (bases 1 to 1734)
  AUTHORS   Persengiev,S.P., Zhu,X., Dixit,B.L., Maston,G.A., Kittler,E.L. and
            Green,M.R.
  TITLE     TRF3, a TATA-box-binding protein-related factor, is
            vertebrate-specific and widely expressed
  JOURNAL   Proc Natl Acad Sci U S A 100 (25), 14887-14891 (2003)
   PUBMED   14634207
  REMARK    GeneRIF: TRF3 is a nuclear protein that is present in all human and
            mouse tissues and cell lines examined
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL844838.7.
            
            On Jan 25, 2014 this sequence version replaced NM_199059.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY457924.1, BC119160.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-129               AL844838.7         153355-153483       c
            130-590             AL844838.7         151492-151952       c
            591-678             AL844838.7         150694-150781       c
            679-770             AL844838.7         147966-148057       c
            771-938             AL844838.7         144015-144182       c
            939-1036            AL844838.7         132892-132989       c
            1037-1734           AL844838.7         128254-128951       c
FEATURES             Location/Qualifiers
     source          1..1734
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 16.14 cM"
     gene            1..1734
                     /gene="Tbpl2"
                     /gene_synonym="Gm348; Trf3"
                     /note="TATA box binding protein like 2"
                     /db_xref="GeneID:227606"
                     /db_xref="MGI:MGI:2684058"
     exon            1..129
                     /gene="Tbpl2"
                     /gene_synonym="Gm348; Trf3"
                     /inference="alignment:Splign:2.1.0"
     CDS             61..1113
                     /gene="Tbpl2"
                     /gene_synonym="Gm348; Trf3"
                     /note="isoform 1 is encoded by transcript variant 1; TATA
                     box-binding protein-like protein 2; TBP-related factor 3
                     (Trf3); TBP-like protein 2; TATA box-binding
                     protein-related factor 3; TBP-like 2"
                     /codon_start=1
                     /product="TATA box-binding protein-like 2 isoform 1"
                     /protein_id="NP_951014.1"
                     /db_xref="CCDS:CCDS15732.1"
                     /db_xref="GeneID:227606"
                     /db_xref="MGI:MGI:2684058"
                     /translation="MVGSLIMEEDIYLDLFLDPYTIQDDFPPAMSQLFSPGVPLDMHS
                     LPSNPETVFHPHLGGVKKASTDFSSVDLSFLPDELTQENRDQTVTGNKLASEESCRTR
                     DRQSQLQLPDEHGSELNLNSNSSPDPQSCLCFDDAHSNQPSPETPNSNALPVALIASM
                     MPMNPVPGFSGIVPQLQNVVSTANLACKLDLRKIALNAKNTEYNPKRFAAVIMRIREP
                     RTTALIFSSGKVVCTGAKSEEESRLAARKYARVVQKLGFPVRFFNFKIQNMVGSCDVK
                     FPIRLEILALTHRQFSSSYEPELFPGLIYKMVKPQVVLLIFASGKVVLTGAKERSEIY
                     EAFENMYPILESFKKV"
     exon            130..590
                     /gene="Tbpl2"
                     /gene_synonym="Gm348; Trf3"
                     /inference="alignment:Splign:2.1.0"
     exon            591..678
                     /gene="Tbpl2"
                     /gene_synonym="Gm348; Trf3"
                     /inference="alignment:Splign:2.1.0"
     exon            679..770
                     /gene="Tbpl2"
                     /gene_synonym="Gm348; Trf3"
                     /inference="alignment:Splign:2.1.0"
     exon            771..938
                     /gene="Tbpl2"
                     /gene_synonym="Gm348; Trf3"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1036
                     /gene="Tbpl2"
                     /gene_synonym="Gm348; Trf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1734
                     /gene="Tbpl2"
                     /gene_synonym="Gm348; Trf3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actaacaaag cttcttccac ttgcctggac gctgattcct ttgcttgtcc tcagctctac
       61 atggtgggct ctctcatcat ggaggaggac atatacctgg acctcttcct ggatccttat
      121 accatccagg atgactttcc tccagctatg tctcaactgt tcagcccagg agtgccttta
      181 gacatgcact cacttccatc taatccagag actgtgtttc atccacatct tggtggagtc
      241 aaaaaggcat ccactgactt ttcatctgtg gatctaagct tcttaccaga tgaacttacc
      301 caagaaaata gagaccaaac tgtcactgga aacaagctgg caagtgagga aagctgtagg
      361 actcgagatc gacaaagtca gttgcagttg cccgatgaac atggcagtga gctgaacttg
      421 aatagcaaca gttcaccaga tccccagtca tgcctgtgct ttgatgatgc tcactccaac
      481 cagccctctc cagaaacacc aaactccaat gccttacctg tggcattgat agcatccatg
      541 atgccaatga accctgttcc aggattttct ggaattgtgc ctcaattaca gaatgtagtt
      601 tccactgcaa atctggcctg taaattggat ctgagaaaaa tagccctgaa tgccaaaaac
      661 acagaatata acccaaagag gtttgctgca gtaataatga ggatccgaga gccaaggaca
      721 acagctctca tctttagctc tgggaaagtg gtctgtacag gagccaaaag tgaagaggag
      781 tctcggctgg cagcgagaaa gtatgctcgt gtggtgcaga agctcgggtt ccctgtcaga
      841 ttcttcaatt ttaaaattca gaacatggtt ggaagctgtg atgtgaaatt tcccatcagg
      901 ctggagattt tggcactaac ccatcggcag ttcagtagca gttatgaacc tgaacttttc
      961 cccggcctta tttataagat ggtaaaacca caggttgtgt tgctaatctt tgcatctgga
     1021 aaagttgtgt taacaggtgc caaagagcgt tctgagatct atgaagcatt tgaaaacatg
     1081 tatcctattc tagaaagttt taagaaagtc tgagtgcatc tctgggcttc aagcaataat
     1141 ttggatatgt gattaagcac agcagagaga gctgatttct tctacacatg gctctagaag
     1201 catcctttgt tttctagcag ccatgggtct ctattattat gataattgat tatgcctttt
     1261 tgtttgattt tgccttgttt tggaaacagg gtctgctacg taacctaaaa tgtagtttga
     1321 tttattacaa aatgattctg tgtgaatagc catgattaag aaatgaaaat ttcttactca
     1381 aaatgagtat tgtatgttat ttaattataa aaaataagaa caagtaaacc tatttcagaa
     1441 tttgaaatat gtcaggcctt gctagtgtga ggcattaaga ccatgcttta tttttttaag
     1501 tatgtaatat attagtacat agaaatttca agtgaatgca tatcttgata ttacctgtaa
     1561 tgtaacagct atcaataaaa actcatgttt aatttctttt catttcaagt atagaagaga
     1621 cagcatccag accttttggt aatggatact gggaaatcac tggggtgaac caatgaaata
     1681 tcccaaacct taaaatccat tgtttgaaat aaaactgctt tccagcagcc acca
//
