LOCUS       NM_011603               2880 bp    mRNA    linear   ROD 21-DEC-2022
DEFINITION  Mus musculus TATA box binding protein-like 1 (Tbpl1), mRNA.
ACCESSION   NM_011603
VERSION     NM_011603.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2880)
  AUTHORS   Gustafson EA, Seymour KA, Sigrist K, Rooij DGDE and Freiman RN.
  TITLE     ZFP628 Is a TAF4b-Interacting Transcription Factor Required for
            Mouse Spermiogenesis
  JOURNAL   Mol Cell Biol 40 (7), e00228-19 (2020)
   PUBMED   31932482
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2880)
  AUTHORS   Menendez-Montes I, Escobar B, Palacios B, Gomez MJ,
            Izquierdo-Garcia JL, Flores L, Jimenez-Borreguero LJ, Aragones J,
            Ruiz-Cabello J, Torres M and Martin-Puig S.
  TITLE     Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch
            Essential for Cardiac Maturation
  JOURNAL   Dev Cell 39 (6), 724-739 (2016)
   PUBMED   27997827
REFERENCE   3  (bases 1 to 2880)
  AUTHORS   Nakazato A, Maeda R, Ishikawa K, Suzuki H and Tamura TA.
  TITLE     TBP-like protein (TLP) represses myogenesis via inhibition of the
            myogenin promoter
  JOURNAL   Biochem Biophys Res Commun 479 (4), 814-819 (2016)
   PUBMED   27680312
  REMARK    GeneRIF: Overexpression and knockdown of TLP revealed that the
            levels of muscle-specific myosin heavy chain and the myogenic
            transcription factor myogenin are downregulated by TLP. The
            proximal AT-rich sequence of the myogenin promoter is responsible
            for TLP-mediated transcriptional repression.
REFERENCE   4  (bases 1 to 2880)
  AUTHORS   Martianov I, Velt A, Davidson G, Choukrallah MA and Davidson I.
  TITLE     TRF2 is recruited to the pre-initiation complex as a
            testis-specific subunit of TFIIA/ALF to promote haploid cell gene
            expression
  JOURNAL   Sci Rep 6, 32069 (2016)
   PUBMED   27576952
  REMARK    GeneRIF: Trf2 forms a stable complex with TFIIA or the testis
            expressed paralogue ALF chaperoned in the cytoplasm by heat shock
            proteins. It is recruited to active haploid cell promoters together
            with Tbp, Taf7l and RNA polymerase II. A set of genes activated in
            haploid spermatids during the first wave of spermatogenesis is
            down-regulated by Trf2 inactivation.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2880)
  AUTHORS   Yabuta Y, Ohta H, Abe T, Kurimoto K, Chuma S and Saitou M.
  TITLE     TDRD5 is required for retrotransposon silencing, chromatoid body
            assembly, and spermiogenesis in mice
  JOURNAL   J Cell Biol 192 (5), 781-795 (2011)
   PUBMED   21383078
REFERENCE   6  (bases 1 to 2880)
  AUTHORS   Zhang D, Penttila TL, Morris PL, Teichmann M and Roeder RG.
  TITLE     Spermiogenesis deficiency in mice lacking the Trf2 gene
  JOURNAL   Science 292 (5519), 1153-1155 (2001)
   PUBMED   11352070
  REMARK    GeneRIF: Role of TRF2 mRNA in male germ cells: In transgenic
            animals deficient in TRF2, spermatid development fails during early
            spermiogenesis with increased apoptosis and failure to develop
            testicular spermatozoa. Infertility phenotype in homozygote males.
REFERENCE   7  (bases 1 to 2880)
  AUTHORS   Martianov I, Fimia GM, Dierich A, Parvinen M, Sassone-Corsi P and
            Davidson I.
  TITLE     Late arrest of spermiogenesis and germ cell apoptosis in mice
            lacking the TBP-like TLF/TRF2 gene
  JOURNAL   Mol Cell 7 (3), 509-515 (2001)
   PUBMED   11463376
REFERENCE   8  (bases 1 to 2880)
  AUTHORS   Berk AJ.
  TITLE     TBP-like factors come into focus
  JOURNAL   Cell 103 (1), 5-8 (2000)
   PUBMED   11051541
  REMARK    Review article
REFERENCE   9  (bases 1 to 2880)
  AUTHORS   Maldonado E.
  TITLE     Transcriptional functions of a new mammalian TATA-binding
            protein-related factor
  JOURNAL   J Biol Chem 274 (19), 12963-12966 (1999)
   PUBMED   10224042
REFERENCE   10 (bases 1 to 2880)
  AUTHORS   Ohbayashi T, Makino Y and Tamura TA.
  TITLE     Identification of a mouse TBP-like protein (TLP) distantly related
            to the drosophila TBP-related factor
  JOURNAL   Nucleic Acids Res 27 (3), 750-755 (1999)
   PUBMED   9889269
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY275848.1, AK049975.1, BE650743.1 and BE995552.1.
            
            [WARNING] On May 19, 2023 this sequence was replaced by
            NM_011603.6.
            
            On Apr 8, 2009 this sequence version replaced NM_011603.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK078547.1, SRR1660819.166027.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-129               BY275848.1         2-130
            130-2249            AK049975.1         2-2121
            2250-2546           BE650743.1         186-482
            2547-2880           BE995552.1         99-432
FEATURES             Location/Qualifiers
     source          1..2880
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10"
     gene            1..2880
                     /gene="Tbpl1"
                     /gene_synonym="4732475G08; STD; TLF; Tlp; TRF2; TRP"
                     /note="TATA box binding protein-like 1"
                     /db_xref="GeneID:237336"
                     /db_xref="MGI:MGI:1339946"
     exon            1..332
                     /gene="Tbpl1"
                     /gene_synonym="4732475G08; STD; TLF; Tlp; TRF2; TRP"
                     /inference="alignment:Splign:2.1.0"
     exon            333..510
                     /gene="Tbpl1"
                     /gene_synonym="4732475G08; STD; TLF; Tlp; TRF2; TRP"
                     /inference="alignment:Splign:2.1.0"
     CDS             376..936
                     /gene="Tbpl1"
                     /gene_synonym="4732475G08; STD; TLF; Tlp; TRF2; TRP"
                     /note="TBP-related factor 2; TATA box-binding protein-like
                     protein 1; TBP-like protein 1; TBP-related protein; 21 kDa
                     TBP-like protein; TATA box-binding protein-related factor
                     2; TATA box binding protein-like protein; TBP-like factor;
                     TBP-like 1"
                     /codon_start=1
                     /product="TATA box-binding protein-like 1"
                     /protein_id="NP_035733.1"
                     /db_xref="CCDS:CCDS23730.1"
                     /db_xref="GeneID:237336"
                     /db_xref="MGI:MGI:1339946"
                     /translation="MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDV
                     GKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKV
                     VNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVT
                     GPNVKAVATAVEQIYPFVFESRKEIL"
     exon            511..593
                     /gene="Tbpl1"
                     /gene_synonym="4732475G08; STD; TLF; Tlp; TRF2; TRP"
                     /inference="alignment:Splign:2.1.0"
     exon            594..657
                     /gene="Tbpl1"
                     /gene_synonym="4732475G08; STD; TLF; Tlp; TRF2; TRP"
                     /inference="alignment:Splign:2.1.0"
     exon            658..761
                     /gene="Tbpl1"
                     /gene_synonym="4732475G08; STD; TLF; Tlp; TRF2; TRP"
                     /inference="alignment:Splign:2.1.0"
     exon            762..856
                     /gene="Tbpl1"
                     /gene_synonym="4732475G08; STD; TLF; Tlp; TRF2; TRP"
                     /inference="alignment:Splign:2.1.0"
     exon            857..2875
                     /gene="Tbpl1"
                     /gene_synonym="4732475G08; STD; TLF; Tlp; TRF2; TRP"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagaaccgga agtgagtggc tagccgggat ccccggagct cctgggtccg gcggcgctct
       61 agccgcctcg tgccgcctct atgcccccgt gcgtctagtc tatttattgt cgcgggggaa
      121 gcggcggccg ccctgtaccc ggaacaacaa agcgagaaac cgagctcgag ccttgggggg
      181 ctcctagcaa cgggcctggg cgggagttcc atggagactg gggagcggac ccgttttatc
      241 ttcatccttg tcctccagct tcttctccgc gtccgacgca accagcagca gcgctgccgc
      301 cgtgtccttt acgaccgccc cgtcttccca cggatgtgat cttcgtggtg ggaaccaagt
      361 ttctaaacta ccccaatgga tgcagacagt gatgttgcat tggacatttt aattacaaat
      421 gtagtctgtg tttttagaac aagatgccat ttgaacttaa ggaagattgc tttggaggga
      481 gcaaatgtaa tttataagcg tgatgttggg aaagtattaa tgaagcttag aaaacctaga
      541 attacagcta caatttggtc ctcaggaaaa attatttgca ctggagcaac aagtgaagaa
      601 gaagctaaat ttggtgccag acgtttagcc cgtagtctgc agaaactagg ttttcaggtc
      661 atcttcacag attttaaggt ggtgaatgtt ttggcagtgt gtaacatgcc ctttgagatc
      721 cgtttgccag aatttacaaa gaacaataga cctcatgcca gctatgaacc tgaacttcat
      781 cctgccgtgt gctatcggat aaagtctcta agagctacat tacagatatt ttcaacagga
      841 agcatcacag tgacagggcc caatgtaaag gctgtggcga ctgccgtgga acagatctac
      901 ccgttcgtgt ttgaaagcag gaaggagatt ttataactca aacttggttg gttagtctcc
      961 acctgagcac cgtttgagac ctgctgcaca ttggactcaa aacacaagga aaactggacc
     1021 aacagtgacc gaggacagac tcggactcac agctgcagtg taagctccag tccctttgga
     1081 ttttacttca aagtttgctg taatataaaa aggaagttta caagacatga cattgctgct
     1141 tttacaaaag gacgttctat ttattttcgc agtaatctcc atgtcccaca ggcagagctg
     1201 tcgcagtgtg cacttcccga cagttgtttt attgatgtca ttatttttcc agttggagct
     1261 aatgtgtttg atttgtgaat agtcttttac atttttgtat gctgaatatg ggcaccaaag
     1321 aacctgtaaa cgttatcttt ttaaattgaa tgtgcacaaa taaaagtttg gaaaagatct
     1381 ctcttcatat ccattctgta acttttattc accatttttt tcttttaaac aactgtattc
     1441 ataatttttt ttaaatctat gcaggcttag actttggcta aagtgtgtgg gcttcttttt
     1501 gaagtgagtt tgtatatatt tgtgtgtatg ctacatgtat atagtatctt ttcatgctct
     1561 gttaccaaat atcaattaga atgttctcct cgcagattgg aagtaaaaac catgtatata
     1621 agctctaggt aactagggta gaactccaca ggtaaatgat aatgtttgtg ttactaattt
     1681 aatatgatag aaaatgttaa atgcgtttga aaagctaaga ggttgtagtt ttgaagagag
     1741 gccttttcct gtctaggtgg atctgcagta gccccgtaac ccttgttatt ctggaaagct
     1801 ggctgtagat gaacgagcca gcagaggttc ttaactaccc ttaggtcggt gctcaaggct
     1861 atgctggtct tgtcagaaat tgactgacat tgtgttttaa caagaagtgg ctcgacttga
     1921 cccaaagcct ctggcaagct ggtctctgtc ctcgccgtgt ctgagtagtg catgtgaagg
     1981 gtgactggag gattaagaga ggccactctt aaacttcagt tccatgagac agggcctcag
     2041 ccgtgcatgg gctctgggtg gaaaggcatg gtcggacagg tgcttagtgt agccaggagt
     2101 ggctttacct accaataaac taggtggagt caaaacttag attctctgta cagacgaaac
     2161 tatttcccac caagctctga cttactgttg tatttttgaa atgtttgcaa aggcttgtga
     2221 catgtgcacc atattacaga ccttccaagg ctaacttaag cactggctgg gcagtgcata
     2281 ggagtctgtg ttcagttctg ttttcttaaa gcctcctcat cccctgcccc tcagctcctt
     2341 cagaacgtgg gagcaaaggt gagctttgca cttgcttttc ccataattca ttgtgacttt
     2401 ttaaagcctt caatttttta aaaattgttt ttatatttgg gttttggttt tttttttttt
     2461 ttttttgctt gttttaagat tatttttaaa aaaccagagg tagaagtaga cggctttaaa
     2521 accgtgagga tttaccactt gttttaacag tgaactcctg gtttgcagtg ttcagaaaca
     2581 tgtatgtgag gcagaaactt gggtagggaa ggtgcagatc cattcgctgt aacatgttca
     2641 gtgttcagtg acctgaaagc caggcagagc tggagctctg ggtaaatgag tgtctaagga
     2701 gggaagagtg agcatggccg agtctggggt cacctgtgag gccactgtct ggcagcttcc
     2761 tgggcagtcc ccacaaaaat gctgggaagg agtgagtggg tgttgcgtcg cctggttttc
     2821 tacaagtact gtaaaatttt ttatataaat aaaaactgtg aatatataca tccaaaaaaa
//
