LOCUS       NM_013763               5588 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus transducin (beta)-like 2 (Tbl2), transcript variant 1,
            mRNA.
ACCESSION   NM_013763
VERSION     NM_013763.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5588)
  AUTHORS   DeSilva,U., Elnitski,L., Idol,J.R., Doyle,J.L., Gan,W.,
            Thomas,J.W., Schwartz,S., Dietrich,N.L., Beckstrom-Sternberg,S.M.,
            McDowell,J.C., Blakesley,R.W., Bouffard,G.G., Thomas,P.J.,
            Touchman,J.W., Miller,W. and Green,E.D.
  TITLE     Generation and comparative analysis of approximately 3.3 Mb of
            mouse genomic sequence orthologous to the region of human
            chromosome 7q11.23 implicated in Williams syndrome
  JOURNAL   Genome Res 12 (1), 3-15 (2002)
   PUBMED   11779826
REFERENCE   2  (bases 1 to 5588)
  AUTHORS   Valero,M.C., de Luis,O., Cruces,J. and Perez Jurado,L.A.
  TITLE     Fine-scale comparative mapping of the human 7q11.23 region and the
            orthologous region on mouse chromosome 5G: the low-copy repeats
            that flank the Williams-Beuren syndrome deletion arose at
            breakpoint sites of an evolutionary inversion(s)
  JOURNAL   Genomics 69 (1), 1-13 (2000)
   PUBMED   11013070
REFERENCE   3  (bases 1 to 5588)
  AUTHORS   de Luis,O., Valero,M.C. and Jurado,L.A.
  TITLE     WBSCR14, a putative transcription factor gene deleted in
            Williams-Beuren syndrome: complete characterisation of the human
            gene and the mouse ortholog
  JOURNAL   Eur J Hum Genet 8 (3), 215-222 (2000)
   PUBMED   10780788
REFERENCE   4  (bases 1 to 5588)
  AUTHORS   Perez Jurado,L.A., Wang,Y.K., Francke,U. and Cruces,J.
  TITLE     TBL2, a novel transducin family member in the WBS deletion:
            characterization of the complete sequence, genomic structure,
            transcriptional variants and the mouse ortholog
  JOURNAL   Cytogenet Cell Genet 86 (3-4), 277-284 (1999)
   PUBMED   10575226
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK132366.1, BC048185.1, AK047090.1, AC024607.3 and BE947541.1.
            
            On May 17, 2018 this sequence version replaced NM_013763.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK132366.1, BC048185.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                AK132366.1         2-26
            26-4361             BC048185.1         1-4336
            4362-4958           AK047090.1         409-1005
            4959-5135           AC024607.3         78710-78886
            5136-5588           BE947541.1         1-453               c
FEATURES             Location/Qualifiers
     source          1..5588
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 75.02 cM"
     gene            1..5588
                     /gene="Tbl2"
                     /gene_synonym="WS-bTRP"
                     /note="transducin (beta)-like 2"
                     /db_xref="GeneID:27368"
                     /db_xref="MGI:MGI:1351652"
     exon            1..179
                     /gene="Tbl2"
                     /gene_synonym="WS-bTRP"
                     /inference="alignment:Splign:2.1.0"
     exon            180..301
                     /gene="Tbl2"
                     /gene_synonym="WS-bTRP"
                     /inference="alignment:Splign:2.1.0"
     exon            302..486
                     /gene="Tbl2"
                     /gene_synonym="WS-bTRP"
                     /inference="alignment:Splign:2.1.0"
     exon            487..638
                     /gene="Tbl2"
                     /gene_synonym="WS-bTRP"
                     /inference="alignment:Splign:2.1.0"
     exon            639..765
                     /gene="Tbl2"
                     /gene_synonym="WS-bTRP"
                     /inference="alignment:Splign:2.1.0"
     exon            766..918
                     /gene="Tbl2"
                     /gene_synonym="WS-bTRP"
                     /inference="alignment:Splign:2.1.0"
     exon            919..5572
                     /gene="Tbl2"
                     /gene_synonym="WS-bTRP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4343..4348
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tbl2"
                     /gene_synonym="WS-bTRP"
                     /note="hexamer: AATAAA"
     polyA_site      4366
                     /gene="Tbl2"
                     /gene_synonym="WS-bTRP"
                     /note="major polyA site"
     regulatory      5546..5551
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tbl2"
                     /gene_synonym="WS-bTRP"
                     /note="hexamer: AATAAA"
     polyA_site      5572
                     /gene="Tbl2"
                     /gene_synonym="WS-bTRP"
ORIGIN      
        1 gagacgtgag gacgccggcg tcgtaggctg aggtggcagc tgtcccgcag tcatggagct
       61 gccgcagatg ccggagctga tggggttgtc cctcctggtg ggtctgctgg ccttggtggc
      121 cacggcggct gtggcgcggg gctggctgcg ggccgaggag aagcccagcc agcccgtctg
      181 tcagaaagaa aacgaaccca agaagtcagg atccaagaag cagaagcaga atcagcgggt
      241 tcgtaaggag aagcctcagc agcacagctt cacgcacccc cttctggctg cagcactgaa
      301 gagccacagt gggaatatat cttgcatgga cttcagcagc aacggcaagt atctggccac
      361 ctgtgcggat gaccgcactg tccgtatctg gagcactaaa gatttccttc agcgggagca
      421 ccgcagcatg agagccaacg tggagctgga ccatgccacc ttggtacgct tcagccctga
      481 ctgcagagcc ttcattgttt ggctggccaa tggggacacc ctccgtgttt ttaagatgac
      541 caagcgggaa gatgggggct ttactttcac ggccacacca gaggatttcc ctaaaaaaca
      601 caaagcgccc atcatcaaca tcggcattgc tgacacaggg aagttcatca tgacggcctc
      661 cagtgacaca actgtcctca tatggaatct gaaaggtcag gtgctttcca cgatcaacac
      721 taaccagatg aacaacagtc acgcagttat ctccccatgt agcaggtttg tgggttcgtg
      781 tggcttcacc ccagatgtga aggtctggga ggtctgtttc gggaagaaag gagagttcca
      841 ggaggtgctg cgagcctttg aactgaaggg tcactctgca tctgtccact ctttcgcttt
      901 ctccaatgac tctcgaagga tggcctccgt ctccaaggat gggacatgga agctatggga
      961 cacagatgtg gagtacaaga agcagcagga cccctacttg ctacggacag gccgctttga
     1021 agaggcgagc accatgcctt gccgcctggc actctcccct gatacccatg tcctggcctt
     1081 ggccactggc accaatattc atctcttcaa cacacgccgc ggggagaagg aggagtactt
     1141 tgagtgtgtc catggggagt gtattgctga cttgactttt gacatcactg gccgcttcct
     1201 ggcctcctgt ggggaccgtg cagtgcggct cttccacaat acccctggcc accgggctgt
     1261 ggtggaggag atgcagagcc tcctgaagcg ggcatccagc gaaagtaccc gccagaggct
     1321 gcagcaacag ctaacccagg cccaagaggc cctcaagagc ctgggtgccc tgaagaagtg
     1381 actctggctc cagatgggtc tggctgtctg gcccagcagc tcctgctccc caggggcccc
     1441 tgggatggag acctggagga aactcccagt tttcttcctg gtgcccccta ctttttccta
     1501 ttgaaactat tcttgcatac tcagatatct ctctctctgt ttctcccttc ttgtttgact
     1561 cttcccagac tgaaagatac tgttttctca caggccctag gggtagaatc tgtcttcatc
     1621 tagcacggag aaggggagta gacagaagac agacagagca aaacctttga tggtttggca
     1681 aaagaccctg acatccaaag aattttgtca gtgtagaggg aaaaccctag ggtcaccagg
     1741 gacaaattgc tgttttataa gagttcagaa cgtgttttat aatgctgcgt ggtgagcctc
     1801 catctggacc aggctcctga tagcagcaag aagtaattaa ggactggtct ttgttggcat
     1861 tggtctgtaa tatcagcact atacaggcaa aggtgagagg atcaggggtt caaggccagc
     1921 ttggactaca tagtgaattc taagtcctcc tgggctccat tcatatggag agaaaccttg
     1981 gcgagattgt ttttccctgg gcttcagttt tcttatttgt aaaatgggga acgatgctct
     2041 ctgtggcctt cctgcaaaga tgctgtgagg ctaggagtgt tataatgctc ccacacatgg
     2101 agcataacag gtctgtccag tgtcattacc taccaggtaa acacaggatg cagacggtgt
     2161 tctgcaagca aactaggaaa aaaccacagc ccttgtgaag ccaagtttcc tagggctctg
     2221 cttgctcatt catcttggat aaacatggtg gtttggttcc cgtgccttga gaagtaatgc
     2281 catcgcaaaa gggtgttcct ctctcaggga cttcttgaac ccatcacttc agggcctgct
     2341 tcatgggacc agctagtgat gctggctaac acagacagac aagactaggc ctgctgccaa
     2401 gggtaaaagc tggtgggagg acctagaggc tggtgtctgt gatgtgcttt ttgttcattt
     2461 acagctgcag gggaggttgt ggacaggagg cttgaccgta gtcaatccag gacaataatg
     2521 gggaaagaat ggaatccacc cactaagaga ctgggtctca gccatgtaca tttgaagact
     2581 gcttggactg gtctttgttg gtgaggaaga tggcaggcat ctaggaaggc ttgaatctag
     2641 caaaaggttc ccatcccagt tagtttttat ctctcttaaa agtagggcct cttcctgcca
     2701 ccctcaatgc tacaggatgt ttataacaag gcacaaccct gaagttgacc ttgatggctc
     2761 ccttgtcacc ctctccttct accactgctg ctacatgcag atggcctgca gcatctgcag
     2821 ctctcccact cttctgttac catcccggtc ttagccactg tcccgtagta tatggatagt
     2881 acctctgttt ccaaccacat tacttcaagt cagttttcta catagtttag cctgctttgg
     2941 gaaaacaaaa atggtatttt ggatcatgcc atttccaaaa ggcttccttc tctctacact
     3001 tggaattaaa ccacaaactc tctttgtggc ctgcgtagtg ttgtgaaatt tagccactcc
     3061 tgtgatcttt ctttgcaatg gtccaatccc attcttccta ttctttgcta acccaggcat
     3121 ttggcaggct ctgggtgtgg gctggtccct cttgtgctgc aagcattttt cctttctgtt
     3181 ggcagacttg tcagtgcgat tcagtccttg taagtttcac tggaaaacag ttgccacctc
     3241 accaactccc tccgaagtag ccatttccac caatcctgtc cctcctggtg ccctgccgct
     3301 tttccttttg tatgaattgg tgctttctga agccatcttg tctggctatg tgtttactgc
     3361 agtgtcagag aagggcagtg agtgggggtt aagagtggga attaggcccg tcacctggtt
     3421 gtgctatgga aggaaacggt agagactgca ctgggctggt ggccgtgtgt cctgggtgca
     3481 cagtgggagg gagccgctac tgactgataa gccgcagaag ttgccagttg cagagaagtt
     3541 agatgctggc actgtacttt gcaaggaggc atccttgtgg actgcaccaa accctgacgg
     3601 gggagggcgc agctcatcag tctcattggt gctgaaggat tcttccttac ttttcctttt
     3661 gcagtcctgg gaatggaagc cagggtcagg tagacaaata gctctgctgg tgagccatgc
     3721 ctcaacccct cactgggaga tgctagacga agactctcct cagccacagc cctagccctc
     3781 actggacaaa tgctttgcct ccaagcctct ttgcagcagt ttgtgaaatt gctgaagaat
     3841 gcgttggaac agaacccttg ttggtctgct ttgctctggg tcccgagtca actagccagg
     3901 acaaagtaag ctctcaataa atgggactct gactagaagt aatgaccaag cttttgatat
     3961 actttgtttt ctgcactccg ctctctattg tggattcagg tttctgataa gatcagccat
     4021 attgaagacc atgtggccac acacggattt gggcttctga ctacacagct gtgcctcagg
     4081 cttgtgtgtg cgtgtggggg tctggtgggc atctgctctg gttgtcggaa agcatctgaa
     4141 aatgcgttct cttgcttctg cactcgtgtc ttgagaagta actggtgccg tggctgcaca
     4201 gggaaggcag tgaaccctag caagaatgct gagctgctga agtcagaagt ctgttcccaa
     4261 actggccaat tcactggcct gtggcctgga gtcctgtaat cacagaggct gccagagttc
     4321 gtctccccac ttgtggaatg ggaataaatg ttgttctgtt accgcgcatg gtgattcttt
     4381 gcttgtgtac atgcttatgg gttacactgg gggttagata tgtgctcttg ccccaaaccc
     4441 attttttttt gtgtgtgtat ttgagaaaaa gactcacttt gttgtcttgg ctggcctgga
     4501 atttatagaa atccacctgt cttggcttcc tgagtgcttg gttttaaggc atgtgccacc
     4561 atacacaggt cctttcgcct gtgttttgag ctaatgtttc actaagttgc ttttgatctt
     4621 gagattctct agcgtgtcag gcctacatct gcatgcctgg gagctgtgag ttctgaatga
     4681 gttgggagca ctacaaaagg tcattgcaca gactgcccag gggtaggcta gagctgttcg
     4741 tgttgcccta ggaaaggtgt ctggctagta ctacaggctg ccaagctttt ctgatcctcg
     4801 agagtagagg cggcattgat ctgctgattc tacacaaggt gtggtagtgc atgcatgcag
     4861 cccaagggct tggcaggttg aagaaccacg agtcagcact gcatagactg tctaaaacac
     4921 agttcatgaa tgtattcatt ttagtttttt gagaaagggt ttctctgtgt agcactggtt
     4981 gtcctggaac ttactctgta caccaggctc gcctcaaact ttacagagat ccacctgcct
     5041 ctgcctctgc ctcccaaggg ctgcgattaa aggcatgtgc caccaccatt cagatctaaa
     5101 acacaaaatt taatactaat tttgaagctt cttaattttt aaaataaagg tatgggtgag
     5161 ctaaaggtgg tgcaaaggtc aaccaactcc aatttcagga ggaaaaccgc aaagtccact
     5221 tgagcaaaca tctgatggca atagcccccc atcctccacc cctcttaaca acagccagtt
     5281 agtctacagc agcatggtca aggtacatat aaactaagac atctggcaga aaaaagataa
     5341 cccagccatc ctatttgtca ggtggttttg cccctgtgtt tggttcctgc aaattacagc
     5401 agaaatgcag ttttaaaaat attaatttgc tgacctgtat ggaattcccc aagcttgctg
     5461 taaccaccat aaataccctg cacccctaga ctcgaggctc tcacttctga ccactgcacc
     5521 ggtgatggag tgctcttgag ctcctaataa aagcccatat gtgtttacat caaaaaaaaa
     5581 aaaaaaaa
//
