LOCUS       NM_001290760            5271 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus TBC1 domain family, member 9B (Tbc1d9b), transcript
            variant 1, mRNA.
ACCESSION   NM_001290760 XM_006534457
VERSION     NM_001290760.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5271)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5271)
  AUTHORS   Nishino,H., Saito,T., Wei,R., Takano,T., Tsutsumi,K., Taniguchi,M.,
            Ando,K., Tomomura,M., Fukuda,M. and Hisanaga,S.I.
  TITLE     The LMTK1-TBC1D9B-Rab11A Cascade Regulates Dendritic Spine
            Formation via Endosome Trafficking
  JOURNAL   J Neurosci 39 (48), 9491-9502 (2019)
   PUBMED   31628178
REFERENCE   3  (bases 1 to 5271)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY207144.1, AK049999.1 and BC065130.1.
            
            On Mar 19, 2014 this sequence version replaced XM_006534457.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                BY207144.1         1-42
            43-3027             AK049999.1         3-2987
            3028-5271           BC065130.1         2920-5163
FEATURES             Location/Qualifiers
     source          1..5271
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 30.28 cM"
     gene            1..5271
                     /gene="Tbc1d9b"
                     /note="TBC1 domain family, member 9B"
                     /db_xref="GeneID:76795"
                     /db_xref="MGI:MGI:1924045"
     exon            1..197
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     CDS             80..3871
                     /gene="Tbc1d9b"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="TBC1 domain family member 9B isoform 1"
                     /protein_id="NP_001277689.1"
                     /db_xref="CCDS:CCDS70175.1"
                     /db_xref="GeneID:76795"
                     /db_xref="MGI:MGI:1924045"
                     /translation="MWLGPEEVLVANALWVTERANPFFVLQRRRGHGKGGGLTGLLVG
                     TLDVVLDSSARVAPYRILHQTQDSQVYWIVACGSSRKEITKHWEWLENNLLQTLSIFD
                     NEEDITTFVKGKIHGIIAEENKNLQPQGDEDPGKFKEAELKMRKQFGMPEGEKLVNYY
                     SCNFWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSLVVQWVDVTRLEKNATLLFPESIR
                     VDTRDQELFFSMFLNIGETFKLMEQLANLAMRQLLDSEGFLEDKALPRPIRPHKNISA
                     LKRDLDARAKNECYRATFRLPKDERLDGHTGCTLWTPFNKLHIPGQMFISNNYICFAS
                     KEEDACRLIIPLREVTIVEKADSSSVLPSPLSISTKSKMTFLFANLKDRDFLVQRISD
                     FLQKTPSKQTGSSIGGTKASVSDPAPESLPTPQEASEPPASPSSPLSSPPSFSTQEIP
                     TTSQGLLKVFQKNSPMEDLGAKGAKEKMKEESWNIHFFEYGRGMCMYRTAKTRELVLK
                     GIPESLRGELWLLFSGAWNEMVTHPGYYAELVEKSLGKYSLATEEIERDLHRSMPEHP
                     AFQNELGIAALRRVLTAYAFRNPTIGYCQAMNIVTSVLLLYGSEEEAFWLLVALCERM
                     LPDYYNTRVVGALVDQGIFEELTRDVLPRLSEKMQELGVISSISLSWFLTLFLSVMPF
                     ESAVVIVDCFFYEGIKVILQVALAVLDANVEQLLDCNDEGEAMTVLGRYLDNVVNKQS
                     ISPPIPHLHALLTSGDDPPVEVDIFDLLRVSYEKFSNLRADDIEQMRFKQRLKVIQSL
                     EDTAKRSVVRAIPGDIGFSIEELEDLYMVFKAKHLASQYWGGNRSAAVHRDPSLPYLE
                     QYRIDASQFRELFASLTPWACGSHTPVLAGRMFRLLDQNKDSLINFKEFVTGMSGMYH
                     GDLTEKLKALYKLHLPPALIPEEAESALEAAHYFTEDSSSEASPLASDLDLFLPWEAQ
                     ALLQEQQEGSGNEDTPERREEKGTSPPDYRHYLRMWAKEKEAQKETIKDLPKMNQEQF
                     IELCKTLYNMFSEDPMEQDLYHAIATVASLLLRIGEVGKKFSALTTKKPRDGAHSGDP
                     NSATEEDEPPTPKLHQDPTQECQPPAAGDRQAKASGDMHLGKALQDSHVIVEGGSGEG
                     QGSPSLLLSDDETKDDMSMSSYSVVSTGSLQCEDLTEDTVLVGGGACSPTATSRAGGT
                     VDTDWCISFEQILASILTESVLVNFFEKRVDIGLKIKDQKKVERQFSTSSDHEPPGVL
                     G"
     exon            198..308
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            309..427
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            428..656
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            657..915
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            916..1123
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            1124..1336
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            1337..1498
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            1499..1649
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            1650..1864
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            1865..1982
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            1983..2268
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2269..2398
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2399..2497
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2498..2566
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2567..2807
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2808..2873
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2874..2945
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2946..2996
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2997..3053
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            3054..3160
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     exon            3161..5249
                     /gene="Tbc1d9b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4470..4475
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tbc1d9b"
                     /note="hexamer: AATAAA"
     polyA_site      4494
                     /gene="Tbc1d9b"
                     /note="major polyA site"
     regulatory      5227..5232
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tbc1d9b"
                     /note="hexamer: AATAAA"
     polyA_site      5249
                     /gene="Tbc1d9b"
ORIGIN      
        1 tctcggctcg gctcgggcgc ggcgacggcg gcgcgcgctt ccgcctcacg ggctctggcc
       61 cggtgcgagc ggccgcggga tgtggctcgg gcccgaggag gtgctggtgg ctaacgcgct
      121 atgggtgacg gagcgggcca accccttctt cgtgctgcag cggcgccgag gccacggcaa
      181 gggcggaggc ctcacgggtc ttcttgtggg caccctggat gtggtgctgg actccagcgc
      241 ccgtgtggcc ccttaccgca tcctgcacca gacccaggac tcgcaggtct actggatagt
      301 ggcatgtggt tcttcccgaa aagagatcac caaacactgg gaatggctgg aaaacaactt
      361 gcttcagaca ctgtccatct tcgacaacga ggaggacatc actaccttcg tcaagggcaa
      421 gatacacggc atcatcgcag aagagaacaa gaacctgcag ccccaggggg acgaggaccc
      481 agggaaattc aaggaggcag agctaaagat gcggaagcag ttcggcatgc cagagggcga
      541 gaagctggtc aactactact cctgtaactt ctggaagggc cgcgtgccgc gccagggctg
      601 gctctacctg accgtcaacc acctgtgctt ctactccttc ctgctgggga aggaagtgag
      661 cctggtggta cagtgggtgg acgtcacacg cctggagaag aatgccactt tactcttccc
      721 cgagagcatc cgtgtggaca cacgggacca ggagctgttt ttctccatgt tcctaaacat
      781 tggcgagacc ttcaagctta tggagcagct ggccaacctg gccatgcgac aactgctgga
      841 cagcgagggc ttcctggagg acaaggccct acccaggcct atccggccac ataagaacat
      901 ctcagctcta aagcgagacc tagatgcccg agccaagaat gagtgctaca gggccacgtt
      961 ccggctaccc aaagacgagc ggctggatgg ccacacaggc tgcaccctat ggacgccatt
     1021 taacaagcta catatccccg gccagatgtt catctccaat aactacatct gctttgccag
     1081 caaggaggaa gatgcgtgcc gcctcatcat acccctgagg gaggtgacca ttgttgaaaa
     1141 agccgacagc tccagcgtcc tccccagccc tctgtctatc agcaccaaga gtaaaatgac
     1201 cttcctgttt gccaacctga aagaccgtga cttcctggtt cagaggatct ctgacttcct
     1261 ccagaaaacg ccgtccaagc agacgggcag cagcattggg ggaacaaagg ccagtgtttc
     1321 agacccagcc ccagagtctc tcccaactcc acaggaggct tctgagccac ccgcaagccc
     1381 atcctctccc ctcagcagcc ctccgagttt cagtacccag gagattccta ctacttccca
     1441 gggcctgctc aaagtcttcc agaagaactc acccatggag gaccttggcg ccaaaggggc
     1501 caaggagaag atgaaggagg aatcctggaa catccacttc tttgagtacg ggcgtggcat
     1561 gtgcatgtac cgaacagcca aaacccggga gctggtcctg aaaggcatcc ctgagagcct
     1621 ccgaggggag ctttggctcc tcttctctgg ggcctggaat gagatggtga cccatcccgg
     1681 ctactacgct gagctagtgg agaagtccct ggggaagtac agcttggcta ccgaggagat
     1741 agagcgggac ctccatcgct ccatgcccga gcaccctgct ttccagaatg agctcgggat
     1801 cgctgcgctc cggcgggtgc tgactgccta cgccttccga aaccctacta ttggctactg
     1861 ccaggcaatg aacatcgtga cttccgtgct cctgctctac ggcagtgagg aggaagcctt
     1921 ctggctgctg gtggccctgt gtgagcgcat gctgcccgac tactacaaca ccagggtagt
     1981 gggagccctc gtagaccagg gcatctttga agagctcacg agagatgtcc tgccccggct
     2041 ctcagagaag atgcaagagc tgggggtgat ctccagcatc tcgctgtcct ggttcctgac
     2101 cctcttcctc agcgtcatgc cctttgagag cgccgtggtc attgtcgact gcttcttcta
     2161 cgagggcatc aaggtgatcc tgcaggtggc cctggctgtg ctggacgcca acgtggagca
     2221 gctgctggac tgcaatgacg agggcgaggc catgaccgtg ctgggcaggt acctggacaa
     2281 tgtggtcaac aagcagagca tttctccacc tatcccacac ctccacgctc tgctgaccag
     2341 tggagatgac cctcctgtgg aggtggacat ctttgacctc ctgagagtat cctacgagaa
     2401 gttcagcaac ctgagggctg acgacattga acagatgcgg tttaaacaga ggctgaaggt
     2461 gatccagtcc ttggaagaca cggctaagag aagcgtggtc cgagccatac caggggacat
     2521 cggcttctcc attgaagagc tggaggatct ttacatggtg tttaaggcca agcatctggc
     2581 aagccagtac tggggtggta accgctcagc agccgtccac cgagacccca gcctgcccta
     2641 cctggagcag taccggatcg atgccagcca gtttcgggag ctctttgcca gcctgacgcc
     2701 ttgggcctgt ggctctcaca cgcctgtgtt ggcaggccgc atgttccgac tcctggatca
     2761 aaacaaggac tcactgatca acttcaagga gtttgtgaca gggatgagtg ggatgtacca
     2821 tggagacctc actgagaagc tcaaggcgct ctacaaactg cacctgcccc cagctctgat
     2881 cccagaggaa gccgagtcag ccctggaggc cgcccattac ttcacagagg atagctcctc
     2941 ggaagcatct cctctggcct cagatctgga tcttttcctg ccctgggagg ctcaagcact
     3001 gctacaggag cagcaggaag gaagtggaaa tgaggacacc ccagaaagaa gagaggagaa
     3061 ggggaccagc cctcctgact accgacacta ccttcgaatg tgggctaagg aaaaagaggc
     3121 tcagaaggaa accattaagg accttcccaa gatgaaccag gagcaattca tcgagctgtg
     3181 taaaacactt tacaacatgt ttagcgaaga ccctatggaa caggacttgt atcatgccat
     3241 cgccactgtg gccagccttc tcctccgcat tggtgaggtg gggaagaagt tttcggccct
     3301 gacaaccaag aagcccaggg atggtgccca cagtggggat cccaacagtg ccacagaaga
     3361 ggatgaacca cccacaccca aactccatca ggacccaaca caggaatgtc agccaccagc
     3421 tgcaggggac cggcaggcca aagccagtgg cgacatgcat ctcgggaaag cattgcagga
     3481 tagtcatgtg atagtggagg gaggcagcgg tgaggggcag ggctctcctt ccctgctttt
     3541 gtctgatgat gaaaccaaag atgacatgtc catgtcctct tactcagtag tcagcacggg
     3601 ctcactgcag tgcgaggacc tcacggaaga cacggtgctg gtgggaggag gagcctgcag
     3661 ccccaccgcc acctcacggg cggggggcac tgtggacaca gactggtgca tttccttcga
     3721 gcagatcctg gcctccatcc taacagagtc tgtgctagtg aacttctttg agaagagggt
     3781 agacattgga ctcaagatca aggaccaaaa gaaagtagaa aggcagttta gcacctccag
     3841 tgaccatgag ccccctgggg tcttgggctg aactgtgaaa tggaaggcag tctctgtctc
     3901 cttccttctc cctcgctgtt ttctcctcac agacacacct gttcttggag cagggtgtca
     3961 cagaagcaaa ggaggtcagg tccacgcaga cccagttgcc ttacagggat tccctaggcc
     4021 agggcaacct cttcctccct gctcttggtt acctggagga cctgctttga gcctcctgtt
     4081 cccatagcat tagaggcttt tggatctgcc cctgcctgct tcttgcccct gcaccctgtg
     4141 ctgtgcacac actacactgg ttgcaccatc tatggaaaga cctacagcca tgtggcctgg
     4201 ccaccaattg tcactttgcc atgtgcttgg gccccaaagg atgcaacctt ctagacaccc
     4261 tctgaagttc ttcagcctga acctgcgtct taggactgag gaacgcaggg gaatgtctgt
     4321 cgcatgggta ggagccttgc actgcacacc caacttacga ggactccatt cctctgcatc
     4381 attaacttgg aaagtgcacc cctcaggtcc tcctctagaa ccctgccctc attttagttg
     4441 gctaaaaacc acactgtgct caatgcctta ataaatccct gaaagaaaga aaaagcacac
     4501 tgtgtgcagt gcttttcctg tggctttcag tctgtgtatg ctttcttccc aagtcaggta
     4561 tatggcccag aaagcattgt ggggagttca gttcacttgg ctgcctgtag taggtgaggg
     4621 gattgctaga ctttccatgg tacacagtaa ctgtagtcac aggtcttagg ctcagtgtcc
     4681 aaagatgtat gaatatagta gatacatcct caggcctgag tcacaccaag ttgtcagccc
     4741 tttggttcag gaagcagaca tggccagagc aggactcagc catgagttag ccctggctgt
     4801 ttagcaggac agaggcatcc atgtgcccaa gagctgcttt tgcttctacc aacaaatgga
     4861 tcctgataaa gccaagtgcg gtgggtggca tgtctataat cctgcccttg aggatgaagt
     4921 aagacaattg tgttgtttga ggccaaccct aagctacatg tggagatcct gtctcaaaaa
     4981 gctaaaataa ataagaagac attaggtatt atttacaaca atactttaaa ctttgctgat
     5041 tcccagcacg aatgtaaaag ctgggcatgg tcatgcccac ctgtgcccca gtgctggtga
     5101 tcagagatgg gcagcctaac cagatagcca gcttcaggtt cagtgagaaa ccctgcctca
     5161 agggaataac gcagagcgat gaaatgggac atgctggtct ctgcccacac caccacacaa
     5221 atactaaata aaaaattttt taaaaattaa aaaaaaaaaa aaaaaaaaaa a
//
