LOCUS       NM_173186               7796 bp    mRNA    linear   ROD 04-FEB-2025
DEFINITION  Mus musculus TBC1 domain family, member 24 (Tbc1d24), transcript
            variant 4, mRNA.
ACCESSION   NM_173186
VERSION     NM_173186.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7796)
  AUTHORS   Pepe,S., Aprile,D., Castroflorio,E., Marte,A., Giubbolini,S.,
            Hopestone,S., Parsons,A., Soares,T., Benfenati,F., Oliver,P.L. and
            Fassio,A.
  TITLE     TBC1D24 interacts with the v-ATPase and regulates intraorganellar
            pH in neurons
  JOURNAL   iScience 28 (1), 111515 (2024)
   PUBMED   39758816
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7796)
  AUTHORS   Defourny,J.
  TITLE     TBC1D24 is likely to regulate vesicle trafficking in glia-like
            non-sensory epithelial cells of the cochlea
  JOURNAL   Int J Dev Biol 68 (2), 79-83 (2024)
   PUBMED   38869222
  REMARK    GeneRIF: TBC1D24 is likely to regulate vesicle trafficking in
            glia-like non-sensory epithelial cells of the cochlea.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7796)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 7796)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7796)
  AUTHORS   Morimune,T., Tano,A., Tanaka,Y., Yukiue,H., Yamamoto,T.,
            Tooyama,I., Maruo,Y., Nishimura,M. and Mori,M.
  TITLE     Gm14230 controls Tbc1d24 cytoophidia and neuronal cellular
            juvenescence
  JOURNAL   PLoS One 16 (4), e0248517 (2021)
   PUBMED   33886577
  REMARK    GeneRIF: Gm14230 controls Tbc1d24 cytoophidia and neuronal cellular
            juvenescence.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7796)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   7  (bases 1 to 7796)
  AUTHORS   Corbett,M.A., Bahlo,M., Jolly,L., Afawi,Z., Gardner,A.E.,
            Oliver,K.L., Tan,S., Coffey,A., Mulley,J.C., Dibbens,L.M.,
            Simri,W., Shalata,A., Kivity,S., Jackson,G.D., Berkovic,S.F. and
            Gecz,J.
  TITLE     A focal epilepsy and intellectual disability syndrome is due to a
            mutation in TBC1D24
  JOURNAL   Am J Hum Genet 87 (3), 371-375 (2010)
   PUBMED   20797691
  REMARK    GeneRIF: A pathogenic mutation was identified in TBC1D24.
REFERENCE   8  (bases 1 to 7796)
  AUTHORS   Falace,A., Filipello,F., La Padula,V., Vanni,N., Madia,F., De
            Pietri Tonelli,D., de Falco,F.A., Striano,P., Dagna Bricarelli,F.,
            Minetti,C., Benfenati,F., Fassio,A. and Zara,F.
  TITLE     TBC1D24, an ARF6-interacting protein, is mutated in familial
            infantile myoclonic epilepsy
  JOURNAL   Am J Hum Genet 87 (3), 365-370 (2010)
   PUBMED   20727515
  REMARK    GeneRIF: Two compound heterozygous missense mutations (D147H and
            A509V) in TBC1D24, a gene of unknown function, are responsible for
            familial infantile myoclonic epilepsy.
REFERENCE   9  (bases 1 to 7796)
  AUTHORS   Hughes,D.S., Keynes,R.J. and Tannahill,D.
  TITLE     Extensive molecular differences between anterior- and
            posterior-half-sclerotomes underlie somite polarity and spinal
            nerve segmentation
  JOURNAL   BMC Dev Biol 9, 30 (2009)
   PUBMED   19463158
  REMARK    Publication Status: Online-Only
REFERENCE   10 (bases 1 to 7796)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC117577.16, AK084693.1, CT010502.14 and AI661779.1.
            
            On Aug 6, 2009 this sequence version replaced NM_173186.3.
            
            Transcript Variant: This variant (4) uses an alternate splice site
            in the 5' UTR, and lacks an alternate in-frame exon in the central
            coding region, compared to variant 1. The resulting isoform (b) is
            shorter than isoform a. Variants 4-8 encode the same isoform.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK084693.1, SRR9219382.230996.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-47                AC117577.16        147084-147130
            48-1240             AK084693.1         2-1194
            1241-1241           CT010502.14        4299-4299
            1242-4441           AK084693.1         1196-4395
            4442-7402           CT010502.14        10760-13720
            7403-7796           AI661779.1         1-394               c
FEATURES             Location/Qualifiers
     source          1..7796
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.3 cM"
     gene            1..7796
                     /gene="Tbc1d24"
                     /gene_synonym="9630033P11; C530046L02Rik; mKIAA1171"
                     /note="TBC1 domain family, member 24"
                     /db_xref="GeneID:224617"
                     /db_xref="MGI:MGI:2443456"
     exon            1..89
                     /gene="Tbc1d24"
                     /gene_synonym="9630033P11; C530046L02Rik; mKIAA1171"
                     /inference="alignment:Splign:2.1.0"
     exon            90..199
                     /gene="Tbc1d24"
                     /gene_synonym="9630033P11; C530046L02Rik; mKIAA1171"
                     /inference="alignment:Splign:2.1.0"
     exon            200..1283
                     /gene="Tbc1d24"
                     /gene_synonym="9630033P11; C530046L02Rik; mKIAA1171"
                     /inference="alignment:Splign:2.1.0"
     CDS             319..1986
                     /gene="Tbc1d24"
                     /gene_synonym="9630033P11; C530046L02Rik; mKIAA1171"
                     /note="isoform b is encoded by transcript variant 4"
                     /codon_start=1
                     /product="TBC1 domain family member 24 isoform b"
                     /protein_id="NP_775278.3"
                     /db_xref="CCDS:CCDS28477.1"
                     /db_xref="GeneID:224617"
                     /db_xref="MGI:MGI:2443456"
                     /translation="MDPPGYNCFVDKDKMDASIQDLGPKELNCTELQELKQLARQGYW
                     AQSHTLRGKVYQRLIRDIPCRTVTPDASVYSDIVGKIVGKHSSSSLPLPEFVDNTQVP
                     TYCLNTRGEGAVRKILLCIANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILS
                     CNDPTKKLIDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSEDVLQVYSDWQRWLFG
                     ELPLNYFARVFDVFLVEGYKVLYRVALAILKFFHKVRAGQPLESDNVKQDIRMFVKDI
                     AKTVSPEKLLEKAFAIRLFSRKEIQLLQMANEKALRQKGITVKQKRQFVHLAVHAENF
                     HSEIVSVKEMRDIWSWIPERFALCQPLLLFSSLQHGYSLSRFYFQCEGHEPTLLLIKT
                     TQKEVCGAYLSTDWSERTKFGGKLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKAT
                     SLKSSEAAGSSSLISHCSSDPADRLSPFLAARHFNLPSKTESMFMAGGNDCLIIGGGG
                     GQALYVDGDLNRGRTGHCDTFNNQPLCSENFLIAAVEAWGFQDPDTE"
     exon            1284..1442
                     /gene="Tbc1d24"
                     /gene_synonym="9630033P11; C530046L02Rik; mKIAA1171"
                     /inference="alignment:Splign:2.1.0"
     exon            1443..1506
                     /gene="Tbc1d24"
                     /gene_synonym="9630033P11; C530046L02Rik; mKIAA1171"
                     /inference="alignment:Splign:2.1.0"
     exon            1507..1602
                     /gene="Tbc1d24"
                     /gene_synonym="9630033P11; C530046L02Rik; mKIAA1171"
                     /inference="alignment:Splign:2.1.0"
     exon            1603..1831
                     /gene="Tbc1d24"
                     /gene_synonym="9630033P11; C530046L02Rik; mKIAA1171"
                     /inference="alignment:Splign:2.1.0"
     exon            1832..7796
                     /gene="Tbc1d24"
                     /gene_synonym="9630033P11; C530046L02Rik; mKIAA1171"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5017..5022
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tbc1d24"
                     /gene_synonym="9630033P11; C530046L02Rik; mKIAA1171"
                     /note="hexamer: ACTAAA"
     polyA_site      5034
                     /gene="Tbc1d24"
                     /gene_synonym="9630033P11; C530046L02Rik; mKIAA1171"
                     /note="major polyA site"
     regulatory      7769..7774
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tbc1d24"
                     /gene_synonym="9630033P11; C530046L02Rik; mKIAA1171"
                     /note="hexamer: AATAAA"
     polyA_site      7796
                     /gene="Tbc1d24"
                     /gene_synonym="9630033P11; C530046L02Rik; mKIAA1171"
                     /note="major polyA site"
ORIGIN      
        1 gtggggcggg gccgcctacg cgcgtgcgca gaaagtccag tgcggtccag cggagagccg
       61 aagggagagg tgcggtgcgg cgcgccgagt tgaactttct agatgcaaga gaaatcagag
      121 tggtgtgaat atttaccgca agtcactgaa gtggacccct gtgacattgt tggacagttc
      181 taccatccag atcagaaagg gtgtgtggga tgacagactg gttaacagaa aacccccgaa
      241 gctggggctg caggatttag ctgctttttg ttcccttcct ggcagcctag gacctgcctt
      301 gtgggcacac tgggcaccat ggacccccca gggtacaatt gctttgtgga taaggacaag
      361 atggatgcat ccatccagga cctggggcca aaggagctga actgcacgga gctacaggag
      421 ctgaagcaac tggcacggca gggttactgg gctcagagcc acaccctgcg cgggaaagtg
      481 taccagcgcc tgatccggga catcccctgc cgcacagtca cacctgatgc cagcgtgtac
      541 agtgacattg tggggaagat tgtgggcaag cacagcagca gtagtctgcc cttgcctgag
      601 tttgtagaca acactcaggt gcccacctac tgcctgaaca cacggggtga aggggctgtg
      661 cgcaagatcc tcctgtgtat tgccaaccag ttccctgaca tctccttctg ccctgccctg
      721 cctgctgtgg tggccttgct actgcactac agcatcgatg aagctgagtg tttcgaaaaa
      781 gcctgccgca tcttatcctg caatgacccc accaagaagc tcattgacca gagcttcctg
      841 gcctttgagt cttcctgtat gacatttggg gacctggtga acaagtactg ccaggcagcc
      901 cataaactga tggtggccgt gtcagaggac gtcctgcagg tctactctga ctggcagcga
      961 tggctctttg gggagctgcc cctcaattac tttgcccgtg tttttgatgt cttccttgta
     1021 gaaggctaca aagtattgta ccgagttgct ctggccatcc tcaagttctt ccacaaggtg
     1081 agagcaggac agccccttga gtcagacaat gtaaagcaag acatccgaat gtttgtcaag
     1141 gacattgcca agacagtgtc ccctgagaaa ctactagaga aggcctttgc catccgccta
     1201 ttttcccgaa aggagatcca gctcttgcaa atggccaatg agaaagcact gaggcagaag
     1261 ggtataactg tcaaacagaa gaggcagttt gtgcacttag ctgtccatgc agagaacttc
     1321 cactcagaga ttgtcagcgt gaaggagatg agagacattt ggtcctggat ccctgagcgc
     1381 tttgccctct gccaacccct cctgctcttc tcatcactgc agcatgggta cagcctaagc
     1441 aggttctatt tccagtgtga aggacatgag cccaccctcc tgctcatcaa gaccactcaa
     1501 aaggaggtct gtggggctta cctgtcaaca gactggagcg agaggactaa attcggaggc
     1561 aagctgggct tctttgggac tggagaatgc tttgttttta ggctgcagcc ggaagtgcag
     1621 cgctatgagt gggtggtcat caaacaccca gagctgacca aggcaacatc cctcaagtct
     1681 tcagaggctg caggcagttc ttccctcatc agccactgct cttcagaccc cgctgatcgg
     1741 ctctcccctt tcctggctgc ccggcacttc aacctgccct ccaagactga gtccatgttc
     1801 atggctggag gcaatgactg cctcatcatt gggggaggag gtggtcaagc actctacgtt
     1861 gatggggacc tgaatcgagg gcgcactgga cactgtgaca cattcaacaa ccagcccctc
     1921 tgctctgaga acttcctcat cgcagctgtg gaggcttggg gcttccaaga ccctgacacc
     1981 gaatgacggg cccgcactga tggtgacagc cacattgtgg ggtgatggga cagaggcccg
     2041 gctgcctctt cagggagcag ggagtgagtg agacgtcacc cccagaaagt ggaaaggttt
     2101 gctgtgcagt ggggctgtta gtctctcacg ccaggcctgg ccctggcttg gacttaggtt
     2161 aggattcctg agccctcctg cttctgagct cttgaaccct cagccctgtc tagcatctct
     2221 gtaagagaca ccctctgccc tcacccaggg ccctggctct gccaggtgtc ctgtacccac
     2281 aattgccaag gctacatttc catgcccctg agcctcagcc ccttataaga aaagggcaaa
     2341 tgaatcttct tgccaaatgt gggcccatgg tgcccccctg ctggtgcttt gaccctgcag
     2401 ctcctctgag gttcccctca gaggggtaca tttgctgctg tagtgtaggg taggattggg
     2461 aagggcaggg tctgtgagtt ctgcagctcc ccctagtcta gagatggaat gagggctgga
     2521 gaactgtctt ttgtctttgt gtttctgcag agcctgaagc tcttgctgcg cctcgctgcg
     2581 agtccacacc tgaaggtggc ctccggagag actttctttg accaccttgg ccagtcagct
     2641 ccatttccag agttcttctc agagctgact agactctgag gcctttgcct ctcatccctg
     2701 tggcctcctt gaagttctgt agtcttggtg actcttgtac ttggttcctc tgtcacagtg
     2761 actgaggccc accaagcatg gcatgcttgt ccccatccag ctttttgcct tctccccagg
     2821 ccctgtgctc ccctggaccc gttcacacag catctgattc acctgtgtga cctgatccct
     2881 cagctggcac tgtggccgac cacgtactgt atcttctgtg tgctacccct gcccctatta
     2941 aggccttcag gtctctggat gtctgtgctt cctgagccct gtgccagcct gtgcacatag
     3001 gatgccagcc tgtgcacata ggatgccagc ctgtgcacat aggatgccag cctgtacaca
     3061 taggatgcca gcctgtgcac ataggatgcc agcctgtgca cataggatgc cagcctgtgc
     3121 acataggatg ccagcctgtg cacataggat gccagcctgt gcacatagga tgccaaggga
     3181 ggtgctgctt ctgaggactc tcgcaagctc ctcttccccg tgacctccct cagctggtcc
     3241 tgagggtcta ggcgccacag aggaagagag aagaagcagt ggcccaaatg gctctgctgg
     3301 ggccatggaa gtcgggatca taaggacagg cgcctagctt ccacatgact gtctggcgtg
     3361 cttgagagtc agcatgtgtc aggccagtgc ttgtctccac gctgagattc actttcgctg
     3421 gggaaggtcc atccttccct gttccaccaa ttcacaccag ctctctgcac ggccacagtg
     3481 gcagaagagg cagggcagaa aggagcctca tgcatctaga actctggatt ctgcacagtg
     3541 gacaagttcc cccaccatgc tggcttccag gatgggttcg cgtgactcta tagagtgaag
     3601 aggaaccact gttgctcacc tctacagaag gttataagcc tcaatgccca cttcccctga
     3661 gcccactgcc gaggcctaga cctccaactc tggtgttcat ttaacaccat cttgattttt
     3721 gtttctggca agatcttact agttaaccta actggcctgg aactccctat gtagcccagg
     3781 ctagcctgga aattgctatg tagcctaggt tagactcaaa aatcatgatc tccctcagcc
     3841 tcctcattgc tgggcttcta ggtgttaggc ccagctgagc gctttgagtt tgactgcctc
     3901 cgttctgagt cgggctcctg ccagaaggcc cccaggacgt tcccaggctg agctcttgcc
     3961 gctcacccat gcattaccac tgagactcag aagccttcag aagcaatgac gttaattggg
     4021 agtatgtgcg gggctctgca gggttccaga ctggtggtgg accttgtgtt ctgtgtggcc
     4081 cccactggca gtcccagggg tctagcccaa ggagactgat ggatgctgag tcatgatcac
     4141 atcacaagca aagttcttag cttttctccc acaacatacc cagctcttta aatttaatgt
     4201 cctttttttt tctgactttt ctaccaaaag gtgtgtattg ttttctttat atttttattc
     4261 ttatcactgt tcttatctga tactactaag tgttctcact tagtatttat tttattaatg
     4321 ttttctatta tttattagct tttgatgtta aaaaaaaacc aagccaaaat gtgatggcat
     4381 tgtataagaa gttatatttt agcagcattc aaacatttgt ttttaaaaca aatacttaat
     4441 ccaatttaag cccattcgtt aaactaacca agtttgttaa tatatagcat atgccgtcgg
     4501 agcctcagaa gctcagttta tgatttgctt tggtttagtt tgtgacaaga gtgtcagttt
     4561 catgcagctc aggctagcct tgaactaact gtgtagctga agctgccctt ggattcatct
     4621 tcctgctttc atcctctaca tatttgcatt acaggtgtgt gtgtgtgcca ccatgcctgg
     4681 tgataatcag ctcattttta aagtaattta tgatacaaca ctaggtgttg gcattttaag
     4741 aatatatata tatgtatgca tatatgtata catatgatat gtatatatat atgtatgcat
     4801 atatgtatac atatgatata tatacatata tacatataca tatatatata tattggtttt
     4861 tggttttcaa gacagggttt ctctgtgtag ctctggctat cctggaacag aatctataga
     4921 ctaggctggc ctctgactca cagatgcatc tgcctcctga gtgctgggat taaaggtatg
     4981 tgccaccacc gtccatccta atttctctat tattaaacta aaattactat ttaatttttc
     5041 ctatttttta taagctgtct gcttttattt tccagttttt cagtgcagtt tgttttagag
     5101 cattctggat ttcagatctt taaatgtcct ttacccattt tctgagttcg tagaggtttt
     5161 ctgatctctt taaatatttt atatttgaca atttaggttt tgtgccccct ccctttgaga
     5221 tgctgaggat tgaacctaag accttataca ttctaggcaa gttctctacc actgagccat
     5281 gccctcagcc ctacatttat atattgaact gattttcagt ttacatcaga attgctgaga
     5341 tggaatttat agactctcat ccacttgtct actataaaca tcaaaaaaca attggcctag
     5401 tggcagactc ttaatcccat tattcagaag gtagaggtag ggggatctca gagagtttga
     5461 ggccatcctg ttctatgtaa caggttccag accagccagg gctacataat aagaccttgt
     5521 cttaaaaata tatatgtata tgtgtatata cacatacata catacataca tacatacata
     5581 catacataca tacatacata catgggctgg ggataaagag aaggctcagt aattagagca
     5641 ctgggccttc cagggtaccc aagttcagtt ttcagtatct atatgatggc ttacaactat
     5701 ctataactca gttcctaggg atctaagccc tttcttggct tctgtaggca ctgtgccaat
     5761 gtagaacaca gacacagtca aaacactcat aaacataaaa taaaaatgaa gggaaagata
     5821 aaacagacat tattgtggtg cagtgcccct gactgtacag gaatacatgc agttttacag
     5881 agacctgctc tctcatatct tcactaaatc tagaaagtta cagattgtac tagttgtttt
     5941 gtttttaagt cactattgag gttgaagttc tgtagcaact acctcagaga gggctagctc
     6001 ctccatagct ctattcaggt ctgtgtgaca aagttgttat gtcaagcatg agtgccaaac
     6061 aggctttaca cttctttccc cacagtattt ccatcaggct ggaaagcata tgaagtgtaa
     6121 aggataattt tggtattaag attcgtatct gggcctggtg tgtgtctata atcccagcac
     6181 atggacggta gaggcagaaa tgtcaaatca tctttagcaa cagaacaagt tcaagctagc
     6241 tatggctaca agagacctgt ctcaataaac aaacaaacag acaaataaat ggagtctttt
     6301 atgacttccc ttgttacatc aatctttgat tgtgctgtag gtgttagatg cagtgtctca
     6361 tggctacgtt gttacagaca aatgatactt gtttgaaggc ttggtcattt attgatctgc
     6421 atggaaattg tgaatactgt atgtaggact aaggaagcag ccagtggaca catggatagg
     6481 ctaatctgtg acatgtcagg aaccaaccac aacaaaagga aggcatccat tggtgtgctg
     6541 cttgtctgct ctgcagttgc tgcctagcct attttcctat gtgaagagac cagagcacct
     6601 ctgctgtgca ttataccacc acattggaga tgcgctcagg agcttatatg ctgaactcga
     6661 tggctcataa gagcactggc tgagtggtgc cttagttcca gtactcaaga gccaaaggct
     6721 ggtgggtctc tgagttcaag gtcagcctgg tctacagagt gagttccagg atagctaggg
     6781 ctaaacagag aaaccttgtc tctgggagta gggtggggga gcattgtctg cttgtctgga
     6841 taatcccggt ttgatttcca acacctaaat tgtggttcac aaccatctgt tactccagtt
     6901 ccaggggatc tgacaccctg ttctgggcta tttgaacact gcatgcaagt ggtgtacaga
     6961 cgtacatgca ggcaaaacac aataaacata aaattgaaat ataggtttaa gccgggcatg
     7021 gtggcacacg cctttagtcc cagcactcgg gaggcagagg cggcaggcgg atttctgagt
     7081 tcgaggccag cctggtctac aaagtgagtt ccaggacagc cagggctata cagagaaacc
     7141 ctgtctcaaa acaacaacaa caacaaacaa agaagaaaga tttaaaaaaa gtttgtaagc
     7201 tgaaggccta aggagaagtt ccaaagcata attttgcctt ttaaaccttg tagttatgga
     7261 ttttgacaaa tggccaccaa ttagaggagt cacactgcac tgtcatctca gcgctcagga
     7321 gactgaggca ggaagattgc aagcatgggg ctggtctgac ctaacaggga gttttaggct
     7381 ggcctagctt acataaagac cttatctttt aaaaaagaaa tagggggctg gagagatggc
     7441 tcagtggtta agagcactga ctcctcttcc agaggtcctg agttcaattc ccagcaacca
     7501 catggtggct cacaaccatc tgtaatgaga cctgacgccc tcttctggtg tgtctgaaga
     7561 cagtacagtg tactacactg tatactaaat aaataaatct ttaaaaaaaa aaagaaacag
     7621 aaaacaatgt ggtccccagc tgaccatcgg agtgtctgga tgagtagcca gcatactcgt
     7681 gcttacaaag caaaagtgtg gacttgcagc aatatacaac tttgtgatgt gaaaataagt
     7741 gatttggtta gtgttagtat gtttcctaaa taaagttagt atctgttgaa gaggta
//
