LOCUS       NM_146252               3581 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus TBC1 domain family, member 13 (Tbc1d13), mRNA.
ACCESSION   NM_146252
VERSION     NM_146252.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3581)
  AUTHORS   Davey,J.R., Humphrey,S.J., Junutula,J.R., Mishra,A.K.,
            Lambright,D.G., James,D.E. and Stockli,J.
  TITLE     TBC1D13 is a RAB35 specific GAP that plays an important role in
            GLUT4 trafficking in adipocytes
  JOURNAL   Traffic 13 (10), 1429-1441 (2012)
   PUBMED   22762500
  REMARK    GeneRIF: TBC1D13 is a potent inhibitor of insulin-stimulated GLUT4
            translocation in adipocytes.
REFERENCE   2  (bases 1 to 3581)
  AUTHORS   Llorian,M., Beullens,M., Andres,I., Ortiz,J.M. and Bollen,M.
  TITLE     SIPP1, a novel pre-mRNA splicing factor and interactor of protein
            phosphatase-1
  JOURNAL   Biochem J 378 (Pt 1), 229-238 (2004)
   PUBMED   14640981
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL845258.5.
            
            On Jan 7, 2022 this sequence version replaced NM_146252.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK158066.1, SRR7345562.255082.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-154               AL845258.5         20108-20261
            155-228             AL845258.5         21146-21219
            229-269             AL845258.5         23022-23062
            270-331             AL845258.5         23470-23531
            332-431             AL845258.5         23631-23730
            432-514             AL845258.5         26824-26906
            515-674             AL845258.5         28611-28770
            675-885             AL845258.5         33001-33211
            886-1049            AL845258.5         33711-33874
            1050-1210           AL845258.5         34972-35132
            1211-1268           AL845258.5         35280-35337
            1269-3581           AL845258.5         36049-38361
FEATURES             Location/Qualifiers
     source          1..3581
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 21.22 cM"
     gene            1..3581
                     /gene="Tbc1d13"
                     /gene_synonym="2600014A06Rik"
                     /note="TBC1 domain family, member 13"
                     /db_xref="GeneID:70296"
                     /db_xref="MGI:MGI:2385326"
     exon            1..154
                     /gene="Tbc1d13"
                     /gene_synonym="2600014A06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             132..1334
                     /gene="Tbc1d13"
                     /gene_synonym="2600014A06Rik"
                     /codon_start=1
                     /product="TBC1 domain family member 13"
                     /protein_id="NP_666364.1"
                     /db_xref="CCDS:CCDS15871.1"
                     /db_xref="GeneID:70296"
                     /db_xref="MGI:MGI:2385326"
                     /translation="MSSLHKSRIADFQDVLKEPSIVLEKLRELSFSGIPCEGGLRCLC
                     WKILLNYLPLERASWTSILAKQRGLYSQFLREMIIQPGIAKANMGVFREDVTFEDHPL
                     NPNPDSRWNTYFKDNEVLLQIDKDVRRLCPDISFFQRATEYPCLLILDPQNEFETLRK
                     RVEQTTLKSQTVARNRSGVTNMSSPHKNSAPSALNEYEVLPNGCEAHWEVVERILFIY
                     AKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKS
                     LDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQSIKPQFFAFRWLTLLLSQEFLLPDV
                     IRIWDSLFADGNRFDFLLLVCCAMLILIREQLLEGDFTVNMRLLQDYPITDVCQILQK
                     AKELQDSK"
     exon            155..228
                     /gene="Tbc1d13"
                     /gene_synonym="2600014A06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            229..269
                     /gene="Tbc1d13"
                     /gene_synonym="2600014A06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            270..331
                     /gene="Tbc1d13"
                     /gene_synonym="2600014A06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            332..431
                     /gene="Tbc1d13"
                     /gene_synonym="2600014A06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            432..514
                     /gene="Tbc1d13"
                     /gene_synonym="2600014A06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            515..674
                     /gene="Tbc1d13"
                     /gene_synonym="2600014A06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            675..885
                     /gene="Tbc1d13"
                     /gene_synonym="2600014A06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            886..1049
                     /gene="Tbc1d13"
                     /gene_synonym="2600014A06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1050..1210
                     /gene="Tbc1d13"
                     /gene_synonym="2600014A06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1268
                     /gene="Tbc1d13"
                     /gene_synonym="2600014A06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1269..3581
                     /gene="Tbc1d13"
                     /gene_synonym="2600014A06Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3559..3564
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tbc1d13"
                     /gene_synonym="2600014A06Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3581
                     /gene="Tbc1d13"
                     /gene_synonym="2600014A06Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcgcacgctc caagttctgc ttcctgccgg aggcttttgc ccagcgcccc gtgtccccgg
       61 agggaggggg gcggtggcgg tggcggcagc tggggctgca gaagcagctc gggagtccgg
      121 aagtcaacac catgtcgagt ctgcacaaga gccggattgc agatttccag gatgtcctga
      181 aggagccctc cattgtgttg gaaaagcttc gagaactcag ttttagtggc atcccctgtg
      241 agggcggact gcggtgcctc tgctggaaga tcctcctgaa ctacctccct ctggagagag
      301 cctcgtggac ttccatcctg gccaagcaga gggggctcta ttcgcagttc ctgagagaga
      361 tgattatcca gcctggcatt gccaaggcca acatgggtgt attcagggag gatgtgacct
      421 ttgaggacca tcctctgaac ccaaaccctg acagcaggtg gaacacatat tttaaggaca
      481 acgaggtgct actccagatt gacaaagatg tcaggaggtt gtgcccagat atatctttct
      541 tccaaagagc cactgagtac ccctgcctgc tcatcctgga cccgcaaaat gagtttgaga
      601 cccttcgtaa gcgggtggag cagacgacac tgaagtctca gacggtggcc aggaatcgaa
      661 gcggggttac aaatatgagc tccccgcaca agaacagtgc gccatcagcc ctgaacgagt
      721 atgaggtgct acccaatggc tgcgaagccc actgggaggt ggtggagcgc atcctgttca
      781 tctatgccaa gctcaaccct ggcatcgctt acgtgcaggg catgaatgag atcgtgggcc
      841 ccctctacta cacttttgcc actgacccta acagcgagtg gaaagagcac gctgaagcag
      901 ataccttttt ctgcttcacc aacctcatgg ctgagatccg ggacaacttc atcaagagcc
      961 tggatgactc ccagtgcggt atcacctaca agatggaaaa ggtgtactcc accttgaagg
     1021 ataaggatgt agagctctac ctgaagctgc aagagcagag tatcaagcct cagttctttg
     1081 ccttccgatg gctgacattg ctgctgtccc aggagttctt gctgcctgat gtcatccgta
     1141 tctgggactc cctctttgct gatggcaacc gattcgattt cctcctcctg gtctgctgtg
     1201 ctatgctcat actgatccgg gagcagttac tggaggggga cttcactgtc aacatgcggc
     1261 ttctgcagga ttaccccatc acagacgtct gccagatcct acagaaagcc aaggaactcc
     1321 aagactcgaa gtaacgtggt agcagggtcc cagctttgga agagcagcca ctgcgcttgc
     1381 tccacaccct tgttttgggg acacaaagga gcctgtgaga aagccagcct gaagggaagc
     1441 tacagtcctg gccagctcca ggtcttccca gcctggttcc catggtccag ggtgctcctg
     1501 gagcacgccg cgatgcgctc cttcccagtg ctcagccctg ccacactccc tgcacctcag
     1561 ccctgggacc ctccacccag actgctcagc agggccggag ctcctgaact ggcttcctgg
     1621 ggctggggcc atttggggcc taggaggctg acagggtcct gccatgcctc tgcccagtag
     1681 ctcctcaccc ctgtgctttc atcttccctg agtcctggtc aggggaggca attagctaat
     1741 gggccagaaa caacttctga gtgttggtgc tcagactgcc tggggaagca ccccagaaga
     1801 gctgagtgac tgccagttct agggccaccg tttgtccctg tccggtgtgt ttgcttgtgg
     1861 ccggtagggt tgtctcccag gtctctgctt tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg
     1921 tgtgtgtatg tgtgtgtgta tgtatgtata catgtgtgtt cacacatgcc ctggcagtgg
     1981 ggtgagggta tgtgggaacc ctctaaggcc ctgcttcccc tctgtgtcta cctctgcctg
     2041 tcccttttct tcctttgcca gaggcgtgtg tggctcctgc tgtctttctt ttgtctgtcc
     2101 tctttaccct ggcgctctcc tcccctctgc tccctgaggc cagcattcag gagtgtagct
     2161 tagtgagaaa gccctggagg ccaactttat tggcatcctg ttcccatccc cagcctgagg
     2221 cctccaggtc ctctatgtca gagcaggaat ccccagtacc tgctccaatg gcagcctgtg
     2281 atgctttgag cctctcgccc attttctact caagaatgga gaaaggaggg atggggagag
     2341 ccttcagttg gagagtaaga taccctggct gctgtgtgcc tgggagttgc catttcagga
     2401 gtgatgtcat ctctttgatg gccatgttcc catctggtgt gtgtagttct catcaagggc
     2461 aagggaccaa agaaagcttc tctgggtcca gggtggctaa actggaaggc ctggagcttc
     2521 acagtaccag agggctacct ctgccatctg cccccatggg aggcggagcg gggaggcggc
     2581 gggggggggg gggggggggg gaggcttcgg aggtgctggc cttcctggtc atgtgcttga
     2641 tctatcttct gactttgggg ctgggttccc tgaaccctat agacttttct gaccatgttt
     2701 cttccggagg tcaggtggct tgagtcctga aggcaggttg gcagcaaggg ctcttaacct
     2761 tctccagaga ctggccagca ggagtgaggc tccagtagct ggcacctgaa gccttcctga
     2821 gagcagaggg cagggctgcc tccttcccag gccattgctt tagccaggtt gggttgagtg
     2881 ctgctgggac tctacctgcc tttttactac cttctctctc aatacacaac acctgggacg
     2941 tattttacta tttatttgga cacaggctag ctatttattg cagagtggca agtgacctgg
     3001 ggaggagtgg ccaggatgct aaaggagttg gagaattcaa atatggattg tcttattccc
     3061 caaggttaac cctgacatcc tctccccgtt cctgcctgag agggctgcca gctttaccct
     3121 agagccgagt ataagggagg ccatatacac tcccgccatc ttgaccgccc ccagacctag
     3181 gacttggtag ctggtagctc agccccagta ctgctccctt tgttgactgg gacgcagcaa
     3241 atgctgccca ggacgcggat gcattcattc cttcttgcct gcctccccca ccccacccct
     3301 tgccccgttt cctgggacca tgctactgga atcactgcat ctgatttgtt tctgtgggag
     3361 acctgcatcc tgtgcccacc acttggtcct tgagatgaag gccaaggaca tggagacttt
     3421 gtcttgggta gggtggctcc gcagttggac gctgcctgag ggaaggatct gcccttgatt
     3481 cttaaggggg aaccccgagc ctgagctcct gcagctcccg ggagctcagc aggccagggc
     3541 tgttgatgag tcgtccttaa taaactgtgc tctttaccat g
//
