LOCUS       NM_145952               3933 bp    mRNA    linear   ROD 07-AUG-2024
DEFINITION  Mus musculus TBC1D12: TBC1 domain family, member 12 (Tbc1d12),
            transcript variant 1, mRNA.
ACCESSION   NM_145952
VERSION     NM_145952.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3933)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC101775.10.
            
            On Apr 8, 2022 this sequence version replaced NM_145952.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK172979.1, BC138057.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-856               AC101775.10        29999-30854
            857-980             AC101775.10        59024-59147
            981-1096            AC101775.10        76067-76182
            1097-1179           AC101775.10        89395-89477
            1180-1297           AC101775.10        92277-92394
            1298-1404           AC101775.10        94717-94823
            1405-1485           AC101775.10        101180-101260
            1486-1574           AC101775.10        104415-104503
            1575-1646           AC101775.10        106599-106670
            1647-1775           AC101775.10        107337-107465
            1776-1885           AC101775.10        107712-107821
            1886-2144           AC101775.10        110020-110278
            2145-3933           AC101775.10        111279-113067
FEATURES             Location/Qualifiers
     source          1..3933
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 33.47 cM"
     gene            1..3933
                     /gene="Tbc1d12"
                     /note="TBC1D12: TBC1 domain family, member 12"
                     /db_xref="GeneID:209478"
                     /db_xref="MGI:MGI:2384803"
     exon            1..856
                     /gene="Tbc1d12"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..2213
                     /gene="Tbc1d12"
                     /note="isoform 1 is encoded by transcript variant 1; TBC1
                     domain family member 12"
                     /codon_start=1
                     /product="TBC1 domain family member 12 isoform 1"
                     /protein_id="NP_666064.3"
                     /db_xref="CCDS:CCDS37975.1"
                     /db_xref="GeneID:209478"
                     /db_xref="MGI:MGI:2384803"
                     /translation="MMGPEDAGACSGRNAELLPVPGPMGQDGKTVPATSGFSGGAVAA
                     EPPEEAGEEEAPPPRQLLQRYLAAAAGPLKPGLGGAEAEAEEAAAAAVPAARGSGMTN
                     GDSGFLLRQDRRGPEEARRRRTCGRPCLLEPADEGVDGAGGLDDWAAPLEDPLRSCCL
                     AAGDTDDPDPAAATPAGRAVESAEPSLGLPDARFGSRNTFEVSRRQSAGDLLPSAGPS
                     APLPAAEQGPGGTTARARRSGGFADFFARNLFPKRTKELKSVVHSAPGWKLFGKVPPR
                     ENLQKTSKIIQQEYEARTGRTCKAAPQSSRRKSFALEPLSTTALILEDRPPNLPAKSV
                     EEALRHRQEYDEMVAEAKKREIKEAHKRKRIMKERFKQEESIASAMVIWINEILPNWE
                     VMRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSESS
                     SENDTEGLSVADREASLELIKLDISRTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDV
                     GYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFE
                     ENLSKLFLHFKSYNLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGL
                     GILRLYEDILLQMDFIHIAQFLTKLPEDITSEKLFSCIAAIQMQNSTKKWTQVFASVA
                     KDIKEGDKNTSPALKS"
     exon            857..980
                     /gene="Tbc1d12"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1096
                     /gene="Tbc1d12"
                     /inference="alignment:Splign:2.1.0"
     exon            1097..1179
                     /gene="Tbc1d12"
                     /inference="alignment:Splign:2.1.0"
     exon            1180..1297
                     /gene="Tbc1d12"
                     /inference="alignment:Splign:2.1.0"
     exon            1298..1404
                     /gene="Tbc1d12"
                     /inference="alignment:Splign:2.1.0"
     exon            1405..1485
                     /gene="Tbc1d12"
                     /inference="alignment:Splign:2.1.0"
     exon            1486..1574
                     /gene="Tbc1d12"
                     /inference="alignment:Splign:2.1.0"
     exon            1575..1646
                     /gene="Tbc1d12"
                     /inference="alignment:Splign:2.1.0"
     exon            1647..1775
                     /gene="Tbc1d12"
                     /inference="alignment:Splign:2.1.0"
     exon            1776..1885
                     /gene="Tbc1d12"
                     /inference="alignment:Splign:2.1.0"
     exon            1886..2144
                     /gene="Tbc1d12"
                     /inference="alignment:Splign:2.1.0"
     exon            2145..3933
                     /gene="Tbc1d12"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3914..3919
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tbc1d12"
                     /note="hexamer: AATAAA"
     polyA_site      3933
                     /gene="Tbc1d12"
                     /note="major polyA site"
ORIGIN      
        1 gtgcccggcc tccggcaact gccccggccg ccgggtggga ggggtgggtc cggggacgtc
       61 gcggcggccg tggccgcgaa ccctgcacgc agggcagtcc tcctccgccg cctcagatga
      121 tgggtcccga ggatgccgga gcctgctcgg gaaggaacgc cgagctgctc ccagtcccgg
      181 ggcccatggg tcaggacggg aagaccgtcc cggccaccag cggctttagc ggaggcgctg
      241 tcgccgcgga gccgccggag gaggctggag aggaggaggc gccgccgccg cggcagctcc
      301 tgcagcggta cctcgcggcg gccgcgggcc cgctgaagcc cgggctcggc ggggcggagg
      361 cggaggcgga ggaggcggcg gcggcagcag tccccgcggc gcgcggctca ggcatgacca
      421 acggagactc gggctttttg ctgcgccagg accgtcgcgg cccagaggag gcacgtcgcc
      481 gccgaacctg cggccgtccc tgcctgctgg agcccgcgga cgagggcgtg gacggtgcgg
      541 gtggcctgga cgactgggcc gcgccgctcg aggacccgct gcggagctgc tgcctggcgg
      601 ccggggacac ggacgacccg gaccccgcag ccgccacccc tgccgggagg gccgtcgaga
      661 gcgcggagcc cagcctcggc ctccccgacg cccgcttcgg ctctcggaac acgttcgagg
      721 tgagccgccg tcagagcgcc ggcgacctcc tgccctcagc ggggccgtcc gcacccttgc
      781 cagcggcaga gcagggtccc gggggcacca cggctcgggc tcgacggagc ggtggcttcg
      841 cggatttctt cgccagaaac cttttcccaa aaaggacaaa ggaactcaaa tcagttgtcc
      901 atagtgctcc tggctggaag ttatttggta aagtccctcc cagagaaaat cttcagaaaa
      961 cctccaaaat tattcagcag gagtacgaag ctcgcacagg gaggacctgt aaagcagccc
     1021 cccagtcttc acgacgcaag agctttgcgc tggagccact ttctaccact gccctgattc
     1081 tggaggaccg accaccgaat cttcctgcga aatctgtgga agaagcgctg cgtcaccggc
     1141 aggagtatga tgagatggtg gccgaagcta aaaaacgaga aattaaagaa gcacataaaa
     1201 gaaaaagaat aatgaaagaa cgatttaagc aggaagaaag cattgcaagt gcaatggtaa
     1261 tttggatcaa tgaaatactg cccaattggg aagtaatgcg tagtaccaga agagttcgag
     1321 aattgtggtg gcagggattg ccccctagtg tccgtgggaa agtttggagt ctagctgtag
     1381 gaaatgaact aaatatcact cctgaacttt atgaaatctt tctttcaaga gcaaaagaac
     1441 gttggaaaag cttcagtgaa tcaagttctg agaacgacac ggaaggtcta tctgttgctg
     1501 accgagaggc tagtctggaa ttaattaagt tggacatatc ccgtacattt ccatctctct
     1561 acatctttca gaagggtggc ccatatcacg atgttttgca tagtatctta ggggcatata
     1621 catgttacag acctgatgtt ggttatgtcc aggggatgtc cttcatcgca gccgttctca
     1681 tcctcaatct ggaggaagca gacgccttca ttgcgttcgc gaatctccta aacaagccgt
     1741 gccaactggc ctttttccga gtggatcaca gcatgatgtt gaagtatttt gcaacatttg
     1801 aagtattctt tgaggaaaac ctatccaaac tatttcttca tttcaagtcg tataatctga
     1861 caccagatat atatttgata gattggatct tcacattgta cagcaaatca ctgccacttg
     1921 atctggcttg tcgagtctgg gatgtgtttt gtagagatgg ggaggaattt ttatttagga
     1981 ctggattagg gatcctccgg ctatatgaag atatactcct acagatggac tttattcata
     2041 tagcacaatt tcttaccaaa ttgccagaag atataacatc agaaaagctt ttcagctgca
     2101 tcgcagccat tcagatgcag aatagcacca agaaatggac tcaggtcttt gcatctgtag
     2161 caaaggacat taaagaaggg gacaagaaca ccagccctgc tctgaagagc taacctttga
     2221 gttagtgaca aactgaaatg caaaaggtag ttttcgggga aagttttctc tttcctatgt
     2281 agataccgtg aagaaatgtc ggagagaaga atcgggacct ggaaaaactt ctgggtttaa
     2341 attccacggc tgaagtaaat gaaacgcgta atttattgac agtattaata aaaaagtacc
     2401 tgtggagagc catttttcag aggaaaaggc ttagttggct attacatact ccataatttg
     2461 gagtgaatac tttaatgcaa taattttttt taaaaaaaat agcttcacag aaacttcaat
     2521 ttttatgtcg tttctttttt aacaattaac tacaaatgca cttctggagt cagaatagga
     2581 ttgctaaatc ctactttagt ctccaaaaat gatagaacac atgtattatc tccagttctg
     2641 agcttgggaa gatattctag accagtagta agcaactgag tcgtaagttc cgtccgccac
     2701 tggagctctt gcctgccttg ctcgcaggcc agggaggtcc gcatcctcga gaactggaac
     2761 actggtggac atgattgcct gttttgctta tggagtttcc cacagtgttg tgtccccttg
     2821 gtttttgaag agaaatcttt ctctaagtaa tttctatcac aaaagaattt tcgccttatt
     2881 gtttcttgtc tgcaaattgt tatgtagtaa cttaacatta aaaaaactag gtaactggta
     2941 gaaaggaaga tctttttgca ctttagagga ctgaagactt gactttgaga ataagaataa
     3001 gaaagcaatg aattctaaga gttcgagata acacactact tacaagactt gaatttttta
     3061 gttaaaatcc atgttctatc tatagaaaca aattttatta atttcagttt gaaatttaaa
     3121 actttatata gctaagtcta agacttgtga aactctatgc atattttttt ctaattgatg
     3181 ggaataatag taaaagtaat tttacctttt ttcttagtct aatggcatct cagataaact
     3241 attaatcatt ggtaaattga cattaaattt attactctta atttcttaac ctaacctaaa
     3301 tcatttgagt attatggtta atatcagtat aaaatactat ttggttattg attagattta
     3361 tactgttctg atgttgcaat ttggtttgaa acaacataga agcacacatt tctgttagta
     3421 gtggacatac atatatatag tctttagact aacaagccag agattcttcc ttattggata
     3481 ataaactgcc ttaggagtat gggaccagag gaagtgcata tatttttacc ctatgggttg
     3541 atcattctag cctcaggaac cctgtagaat taactcctgt cataggggct agctcagtga
     3601 aactggtagt ataataaaac agtgagggag tttctagagt cttaataggt tctagcatga
     3661 ggactatccc ttaatattgg tgtctctcat aaaaggcaca taacctccgg gagtaatctc
     3721 attgaattta tattacttgg cctagattta atcttatttt catgtattag tttgctaagg
     3781 tggtcctaca ctctgcattt ctttccctta ttttttttat tgtacagttt ctttacctac
     3841 caagtataaa tgtgtatata aaatgtaaat acaagaaatt cactaaaatc cactagtaac
     3901 aattactatg aaaaataaaa cttgtacaca gaa
//
