LOCUS       NM_001001452             882 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus taste receptor, type 2, member 143 (Tas2r143), mRNA.
ACCESSION   NM_001001452
VERSION     NM_001001452.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 882)
  AUTHORS   Kobayashi,D., Watarai,T., Ozawa,M., Kanda,Y., Saika,F., Kiguchi,N.,
            Takeuchi,A., Ikawa,M., Matsuzaki,S. and Katakai,T.
  TITLE     Tas2R signaling enhances mouse neutrophil migration via a
            ROCK-dependent pathway
  JOURNAL   Front Immunol 13, 973880 (2022)
   PUBMED   36059440
  REMARK    GeneRIF: Tas2R signaling enhances mouse neutrophil migration via a
            ROCK-dependent pathway.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 882)
  AUTHORS   Lu,P., ElMallah,M.K., Liu,Z., Wu,C., Chen,J., Lifshitz,L.M. and
            ZhuGe,R.
  TITLE     Genetic deletion of the Tas2r143/Tas2r135/Tas2r126 cluster reveals
            that TAS2Rs may not mediate bitter tastant-induced bronchodilation
  JOURNAL   J Cell Physiol 236 (9), 6407-6423 (2021)
   PUBMED   33559206
  REMARK    GeneRIF: Genetic deletion of the Tas2r143/Tas2r135/Tas2r126 cluster
            reveals that TAS2Rs may not mediate bitter tastant-induced
            bronchodilation.
REFERENCE   3  (bases 1 to 882)
  AUTHORS   Conte,C., Ebeling,M., Marcuz,A., Nef,P. and Andres-Barquin,P.J.
  TITLE     Evolutionary relationships of the Tas2r receptor gene families in
            mouse and human
  JOURNAL   Physiol Genomics 14 (1), 73-82 (2003)
   PUBMED   12734386
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 882)
  AUTHORS   Shi,P., Zhang,J., Yang,H. and Zhang,Y.P.
  TITLE     Adaptive diversification of bitter taste receptor genes in
            Mammalian evolution
  JOURNAL   Mol Biol Evol 20 (5), 805-814 (2003)
   PUBMED   12679530
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY145467.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC148239.1, BC111103.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..882
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 20.7 cM"
     gene            1..882
                     /gene="Tas2r143"
                     /gene_synonym="Gm1404; mt2r36; Tas2r43"
                     /note="taste receptor, type 2, member 143"
                     /db_xref="GeneID:387514"
                     /db_xref="MGI:MGI:2681310"
     CDS             1..882
                     /gene="Tas2r143"
                     /gene_synonym="Gm1404; mt2r36; Tas2r43"
                     /note="T2R43; T2R143; taste receptor type 2 member 43"
                     /codon_start=1
                     /product="taste receptor type 2 member 143"
                     /protein_id="NP_001001452.1"
                     /db_xref="CCDS:CCDS20068.1"
                     /db_xref="GeneID:387514"
                     /db_xref="MGI:MGI:2681310"
                     /translation="MPSTPTLIFIIIFYLVSLASMLQNGFMMIVLGREWMRNRTLPAA
                     DMIVASLASSRFCLHGIAILANLLASFDFCYQANLIGILWDFTNTLIFWLTAWLAIFY
                     CVKISSFSHPVLFWLKWRISQLVPRLLVVSLIIGGLSAVISATGNFMANQMTISQGFH
                     GNCTFGHMSLDFYRYYYLYHSVLMWFTPFFLFLVSVIVLMFSLYQHVEKMRGHRPGPW
                     DLHTQAHTMALKSLTFFFIFYIFFFLALVISSTKRKSMQSYYWAREAIIYTGIFLNSI
                     ILLFSNPKLRKALKMRF"
     exon            1..882
                     /gene="Tas2r143"
                     /gene_synonym="Gm1404; mt2r36; Tas2r43"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgccctcca cacccacatt gatcttcatt atcatctttt acctggtgtc attggcctct
       61 atgttgcaga atggcttcat gatgattgtg ctgggcagag agtggatgag gaaccggaca
      121 ctaccggcag ctgacatgat tgtggcctct cttgcttcct cccggttctg cttgcatggg
      181 atcgccatcc tggccaacct cttggcctcc tttgattttt gttaccaagc gaaccttatt
      241 ggcatcctct gggatttcac taacactctc attttttggc ttactgcctg gcttgccatc
      301 ttctactgtg tgaagatctc ctctttctcc caccctgtcc tcttttggct caagtggagg
      361 atttcccagt tagttcccag gctgctggtt gtatctctca tcataggtgg cctgtcagct
      421 gtcatttcag ccaccgggaa cttcatggcc aatcagatga ccatctccca gggtttccat
      481 ggaaactgca cttttggtca catgtcactg gacttctatc ggtactatta cctgtatcac
      541 tcagtgctca tgtggttcac tcctttcttc ctgtttctag tgtccgttat cgtgctcatg
      601 ttctcactgt accagcatgt ggagaagatg aggggccaca ggcctgggcc ttgggatctc
      661 catactcagg cacataccat ggctctgaaa tcccttacct tcttcttcat cttttatatc
      721 ttttttttct tggccctggt aatttctagt acaaaaagga aaagcatgca gagttactat
      781 tgggccagag aggctatcat ctacacaggc atctttttga actccatcat cctgctgttt
      841 agcaacccca aactgagaaa ggccctgaag atgaggtttt ag
//
