LOCUS       NM_001001451             996 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus taste receptor, type 2, member 138 (Tas2r138), mRNA.
ACCESSION   NM_001001451
VERSION     NM_001001451.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 996)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 996)
  AUTHORS   Pu,Q., Guo,K., Lin,P., Wang,Z., Qin,S., Gao,P., Combs,C., Khan,N.,
            Xia,Z. and Wu,M.
  TITLE     Bitter receptor TAS2R138 facilitates lipid droplet degradation in
            neutrophils during Pseudomonas aeruginosa infection
  JOURNAL   Signal Transduct Target Ther 6 (1), 210 (2021)
   PUBMED   34083514
  REMARK    GeneRIF: Bitter receptor TAS2R138 facilitates lipid droplet
            degradation in neutrophils during Pseudomonas aeruginosa infection.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 996)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 996)
  AUTHORS   Prandi,S., Bromke,M., Hubner,S., Voigt,A., Boehm,U., Meyerhof,W.
            and Behrens,M.
  TITLE     A subset of mouse colonic goblet cells expresses the bitter taste
            receptor Tas2r131
  JOURNAL   PLoS One 8 (12), e82820 (2013)
   PUBMED   24367558
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 996)
  AUTHORS   Wu,S.V., Chen,M.C. and Rozengurt,E.
  TITLE     Genomic organization, expression, and function of bitter taste
            receptors (T2R) in mouse and rat
  JOURNAL   Physiol Genomics 22 (2), 139-149 (2005)
   PUBMED   15886333
REFERENCE   6  (bases 1 to 996)
  AUTHORS   Conte,C., Ebeling,M., Marcuz,A., Nef,P. and Andres-Barquin,P.J.
  TITLE     Evolutionary relationships of the Tas2r receptor gene families in
            mouse and human
  JOURNAL   Physiol Genomics 14 (1), 73-82 (2003)
   PUBMED   12734386
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 996)
  AUTHORS   Shi,P., Zhang,J., Yang,H. and Zhang,Y.P.
  TITLE     Adaptive diversification of bitter taste receptor genes in
            Mammalian evolution
  JOURNAL   Mol Biol Evol 20 (5), 805-814 (2003)
   PUBMED   12679530
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF532789.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC128016.1, AY916509.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..996
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 18.82 cM"
     gene            1..996
                     /gene="Tas2r138"
                     /gene_synonym="mt2r31; T2R138; T2R38; Tas2r38"
                     /note="taste receptor, type 2, member 138"
                     /db_xref="GeneID:387513"
                     /db_xref="MGI:MGI:2681306"
     CDS             1..996
                     /gene="Tas2r138"
                     /gene_synonym="mt2r31; T2R138; T2R38; Tas2r38"
                     /codon_start=1
                     /product="taste receptor type 2 member 38"
                     /protein_id="NP_001001451.1"
                     /db_xref="CCDS:CCDS20038.1"
                     /db_xref="GeneID:387513"
                     /db_xref="MGI:MGI:2681306"
                     /translation="MLSLTPVLTVSYEAKISFLFLSAMEFAVGILANAFIVLVNVWDV
                     VKKQPLNNCDIALLCLSITRLFLQGLLLLDAIQLACFQQMKDPLSHNYQAILTLWMIA
                     NQVSLWLAACLSLLYCSKIVRFSHTFPLHVASWVSRRFLQMLLVVLLLSCICTALCLW
                     DFFCRSHSTVTSLLHLNSTEFSLQIAKLNFFYSFIFCNVGSVPPSLAFLVSSGVLVIS
                     LGSHMRTMKSQTSSSGDPSLEAHIRAIIFLISFFCFYVVSFCAALISIPLLMLWHNKG
                     GVMICIGMMAACPSGHAAILISGNAKLRRAIETMLFWFQSRQKVRPVHKVPPRTL"
     exon            1..996
                     /gene="Tas2r138"
                     /gene_synonym="mt2r31; T2R138; T2R38; Tas2r38"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgctgagtc tgactcctgt cttaactgtg tcctatgaag ccaagatttc atttctgttc
       61 ctttcagcca tggagtttgc agtgggaatc ctggccaacg ccttcattgt cttggtaaat
      121 gtttgggatg tggtaaaaaa gcagcccttg aacaactgtg acatcgcact gctgtgtctc
      181 agcatcactc ggcttttcct gcagggcctt ctgcttctgg atgctattca gctcgcctgc
      241 ttccagcaga tgaaagaccc actgagccac aactaccaag ccatcctcac tctctggatg
      301 attgcaaacc aagtgagcct ctggctggct gcctgcctca gtctcctcta ctgctccaag
      361 attgtccgct tctctcacac ctttccactc catgtagcaa gctgggtctc caggagattt
      421 cttcagatgc ttctagttgt tcttcttctc tcctgcatct gcactgccct ttgtttgtgg
      481 gacttttttt gcagatctca ctccacggtc acatctctac tgcacctgaa cagcacagaa
      541 ttcagtttgc aaattgcaaa actcaatttc ttttactcgt ttatcttctg caatgtgggc
      601 tctgtccccc cttctctagc tttcctggtt tcctcgggag tgctggttat ctccctgggg
      661 agtcacatga ggactatgaa gtcccaaacc agcagctctg gtgaccccag ccttgaggcc
      721 cacatcagag ccatcatatt tctgatctcc tttttctgtt tttacgtggt gtcattctgt
      781 gctgctttaa tatcaatacc cttactgatg ctatggcaca ataagggggg agtgatgatt
      841 tgtataggga tgatggcagc ttgtccttcg ggacatgcag ccatcctgat atcaggcaat
      901 gctaagctga ggagggccat agagaccatg ctattctggt ttcaaagcag gcaaaaggtg
      961 agaccagtcc acaaggttcc tcccaggaca ctctga
//
