LOCUS       NM_199159                966 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus taste receptor, type 2, member 135 (Tas2r135), mRNA.
ACCESSION   NM_199159
VERSION     NM_199159.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 966)
  AUTHORS   Lu,P., ElMallah,M.K., Liu,Z., Wu,C., Chen,J., Lifshitz,L.M. and
            ZhuGe,R.
  TITLE     Genetic deletion of the Tas2r143/Tas2r135/Tas2r126 cluster reveals
            that TAS2Rs may not mediate bitter tastant-induced bronchodilation
  JOURNAL   J Cell Physiol 236 (9), 6407-6423 (2021)
   PUBMED   33559206
  REMARK    GeneRIF: Genetic deletion of the Tas2r143/Tas2r135/Tas2r126 cluster
            reveals that TAS2Rs may not mediate bitter tastant-induced
            bronchodilation.
REFERENCE   2  (bases 1 to 966)
  AUTHORS   Avau,B., Bauters,D., Steensels,S., Vancleef,L., Laermans,J.,
            Lesuisse,J., Buyse,J., Lijnen,H.R., Tack,J. and Depoortere,I.
  TITLE     The Gustatory Signaling Pathway and Bitter Taste Receptors Affect
            the Development of Obesity and Adipocyte Metabolism in Mice
  JOURNAL   PLoS One 10 (12), e0145538 (2015)
   PUBMED   26692363
  REMARK    GeneRIF: The role of Tas2R135 in the development of obesity and
            adipocyte metabolism
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 966)
  AUTHORS   Conte,C., Ebeling,M., Marcuz,A., Nef,P. and Andres-Barquin,P.J.
  TITLE     Evolutionary relationships of the Tas2r receptor gene families in
            mouse and human
  JOURNAL   Physiol Genomics 14 (1), 73-82 (2003)
   PUBMED   12734386
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 966)
  AUTHORS   Shi,P., Zhang,J., Yang,H. and Zhang,Y.P.
  TITLE     Adaptive diversification of bitter taste receptor genes in
            Mammalian evolution
  JOURNAL   Mol Biol Evol 20 (5), 805-814 (2003)
   PUBMED   12679530
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF532786.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC115532.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..966
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 20.71 cM"
     gene            1..966
                     /gene="Tas2r135"
                     /gene_synonym="mt2r38; Tas2r35"
                     /note="taste receptor, type 2, member 135"
                     /db_xref="GeneID:387512"
                     /db_xref="MGI:MGI:2681302"
     CDS             1..966
                     /gene="Tas2r135"
                     /gene_synonym="mt2r38; Tas2r35"
                     /note="T2R35; T2R135; taste receptor type 2 member 35"
                     /codon_start=1
                     /product="taste receptor type 2 member 135"
                     /protein_id="NP_954610.1"
                     /db_xref="CCDS:CCDS20069.1"
                     /db_xref="GeneID:387512"
                     /db_xref="MGI:MGI:2681302"
                     /translation="MGPIMSTGEMSTGHTVLGCQTTDKTVVTLFIILVLLCLVAVVGN
                     GFIIIALGMKWLLRRTLSAHNKLLISLAASRFCLQCVVIGKNIYVFLNPTSFPYNPVI
                     QLLNLMWDFLTAATIWLCSLLGFFYCVKIATLTHPVFVWLKYRLPGWVPWMLLSAVGM
                     SSLTSILCFIGNYMIYQNHAKSGHQPWNVTGNSLRHSLEKFYFFSIKIIMWTIPTVVF
                     SIFMSLLLVSLVRHMKKTFLALSELRDVWAQAHFKALLPLLSFIVLFISCFLTLVLSS
                     ASNTPYQEFRYWMWQVVIHLCTVIHPIVILFSNPVLRVVIKRGCC"
     exon            1..966
                     /gene="Tas2r135"
                     /gene_synonym="mt2r38; Tas2r35"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgggaccca tcatgtccac aggagaaatg agcacaggcc atacagttct tggatgtcag
       61 actactgata agacagtcgt caccttattt atcattttag tccttttgtg cctggtggca
      121 gtggtaggca atggatttat cattatagca ctgggcatga aatggttgct ccggagaaca
      181 ctgtcagctc ataataagtt actgatcagt ctagcagcct ctcgattctg tctccaatgt
      241 gtggtgatag gtaagaatat ttatgttttc ctgaatccaa caagcttccc atacaaccct
      301 gtaatacagc tcctaaattt aatgtgggac ttcttgactg ctgcaaccat ctggctctgt
      361 tctttgctag gtttcttcta ttgtgtgaaa attgcaacct taacccatcc tgtctttgtc
      421 tggctaaagt acaggttgcc tgggtgggta ccatggatgc tgctcagtgc tgtggggatg
      481 tcgagcttaa ctagtatcct atgtttcata ggcaattata tgatatatca gaaccatgca
      541 aagagtggcc atcaaccttg gaatgtcact gggaatagct taagacactc acttgagaaa
      601 ttctacttct tttctataaa gataatcatg tggacaattc ccactgttgt cttcagcatc
      661 ttcatgagtt tgctcctcgt atctttggta agacacatga agaagacttt cttggccctt
      721 tcagaacttc gggatgtctg ggcacaggcc catttcaagg ctcttcttcc tctgctctcc
      781 ttcatcgtcc ttttcatctc ctgttttctg acgctggtac tcagttctgc cagcaacaca
      841 ccatatcagg aattcaggta ctggatgtgg caggtggtga ttcatctgtg cacagtgata
      901 catcccattg ttatactctt cagcaaccct gttttgagag tggtgataaa gaggggctgc
      961 tgctga
//
