LOCUS       NM_199156                939 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus taste receptor, type 2, member 130 (Tas2r130), mRNA.
ACCESSION   NM_199156
VERSION     NM_199156.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 939)
  AUTHORS   Vadasz,C., Saito,M., Gyetvai,B.M., Oros,M., Szakall,I.,
            Kovacs,K.M., Prasad,V.V., Morahan,G. and Toth,R.
  TITLE     Mapping of QTLs for oral alcohol self-administration in B6.C and
            B6.I quasi-congenic RQI strains
  JOURNAL   Neurochem Res 32 (7), 1099-1112 (2007)
   PUBMED   17273929
REFERENCE   2  (bases 1 to 939)
  AUTHORS   Nelson,T.M., Munger,S.D. and Boughter,J.D. Jr.
  TITLE     Haplotypes at the Tas2r locus on distal chromosome 6 vary with
            quinine taste sensitivity in inbred mice
  JOURNAL   BMC Genet 6, 32 (2005)
   PUBMED   15938754
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 939)
  AUTHORS   Scalzo,A.A., Wheat,R., Dubbelde,C., Stone,L., Clark,P., Du,Y.,
            Dong,N., Stoll,J., Yokoyama,W.M. and Brown,M.G.
  TITLE     Molecular genetic characterization of the distal NKC recombination
            hotspot and putative murine CMV resistance control locus
  JOURNAL   Immunogenetics 55 (6), 370-378 (2003)
   PUBMED   12920489
REFERENCE   4  (bases 1 to 939)
  AUTHORS   Conte,C., Ebeling,M., Marcuz,A., Nef,P. and Andres-Barquin,P.J.
  TITLE     Evolutionary relationships of the Tas2r receptor gene families in
            mouse and human
  JOURNAL   Physiol Genomics 14 (1), 73-82 (2003)
   PUBMED   12734386
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 939)
  AUTHORS   Shi,P., Zhang,J., Yang,H. and Zhang,Y.P.
  TITLE     Adaptive diversification of bitter taste receptor genes in
            Mammalian evolution
  JOURNAL   Mol Biol Evol 20 (5), 805-814 (2003)
   PUBMED   12679530
REFERENCE   6  (bases 1 to 939)
  AUTHORS   Zhang,Y., Hoon,M.A., Chandrashekar,J., Mueller,K.L., Cook,B.,
            Wu,D., Zuker,C.S. and Ryba,N.J.
  TITLE     Coding of sweet, bitter, and umami tastes: different receptor cells
            sharing similar signaling pathways
  JOURNAL   Cell 112 (3), 293-301 (2003)
   PUBMED   12581520
REFERENCE   7  (bases 1 to 939)
  AUTHORS   Montmayeur,J.P. and Matsunami,H.
  TITLE     Receptors for bitter and sweet taste
  JOURNAL   Curr Opin Neurobiol 12 (4), 366-371 (2002)
   PUBMED   12139982
  REMARK    Review article
REFERENCE   8  (bases 1 to 939)
  AUTHORS   Wu,S.V., Rozengurt,N., Yang,M., Young,S.H., Sinnett-Smith,J. and
            Rozengurt,E.
  TITLE     Expression of bitter taste receptors of the T2R family in the
            gastrointestinal tract and enteroendocrine STC-1 cells
  JOURNAL   Proc Natl Acad Sci U S A 99 (4), 2392-2397 (2002)
   PUBMED   11854532
REFERENCE   9  (bases 1 to 939)
  AUTHORS   Margolskee,R.F.
  TITLE     Molecular mechanisms of bitter and sweet taste transduction
  JOURNAL   J Biol Chem 277 (1), 1-4 (2002)
   PUBMED   11696554
  REMARK    Review article
REFERENCE   10 (bases 1 to 939)
  AUTHORS   Adler,E., Hoon,M.A., Mueller,K.L., Chandrashekar,J., Ryba,N.J. and
            Zuker,C.S.
  TITLE     A novel family of mammalian taste receptors
  JOURNAL   Cell 100 (6), 693-702 (2000)
   PUBMED   10761934
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF462604.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..939
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 63.44 cM"
     gene            1..939
                     /gene="Tas2r130"
                     /gene_synonym="mt2r42; STC74; T2R30; Tas2r30; Tas2r7"
                     /note="taste receptor, type 2, member 130"
                     /db_xref="GeneID:387355"
                     /db_xref="MGI:MGI:2681278"
     CDS             1..939
                     /gene="Tas2r130"
                     /gene_synonym="mt2r42; STC74; T2R30; Tas2r30; Tas2r7"
                     /note="T2R6; T2R7; STC7-4; STC 7-4"
                     /codon_start=1
                     /product="taste receptor type 2 member 7"
                     /protein_id="NP_954607.1"
                     /db_xref="CCDS:CCDS20608.1"
                     /db_xref="GeneID:387355"
                     /db_xref="MGI:MGI:2681278"
                     /translation="MTYETDTTLMLVAVGEALVGILGNAFIALVNFMGWMKNRKIASI
                     DLILSSVAMSRICLQCIILLDCIILVQYPDTYNRGKEMRTVDFFWTLTNHLSVWFATC
                     LSIFYLFKIANFFHPLFLWIKWRIDKLILRTLLACVIISLCFSLPVTENLSDDFRRCV
                     KTKERINSTLRCKVNKAGHASVKVNLNLVMLFPFSVSLVSFLLLILSLWRHTRQIQLS
                     VTGYKDPSTTAHVKAMKAVISFLALFVVYCLAFLIATSSYFMPESELAVIWGELIALI
                     YPSSHSFILILGSSKLKQASVRVLCRVKTMLKGKKY"
     exon            1..939
                     /gene="Tas2r130"
                     /gene_synonym="mt2r42; STC74; T2R30; Tas2r30; Tas2r7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgacatacg aaacagatac taccttaatg cttgtagctg ttggtgaggc cttagtaggg
       61 attttaggaa atgcattcat tgcactggta aacttcatgg gctggatgaa gaataggaag
      121 attgcctcta ttgatttaat cctctcaagt gtggccatgt ccagaatttg tctacagtgt
      181 ataatcctat tagattgtat tatattggtg cagtatccag acacctacaa cagaggtaaa
      241 gaaatgagga ccgttgactt cttctggaca cttaccaacc atttaagtgt ctggtttgcc
      301 acctgcctca gcattttcta tttattcaag atagcaaact tcttccaccc tcttttcctc
      361 tggataaagt ggagaattga caagctaatt ctcagaactc tactggcatg tgtgattatc
      421 tccctgtgtt ttagcctccc agtcactgaa aatctgagtg atgatttcag acgttgtgtt
      481 aagacaaagg agagaataaa ctctactttg agatgcaaag taaataaagc tggacatgcc
      541 tctgtcaagg taaatctcaa cttggtcatg ctgttcccct tttctgtgtc tctggtctcc
      601 tttctcctct tgatcctctc cctgtggaga cacaccaggc agatacaact cagtgtaaca
      661 gggtacaaag atcccagcac aacagctcat gtgaaagcca tgaaagcagt aatttccttc
      721 ctggccctgt ttgttgtcta ctgcctagcc tttctcatag ccacctccag ctactttatg
      781 ccagagagtg aattagctgt aatatggggt gagctgatag ctctaatcta tccttcaagc
      841 cattcattta tcctcatcct ggggagtagt aaactaaaac aagcatctgt gagggtgctt
      901 tgtagagtaa agaccatgtt aaagggaaaa aaatattag
//
