LOCUS       NM_207028                927 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus taste receptor, type 2, member 126 (Tas2r126), mRNA.
ACCESSION   NM_207028
VERSION     NM_207028.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 927)
  AUTHORS   Ohmoto,M., Jyotaki,M., Yee,K.K. and Matsumoto,I.
  TITLE     A Transcription Factor Etv1/Er81 Is Involved in the Differentiation
            of Sweet, Umami, and Sodium Taste Cells
  JOURNAL   eNeuro 10 (4) (2023)
   PUBMED   37045597
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 927)
  AUTHORS   Kobayashi,D., Watarai,T., Ozawa,M., Kanda,Y., Saika,F., Kiguchi,N.,
            Takeuchi,A., Ikawa,M., Matsuzaki,S. and Katakai,T.
  TITLE     Tas2R signaling enhances mouse neutrophil migration via a
            ROCK-dependent pathway
  JOURNAL   Front Immunol 13, 973880 (2022)
   PUBMED   36059440
  REMARK    GeneRIF: Tas2R signaling enhances mouse neutrophil migration via a
            ROCK-dependent pathway.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 927)
  AUTHORS   Lu,P., ElMallah,M.K., Liu,Z., Wu,C., Chen,J., Lifshitz,L.M. and
            ZhuGe,R.
  TITLE     Genetic deletion of the Tas2r143/Tas2r135/Tas2r126 cluster reveals
            that TAS2Rs may not mediate bitter tastant-induced bronchodilation
  JOURNAL   J Cell Physiol 236 (9), 6407-6423 (2021)
   PUBMED   33559206
  REMARK    GeneRIF: Genetic deletion of the Tas2r143/Tas2r135/Tas2r126 cluster
            reveals that TAS2Rs may not mediate bitter tastant-induced
            bronchodilation.
REFERENCE   4  (bases 1 to 927)
  AUTHORS   Conte,C., Ebeling,M., Marcuz,A., Nef,P. and Andres-Barquin,P.J.
  TITLE     Evolutionary relationships of the Tas2r receptor gene families in
            mouse and human
  JOURNAL   Physiol Genomics 14 (1), 73-82 (2003)
   PUBMED   12734386
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 927)
  AUTHORS   Shi,P., Zhang,J., Yang,H. and Zhang,Y.P.
  TITLE     Adaptive diversification of bitter taste receptor genes in
            Mammalian evolution
  JOURNAL   Mol Biol Evol 20 (5), 805-814 (2003)
   PUBMED   12679530
REFERENCE   6  (bases 1 to 927)
  AUTHORS   Zhang,Y., Hoon,M.A., Chandrashekar,J., Mueller,K.L., Cook,B.,
            Wu,D., Zuker,C.S. and Ryba,N.J.
  TITLE     Coding of sweet, bitter, and umami tastes: different receptor cells
            sharing similar signaling pathways
  JOURNAL   Cell 112 (3), 293-301 (2003)
   PUBMED   12581520
REFERENCE   7  (bases 1 to 927)
  AUTHORS   Montmayeur,J.P. and Matsunami,H.
  TITLE     Receptors for bitter and sweet taste
  JOURNAL   Curr Opin Neurobiol 12 (4), 366-371 (2002)
   PUBMED   12139982
  REMARK    Review article
REFERENCE   8  (bases 1 to 927)
  AUTHORS   Wu,S.V., Rozengurt,N., Yang,M., Young,S.H., Sinnett-Smith,J. and
            Rozengurt,E.
  TITLE     Expression of bitter taste receptors of the T2R family in the
            gastrointestinal tract and enteroendocrine STC-1 cells
  JOURNAL   Proc Natl Acad Sci U S A 99 (4), 2392-2397 (2002)
   PUBMED   11854532
REFERENCE   9  (bases 1 to 927)
  AUTHORS   Margolskee,R.F.
  TITLE     Molecular mechanisms of bitter and sweet taste transduction
  JOURNAL   J Biol Chem 277 (1), 1-4 (2002)
   PUBMED   11696554
  REMARK    Review article
REFERENCE   10 (bases 1 to 927)
  AUTHORS   Adler,E., Hoon,M.A., Mueller,K.L., Chandrashekar,J., Ryba,N.J. and
            Zuker,C.S.
  TITLE     A novel family of mammalian taste receptors
  JOURNAL   Cell 100 (6), 693-702 (2000)
   PUBMED   10761934
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BK001098.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC126974.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..927
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 20.72 cM"
     gene            1..927
                     /gene="Tas2r126"
                     /gene_synonym="mGR26; mt2r35; T2R12; T2R26; Tas2r26;
                     Tas2r41"
                     /note="taste receptor, type 2, member 126"
                     /db_xref="GeneID:387353"
                     /db_xref="MGI:MGI:2681273"
     CDS             1..927
                     /gene="Tas2r126"
                     /gene_synonym="mGR26; mt2r35; T2R12; T2R26; Tas2r26;
                     Tas2r41"
                     /note="T2R41"
                     /codon_start=1
                     /product="taste receptor type 2 member 41"
                     /protein_id="NP_996911.1"
                     /db_xref="CCDS:CCDS20070.1"
                     /db_xref="GeneID:387353"
                     /db_xref="MGI:MGI:2681273"
                     /translation="MLPTLSVFFMLTFVLLCFLGILANGFIVLMLSREWLLRGRLLPS
                     DMILFSLGTSRFFQQCVGLVNSFYYFLHLVEYSGSLARQLISLHWDFLNSATFWFCTW
                     LSVLFCIKIANFSHPAFLWLKWRFPALVPWFLLGSILVSVIVTLLFFWGNHTIYQAFL
                     RRKFTGNTTFKEWNRRLEIDYFMPLKVVTMSIPCSLFLVSILLLISSLRRHSLRMQHN
                     THSLQDPNVQAHSRALKSLISFLVLYAVSFVSMIIDATVFISSDNVWYWPWQIILYFC
                     MSVHPFILITNNLRFRGTFRQLLLLARGFWVA"
     exon            1..927
                     /gene="Tas2r126"
                     /gene_synonym="mGR26; mt2r35; T2R12; T2R26; Tas2r26;
                     Tas2r41"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgctaccaa cattatcagt tttcttcatg ttgacctttg ttctgctctg tttcctgggg
       61 atcctggcca acggcttcat tgtgctgatg ctgagcaggg aatggctact gcgtggtagg
      121 ctgctcccct cggacatgat cctcttcagt ttgggcacct cccgattctt ccagcagtgt
      181 gtgggattgg tcaacagttt ctattacttc ctccatctgg ttgagtactc cgggagcctt
      241 gcccggcagc tcattagtct tcactgggac ttcttgaact cagccacttt ctggttttgt
      301 acctggctca gcgtcctgtt ctgtatcaag attgctaact tctcccatcc tgccttcctg
      361 tggttgaagt ggagattccc agcgttggtg ccctggttct tgttgggctc tatcttggtg
      421 tccgtcattg taactctgct gttcttttgg ggaaaccaca ctatatatca ggcattctta
      481 aggagaaagt ttactgggaa cacaaccttt aaggagtgga acagaaggct ggaaatagac
      541 tatttcatgc ctctgaaagt tgtcaccatg tcaattcctt gttctctttt tctggtctca
      601 attttgctgt tgatcagttc tctcagaagg cattcgctaa gaatgcagca caatacccac
      661 agcttgcaag accccaacgt ccaggctcac agcagagccc tgaagtcact catctcattc
      721 ctggttcttt atgcggtgtc ctttgtgtcc atgatcattg atgctacagt cttcatctcc
      781 tcagataatg tgtggtattg gccctggcaa attatacttt acttttgcat gtctgtacat
      841 ccatttatcc tcatcaccaa taatctcagg ttccgcggca ccttcaggca gctactcctg
      901 ttggccaggg gattctgggt ggcctag
//
