LOCUS       NM_207025               1002 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus taste receptor, type 2, member 123 (Tas2r123), mRNA.
ACCESSION   NM_207025
VERSION     NM_207025.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Nelson,T.M., Munger,S.D. and Boughter,J.D. Jr.
  TITLE     Haplotypes at the Tas2r locus on distal chromosome 6 vary with
            quinine taste sensitivity in inbred mice
  JOURNAL   BMC Genet 6, 32 (2005)
   PUBMED   15938754
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1002)
  AUTHORS   Conte,C., Ebeling,M., Marcuz,A., Nef,P. and Andres-Barquin,P.J.
  TITLE     Evolutionary relationships of the Tas2r receptor gene families in
            mouse and human
  JOURNAL   Physiol Genomics 14 (1), 73-82 (2003)
   PUBMED   12734386
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1002)
  AUTHORS   Shi,P., Zhang,J., Yang,H. and Zhang,Y.P.
  TITLE     Adaptive diversification of bitter taste receptor genes in
            Mammalian evolution
  JOURNAL   Mol Biol Evol 20 (5), 805-814 (2003)
   PUBMED   12679530
REFERENCE   4  (bases 1 to 1002)
  AUTHORS   Zhang,Y., Hoon,M.A., Chandrashekar,J., Mueller,K.L., Cook,B.,
            Wu,D., Zuker,C.S. and Ryba,N.J.
  TITLE     Coding of sweet, bitter, and umami tastes: different receptor cells
            sharing similar signaling pathways
  JOURNAL   Cell 112 (3), 293-301 (2003)
   PUBMED   12581520
REFERENCE   5  (bases 1 to 1002)
  AUTHORS   Montmayeur,J.P. and Matsunami,H.
  TITLE     Receptors for bitter and sweet taste
  JOURNAL   Curr Opin Neurobiol 12 (4), 366-371 (2002)
   PUBMED   12139982
  REMARK    Review article
REFERENCE   6  (bases 1 to 1002)
  AUTHORS   Wu,S.V., Rozengurt,N., Yang,M., Young,S.H., Sinnett-Smith,J. and
            Rozengurt,E.
  TITLE     Expression of bitter taste receptors of the T2R family in the
            gastrointestinal tract and enteroendocrine STC-1 cells
  JOURNAL   Proc Natl Acad Sci U S A 99 (4), 2392-2397 (2002)
   PUBMED   11854532
REFERENCE   7  (bases 1 to 1002)
  AUTHORS   Margolskee,R.F.
  TITLE     Molecular mechanisms of bitter and sweet taste transduction
  JOURNAL   J Biol Chem 277 (1), 1-4 (2002)
   PUBMED   11696554
  REMARK    Review article
REFERENCE   8  (bases 1 to 1002)
  AUTHORS   Adler,E., Hoon,M.A., Mueller,K.L., Chandrashekar,J., Ryba,N.J. and
            Zuker,C.S.
  TITLE     A novel family of mammalian taste receptors
  JOURNAL   Cell 100 (6), 693-702 (2000)
   PUBMED   10761934
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BK001083.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 64.03 cM"
     gene            1..1002
                     /gene="Tas2r123"
                     /gene_synonym="mGR23; mt2r55; T2R23; t2r55; Tas2r23"
                     /note="taste receptor, type 2, member 123"
                     /db_xref="GeneID:353167"
                     /db_xref="MGI:MGI:2681264"
     CDS             1..1002
                     /gene="Tas2r123"
                     /gene_synonym="mGR23; mt2r55; T2R23; t2r55; Tas2r23"
                     /note="STC9-2; T2R123; taste receptor type 2 member 23"
                     /codon_start=1
                     /product="taste receptor type 2 member 123"
                     /protein_id="NP_996908.1"
                     /db_xref="CCDS:CCDS20624.1"
                     /db_xref="GeneID:353167"
                     /db_xref="MGI:MGI:2681264"
                     /translation="MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRR
                     RISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSI
                     WLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFS
                     IAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVA
                     FLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNL
                     GLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL"
     exon            1..1002
                     /gene="Tas2r123"
                     /gene_synonym="mGR23; mt2r55; T2R23; t2r55; Tas2r23"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgttttcac agaaaataaa ctacagccat ttgtttactt tttcaatcac cttgtatgtg
       61 gaaatagtaa cgggaatctt aggacatgga ttcatagcat tagtgaacat catggactgg
      121 gtcaaaagaa gaaggatctc ttcagtggat cagattctca ctgctttggc ccttaccaga
      181 ttcatttatg tcttgtctat gctgatttgc atattgttat tcatgctgtg cccacatttg
      241 cctaggagat cagaaatgct ttcagcaatg ggtattttct gggtagtcaa cagccatttt
      301 agcatctggc ttactacatg cctcggtgtc ttttattttc tcaagatagc caatttttct
      361 aactcttttt ttctttatct aaagtggaga gttaaaaaag tgattttaat aataatcctg
      421 gcatcactga ttttcttgac tttacacatt ttatctttag ggatatatga tcagttctca
      481 attgctgctt atgtaggaaa tatgtcttat agtttgacag atttaacaca attttccagt
      541 actttcttat tctccaactc atccaatgtt ttcttaatca ccaactcatc ccatgttttc
      601 ttacccatca actccctgtt catgctcata cccttcacag tgtccctggt agcctttctc
      661 atgctcatct tctcactgtg gaagcatcac aaaaagatgc aggtcaatgc caaacaacct
      721 agagatgtca gtactatggc ccacattaaa gccttgcaaa ctgtgttctc cttcctgctg
      781 ctgtatgcca tatacttact tttccttatc ataggaattt tgaaccttgg attgatggag
      841 aaaatagtga tactgatatt tgaccacatt tctggagcag tttttcctat aagccactca
      901 tttgtactga ttctgggaaa cagtaagctg agacaagcca gtctttctgt gttgccttgt
      961 ctaaggtgcc agtccaaaga tatggacacc atgggtctct ag
//
