LOCUS       NM_053211                939 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus taste receptor, type 2, member 103 (Tas2r103), mRNA.
ACCESSION   NM_053211 XM_993708
VERSION     NM_053211.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 939)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 939)
  AUTHORS   Church,D.M., Goodstadt,L., Hillier,L.W., Zody,M.C., Goldstein,S.,
            She,X., Bult,C.J., Agarwala,R., Cherry,J.L., DiCuccio,M.,
            Hlavina,W., Kapustin,Y., Meric,P., Maglott,D., Birtle,Z.,
            Marques,A.C., Graves,T., Zhou,S., Teague,B., Potamousis,K.,
            Churas,C., Place,M., Herschleb,J., Runnheim,R., Forrest,D.,
            Amos-Landgraf,J., Schwartz,D.C., Cheng,Z., Lindblad-Toh,K.,
            Eichler,E.E. and Ponting,C.P.
  CONSRTM   Mouse Genome Sequencing Consortium
  TITLE     Lineage-specific biology revealed by a finished genome assembly of
            the mouse
  JOURNAL   PLoS Biol 7 (5), e1000112 (2009)
   PUBMED   19468303
REFERENCE   3  (bases 1 to 939)
  AUTHORS   Nelson,T.M., Munger,S.D. and Boughter,J.D. Jr.
  TITLE     Haplotypes at the Tas2r locus on distal chromosome 6 vary with
            quinine taste sensitivity in inbred mice
  JOURNAL   BMC Genet 6, 32 (2005)
   PUBMED   15938754
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 939)
  AUTHORS   Conte,C., Ebeling,M., Marcuz,A., Nef,P. and Andres-Barquin,P.J.
  TITLE     Evolutionary relationships of the Tas2r receptor gene families in
            mouse and human
  JOURNAL   Physiol Genomics 14 (1), 73-82 (2003)
   PUBMED   12734386
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 939)
  AUTHORS   Shi,P., Zhang,J., Yang,H. and Zhang,Y.P.
  TITLE     Adaptive diversification of bitter taste receptor genes in
            Mammalian evolution
  JOURNAL   Mol Biol Evol 20 (5), 805-814 (2003)
   PUBMED   12679530
REFERENCE   6  (bases 1 to 939)
  AUTHORS   Zhang,Y., Hoon,M.A., Chandrashekar,J., Mueller,K.L., Cook,B.,
            Wu,D., Zuker,C.S. and Ryba,N.J.
  TITLE     Coding of sweet, bitter, and umami tastes: different receptor cells
            sharing similar signaling pathways
  JOURNAL   Cell 112 (3), 293-301 (2003)
   PUBMED   12581520
REFERENCE   7  (bases 1 to 939)
  AUTHORS   Montmayeur,J.P. and Matsunami,H.
  TITLE     Receptors for bitter and sweet taste
  JOURNAL   Curr Opin Neurobiol 12 (4), 366-371 (2002)
   PUBMED   12139982
  REMARK    Review article
REFERENCE   8  (bases 1 to 939)
  AUTHORS   Margolskee,R.F.
  TITLE     Molecular mechanisms of bitter and sweet taste transduction
  JOURNAL   J Biol Chem 277 (1), 1-4 (2002)
   PUBMED   11696554
  REMARK    Review article
REFERENCE   9  (bases 1 to 939)
  AUTHORS   Matsunami,H., Montmayeur,J.P. and Buck,L.B.
  TITLE     A family of candidate taste receptors in human and mouse
  JOURNAL   Nature 404 (6778), 601-604 (2000)
   PUBMED   10766242
REFERENCE   10 (bases 1 to 939)
  AUTHORS   Adler,E., Hoon,M.A., Mueller,K.L., Chandrashekar,J., Ryba,N.J. and
            Zuker,C.S.
  TITLE     A novel family of mammalian taste receptors
  JOURNAL   Cell 100 (6), 693-702 (2000)
   PUBMED   10761934
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BK001091.1.
            
            On Jan 7, 2010 this sequence version replaced XM_993708.2.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..939
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 64.03 cM"
     gene            1..939
                     /gene="Tas2r103"
                     /gene_synonym="EG667992; mGR03; mt2r63; T2R3; Tas2r10;
                     Tas2r3; TRB2"
                     /note="taste receptor, type 2, member 103"
                     /db_xref="GeneID:667992"
                     /db_xref="MGI:MGI:1890257"
     CDS             1..939
                     /gene="Tas2r103"
                     /gene_synonym="EG667992; mGR03; mt2r63; T2R3; Tas2r10;
                     Tas2r3; TRB2"
                     /note="T2R10; T2R103; taste receptor type 2 member 10;
                     taste receptor family B member 2"
                     /codon_start=1
                     /product="taste receptor type 2 member 103"
                     /protein_id="NP_444441.1"
                     /db_xref="CCDS:CCDS51933.1"
                     /db_xref="GeneID:667992"
                     /db_xref="MGI:MGI:1890257"
                     /translation="MVLTIRAILWVTLITIISLEFIIGILGNVFIALVNIIDWVKRGK
                     ISAVDKTYMALAISRTAFLLSLITGFLVSLLDPALLGMRTMVRLLTISWMVTNHFSVW
                     FATCLSIFYFLKIANFSNSIFLVLKWEAKKVVSVTLVVSVIILIMNIIVINKFTDRLQ
                     VNTLQNCSTSNTLKDYGLFLFISTGFTLTPFAVSLTMFLLLIFSLWRHLKNMCHSATG
                     SRDVSTVAHIKGLQTVVTFLLLYTAFVMSLLSESLNINIQHTNLLSHFLRSIGVAFPT
                     GHSCVLILGNSKLRQASLSVILWLRYKYKHIENWGP"
     exon            1..939
                     /gene="Tas2r103"
                     /gene_synonym="EG667992; mGR03; mt2r63; T2R3; Tas2r10;
                     Tas2r3; TRB2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggtgttga caataagggc tattttatgg gtaacattga taactattat aagtctggag
       61 tttatcatag gaattttagg aaatgtattc atagctctcg tgaacatcat agactgggtt
      121 aaaagaggaa agatctctgc agtggataag acctatatgg ccctggccat ctccaggact
      181 gcttttttat tgtcactaat cacagggttc ttggtatcat tattggaccc agctttattg
      241 ggaatgagaa cgatggtaag gctccttact atttcctgga tggtgaccaa tcatttcagt
      301 gtctggtttg caacatgcct cagtatcttt tattttctca agatagctaa tttctcaaat
      361 tctattttcc ttgttctcaa atgggaagct aaaaaagtgg tatcagtgac attggtggta
      421 tctgtgataa tcttgatcat gaacattata gtcataaaca aattcactga cagacttcaa
      481 gtaaacacac tccagaactg tagtacaagt aacactttaa aagattatgg gctcttttta
      541 ttcattagca ctgggtttac actcacccca ttcgctgtgt ctttgacaat gtttcttctg
      601 ctcatcttct ccctgtggag acatctgaag aatatgtgtc acagtgccac aggctccaga
      661 gatgtcagca cagtggccca cataaaaggc ttgcaaactg tggtaacctt cctgttacta
      721 tatactgctt ttgttatgtc acttctttca gagtctttga atattaacat tcaacataca
      781 aatcttcttt ctcatttttt acggagtata ggagtagctt ttcccacagg ccactcctgt
      841 gtactgattc ttggaaacag taagctgagg caagcctctc tttctgtgat attgtggctg
      901 aggtataagt acaaacatat agagaattgg ggcccctaa
//
