LOCUS       NM_001290659            7763 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus tetratricopeptide repeat, ankyrin repeat and
            coiled-coil containing 1 (Tanc1), transcript variant 2, mRNA.
ACCESSION   NM_001290659 XM_006500038
VERSION     NM_001290659.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7763)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 7763)
  AUTHORS   Yang,Q., Liu,H., Zhong,D., Li,Z., Li,J., Xiao,K. and Liu,W.
  TITLE     Tanc1/2 TPR domain interacts with Myo18a C-terminus and undergoes
            liquid-liquid phase separation
  JOURNAL   Biochim Biophys Acta Mol Cell Res 1871 (2), 119650 (2024)
   PUBMED   38092135
  REMARK    GeneRIF: Tanc1/2 TPR domain interacts with Myo18a C-terminus and
            undergoes liquid-liquid phase separation.
REFERENCE   3  (bases 1 to 7763)
  AUTHORS   Avirneni-Vadlamudi,U., Galindo,K.A., Endicott,T.R., Paulson,V.,
            Cameron,S. and Galindo,R.L.
  TITLE     Drosophila and mammalian models uncover a role for the myoblast
            fusion gene TANC1 in rhabdomyosarcoma
  JOURNAL   J Clin Invest 122 (1), 403-407 (2012)
   PUBMED   22182840
REFERENCE   4  (bases 1 to 7763)
  AUTHORS   Han,S., Nam,J., Li,Y., Kim,S., Cho,S.H., Cho,Y.S., Choi,S.Y.,
            Choi,J., Han,K., Kim,Y., Na,M., Kim,H., Bae,Y.C., Choi,S.Y. and
            Kim,E.
  TITLE     Regulation of dendritic spines, spatial memory, and embryonic
            development by the TANC family of PSD-95-interacting proteins
  JOURNAL   J Neurosci 30 (45), 15102-15112 (2010)
   PUBMED   21068316
  REMARK    GeneRIF: These results suggest that TANC1 is important for
            dendritic spine maintenance and spatial memory
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY753173.1, BC079914.1, CX769146.1, AK031162.1 and AK079966.1.
            
            On Mar 15, 2014 this sequence version replaced XM_006500038.1.
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice site in the 5' coding region, compared to variant 1,
            resulting in an isoform (b) that is shorter than isoform a. The 5'
            UTR of this variant is incomplete due to a lack of full-length
            transcript support and splice pattern ambiguity in the upstream
            region.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC141367.1, SRR10223971.1953.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                BY753173.1         156-197
            43-1162             BC079914.1         1-1120
            1163-3405           BC079914.1         1142-3384
            3406-3589           CX769146.1         482-665
            3590-6263           BC079914.1         3569-6242
            6264-7699           AK031162.1         1476-2911
            7700-7763           AK079966.1         900-963
FEATURES             Location/Qualifiers
     source          1..7763
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 33.93 cM"
     gene            1..7763
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /note="tetratricopeptide repeat, ankyrin repeat and
                     coiled-coil containing 1"
                     /db_xref="GeneID:66860"
                     /db_xref="MGI:MGI:1914110"
     exon            1..104
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            105..184
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     CDS             124..5673
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /note="isoform b is encoded by transcript variant 2;
                     protein TANC1; TPR domain, ankyrin-repeat and
                     coiled-coil-containing protein; tetratricopeptide repeat,
                     ankyrin repeat and coiled-coil domain-containing protein
                     1"
                     /codon_start=1
                     /product="protein TANC1 isoform b"
                     /protein_id="NP_001277588.1"
                     /db_xref="CCDS:CCDS71057.1"
                     /db_xref="GeneID:66860"
                     /db_xref="MGI:MGI:1914110"
                     /translation="MLKAVLKKSREGGKGSKKEAGGDFGSETPALSSSGDSPVNSLST
                     TEDTYRVSLAKGVSMSLPSSPLLPRQSLLTQSRSNKKSPGPVRKPKYVESPRVPGDPV
                     MIPFGEGSKPSEPSATEAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNE
                     AMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAASKSPCETISSPSSTLES
                     KDSGIIATITSSSENDDRSGSSLEWNRDGSLRLGVQKGVLHDRRADNCSPVAEEETTG
                     SAESVLPKAEPSAGDGPVPYPQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLR
                     TSIRLPWHNTAGARFAPYKPQEILLKPLLFEVPSITTDSVFVGRDWLFHQIEENLRNT
                     ELAENRGAVVVGSVGFGKTAIISKLVALSCHGSRMRQIASSSPSLSPKSSDPTQDLPG
                     TPLLSPSSSTSALSVTRTPAGPGTADSQRPREDAVKYLASKVVAYHYCQADNTYTCLV
                     PEFVHSIAALLCRSHQLAAYRDLLIKEPQLQSMLSLRSCVQDPVAAFKRGVLEPLTSL
                     RNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIIPKFPTWLKLIVTVRANFQ
                     EIISALPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNISLNGKADAALISKV
                     SSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSA
                     FDRALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQRMEALSCFLIKRRDK
                     TRMFCHPSFREWLVWRADGESTAFLCEPRNGHALLAFMFSRQESKLNRQQTMELGHHI
                     LKAHIFKGLSKKTGVSSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGA
                     NVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMNALCYAAAAGHMK
                     LVCLLIKKGARVDHLDKKGQCALVHSALRGHSDILQYLLNCEWSAGPPQPGTLRKSQA
                     LQQALTAAASMGHSSVVQSLLGMAEEHEIEVNGTDTLWGETALTAAAGRGKVEICELL
                     LERGAAVSRANRRGVPPLFCAARQGHWQVVRLLLDRGCDVNLSDKQGRTPLMVASCEG
                     HLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAEIDQTDKNGRTP
                     LDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTAVVVTLLRKGAKLGN
                     AAWAMATSKPDILIILLQKLVEEGNVMYKKGKMKEAAQRYQYALRKFPREGLGEDMRP
                     FNELRVSLYLNLSRCRRKTNDFGLAEEFASKALELKPKSYEAFYARARAKRNSRQFLA
                     ALADLQEAVKLCPNNQEIKRLLARVEEECKQLQRNQQQKQQGPPPAPANDSDNEEDAP
                     ASSLKDHFPIEEAEEEDTSSQEESISPTPRSQPPPSVPSPYIRNLQEGLQSKGRSASP
                     QSRAGISKSLRETVAQSGLVMQPTKQAQIVKTNQHLGSGQSSMRNSSTKIQVSSQNPP
                     PSPMPGRVSAAPAVSRNQHLEGTGPFTAGTGCGHFGDRLGASQSLQLQRSESGTAYPL
                     PSKVKAAERLLAHASVAVDMAPPNQGGPVSCSDVRHPASLSSSGSSGSPSSSIKMSSS
                     TSSLTSSSSVSDGFKVQGPDSRIRDKGTTQVQGGTAEHRPRNTPFMGIMDKTARFQQQ
                     SNPPNRSWHCPVAEGLLTNTATAAGLQSNSEKPTLKPGGYCSQAKPCSVPPLSMGVHN
                     GAQVKELEENKCQIPALCQDNRITKGVPHLYPEGVSKQPLHVSTEAHRSHLTSAKPKR
                     SFIESNV"
     exon            185..373
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            374..478
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            479..609
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            610..796
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            797..1060
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            1061..1162
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            1163..1444
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            1445..1596
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            1597..1828
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            1829..1995
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            1996..2603
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            2604..2712
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            2713..2835
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            2836..3072
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            3073..3258
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            3259..3337
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            3338..3471
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            3472..3595
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            3596..3771
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            3772..3904
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            3905..3996
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            3997..4143
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            4144..4244
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     exon            4245..7763
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7248..7253
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /note="hexamer: AATAAA"
     polyA_site      7267
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /note="major polyA site"
     regulatory      7349..7354
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /note="hexamer: AGTAAA"
     polyA_site      7374
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
     regulatory      7674..7679
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
                     /note="hexamer: GATAAA"
     polyA_site      7695
                     /gene="Tanc1"
                     /gene_synonym="1200003E16Rik; mKIAA1728; Tanc"
ORIGIN      
        1 gagctgactg ttgggcacag aggaaggaca ggagagagag ctgagacata aggaccactg
       61 taccgcgttt cttccttcca tgaatgagaa gataccagag atagagacaa aagactgttg
      121 aaaatgctga aggctgtgct gaagaagagc cgagagggag gaaagggaag caagaaggaa
      181 gcaggaggtg actttggctc agagacgcct gccttgtcct ccagtggtga ctctcctgtg
      241 aacagtttgt ccacaacaga ggacacttat cgtgtgagct tggccaaagg ggtctctatg
      301 tctcttcctt catcaccttt gctgcctcga caatctctcc tgacacagtc aagatcgaac
      361 aaaaaatctc caggtcccgt caggaagccc aagtatgtgg aaagccccag ggtgccggga
      421 gatccagtta tgatcccgtt cggagaaggg tccaagccct cagagcccag tgcgactgaa
      481 gcgaaggctg ataatgaacc gagctgctct ccagcagctc aagaactgtt gacaaggctg
      541 ggatttctac tgggagaggg gatcccgagc gccacacaca taaccattga agacaaaaat
      601 gaagccatgt gcacagccct gagtcaaggc atcagccctt gttccacact cacaagcagc
      661 actgcctctc ccagcaccga cagcccctgc tcgaccttga atagctgtgt cagcaagacg
      721 gcagccagca aaagtccctg cgagaccatt agcagcccca gttccaccct ggaaagcaag
      781 gacagtggaa ttatagccac aatcacaagt tcatcggaaa atgatgaccg gagtggctcc
      841 agtctggaat ggaacagaga cggaagccta aggttagggg ttcagaaggg agtgcttcat
      901 gaccgaaggg cagataactg ttccccagtg gcagaagagg agactactgg gtccgcggag
      961 agcgtgctgc ccaaggcgga accctcagcc ggagatggtc cggtgcccta tcctcagagc
     1021 tctggctcgc tcataatgcc acggcccaac tcagttgcag cgacaagttc taccaaattg
     1081 gaagacttga gttatttgga cggacagaga aatgctcctc ttcggacatc aattagattg
     1141 ccctggcaca atacggctgg agcacggttt gctccctaca aacctcagga gatcctgttg
     1201 aagcccttgc tgtttgaagt accaagcatc acaactgact ctgtgtttgt gggaagagat
     1261 tggctctttc accagataga ggaaaacttg aggaacacag agctggcaga aaacagagga
     1321 gccgtggtcg tggggagcgt aggatttggg aagacagcca tcatttctaa gctggtggca
     1381 ctgagctgtc acggaagccg catgagacag atcgcatcca gcagtcccag tttgtcaccc
     1441 aaatcctcag atcccactca ggaccttcct ggtactccat tactctcacc aagttcttct
     1501 acaagtgctc tcagtgtgac cagaacacct gctgggcctg ggactgctga cagccagaga
     1561 ccgagagagg atgcggtgaa atacctcgct tctaaggtgg tggcctacca ttactgccag
     1621 gctgacaaca cttacacatg tctggtacct gagtttgtgc acagcattgc tgctttgctg
     1681 tgccggtccc accagctggc tgcctacaga gaccttctga tcaaggaacc ccagctgcag
     1741 agcatgctga gcctccgctc ctgtgtgcag gatcccgtgg ctgctttcaa gaggggcgtc
     1801 ctggagccac ttacaagcct aagaaacgag caaaaaattc cagaagagga gtatatcatc
     1861 cttatagatg gcttgaatga agctgagttt cataagcctg attacggaga tacgctgtct
     1921 tcgtttatta ccaaaattat tcctaagttc cccacctggc tgaagttgat cgtgaccgtg
     1981 agagcaaatt ttcaggaaat catcagtgca ctgccatttg tcaagctttc cctagacgac
     2041 tttccagaca acaaggacat tcacagtgac ctgcacgcct acgtccagca cagggtccac
     2101 agcagccagg acatcctcag caacatctcc ctgaatggca aggccgacgc cgccctcatc
     2161 agcaaagtca gcagccatct ggtgctgcgg agcctcggtt cctacctgta cctcaagctc
     2221 acgctggacc tcttccagcg gggccacctg gtcataaaga gtgccagcta caaggtggtg
     2281 cctgtgtctc tgtccgagct ctatctgctg cagtgtaaca tgaagttcat gacccagtct
     2341 gcctttgacc gggcccttcc cattttgaac gtggctcttg cgtccctcca ccccatgacg
     2401 gatgagcaga tatttcaggc tatcaacgcc ggccacatcc aaggcgagca gggctgggag
     2461 gacttccagc agaggatgga ggccctctct tgcttcctca ttaagaggag ggacaaaacc
     2521 cgcatgttct gccacccgtc cttcagagag tggctggtgt ggagagcgga tggcgaaagc
     2581 acagccttcc tgtgtgagcc caggaacgga cacgctctac tggcgttcat gttctctcga
     2641 caggagagca agctgaaccg ccagcagacc atggagcttg gccaccacat cctgaaggca
     2701 cacattttca agggcctcag taagaagact ggagtctcct caagccatct gcaggctctg
     2761 tggatcggtt acagcacaga ggggctgtct gctgccctgg cctctctcag gaatctctat
     2821 actcccaacg tgaaggtgag ccggctcctg attttgggag gggccaacgt gaactacagg
     2881 acagaagtgt taaacaatgc ccccatcctg tgcgtccagt ctcaccttgg ccatgaagaa
     2941 gttgtcactc tccttctgga atttggcgcc tgcctggatg ggatgtcgga gaacggtatg
     3001 aacgcactgt gctacgcagc tgctgccggc cacatgaagc tggtgtgtct gctcatcaag
     3061 aagggggcaa gggtggacca cttggataag aagggccagt gtgcactcgt ccacagcgca
     3121 ctgaggggcc acagtgacat tctccagtac ctgctgaact gtgagtggtc ggcaggccct
     3181 ccccagcctg gcaccctgag gaagagccaa gccctgcagc aggcactgac agccgccgcc
     3241 agcatgggcc acagctcggt cgtccagtcc ttgctgggaa tggcagagga acatgaaatc
     3301 gaagtcaacg gcaccgacac gttgtgggga gaaacagccc tgacggccgc tgctgggaga
     3361 ggaaaggtgg agatctgcga gctgctgctg gagcgtggag ctgccgtgtc tcgggccaac
     3421 aggagagggg ttccccctct gttttgtgcc gcccgccaag gccattggca ggttgtccga
     3481 ttgcttttgg atcgcggctg cgacgtgaac ctgagtgaca agcagggtcg aacacctctc
     3541 atggtggctt cctgtgaggg acacctgagc accgtggaat tcctcctctc aaaaggtgct
     3601 gctctttctt ccctggacaa agagggcctg tcagcattga gctgggcttg tctgaagggt
     3661 cacagggcag tggtccagta cctggtcgaa gaaggagcag agatagacca gacagacaaa
     3721 aacggccgta ctcccttgga cctggccgct ttctatggtg atgcagagac tgtgctgtat
     3781 ctggtggaga agggagccgt gatagaacat gtggaccaca gtgggatgcg ccccctggac
     3841 agagccatcg gctgtcgaaa cactgctgta gtggttaccc tgcttagaaa aggagccaaa
     3901 ctaggaaatg ccgcttgggc gatggccact tccaagcctg atattttgat tatacttttg
     3961 cagaaattgg tagaggaagg aaatgtgatg tacaagaaag ggaagatgaa ggaggcagcc
     4021 cagaggtacc agtatgcctt gcggaagttc cctcgggaag gactcggaga agacatgagg
     4081 ccgttcaatg aactgagagt ctccctctat ctcaatctgt cgcgatgccg aaggaaaaca
     4141 aacgactttg gtttggcaga agaatttgct tcaaaggctc tggaattgaa acccaaatcc
     4201 tacgaagcct tttatgcccg ggcgagagca aaaaggaaca gcaggcagtt cctggcagct
     4261 ctggctgacc tgcaagaggc tgtgaaactc tgtcccaaca atcaggaaat caagaggctc
     4321 ctggcccgtg ttgaagaaga gtgcaagcaa ctccagagga accagcagca aaagcagcag
     4381 ggtcccccac cagctccagc caatgactcg gataatgagg aggatgcgcc agcctctagt
     4441 ttaaaggacc acttccccat tgaggaggcg gaagaggaag acacctcttc acaggaagag
     4501 tccatttccc cgactcccag atcccagcca ccaccgtctg tcccttcccc atacatccgc
     4561 aaccttcaag agggattaca gtccaaaggc aggtcagcat ccccacagag cagggcagga
     4621 atcagcaagt ccctgagaga gactgtagcc cagtcaggct tggttatgca gcctaccaaa
     4681 caggcacaga tagtgaagac caaccaacat ctgggttccg ggcaatctag catgagaaac
     4741 agtagcacaa aaatacaagt ttcttctcag aaccctcccc cgagtccgat gccgggtaga
     4801 gtatctgcag cccctgccgt gagcagaaac cagcatttag agggaaccgg tcccttcact
     4861 gcaggaactg gttgtggcca cttcggggat cggctgggcg ccagccagag cctccagctg
     4921 cagcgcagtg agagcggcac tgcgtatcct ctaccgagca aagtcaaagc tgccgagagg
     4981 ctcctggctc atgcctccgt ggccgtggac atggctcctc caaaccaggg cggaccagtg
     5041 agctgtagcg atgtgcggca cccggcttcc ctctctagct caggctcctc tggctctcca
     5101 tcgagcagca taaagatgtc aagttccacc agtagtttga cttcaagcag tagcgtttca
     5161 gacggattca aggtccaagg accagactct cggatcagag acaaaggtac aacccaggtg
     5221 cagggtggca ctgccgaaca caggccccgc aacactccat ttatgggcat catggacaag
     5281 accgccaggt tccagcagca aagcaatcct ccgaaccgct cctggcactg cccggtggca
     5341 gaggggctac tgacaaacac agccactgca gctggcctgc agtctaactc tgagaaaccc
     5401 actctcaagc caggaggata ctgtagccaa gccaaaccgt gttcagttcc tcccctgagc
     5461 atgggtgtcc acaatggggc tcaggtgaag gagctggaag agaacaagtg ccaaatccca
     5521 gccctctgtc aagataacag gataactaag ggggttcctc atctctaccc agagggcgtc
     5581 tctaagcagc cacttcatgt cagtacggaa gcccacagga gccacctcac ttcagcaaaa
     5641 ccaaagcgat cgttcataga gtccaatgtg tgagccttaa gcaacccctg tgtagaatct
     5701 ggaggcagtc tgttggctcg tggtaataaa tgatgtctct ttttcttttc ataataaaaa
     5761 ttacatgtta gccatatttt ccacctcttg ggtggatctg atgccattga catattaaaa
     5821 ctgtaggata aaactataat tagtagctag aaatcagcca taaacagaag tactaaacag
     5881 cattgaacac tgttgtcagc ttatatctgg cgatttaaag gctgccaaga agacatcaac
     5941 tgatgccgtt ctcttaggag attatttggc ttgctctgtg taaaagcaca cgtacttaga
     6001 gaaggaaaaa aaaatccact ggtaaaagtt aactcctgac ataatatctg gaaaattctg
     6061 gaaaagatgg ggagggaggg tgtttaagtt acagatccct aagtcaaacc tgtccttaca
     6121 tgtgtgtaaa aatcgcaacc tgagtgattt ctagctggat ataaatgtga cttttatctg
     6181 caaaatacaa gcgcagccaa gtatcttgtt ggttcctcga gaggatcaaa cacctacttc
     6241 catgatatgg tgaattgaag agtattttta tagccccctt tttggaacta tacttaggtt
     6301 tcaccgtgtt gctgataaga cgagaacagg ctagctagaa tttggattgg tgtccaggtc
     6361 agagttgtgc aaaagtacca agagaagcac tcttagtgac ggccacaaat tagctctaac
     6421 tggttccgaa agtgttctgg acagtgacgg tccccaaaac aagcctctaa tgtcctctag
     6481 ggaaagtgtt cagacaggac ccttgaggtc tgggtggcag ttttgatttc cttacacagc
     6541 ccgttgtttc atagtcatgt gtcatatata tatataaata gctagcccat tttattcaga
     6601 cttgtaaata actcaaagga agttaatcta aagacaaata acagaacccc gccatctctc
     6661 tgcatgttct ctgtacgctc catcatgctg gttgccgcac tgaacgatgc gttatcacgg
     6721 cttgtaacag tatacccgca atggcacttt atctcctgtg tatggacacc tctgaggtgc
     6781 tacttaaatc cgagtgacat atttttcacc tgtaaagata aggtacaggg atgaaccttg
     6841 gcttaaggta tttttatatg aaaatggtgt tattggaaga tgttcaaatg ctggtttgag
     6901 agaggtggga gaagtatttt atatgttgag atgtgaaatg tattttctag aatcggggag
     6961 aaggaagttc tatatttgca gaatgtttta aacgtgagta cccacgatgc tcctatgaac
     7021 atcattaagg ttttgtacga aaaggaacct tgccgcggcg tcatttagtg tgtctgttcc
     7081 tgtgtgcaga gggctttgta caaacagcta ggccgttttt ataagctctc tctgagttct
     7141 gctccagtta ctatggctta tttattgttt tccttaatat ttgtgacagt cttactcttt
     7201 cgttatgtag tttgtttctg cacaactact gtactttttc cacatggaat aaaaaccatt
     7261 actccaagtg ggttggcatt cattgctcag cgggtaagaa ggcagggaca cctctcgtgg
     7321 ctctctgcct tgatttgtca ccctaaggag taaaaagcac tttgaataca ccaacagcac
     7381 gggttttatt ttaatttcag aataaggtgg gagcttctag aaattccaaa gtactctagt
     7441 ctcatgattt tttttgcctt aaataggaaa aatgcacggg acgagcagtg tggactaatg
     7501 ggtctcgctg gtcacagata cttgtaccct gtaaccgcca gtgcaccgtg ccctctcagg
     7561 acagctgcgt cttccagcac atttgcagtg tcttctcatt gaaactgtct gtctttatga
     7621 ccacagattt gtctcaaact gtgtaagaat agagattgtt ttggttgtat catgataaaa
     7681 ttcttacttg aagtatttta tatttatata tttttcattt aaaagatttc gaaacttccc
     7741 aaatgcatac tgtattcacc ctg
//
