LOCUS       NM_147155               2358 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus T cell activation GTPase activating protein 1
            (Tagap1), mRNA.
ACCESSION   NM_147155 NM_028271
VERSION     NM_147155.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2358)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2358)
  AUTHORS   Church,D.M., Goodstadt,L., Hillier,L.W., Zody,M.C., Goldstein,S.,
            She,X., Bult,C.J., Agarwala,R., Cherry,J.L., DiCuccio,M.,
            Hlavina,W., Kapustin,Y., Meric,P., Maglott,D., Birtle,Z.,
            Marques,A.C., Graves,T., Zhou,S., Teague,B., Potamousis,K.,
            Churas,C., Place,M., Herschleb,J., Runnheim,R., Forrest,D.,
            Amos-Landgraf,J., Schwartz,D.C., Cheng,Z., Lindblad-Toh,K.,
            Eichler,E.E. and Ponting,C.P.
  CONSRTM   Mouse Genome Sequencing Consortium
  TITLE     Lineage-specific biology revealed by a finished genome assembly of
            the mouse
  JOURNAL   PLoS Biol 7 (5), e1000112 (2009)
   PUBMED   19468303
REFERENCE   3  (bases 1 to 2358)
  AUTHORS   Ruan,Y., Sensen,C.W. and van der Hoorn,F.A.
  TITLE     A novel group of multi-GAP-domain proteins
  JOURNAL   Mol Reprod Dev 75 (10), 1578-1589 (2008)
   PUBMED   18363199
REFERENCE   4  (bases 1 to 2358)
  AUTHORS   Bauer,H., Willert,J., Koschorz,B. and Herrmann,B.G.
  TITLE     The t complex-encoded GTPase-activating protein Tagap1 acts as a
            transmission ratio distorter in mice
  JOURNAL   Nat Genet 37 (9), 969-973 (2005)
   PUBMED   16116428
REFERENCE   5  (bases 1 to 2358)
  AUTHORS   VanBuren,V., Piao,Y., Dudekula,D.B., Qian,Y., Carter,M.G.,
            Martin,P.R., Stagg,C.A., Bassey,U.C., Aiba,K., Hamatani,T.,
            Kargul,G.J., Luo,A.G., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Assembly, verification, and initial annotation of the NIA mouse
            7.4K cDNA clone set
  JOURNAL   Genome Res 12 (12), 1999-2003 (2002)
   PUBMED   12466305
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AV444953.1, BQ555561.1 and AC122413.4.
            
            On May 23, 2007 this sequence version replaced NM_147155.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript from the same
            strain was available for the full length of the gene. The extent of
            this transcript is supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AI006630.1, BI656583.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-209               AV444953.1         45-253
            210-807             BQ555561.1         85-682
            808-2358            AC122413.4         133972-135522
FEATURES             Location/Qualifiers
     source          1..2358
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 4.55 cM"
     gene            1..2358
                     /gene="Tagap1"
                     /gene_synonym="2610315E15Rik; FKSG15"
                     /note="T cell activation GTPase activating protein 1"
                     /db_xref="GeneID:380608"
                     /db_xref="MGI:MGI:1919786"
     exon            1..129
                     /gene="Tagap1"
                     /gene_synonym="2610315E15Rik; FKSG15"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..1545
                     /gene="Tagap1"
                     /gene_synonym="2610315E15Rik; FKSG15"
                     /codon_start=1
                     /product="T-cell activation GTPase-activating protein 1"
                     /protein_id="NP_671511.2"
                     /db_xref="CCDS:CCDS49940.1"
                     /db_xref="GeneID:380608"
                     /db_xref="MGI:MGI:1919786"
                     /translation="MAATTAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLA
                     LEEQEKVEVKILVEFLIDNCFEIFGENIRTRSRITSDDSLEHTDSSDVSTLQNDSAYD
                     SNDPDVEPTSGAASPNRQLEGPTPTMAGLDTRGHRDTCESSSESSVSMVVRLKNSIVQ
                     QDRRFSEPNMSPSRECLVGPTSKQKLTRSEDSFTLSQDASCSEGDEAEDPFTEEVFPA
                     VDSKPKRPVDLKIKNWTQGLASPQGHITKAFSRSSPGESLGSSPVPSPSCPKRNFFTR
                     HQSFTTKTDKTKPQREIRKHSMLFSFASHKKVLPRTSSIGSEKSKDFSRDQLQKDLRK
                     ESQLSGRIVQENESEIQSQTSLGFSLSGTWALSVDNTFQLVDMRKPGSPPSYEEAIYY
                     QTSGLTAYGGQTVGSMRSRMFKPSTAVPPVPSHHGGDLSEGTPGGHRLSSVTEHWTHS
                     QTVHVSIETQGRSELHQLRTVSESMQKAKLDCLGPQHSHLVFEADQLCCARESYI"
     exon            130..183
                     /gene="Tagap1"
                     /gene_synonym="2610315E15Rik; FKSG15"
                     /inference="alignment:Splign:2.1.0"
     exon            184..298
                     /gene="Tagap1"
                     /gene_synonym="2610315E15Rik; FKSG15"
                     /inference="alignment:Splign:2.1.0"
     exon            299..2358
                     /gene="Tagap1"
                     /gene_synonym="2610315E15Rik; FKSG15"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2289..2294
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tagap1"
                     /gene_synonym="2610315E15Rik; FKSG15"
                     /note="hexamer: AATAAA"
     polyA_site      2312
                     /gene="Tagap1"
                     /gene_synonym="2610315E15Rik; FKSG15"
                     /note="major polyA site"
ORIGIN      
        1 cttgggtggt tgtcttggag aagcaagatg gcggcgacta ccgccgcggt ggtggccgag
       61 gaagacacgg agctgcgcga cctgctggtg cagacgctgg agaacagcgg cgtgctgaac
      121 cgcatcaagg ctgaactcag agcggctgtg tttttagcac tagaagaaca agaaaaagta
      181 gaggttaaga tcttggtgga attcctcatc gacaactgct ttgagatatt tggggagaac
      241 attcggacgc gttcccgcat cacttctgac gactccctgg aacacactga cagttcagac
      301 gtgtcaactc tgcagaatga ctcggcctat gacagcaatg acccagatgt ggagcccaca
      361 agtggcgcag cctctcccaa caggcaactg gagggtccca ctcccacaat ggctggtctg
      421 gatacccggg gccaccggga cacctgtgag tcaagctcag agtccagcgt tagcatggta
      481 gtcaggctga aaaactccat tgtccaacaa gacaggcggt tctctgaacc caacatgtca
      541 ccctcacgag agtgcctcgt gggcccaaca tccaagcaaa agctaacaag gagtgaggac
      601 agcttcactc tgtcccagga cgcctcctgt tctgaaggcg atgaagctga agatcccttt
      661 acagaggaag tcttcccagc agtggacagc aaacccaaga gacctgtgga tttgaaaata
      721 aagaattgga cccaaggttt agcatctcca cagggacaca taaccaaagc tttctccaga
      781 tcctccccag gcgaatcttt gggcagctca cctgtgcctt ctccatcctg ccccaagaga
      841 aacttcttca ccagacacca gagtttcaca acaaagacag acaaaaccaa accccagaga
      901 gaaattagaa agcactccat gttgttttcc tttgcgtctc acaagaaagt gctgccccga
      961 acctccagca ttgggtctga gaaatccaaa gacttttcta gagaccaact ccagaaggac
     1021 ttgaggaaag agagccaact ttctggcaga atcgtccagg aaaatgagtc agaaatccaa
     1081 agccaaacat ctttgggctt cagcttgtct ggcacctggg ccctctcagt cgacaacacg
     1141 ttccagttag tggatatgag gaaaccagga agcccaccat cttacgaaga ggccatttat
     1201 taccagacat caggactcac agcctacggt ggccagacag ttgggagtat gaggtcaaga
     1261 atgttcaagc caagcacagc ggtgccccct gtgccttctc accatggagg tgacctcagt
     1321 gaagggacac ctggtggaca cagattgtct tctgtgactg agcactggac acacagtcag
     1381 actgtccatg tctctataga aactcagggg agatctgagc tacaccagtt gaggacagtg
     1441 tccgagtcca tgcagaaggc taagctggac tgtcttgggc cacaacacag ccacttagtc
     1501 tttgaggctg accaactctg ctgtgctaga gaatcctaca tttaagaaag ccttgtacca
     1561 tggctaactt gtgtgtgaag atgcgactgc agagaactgt ctgttgagtc acagataagc
     1621 tcattcagaa ctcagtgtgc ggctctcctc tgtgaggatg gctcacatgg tgacaccaaa
     1681 ttttgcctgt gtgtaaccgg gtttgtgcaa tatgtagtaa atgtataaaa tgtattatta
     1741 tatgcaaggt attagatgca aagggtgtct gcgtacatcc cttcatgcat gcacttctgt
     1801 atgttgtttt tttgtcctca ggcacttgtt tctattaagt agaaagagtt ttacttttct
     1861 taatgttaca gcaaatgtca tgcctgtgtt cacattagcc gccagctgca tgtaggtgga
     1921 aatgtctgag cctctgatgc atcttctcct aagcaggctt gagacgagtc agcatcatag
     1981 aagggaacag actgaaagac actgtacttg gtgtgtgacc catcagccgc actgggagaa
     2041 ggtctttcag tcatctaatg gaatgtgggt ggcctggtgg aaatgcattc tgtcagtagt
     2101 aactcacgca gagtactttg agcctctgca gctcagtcat gtcttgtgca gctgtgtagt
     2161 ggtaagcact gttgtatgca ttggggagtc ttgtataaga cttcagtaga gtttatttat
     2221 tagtcacaat aaactgccct cctcctttag acagtttatt acttgccgat gttatatcct
     2281 ttgcctcaaa taaaaatcca ccaagaacat tatccacaca ctgttccatt cagccagtgt
     2341 ctgttcacta tacactca
//
