LOCUS       NM_028958               1935 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus TATA-box binding protein associated factor 7 like
            (Taf7l), mRNA.
ACCESSION   NM_028958
VERSION     NM_028958.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1935)
  AUTHORS   Ling,L., Li,F., Yang,P., Oates,R.D., Silber,S., Kurischko,C.,
            Luca,F.C., Leu,N.A., Zhang,J., Yue,Q., Skaletsky,H., Brown,L.G.,
            Rozen,S.G., Page,D.C., Wang,P.J. and Zheng,K.
  TITLE     Genetic characterization of a missense mutation in the X-linked
            TAF7L gene identified in an oligozoospermic mandagger
  JOURNAL   Biol Reprod 107 (1), 157-167 (2022)
   PUBMED   35554494
  REMARK    GeneRIF: The mouse D144G substitution is analogous to a missense
            mutation (D136G) in the X-linked TAF7L gene identified in
            oligozoospermic men. Although the D144G substitution in mouse does
            not affect male fertility, RNA-seq analyses revealed alterations in
            transcriptome profiles in the Taf7l (D144G) mutant testes.
REFERENCE   2  (bases 1 to 1935)
  AUTHORS   He,Y., Chen,Q., Dai,J., Cui,Y., Zhang,C., Wen,X., Li,J., Xiao,Y.,
            Peng,X., Liu,M., Shen,B., Sha,J., Hu,Z., Li,J. and Shu,W.
  TITLE     Single-cell RNA-Seq reveals a highly coordinated transcriptional
            program in mouse germ cells during primordial follicle formation
  JOURNAL   Aging Cell 20 (7), e13424 (2021)
   PUBMED   34174788
REFERENCE   3  (bases 1 to 1935)
  AUTHORS   Gustafson,E.A., Seymour,K.A., Sigrist,K., Rooij,D.G.D.E. and
            Freiman,R.N.
  TITLE     ZFP628 Is a TAF4b-Interacting Transcription Factor Required for
            Mouse Spermiogenesis
  JOURNAL   Mol Cell Biol 40 (7), e00228-19 (2020)
   PUBMED   31932482
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1935)
  AUTHORS   Li,J.Y., Liu,Y.F., Xu,H.Y., Zhang,J.Y., Lv,P.P., Liu,M.E.,
            Ying,Y.Y., Qian,Y.Q., Li,K., Li,C., Huang,Y., Xu,G.F., Ding,G.L.,
            Mao,Y.C., Xu,C.M., Liu,X.M., Sheng,J.Z., Zhang,D. and Huang,H.F.
  TITLE     Basonuclin 1 deficiency causes testicular premature aging: BNC1
            cooperates with TAF7L to regulate spermatogenesis
  JOURNAL   J Mol Cell Biol 12 (1), 71-83 (2020)
   PUBMED   31065688
REFERENCE   5  (bases 1 to 1935)
  AUTHORS   Horiuchi,K., Perez-Cerezales,S., Papasaikas,P., Ramos-Ibeas,P.,
            Lopez-Cardona,A.P., Laguna-Barraza,R., Fonseca Balvis,N.,
            Pericuesta,E., Fernandez-Gonzalez,R., Planells,B., Viera,A.,
            Suja,J.A., Ross,P.J., Alen,F., Orio,L., Rodriguez de Fonseca,F.,
            Pintado,B., Valcarcel,J. and Gutierrez-Adan,A.
  TITLE     Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12
            Intron Splicing-Defective Zrsr1 Mutant Mice
  JOURNAL   Cell Rep 23 (1), 143-155 (2018)
   PUBMED   29617656
REFERENCE   6  (bases 1 to 1935)
  AUTHORS   Cheng,Y., Buffone,M.G., Kouadio,M., Goodheart,M., Page,D.C.,
            Gerton,G.L., Davidson,I. and Wang,P.J.
  TITLE     Abnormal sperm in mice lacking the Taf7l gene
  JOURNAL   Mol Cell Biol 27 (7), 2582-2589 (2007)
   PUBMED   17242199
  REMARK    GeneRIF: While spermatogenesis was completed in Taf7l(-/Y) mice,
            the weight of Taf7l(-/Y) testis decreased. Mutant epididymal sperm
            exhibited abnormal morphology. Sperm motility was significantly
            reduced, and Taf7l(-/Y) males were fertile with reduced litter
            size.
            GeneRIF: Disruption of Taf7l causes reduced testis weight,
            decreased sperm production and motility, and abnormal morphology
REFERENCE   7  (bases 1 to 1935)
  AUTHORS   Wang,P.J., Page,D.C. and McCarrey,J.R.
  TITLE     Differential expression of sex-linked and autosomal
            germ-cell-specific genes during spermatogenesis in the mouse
  JOURNAL   Hum Mol Genet 14 (19), 2911-2918 (2005)
   PUBMED   16118233
  REMARK    GeneRIF: Genes expressed in germ cells, like Taf7l (Taf2q), are
            subject to meiotic sex-chromosome inactivation (MSCI) during
            spermatogenesis.
REFERENCE   8  (bases 1 to 1935)
  AUTHORS   Catena,R., Argentini,M., Martianov,I., Parello,C., Brancorsini,S.,
            Parvinen,M., Sassone-Corsi,P. and Davidson,I.
  TITLE     Proteolytic cleavage of ALF into alpha- and beta-subunits that form
            homologous and heterologous complexes with somatic TFIIA and TRF2
            in male germ cells
  JOURNAL   FEBS Lett 579 (16), 3401-3410 (2005)
   PUBMED   15927180
REFERENCE   9  (bases 1 to 1935)
  AUTHORS   Pointud,J.C., Mengus,G., Brancorsini,S., Monaco,L., Parvinen,M.,
            Sassone-Corsi,P. and Davidson,I.
  TITLE     The intracellular localisation of TAF7L, a paralogue of
            transcription factor TFIID subunit TAF7, is developmentally
            regulated during male germ-cell differentiation
  JOURNAL   J Cell Sci 116 (Pt 9), 1847-1858 (2003)
   PUBMED   12665565
  REMARK    GeneRIF: TAF7L replaces TAF7 as a TFIID subunit in late pachytene
            spermatocytes and in haploid cells.
REFERENCE   10 (bases 1 to 1935)
  AUTHORS   Wang,P.J., McCarrey,J.R., Yang,F. and Page,D.C.
  TITLE     An abundance of X-linked genes expressed in spermatogonia
  JOURNAL   Nat Genet 27 (4), 422-426 (2001)
   PUBMED   11279525
  REMARK    GeneRIF: Taf7l (Taf2q) is a gene that is expressed in testis that
            was identified in a genome-wide cDNA subtraction screen.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB871901.1, AK017109.1 and AW553087.2.
            
            On Jan 5, 2010 this sequence version replaced NM_028958.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK017109.1, AF285574.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-59                BB871901.1         2-60
            60-1932             AK017109.1         61-1933
            1933-1935           AW553087.2         1-3                 c
FEATURES             Location/Qualifiers
     source          1..1935
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 56.18 cM"
     gene            1..1935
                     /gene="Taf7l"
                     /gene_synonym="4933438I11Rik; Taf2q"
                     /note="TATA-box binding protein associated factor 7 like"
                     /db_xref="GeneID:74469"
                     /db_xref="MGI:MGI:1921719"
     exon            1..300
                     /gene="Taf7l"
                     /gene_synonym="4933438I11Rik; Taf2q"
                     /inference="alignment:Splign:2.1.0"
     CDS             15..1430
                     /gene="Taf7l"
                     /gene_synonym="4933438I11Rik; Taf2q"
                     /note="TATA box binding protein (TBP)-associated factor,
                     RNA polymerase II, Q; TATA box binding protein-associated
                     factor RNA polymerase II subunit Q; TAF7-like RNA
                     polymerase II, TATA box binding protein (TBP)-associated
                     factor; TATA box-binding protein-associated factor 50 kDa;
                     transcription initiation factor TFIID 50 kDa subunit"
                     /codon_start=1
                     /product="transcription initiation factor TFIID subunit
                     7-like"
                     /protein_id="NP_083234.2"
                     /db_xref="CCDS:CCDS53184.1"
                     /db_xref="GeneID:74469"
                     /db_xref="MGI:MGI:1921719"
                     /translation="MERGEEAPTEGAPPEGALVEAKAPVIPEAPATDVSTTEEAGSKE
                     PQVPSGPRPEGAGDTCDTRGARGPPTPGRAKSQKTPRQGTARCQTLESAMRSMSVRLE
                     CHDVEEQFILRLPPEQAYAVRKIIHSRNAAWKDKLKIDFSPDGHHAVVQVDNVSLPAK
                     LVNLPCVIGSLKTIDRKTFYKTADVSQMLVCSPEGEPHSPPEEPVVSTGPTVIGISEG
                     KAERKKYNWKHGITPPLKNVRKKRFRKTTKKLPDVKQVDEINFSEYTQSPSVEKEVKR
                     LLYSDAEAVSVRWEVVDDDDAKEIESQGSMPTTPGISQMGGASLSDYDVFREMMGDSG
                     SNSNDVEEKSNEGDDDDDEDEDDEDYGNEKEEEETDNSEEELEKELQAKFNEFSLHEA
                     DQDYSSITMAIQKLIFIKEKRLQMIYKKAQRQKELLRKVENLTLKRHFQNVLGKLNIM
                     EKEKCEQIYHLQEQLKCFLKE"
     exon            301..362
                     /gene="Taf7l"
                     /gene_synonym="4933438I11Rik; Taf2q"
                     /inference="alignment:Splign:2.1.0"
     exon            363..441
                     /gene="Taf7l"
                     /gene_synonym="4933438I11Rik; Taf2q"
                     /inference="alignment:Splign:2.1.0"
     exon            442..575
                     /gene="Taf7l"
                     /gene_synonym="4933438I11Rik; Taf2q"
                     /inference="alignment:Splign:2.1.0"
     exon            576..705
                     /gene="Taf7l"
                     /gene_synonym="4933438I11Rik; Taf2q"
                     /inference="alignment:Splign:2.1.0"
     exon            706..761
                     /gene="Taf7l"
                     /gene_synonym="4933438I11Rik; Taf2q"
                     /inference="alignment:Splign:2.1.0"
     exon            762..803
                     /gene="Taf7l"
                     /gene_synonym="4933438I11Rik; Taf2q"
                     /inference="alignment:Splign:2.1.0"
     exon            804..876
                     /gene="Taf7l"
                     /gene_synonym="4933438I11Rik; Taf2q"
                     /inference="alignment:Splign:2.1.0"
     exon            877..978
                     /gene="Taf7l"
                     /gene_synonym="4933438I11Rik; Taf2q"
                     /inference="alignment:Splign:2.1.0"
     exon            979..1212
                     /gene="Taf7l"
                     /gene_synonym="4933438I11Rik; Taf2q"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..1325
                     /gene="Taf7l"
                     /gene_synonym="4933438I11Rik; Taf2q"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1385
                     /gene="Taf7l"
                     /gene_synonym="4933438I11Rik; Taf2q"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1935
                     /gene="Taf7l"
                     /gene_synonym="4933438I11Rik; Taf2q"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1913..1918
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Taf7l"
                     /gene_synonym="4933438I11Rik; Taf2q"
                     /note="hexamer: AATAAA"
     polyA_site      1933
                     /gene="Taf7l"
                     /gene_synonym="4933438I11Rik; Taf2q"
                     /note="major polyA site"
ORIGIN      
        1 aagtattctg agtcatggag cgcggcgagg aagcacccac tgagggagct ccgcctgagg
       61 gggctttggt ggaggccaaa gcccccgtta ttcctgaagc ccccgctaca gatgtttcga
      121 caaccgaaga agcgggctcc aaagagcccc aggtcccttc cggccctcgt cccgaaggtg
      181 ctggggacac ttgtgacacc cgaggggctc gaggcccacc gactcccggc agggccaagt
      241 ctcagaagac cccccgccag ggcactgctc gctgccagac cctcgagagt gccatgcgat
      301 ccatgagtgt aaggcttgaa tgtcatgacg ttgaggaaca gtttatattg cgtctgcctc
      361 cggaacaagc ttatgctgtc aggaaaatta tacattctag aaatgctgct tggaaggata
      421 aactaaaaat tgacttttct cctgatggcc accatgcggt tgttcaagta gacaacgtct
      481 cactgcctgc taaactggtt aatctgcctt gtgttatcgg aagcctgaaa actattgaca
      541 gaaagacatt ttataagacc gcggatgttt ctcagatgct tgtatgcagt cctgaaggtg
      601 agcctcattc tcctcctgaa gaaccagttg tctctactgg tcctactgta attggaatta
      661 gtgaagggaa ggcagagaga aaaaaatata actggaagca tggcattact ccaccactta
      721 agaatgtcag aaagaaaagg ttccggaaaa caacaaaaaa gctcccagat gtgaaacaag
      781 tggatgaaat caactttagt gagtacactc aatctccaag tgtggaaaaa gaagtgaaga
      841 gactgctcta ctcagatgct gaagctgtca gtgtccgctg ggaagtcgtt gatgatgatg
      901 atgctaagga aatagaaagt caagggtcca tgccaaccac tccaggaatc tcacagatgg
      961 gtggtgctag tttatcagac tatgatgtgt ttcgggagat gatgggtgat tctggcagca
     1021 acagtaatga tgtggaagag aagagtaatg aaggtgacga cgatgatgat gaagatgaag
     1081 atgatgaaga ctatggaaat gaaaaggagg aggaagagac agacaattct gaagaggagt
     1141 tagagaagga gctgcaggcc aaatttaatg aatttagcct ccatgaagca gaccaagatt
     1201 acagttcaat aaccatggca attcagaaac tgatttttat caaagaaaag aggctccaga
     1261 tgatttataa aaaagcccag cgacagaagg aactcctcag gaaagtggaa aacttgaccc
     1321 tcaagagaca tttccagaat gttttgggga agcttaacat aatggaaaaa gagaagtgtg
     1381 aacagattta tcacctccag gaacaactga aatgtttcct gaaggagtaa ggaaagcctc
     1441 agcctggcac accaagtgga ttcaccctcc agatgaagac tgggtggaac cacatacttc
     1501 tgtccctcta ctttatctta aacaactttt atttgttgag catttttcac taaagtaaat
     1561 ttaaggatca catttatata ggagacatat atagagggag ttatataaat gcataggttt
     1621 agagacccac atgggatgtt gtttctcttt gtcaatttga gattaaatgt gtgtatttct
     1681 ttatctctta ctctatggta ccatgagatc attcagccgt ccttgtcaaa ggtttaggct
     1741 agaaagatac acagctgttt tacataagtt tacttttcaa acctggtttt aagtatttct
     1801 tacaattttg aaaatgatca aattgtcagc tggcaatccc agcaatttaa aaggcagaag
     1861 cagaaggtca aattgaaggc cagcctgggc tgtatataag accctgtctc aaaataaaat
     1921 aaactgaaaa ccatg
//
