LOCUS       NM_133966               2990 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus TATA-box binding protein associated factor 5 like
            (Taf5l), transcript variant 1, mRNA.
ACCESSION   NM_133966
VERSION     NM_133966.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2990)
  AUTHORS   Seruggia,D., Oti,M., Tripathi,P., Canver,M.C., LeBlanc,L., Di
            Giammartino,D.C., Bullen,M.J., Nefzger,C.M., Sun,Y.B.Y.,
            Farouni,R., Polo,J.M., Pinello,L., Apostolou,E., Kim,J., Orkin,S.H.
            and Das,P.P.
  TITLE     TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via
            the MYC Regulatory Network
  JOURNAL   Mol Cell 74 (6), 1148-1163 (2019)
   PUBMED   31005419
  REMARK    GeneRIF: TAF5L and TAF6L maintain self-renewal of embryonic stem
            cells via the MYC regulatory network.
REFERENCE   2  (bases 1 to 2990)
  AUTHORS   Bardot,P., Vincent,S.D., Fournier,M., Hubaud,A., Joint,M., Tora,L.
            and Pourquie,O.
  TITLE     The TAF10-containing TFIID and SAGA transcriptional complexes are
            dispensable for early somitogenesis in the mouse embryo
  JOURNAL   Development 144 (20), 3808-3818 (2017)
   PUBMED   28893950
REFERENCE   3  (bases 1 to 2990)
  AUTHORS   Nagy,Z., Riss,A., Romier,C., le Guezennec,X., Dongre,A.R.,
            Orpinell,M., Han,J., Stunnenberg,H. and Tora,L.
  TITLE     The human SPT20-containing SAGA complex plays a direct role in the
            regulation of endoplasmic reticulum stress-induced genes
  JOURNAL   Mol Cell Biol 29 (6), 1649-1660 (2009)
   PUBMED   19114550
REFERENCE   4  (bases 1 to 2990)
  AUTHORS   Zhao,Y., Lang,G., Ito,S., Bonnet,J., Metzger,E., Sawatsubashi,S.,
            Suzuki,E., Le Guezennec,X., Stunnenberg,H.G., Krasnov,A.,
            Georgieva,S.G., Schule,R., Takeyama,K., Kato,S., Tora,L. and
            Devys,D.
  TITLE     A TFTC/STAGA module mediates histone H2A and H2B deubiquitination,
            coactivates nuclear receptors, and counteracts heterochromatin
            silencing
  JOURNAL   Mol Cell 29 (1), 92-101 (2008)
   PUBMED   18206972
REFERENCE   5  (bases 1 to 2990)
  AUTHORS   Nagy,Z. and Tora,L.
  TITLE     Distinct GCN5/PCAF-containing complexes function as co-activators
            and are involved in transcription factor and global histone
            acetylation
  JOURNAL   Oncogene 26 (37), 5341-5357 (2007)
   PUBMED   17694077
  REMARK    Review article
REFERENCE   6  (bases 1 to 2990)
  AUTHORS   Martinez,E., Palhan,V.B., Tjernberg,A., Lymar,E.S., Gamper,A.M.,
            Kundu,T.K., Chait,B.T. and Roeder,R.G.
  TITLE     Human STAGA complex is a chromatin-acetylating transcription
            coactivator that interacts with pre-mRNA splicing and DNA
            damage-binding factors in vivo
  JOURNAL   Mol Cell Biol 21 (20), 6782-6795 (2001)
   PUBMED   11564863
REFERENCE   7  (bases 1 to 2990)
  AUTHORS   Brand,M., Moggs,J.G., Oulad-Abdelghani,M., Lejeune,F.,
            Dilworth,F.J., Stevenin,J., Almouzni,G. and Tora,L.
  TITLE     UV-damaged DNA-binding protein in the TFTC complex links DNA damage
            recognition to nucleosome acetylation
  JOURNAL   EMBO J 20 (12), 3187-3196 (2001)
   PUBMED   11406595
REFERENCE   8  (bases 1 to 2990)
  AUTHORS   Brand,M., Yamamoto,K., Staub,A. and Tora,L.
  TITLE     Identification of TATA-binding protein-free TAFII-containing
            complex subunits suggests a role in nucleosome acetylation and
            signal transduction
  JOURNAL   J Biol Chem 274 (26), 18285-18289 (1999)
   PUBMED   10373431
REFERENCE   9  (bases 1 to 2990)
  AUTHORS   Schiltz,R.L., Mizzen,C.A., Vassilev,A., Cook,R.G., Allis,C.D. and
            Nakatani,Y.
  TITLE     Overlapping but distinct patterns of histone acetylation by the
            human coactivators p300 and PCAF within nucleosomal substrates
  JOURNAL   J Biol Chem 274 (3), 1189-1192 (1999)
   PUBMED   9880483
REFERENCE   10 (bases 1 to 2990)
  AUTHORS   Ogryzko,V.V., Kotani,T., Zhang,X., Schiltz,R.L., Howard,T.,
            Yang,X.J., Howard,B.H., Qin,J. and Nakatani,Y.
  TITLE     Histone-like TAFs within the PCAF histone acetylase complex
  JOURNAL   Cell 94 (1), 35-44 (1998)
   PUBMED   9674425
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB852568.1, AK089463.1, AK033477.1 and AI849020.1.
            
            On Oct 25, 2017 this sequence version replaced NM_133966.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC013550.1, SRR1660817.198721.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-9                 BB852568.1         2-10
            10-1892             AK089463.1         2-1884
            1893-2523           AK033477.1         1833-2463
            2524-2990           AI849020.1         1-467               c
FEATURES             Location/Qualifiers
     source          1..2990
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 72.31 cM"
     gene            1..2990
                     /gene="Taf5l"
                     /gene_synonym="1110005N04Rik"
                     /note="TATA-box binding protein associated factor 5 like"
                     /db_xref="GeneID:102162"
                     /db_xref="MGI:MGI:1919039"
     exon            1..209
                     /gene="Taf5l"
                     /gene_synonym="1110005N04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            210..354
                     /gene="Taf5l"
                     /gene_synonym="1110005N04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            355..459
                     /gene="Taf5l"
                     /gene_synonym="1110005N04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            460..1184
                     /gene="Taf5l"
                     /gene_synonym="1110005N04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1185..2981
                     /gene="Taf5l"
                     /gene_synonym="1110005N04Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2905..2910
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Taf5l"
                     /gene_synonym="1110005N04Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2929
                     /gene="Taf5l"
                     /gene_synonym="1110005N04Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggcggcgtcg cgcgtccgcg gcctagcccg gcgtgcccgc tccgtcaggc ggtcatgggg
       61 cggccaccga gaaccgcgag cgcgggagga cgtagggcgc ggggacccgg ctagccggtc
      121 gtcgtacgga gtcctacggc gggcaaccga tacggaagca gccggtgccg gggcggcggc
      181 ggggcagcgg gagccgcctg ggatgttcag tcatgaaacg agtgcgcacg gagcaggttc
      241 aggtggcagt gtcctgctac ctcaaacgcc ggcagtacgt agactcagaa ggccctttga
      301 agcaaggcct gagactctca cagacccctg aggagatggc agccaacctc acagtccaat
      361 cagaatctgg ttgtgccaat gcggtgtctg cagccccatg ccaggcagag ccccagcagt
      421 atgaagtgca gtttggacgc ctgaggagct ttctcaccga ttctgactcc cagtacagcc
      481 gtgaagttat gcctctcctc taccctctct ttgtctacct ccacctcaac ctggtccaga
      541 gtggccctaa gagcaccgtg gaaagcttct atagccgctt ccatgggatg ttcctgcaga
      601 atgcaagtca gaaggacgtc atcgagcagc tgcagaccac acagaccatc caggacattc
      661 tgtcaaactt ccagcttcgt gcattcctgg acaacaagta tgtcgtccgt ctccaggaag
      721 atagctacaa ttaccttatc cgctacctcc aaagcgacaa caacactgcc ctgtgcaaag
      781 tgcttgccgt gcacattcac ttagacgtgc agcctgccaa gaggacagac taccagctgt
      841 acgccagcgg tggctcctcc cgcactgaga acagcagcct ggagccgcca gaggtgccca
      901 gccctattct gcagaatgag gctgccctgg aagtcttgca ggagagtatc aagcgggtca
      961 aggatggacc tccctccctc accaccatct gcttctatgc cttctataac acggaacagc
     1021 tgctgaatac tgcagagatc tcctccgata gcaaactgct ggctgctggg tttgacaact
     1081 cctgcataaa actctggagc ttgcgatcca aaaagctgaa atcagagccc caccatgtgg
     1141 acacatcccg gatccgtcta gcttgtgaca ctctggagga ggaggagaat gaagaagata
     1201 atacaggcac agagatgaag attctgcggg gacactgtgg cccagtatac agcacacggt
     1261 tccttgcaga cagctcaggg ctgctctctt gttctgaaga tatgtccatc agatactggg
     1321 acctggggag cttcaccaac actgtgctgt atcagggaca tgcctaccct gtgtgggacg
     1381 tggacatcag ccccttcagc ctgtactttg ccagtggatc ccatgaccgt accgccaggc
     1441 tgtggtcttt tgatcggacg tacccgctga ggatatatgc aggacacctg gcagatgtgg
     1501 actgtgtcaa attccacccc aactcaaact acttagctac agggtccact gacaaaactg
     1561 ttcggctatg gagtgcccag caggggaact cggtgcggct cttcacaggt caccgaggcc
     1621 ccgtgctctc cctctccttt tctcccaatg gtaagtactt ggcatctgct ggtgaggacc
     1681 agcggttaaa gttgtgggac ttggcctctg ggacactttt taaagaactg agaggccaca
     1741 cggacagcat caccagtctg gcctttagcc cggacagcgg tctgattgct tctgcctcca
     1801 tggacaactc cgtgcgtgtc tgggacatca gaagcacgtg ctgcaacaca cctgctgacg
     1861 gctcttcagg tgagcttgtg ggcgtgtaca ctgggcagat gagcaacgtc ctgagtgtac
     1921 agttcatggc ttgcaacctc ctcctggtga ctggaatcac acaagagaat caagaacatt
     1981 aagtttttat ccaggtggca gactgggtgg ggctggaaga ctggtcacag tccaggactt
     2041 gctaaaaccg aatcagtgat tgcaaaagag ccctccccta tcccacatgc actcaacaca
     2101 gccctggtgc acaagactcc agttgagagc tgggaggctc ccaggctcga ggcctcctgc
     2161 ttcatgcagg caccttgctt ttgcatctgt ctctaccatg ggtgtgctgg gacaggtgca
     2221 gaacctccct gtagcagctg tagacagtct ctcctgtggc tgccccttga gggaagtggg
     2281 aacaggaatt aggaaaggag gggatgacgt ctttcctttt ccatgatgat aaaaccagga
     2341 tttttattat tataattaat aattttatta ttgagaagaa gaaacctagc actggcagca
     2401 agtgactcct ggcactggct ataatacttg gaattttgag gttcagggaa ttcagacttt
     2461 ggtggcccag tgtatcagga gaaaggggca ccatgtgctg tgctctgtgg gcaggcaggt
     2521 agctactgaa catgggctcc tgcagggatg gaggcaaagg aggttcttca ttggctgcac
     2581 ttgtgtcagc acttgtaccc tggggagaag cactgtggtg agcagagggt aggcctcagc
     2641 gttgcaccag ttacccaggg ttccatccct acaccatcaa caaaattatg ataaagaata
     2701 attttgaata agtcacaaga tagacttgag aaatgctgga tttaaagaag actgcttatt
     2761 ccaagctgtg gcttattggt ctttttcccc ctcgatgacc tgcttccacc tctctgcagt
     2821 gtcggtagtg aacaggggat gaatcatgaa tgcgcactcg caagtattga ccatgctctg
     2881 aggacaaagc aagtctgcta aaggattaaa tatttctgtt ttctgaaaag agttattttg
     2941 tattttgttt tctattaaaa tgtatttagt ttcaaaaaaa aaaaaaaaaa
//
