LOCUS       NM_021441               3221 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus TATA-box binding protein associated factor, RNA
            polymerase I, C (Taf1c), transcript variant 1, mRNA.
ACCESSION   NM_021441
VERSION     NM_021441.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3221)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3221)
  AUTHORS   Bardot,P., Vincent,S.D., Fournier,M., Hubaud,A., Joint,M., Tora,L.
            and Pourquie,O.
  TITLE     The TAF10-containing TFIID and SAGA transcriptional complexes are
            dispensable for early somitogenesis in the mouse embryo
  JOURNAL   Development 144 (20), 3808-3818 (2017)
   PUBMED   28893950
REFERENCE   3  (bases 1 to 3221)
  AUTHORS   Okuda,H., Kanai,A., Ito,S., Matsui,H. and Yokoyama,A.
  TITLE     AF4 uses the SL1 components of RNAP1 machinery to initiate MLL
            fusion- and AEP-dependent transcription
  JOURNAL   Nat Commun 6, 8869 (2015)
   PUBMED   26593443
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3221)
  AUTHORS   Murano,K., Okuwaki,M., Momose,F., Kumakura,M., Ueshima,S.,
            Newbold,R.F. and Nagata,K.
  TITLE     Reconstitution of human rRNA gene transcription in mouse cells by a
            complete SL1 complex
  JOURNAL   J Cell Sci 127 (Pt 15), 3309-3319 (2014)
   PUBMED   24928901
REFERENCE   5  (bases 1 to 3221)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   6  (bases 1 to 3221)
  AUTHORS   Heix,J., Zomerdijk,J.C., Ravanpay,A., Tjian,R. and Grummt,I.
  TITLE     Cloning of murine RNA polymerase I-specific TAF factors: conserved
            interactions between the subunits of the species-specific
            transcription initiation factor TIF-IB/SL1
  JOURNAL   Proc Natl Acad Sci U S A 94 (5), 1733-1738 (1997)
   PUBMED   9050847
REFERENCE   7  (bases 1 to 3221)
  AUTHORS   Almendral,J.M., Santaren,J.F., Perera,J., Zerial,M. and Bravo,R.
  TITLE     Expression, cloning and cDNA sequence of a fibroblast
            serum-regulated gene encoding a putative actin-associated protein
            (p27)
  JOURNAL   Exp Cell Res 181 (2), 518-530 (1989)
   PUBMED   2924801
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC104882.30.
            
            On Mar 13, 2020 this sequence version replaced NM_021441.2.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC058383.1, AK030522.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-72                AC104882.30        98321-98392         c
            73-211              AC104882.30        97426-97564         c
            212-296             AC104882.30        96567-96651         c
            297-394             AC104882.30        96336-96433         c
            395-484             AC104882.30        96176-96265         c
            485-558             AC104882.30        96017-96090         c
            559-797             AC104882.30        94728-94966         c
            798-914             AC104882.30        94502-94618         c
            915-1032            AC104882.30        94297-94414         c
            1033-1104           AC104882.30        94137-94208         c
            1105-1240           AC104882.30        93847-93982         c
            1241-1378           AC104882.30        93620-93757         c
            1379-1553           AC104882.30        93002-93176         c
            1554-1691           AC104882.30        92767-92904         c
            1692-3221           AC104882.30        91160-92689         c
FEATURES             Location/Qualifiers
     source          1..3221
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 68.02 cM"
     gene            1..3221
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /note="TATA-box binding protein associated factor, RNA
                     polymerase I, C"
                     /db_xref="GeneID:21341"
                     /db_xref="MGI:MGI:109576"
     exon            1..72
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /inference="alignment:Splign:2.1.0"
     exon            73..211
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..2584
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /note="isoform 1 is encoded by transcript variant 1;
                     transcription factor TAFI95; TATA box binding protein
                     (Tbp)-associated factor, RNA polymerase I, C; TATA
                     box-binding protein-associated factor RNA polymerase I
                     subunit C; TBP-associated factor RNA polymerase I 95 kDa;
                     transcription initiation factor SL1/TIF-IB subunit C; RNA
                     polymerase I-specific TBP-associated factor 95 kDa;
                     TBP-associated factor 1C; TATA box-binding
                     protein-associated factor 1C; TATA box binding protein
                     (Tbp)-associated factor, RNA polymerase I, C;
                     transcription factor TAFI95"
                     /codon_start=1
                     /product="TATA box-binding protein-associated factor RNA
                     polymerase I subunit C isoform 1"
                     /protein_id="NP_067416.2"
                     /db_xref="CCDS:CCDS40493.1"
                     /db_xref="GeneID:21341"
                     /db_xref="MGI:MGI:109576"
                     /translation="MDFPGTLRPSLFKAGPLGMTDGPDLSFMCSWRDALTLPGSQPQN
                     CKDPTLSFAKNLLWEPSTPGPLPLLMPPDPDPWDPGVTAQDFLFRGGHCYQYQSQAVL
                     DVTEQLSRFLWDHGDIAFAPLGRLMLENFRLEGNRGYSKKMTIVSAKKLLQDLGGHQP
                     WGCPWASLSRRLRRFSIVGGPVLSRSVSLLMGKLLHEELAMRWEQLLMDEAFTGGALA
                     WLPGRTARAGQLVYPSGGALDKLYFQEVSVTSGGNPRILENPGHVQLRGPVRQVVTST
                     VQGETLLAVRSDYHCATWKIDKQGPPALLQVMQVEKGATGISLSPHLSGELAICSRSG
                     AVCLWTPQAGLQTIYKDTETLAFRDPSPWRWADFTAHPRVLTVGDRTGVKMVDIQGPP
                     GCGLLLFRAGAEAACQKGERVLLAQYLGQPGQTPPSLHLICTQFSIYLMDERLPLVPM
                     LKWDHGLPSAPLLARLLPPASPGHPRPLLLGGQGGQLQLLHITGEGTSMPQLAGPPQS
                     LPSITESLSAFPLLEPKKQQLLQERLEAPVIGLAAVPLCASAPGLLLFQLSAAGDVFY
                     QHLRLLQASSPRKVPEQATAPSVDQVSTPSWTPQASARCSRWLEDLMELSPTRPLWVA
                     PTFSHRRFLGHMERQKSQETMPQKLRAAMAKGQLLRPGDLSTLPRAEPPPAPQCSQQD
                     ELTERLTEAWEGRVTAWWRRHRGETSETQTQSKRPKRRTQLSSTFSSFTSYLDSPDAS
                     SAPRSQDLSTSEARLQSPRVPPSQELTQEVWGQGVKRERRQTLRDHTDKLPLKRDTPG
                     PVATPPSQASSLQTMSFRQQTPVHSGSQPPQKKPRMGF"
     exon            212..296
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /inference="alignment:Splign:2.1.0"
     exon            297..394
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /inference="alignment:Splign:2.1.0"
     exon            395..484
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /inference="alignment:Splign:2.1.0"
     exon            485..558
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /inference="alignment:Splign:2.1.0"
     exon            559..797
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /inference="alignment:Splign:2.1.0"
     exon            798..914
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1032
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1104
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1240
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1378
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /inference="alignment:Splign:2.1.0"
     exon            1379..1553
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /inference="alignment:Splign:2.1.0"
     exon            1554..1691
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /inference="alignment:Splign:2.1.0"
     exon            1692..3221
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3168..3173
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /note="hexamer: AATAAA"
     polyA_site      3221
                     /gene="Taf1c"
                     /gene_synonym="mTAFI95; Tafi95"
                     /note="major polyA site"
ORIGIN      
        1 agtctgctcc aacagttgtg ggtggcggcg ttgaggttcg gcactctggc tcctttgcgg
       61 ccccggggtc aggatggact tccctggcac cctgcgccct tcattgttta aggccggtcc
      121 acttggcatg actgatggcc ctgacctgtc cttcatgtgc agctggagag atgcactgac
      181 cctgccaggg tcccagccac agaactgcaa ggatccgacc ttgtcctttg ccaagaacct
      241 actgtgggag ccatcgacgc caggacccct ccccctcctg atgcctcctg atcctgatcc
      301 ctgggaccct ggtgtgacag ctcaggactt ccttttccgg ggaggtcact gctaccagta
      361 ccagtctcag gctgtgctgg atgtcactga gcagctcagc cgcttcctgt gggaccatgg
      421 ggacatagcc ttcgcacccc tggggagact catgctggag aacttcagat tggaggggaa
      481 ccggggctac tcgaaaaaga tgactatagt cagcgcgaag aagctgcttc aggacctcgg
      541 cggacaccaa ccctgggggt gtccctgggc ttccctcagc cgccggctgc gtcgcttctc
      601 catcgttggg ggtcctgtcc tgagcaggtc agtgtcacta ctcatgggga agctactgca
      661 tgaagagctg gccatgcgct gggagcagct gctgatggat gaggccttca ccgggggcgc
      721 gttggcctgg ctgcccggaa ggacagcgcg ggccggacag ctggtctacc ctagtggagg
      781 tgccttggac aagctgtatt tccaggaggt cagtgtgact tcaggtggca acccccggat
      841 ccttgagaac cctgggcacg tccagctgcg gggacctgta cggcaggtgg tgaccagcac
      901 cgtccaggga gaaacgcttc tggccgtccg ctctgactat cactgtgcca cgtggaagat
      961 tgataagcag gggccaccag cactcctgca ggtgatgcag gtggagaaag gggccactgg
     1021 tattagcctc agccctcacc tgtcaggaga gctggccatc tgcagccgtt ccggagctgt
     1081 ttgtctgtgg accccacaag ctgggctgca gacgatctac aaggacaccg agacgcttgc
     1141 cttccgtgat ccgtctccct ggcgctgggc agacttcact gcccaccccc gggtgctgac
     1201 tgtgggggac cgcacgggtg tgaaaatggt tgacattcag ggcccaccgg gctgtgggct
     1261 gctgctgttc cgcgctggag cagaggctgc ctgccagaaa ggagagcggg tgctgcttgc
     1321 ccagtaccta gggcagccag gtcagacccc tccatctctg catctcatct gcacccagtt
     1381 ctcgatctac ctgatggatg agcgcctccc cctggtgccc atgcttaagt gggaccatgg
     1441 cttgccatct gctcccctgc ttgcccgcct gctaccccca gctagccctg gccatccacg
     1501 gcccctgcta ctggggggcc agggtgggca gctgcagctg cttcatataa caggagaggg
     1561 aacttccatg ccacagctgg cggggcctcc tcagtctctg ccctccatca ccgaatccct
     1621 ctctgccttt cccctgctgg aacctaagaa gcagcagctg ctgcaggaac gtctggaggc
     1681 accagtcata ggtctggctg ctgtccccct ctgtgcctct gccccggggc tgttgctctt
     1741 ccagctctca gcagccgggg atgtcttcta ccagcaccta cggctcctgc aagcctccag
     1801 tcctagaaag gtgccagagc aagcaacagc accctcagtg gaccaggtgt ccacgccctc
     1861 ttggacccct caggccagtg cccgttgcag ccgctggttg gaggacctga tggagttgtc
     1921 ccccactcgt ccattgtggg tcgccccgac cttctcccat cgccgttttc tgggccacat
     1981 ggagcggcag aagagccaag agaccatgcc acagaagctc cgagcagcca tggccaaggg
     2041 ccagctcctg cggcctgggg acctgagtac actccccagg gcagagccac cccctgcacc
     2101 tcagtgcagc caacaggatg agctcactga gcgcttgaca gaagcctggg aaggccgggt
     2161 gactgcctgg tggaggagac atcgaggtga gacctccgag acccagaccc agtccaagcg
     2221 gcctaagcgg cggactcagt tgtctagcac cttctcctca ttcacaagct acctggactc
     2281 cccagatgcc agcagtgccc ctcgtagcca agacctctct acctcagagg cccgtcttca
     2341 gtcacccagg gttccaccct cccaggagtt gacacaggag gtgtggggcc aaggtgtgaa
     2401 gcgtgaacgc cggcagaccc tccgggatca cacggacaag ctgccactta agagggacac
     2461 tccaggacct gtggctacac caccctccca ggcctctagc ctccagacca tgtctttcag
     2521 gcagcagacg cctgtccact ctggctccca gcctccccag aagaagccac gaatgggctt
     2581 ctgagtgggg aaagccatat ctgagaacct agccttcatc ctggagtgct gcactgagct
     2641 cagccactcc agggcagagc ctcctctgcc tctgccatgc agagagcagt gtgcccatgg
     2701 aaacgtgagc agtgtagaac taggctgaag caatggggaa ccagtccact tcgtgtattt
     2761 gatggtagga tattcccgag agctggctgc agaggctgca tcaggatggc taatgctgag
     2821 tccctgcagt cccaagtccc cccagtctcc tgccttctcc cactgccatt ctctgggcca
     2881 catggagctg cagaaagagc caggagacca tgccacagaa gctccgagca gccacgacca
     2941 agggccagct cctgtagctt ggggatctgg ctacgtctcc agggtagagc caccccctgc
     3001 acctcagtgc agcagggttg ctagaaagta gccttagcct cctgtcctca aagatgcccc
     3061 agctcatgtg ctccccgagg tagcccagtg tgggtcagct gttggaggtt gattgtgcca
     3121 cagtgtacat tggttcagta ggcattgacg ctttgactct gggactgaat aaacctgtcc
     3181 actggccatg agcagatggt tatgtgggca gagcagatgt g
//
