LOCUS       NM_020614               2019 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus TATA-box binding protein associated factor, RNA
            polymerase I, B (Taf1b), transcript variant 1, mRNA.
ACCESSION   NM_020614 XM_973112
VERSION     NM_020614.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2019)
  AUTHORS   Tremblay,M.G., Sibai,D.S., Valere,M., Mars,J.C., Lessard,F.,
            Hori,R.T., Khan,M.M., Stefanovsky,V.Y., LeDoux,M.S. and Moss,T.
  TITLE     Ribosomal DNA promoter recognition is determined in vivo by
            cooperation between UBTF1 and SL1 and is compromised in the
            UBTF-E210K neuroregression syndrome
  JOURNAL   PLoS Genet 18 (2), e1009644 (2022)
   PUBMED   35139074
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2019)
  AUTHORS   Maga,A.M., Navarro,N., Cunningham,M.L. and Cox,T.C.
  TITLE     Quantitative trait loci affecting the 3D skull shape and size in
            mouse and prioritization of candidate genes in-silico
  JOURNAL   Front Physiol 6, 92 (2015)
   PUBMED   25859222
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2019)
  AUTHORS   Murano,K., Okuwaki,M., Momose,F., Kumakura,M., Ueshima,S.,
            Newbold,R.F. and Nagata,K.
  TITLE     Reconstitution of human rRNA gene transcription in mouse cells by a
            complete SL1 complex
  JOURNAL   J Cell Sci 127 (Pt 15), 3309-3319 (2014)
   PUBMED   24928901
REFERENCE   4  (bases 1 to 2019)
  AUTHORS   Adolphe,C., Nieuwenhuis,E., Villani,R., Li,Z.J., Kaur,P., Hui,C.C.
            and Wainwright,B.J.
  TITLE     Patched 1 and patched 2 redundancy has a key role in regulating
            epidermal differentiation
  JOURNAL   J Invest Dermatol 134 (7), 1981-1990 (2014)
   PUBMED   24492243
REFERENCE   5  (bases 1 to 2019)
  AUTHORS   Eckey,M., Kraft,F., Kob,R., Escher,N., Asim,M., Fischer,H.,
            Fritsche,M.K., Melle,C. and Baniahmad,A.
  TITLE     The corepressor activity of Alien is controlled by CREB-binding
            protein/p300
  JOURNAL   FEBS J 280 (8), 1861-1868 (2013)
   PUBMED   23441852
REFERENCE   6  (bases 1 to 2019)
  AUTHORS   Qiu,H., Nomiyama,R., Moriguchi,K., Fukada,T. and Sugimoto,K.
  TITLE     Identification of novel nuclear protein interactions with the
            N-terminal part of filamin A
  JOURNAL   Biosci Biotechnol Biochem 75 (1), 145-147 (2011)
   PUBMED   21228480
REFERENCE   7  (bases 1 to 2019)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   8  (bases 1 to 2019)
  AUTHORS   Sharov,A.A., Piao,Y., Matoba,R., Dudekula,D.B., Qian,Y.,
            VanBuren,V., Falco,G., Martin,P.R., Stagg,C.A., Bassey,U.C.,
            Wang,Y., Carter,M.G., Hamatani,T., Aiba,K., Akutsu,H., Sharova,L.,
            Tanaka,T.S., Kimber,W.L., Yoshikawa,T., Jaradat,S.A., Pantano,S.,
            Nagaraja,R., Boheler,K.R., Taub,D., Hodes,R.J., Longo,D.L.,
            Schlessinger,D., Keller,J., Klotz,E., Kelsoe,G., Umezawa,A.,
            Vescovi,A.L., Rossant,J., Kunath,T., Hogan,B.L., Curci,A.,
            D'Urso,M., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
REFERENCE   9  (bases 1 to 2019)
  AUTHORS   Heix,J., Zomerdijk,J.C., Ravanpay,A., Tjian,R. and Grummt,I.
  TITLE     Cloning of murine RNA polymerase I-specific TAF factors: conserved
            interactions between the subunits of the species-specific
            transcription initiation factor TIF-IB/SL1
  JOURNAL   Proc Natl Acad Sci U S A 94 (5), 1733-1738 (1997)
   PUBMED   9050847
REFERENCE   10 (bases 1 to 2019)
  AUTHORS   Almendral,J.M., Santaren,J.F., Perera,J., Zerial,M. and Bravo,R.
  TITLE     Expression, cloning and cDNA sequence of a fibroblast
            serum-regulated gene encoding a putative actin-associated protein
            (p27)
  JOURNAL   Exp Cell Res 181 (2), 518-530 (1989)
   PUBMED   2924801
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125067.4, AK131963.1 and CK619940.1.
            
            On Aug 28, 2009 this sequence version replaced NM_020614.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the functional protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC057167.1, AK165580.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-27                AC125067.4         41257-41283
            28-910              AK131963.1         2-884
            911-911             AC125067.4         87005-87005
            912-1768            AK131963.1         886-1742
            1769-2019           CK619940.1         372-622
FEATURES             Location/Qualifiers
     source          1..2019
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 8.49 cM"
     gene            1..2019
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /note="TATA-box binding protein associated factor, RNA
                     polymerase I, B"
                     /db_xref="GeneID:21340"
                     /db_xref="MGI:MGI:109577"
     exon            1..69
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..1812
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /note="transcription factor TAFI68; TBP-associated factor
                     RNA polymerase I 68; TBP-associated factor 1B; TATA
                     box-binding protein-associated factor 1B; transcription
                     initiation factor SL1/TIF-IB subunit B; RNA polymerase
                     I-specific TBP-associated factor 68 kDa; TATA box binding
                     protein (Tbp)-associated factor, RNA polymerase I, B"
                     /codon_start=1
                     /product="TATA box-binding protein-associated factor RNA
                     polymerase I subunit B"
                     /protein_id="NP_065639.2"
                     /db_xref="CCDS:CCDS36419.1"
                     /db_xref="GeneID:21340"
                     /db_xref="MGI:MGI:109577"
                     /translation="MDVEEVKAFRDRCSQCAAVSWGLTDEGKYYCTSCHNVTDRSEEV
                     VSAADIPNTKINSINRGLRQRSKHEKGWDWYVCEGFQCILYHQAKALETLGVSPELKN
                     EVLHNFWKRYLQKSKQAYCKNPVRTSGRKAKVLEDSVQSSDLGSDLELLSDTTCPLES
                     EAEFQSDPQIPKPFPVTKGSPKSASVCSGSVDGVEYSERKEKGLVKMTVPRTLALCSL
                     SLLWQRETITVSDLLRFVEEDHIPYINAFKLFPEEMKVYGRDKGIFAIESWPDYEDIY
                     KNMIELAIFLDLPRFPDITEDCYLHPNTLCMKYLLEVNLPDEMHTLTCQVVKLTGIGE
                     VDFLTFDPIAKTKRTVKYDVQAMAVIVVVLKLLFLLDDKLEWSYSDLAEAYNEQHRED
                     TPQFDFRKWYQVMKKTFDEKRRKWEEARARYAWKTKRPLYRSHIDKSVAYKRRKMVEN
                     LQKQFSALVGSSPVVEKQAPSSFQFNWTEEGTDSPCFHGHSLQGLLIMKGQSMITKNS
                     LYWLSTQKFCKSYCKHVTTYEESNFSLSYQFILNIFSFLLRIKTSALHEEVSLLEKKL
                     FEKKYNESKKSSGSKKGRRH"
     exon            70..168
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /inference="alignment:Splign:2.1.0"
     exon            169..256
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /inference="alignment:Splign:2.1.0"
     exon            257..354
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /inference="alignment:Splign:2.1.0"
     exon            355..450
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /inference="alignment:Splign:2.1.0"
     exon            451..601
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /inference="alignment:Splign:2.1.0"
     exon            602..752
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /inference="alignment:Splign:2.1.0"
     exon            753..852
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /inference="alignment:Splign:2.1.0"
     exon            853..1000
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /inference="alignment:Splign:2.1.0"
     exon            1001..1178
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /inference="alignment:Splign:2.1.0"
     exon            1179..1225
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /inference="alignment:Splign:2.1.0"
     exon            1226..1316
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /inference="alignment:Splign:2.1.0"
     exon            1317..1387
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /inference="alignment:Splign:2.1.0"
     exon            1388..1610
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /inference="alignment:Splign:2.1.0"
     exon            1611..2019
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1974..1979
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /note="hexamer: AATACA"
     regulatory      1982..1987
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /note="hexamer: AGTAAA"
     polyA_site      1987
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
                     /note="major polyA site"
     polyA_site      2000
                     /gene="Taf1b"
                     /gene_synonym="4930408G01Rik; A230108M10Rik; p63; TAFI68;
                     Tafi86"
ORIGIN      
        1 cccggaagcg gcgcttgctg tttgggtaac ggtgtctgca gcggagcctc gatggatgtg
       61 gaggaggtga aagcgttcag agaccgctgt tctcagtgtg ctgctgtctc ctggggcctt
      121 accgatgaag gcaaatatta ctgtacttcc tgccacaatg tcacagatcg atctgaggaa
      181 gtggtgagcg ctgcagatat ccccaacacc aagatcaact ccatcaacag ggggctgaga
      241 cagagaagca agcatgagaa aggctgggat tggtatgtgt gtgaaggttt ccagtgcata
      301 ctttatcacc aagcaaaagc cctggagacc ctcggagtaa gcccagaact aaagaatgaa
      361 gtcttacaca atttttggaa gcgctacctt cagaagagca aacaggccta ttgtaaaaac
      421 ccagttcgta caagtggaag gaaagccaag gtattagaag acagtgtgca gtcctcggac
      481 ttgggcagtg atcttgagct gctaagtgat accacatgcc cccttgaaag tgaagcagag
      541 ttccaatctg accctcagat tccaaagcct ttccctgtca ccaaaggatc cccaaagtca
      601 gcgtctgtct gctctggctc tgttgatgga gtggagtact ccgagcggaa ggagaagggg
      661 cttgtgaaga tgacggtgcc caggacactt gctctctgct ctctctcctt gctctggcag
      721 agggaaacaa ttacagtttc agaccttttg aggtttgttg aagaggatca tattccgtac
      781 ataaatgctt ttaagctttt tccagaagag atgaaagtgt atggtcgtga caaaggcatc
      841 tttgctatag agtcttggcc tgactatgaa gacatctata aaaacatgat tgaacttgcc
      901 atatttttag atttgcctcg tttcccagac ataacggaag actgctacct ccatcccaac
      961 accttgtgta tgaaatactt actggaggtc aatctccctg atgaaatgca cactttaacc
     1021 tgtcaagtag taaagttgac tggaattggg gaagtggatt ttctgacgtt tgatcctata
     1081 gctaaaacga aaaggacagt taaatatgat gtgcaggcta tggctgtcat tgtggttgtg
     1141 ttgaagctgc tgtttttgct ggatgacaag ctggaatggt cttactcaga tcttgctgaa
     1201 gcgtacaacg aacaacacag agaagacacg ccccagtttg atttcagaaa atggtaccaa
     1261 gttatgaaga aaacttttga tgagaaaaga cgaaaatggg aagaagcgag ggccaggtat
     1321 gcttggaaaa ccaaaaggcc actctaccgt tcacacatcg ataagtccgt cgcatataag
     1381 agaagaaaaa tggtggagaa tcttcaaaaa caatttagtg ccctggttgg ttcatcaccc
     1441 gtggttgaaa agcaggcccc ttcaagtttt cagttcaact ggactgaaga aggcactgat
     1501 agcccttgtt tccatggaca cagcctccag ggactcctga taatgaaagg ccagtccatg
     1561 ataaccaaga actccctgta ttggctcagt acccagaagt tctgcaaaag ctattgtaaa
     1621 catgtgacaa cttacgaaga atcaaatttt tctttgagtt accagtttat actaaacatc
     1681 ttctccttct tactgagaat aaagacctct gctctccatg aagaagtgag cttacttgaa
     1741 aagaaacttt ttgaaaaaaa atacaacgaa tcaaaaaaga gctcaggatc caagaaagga
     1801 agaagacact gagaaccaga gaggggcttt gacaggcgtt ctcaggacaa ggtgtcaact
     1861 gtgtgaagtc tactgttgaa caggcataca ctttggcatg tgtctttata tgcattgtaa
     1921 gaaatgcttt gaattatttt cataaataat tttttcagaa aattaaaata agtaatacac
     1981 aagtaaatga cacctggaaa cttgcattca ttgtatttt
//
