LOCUS       NM_001277958            2419 bp    mRNA    linear   ROD 23-DEC-2022
DEFINITION  Mus musculus TATA-box binding protein associated factor, RNA
            polymerase I, A (Taf1a), transcript variant 4, mRNA.
ACCESSION   NM_001277958
VERSION     NM_001277958.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2419)
  AUTHORS   Bardot P, Vincent SD, Fournier M, Hubaud A, Joint M, Tora L and
            Pourquie O.
  TITLE     The TAF10-containing TFIID and SAGA transcriptional complexes are
            dispensable for early somitogenesis in the mouse embryo
  JOURNAL   Development 144 (20), 3808-3818 (2017)
   PUBMED   28893950
REFERENCE   2  (bases 1 to 2419)
  AUTHORS   Murano K, Okuwaki M, Momose F, Kumakura M, Ueshima S, Newbold RF
            and Nagata K.
  TITLE     Reconstitution of human rRNA gene transcription in mouse cells by a
            complete SL1 complex
  JOURNAL   J Cell Sci 127 (Pt 15), 3309-3319 (2014)
   PUBMED   24928901
REFERENCE   3  (bases 1 to 2419)
  AUTHORS   Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S,
            Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N,
            Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y,
            Okado H, Hashimoto M and Asahara H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   4  (bases 1 to 2419)
  AUTHORS   Yamamoto K, Yamamoto M, Hanada K, Nogi Y, Matsuyama T and Muramatsu
            M.
  TITLE     Multiple protein-protein interactions by RNA polymerase
            I-associated factor PAF49 and role of PAF49 in rRNA transcription
  JOURNAL   Mol Cell Biol 24 (14), 6338-6349 (2004)
   PUBMED   15226435
REFERENCE   5  (bases 1 to 2419)
  AUTHORS   Heix J, Zomerdijk JC, Ravanpay A, Tjian R and Grummt I.
  TITLE     Cloning of murine RNA polymerase I-specific TAF factors: conserved
            interactions between the subunits of the species-specific
            transcription initiation factor TIF-IB/SL1
  JOURNAL   Proc Natl Acad Sci U S A 94 (5), 1733-1738 (1997)
   PUBMED   9050847
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK133426.1 and BC061106.1.
            
            [WARNING] On May 3, 2023 this sequence was replaced by
            NM_001277958.2.
            
            Transcript Variant: This variant (4) differs in the 5' UTR and uses
            an alternate in-frame splice site, compared to variant 1. The
            encoded isoform (3) is longer than isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133426.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1191              AK133426.1         2-1192
            1192-2419           BC061106.1         1088-2315
FEATURES             Location/Qualifiers
     source          1..2419
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1"
     gene            1..2419
                     /gene="Taf1a"
                     /gene_synonym="mTAFI48; TAFI48"
                     /note="TATA-box binding protein associated factor, RNA
                     polymerase I, A"
                     /db_xref="GeneID:21339"
                     /db_xref="MGI:MGI:109578"
     exon            1..174
                     /gene="Taf1a"
                     /gene_synonym="mTAFI48; TAFI48"
                     /inference="alignment:Splign:2.1.0"
     CDS             175..1557
                     /gene="Taf1a"
                     /gene_synonym="mTAFI48; TAFI48"
                     /note="isoform 3 is encoded by transcript variant 4; TATA
                     box-binding protein-associated factor RNA polymerase I
                     subunit A; TBP-associated factor 1A; TATA box binding
                     protein (Tbp)-associated factor, RNA polymerase I, A; TATA
                     box-binding protein-associated factor 1A; transcription
                     initiation factor SL1/TIF-IB subunit A; RNA polymerase
                     I-specific TBP-associated factor 48 kDa"
                     /codon_start=1
                     /product="TATA box-binding protein-associated factor RNA
                     polymerase I subunit A isoform 3"
                     /protein_id="NP_001264887.1"
                     /db_xref="GeneID:21339"
                     /db_xref="MGI:MGI:109578"
                     /translation="MMSDFGEELTKLAVAEDNPETSVLSKTGMHFPWLHKHVEAVVTG
                     GKKRKDFAQTTSACLSFIQEALLKHQWQQAAEYMHSYLQTLEDSDTDKRQAAPEIIWK
                     LGSEILFYHPKSNVETFNSFADRMKNIGVLNYLKWVFLLVQISLQHALYLLHHGMLDD
                     ANRNLSKAETWRYGEKSSSQEVLINLVQAYKGLLQYYTWTRKKMELSKLDEDDYAYAA
                     KTRTMLSQSCKTSTNICALVKTPGVWDPFVKSYVEMLEFYGDQDGAREMLTNYAYDEK
                     FPSNPNAHVYLYEFLKREKAPRAKLISVLKILHEIVPSHTLMLEFHTLLRKSDTEEHQ
                     KLGLSVLFEVLDFAGCNKNITAWKYLAKYLKQILVGSHHEWVEEEWKSRRNWWPAFHF
                     SFFWAKSDWKADTDLACEKAFVAGVLLGKGCKYFRYILKQDHETLKKKIKRMKKSVKK
                     YTIVNPGVHT"
     exon            175..298
                     /gene="Taf1a"
                     /gene_synonym="mTAFI48; TAFI48"
                     /inference="alignment:Splign:2.1.0"
     exon            299..468
                     /gene="Taf1a"
                     /gene_synonym="mTAFI48; TAFI48"
                     /inference="alignment:Splign:2.1.0"
     exon            469..582
                     /gene="Taf1a"
                     /gene_synonym="mTAFI48; TAFI48"
                     /inference="alignment:Splign:2.1.0"
     exon            583..802
                     /gene="Taf1a"
                     /gene_synonym="mTAFI48; TAFI48"
                     /inference="alignment:Splign:2.1.0"
     exon            803..933
                     /gene="Taf1a"
                     /gene_synonym="mTAFI48; TAFI48"
                     /inference="alignment:Splign:2.1.0"
     exon            934..1092
                     /gene="Taf1a"
                     /gene_synonym="mTAFI48; TAFI48"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1159
                     /gene="Taf1a"
                     /gene_synonym="mTAFI48; TAFI48"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..1283
                     /gene="Taf1a"
                     /gene_synonym="mTAFI48; TAFI48"
                     /inference="alignment:Splign:2.1.0"
     exon            1284..1438
                     /gene="Taf1a"
                     /gene_synonym="mTAFI48; TAFI48"
                     /inference="alignment:Splign:2.1.0"
     exon            1439..2405
                     /gene="Taf1a"
                     /gene_synonym="mTAFI48; TAFI48"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agggttttcc ggggcggcga acaacgtgga gtcgggcgac tctggagctt ggatttagcg
       61 gctcgcgggc tccgtacgcc ttgcgctttc agtgaaacag gaaaaggtgt gtgagcctcc
      121 tgcttgttcc ttctgcggtt tcctcttgac tttgtgctcc tgggctctga gaccatgatg
      181 agtgatttcg gtgaagagtt gacaaagctg gctgtggcag aggataaccc agaaacgtcg
      241 gtgctctcta aaacgggaat gcatttccca tggcttcaca agcacgttga agctgtagtg
      301 actggaggga agaagaggaa ggattttgct cagacgacaa gtgcttgttt aagctttatc
      361 caggaagccc tgctgaagca ccagtggcag caagctgcag agtatatgca cagttacctg
      421 cagaccctgg aggactcaga caccgacaag agacaggctg cccctgagat catttggaag
      481 cttggaagtg aaattctatt ttaccacccc aaaagcaatg tggagacttt taatagcttc
      541 gctgaccgga tgaaaaatat tggtgtcttg aattatttaa agtgggtttt cttattggtg
      601 cagatctcct tacaacacgc cttgtatctt ttacatcatg gaatgcttga tgatgcgaac
      661 aggaacctga gtaaggcaga gacgtggagg tatggagaaa agtcgtcttc tcaggaagtg
      721 ttgatcaacc ttgttcaggc ttacaaaggg cttctgcagt actacacttg gaccagaaag
      781 aagatggagt tgtcaaagct tgatgaagat gattacgctt acgccgccaa aacccgaacc
      841 atgctcagcc agagctgcaa gacgtctaca aatatctgtg cactggtcaa aacccccggg
      901 gtctgggatc cttttgtgaa gagttatgtg gagatgctgg agttctatgg tgatcaagat
      961 ggagcccgag agatgctcac caattatgca tatgatgaga agttcccgtc gaaccccaac
     1021 gcccacgtct acttatacga gtttctcaag agagagaagg caccgagggc gaagctcata
     1081 agtgttctta agattttaca tgagattgtg ccatcccata cactaatgtt agaattccat
     1141 acattgctta gaaaatcaga cacagaagaa caccagaaac tgggcttgtc tgtgttattt
     1201 gaagtcctgg acttcgctgg atgcaataag aacataacgg cctggaaata cttggcaaag
     1261 tatctgaagc agatattagt gggaagccat cacgagtggg ttgaagaaga gtggaagtct
     1321 aggaggaact ggtggccagc ttttcacttc agcttctttt gggcgaagag tgactggaag
     1381 gcagacactg acttggcttg tgagaaagct tttgtggcag gggtcctttt aggaaaaggt
     1441 tgtaaatatt ttcggtatat tttaaaacaa gatcatgaaa ccttgaagaa gaaaatcaag
     1501 cgaatgaaga agtctgtgaa aaaatacact attgtaaatc caggtgttca cacctagatt
     1561 ttaacttatt ttacagttat cgctacagtg tagtggttca tttacacata cacgcacttg
     1621 tgcacatgcg catgtggaag ctagaagtca gctgtgtcac tcgctgcagg agcctggctt
     1681 tgagaccctc actgagacct ggaggaggcg ctcggcctcc ctcccacctg tttgttcctc
     1741 caccagcttc atttccacac cccacagcta ctaatgggtg ctgttgagtg gggggtagag
     1801 agtcgaggag gaggaggagg tgacaccatg tgactctcca gtcctttgac tctagaggac
     1861 tgatttgagt cagagtgcta gaagagatgt ggttgacctt aaaggcgtgg tgtgctagga
     1921 tacttggatg ttccctcaga aatgagaatc cagctgggcg gtggtggcgc acgtctttaa
     1981 tcccaggagg cagaggcagg cagatttctg agtttgaggc cagcctggtc tacagagtga
     2041 gttccagaac agccagggct acacagagaa agcccgtctc aaaaagaaac aaagcaaaac
     2101 aacaaaaaaa ggaggctcca acagtagcat ctctatccat gaagtagcgt cctgcaggca
     2161 ctgagtaagt aagcacagcg ggacagcttc ccaaggccag agacaccctg ggctctgtag
     2221 ctcatgtgct gatgggtgct tctagagaat gaccttggct gccttgtagt tattgttaaa
     2281 gtacttggat tccaggaagg ctcactgggg ctcaggagac aaaccacaca tttcctcatt
     2341 ggcttatagc cctactagct ttaaataatg aacaataaaa gtggaaaagt tgtgctttgt
     2401 gataaaaaaa aaaaaaaaa
//
