LOCUS       NM_020024                762 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus TATA-box binding protein associated factor 10 (Taf10),
            transcript variant 1, mRNA.
ACCESSION   NM_020024
VERSION     NM_020024.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 762)
  AUTHORS   El-Saafin,F., Bergamasco,M.I., Chen,Y., May,R.E., Esakky,P.,
            Hediyeh-Zadeh,S., Dixon,M., Wilcox,S., Davis,M.J., Strasser,A.,
            Smyth,G.K., Thomas,T. and Voss,A.K.
  TITLE     Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic
            neuronal cell death
  JOURNAL   Cell Death Differ 29 (5), 1013-1027 (2022)
   PUBMED   35361962
REFERENCE   2  (bases 1 to 762)
  AUTHORS   Robbe,Z.L., Shi,W., Wasson,L.K., Scialdone,A.P., Wilczewski,C.M.,
            Sheng,X., Hepperla,A.J., Akerberg,B.N., Pu,W.T., Cristea,I.M.,
            Davis,I.J. and Conlon,F.L.
  TITLE     CHD4 is recruited by GATA4 and NKX2-5 to repress noncardiac gene
            programs in the developing heart
  JOURNAL   Genes Dev 36 (7-8), 468-482 (2022)
   PUBMED   35450884
REFERENCE   3  (bases 1 to 762)
  AUTHORS   Bardot,P., Vincent,S.D., Fournier,M., Hubaud,A., Joint,M., Tora,L.
            and Pourquie,O.
  TITLE     The TAF10-containing TFIID and SAGA transcriptional complexes are
            dispensable for early somitogenesis in the mouse embryo
  JOURNAL   Development 144 (20), 3808-3818 (2017)
   PUBMED   28893950
  REMARK    GeneRIF: the TAF10-containing canonical TFIID and SAGA complexes
            are dispensable for early paraxial mesoderm development, arguing
            against the generic role in transcription proposed for these fully
            assembled holo-complexes
REFERENCE   4  (bases 1 to 762)
  AUTHORS   Langer,D., Martianov,I., Alpern,D., Rhinn,M., Keime,C., Dolle,P.,
            Mengus,G. and Davidson,I.
  TITLE     Essential role of the TFIID subunit TAF4 in murine embryogenesis
            and embryonic stem cell differentiation
  JOURNAL   Nat Commun 7, 11063 (2016)
   PUBMED   27026076
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 762)
  AUTHORS   Papadopoulos,P., Gutierrez,L., Demmers,J., Scheer,E.,
            Pourfarzad,F., Papageorgiou,D.N., Karkoulia,E., Strouboulis,J., van
            de Werken,H.J., van der Linden,R., Vandenberghe,P., Dekkers,D.H.,
            Philipsen,S., Grosveld,F. and Tora,L.
  TITLE     TAF10 Interacts with the GATA1 Transcription Factor and Controls
            Mouse Erythropoiesis
  JOURNAL   Mol Cell Biol 35 (12), 2103-2118 (2015)
   PUBMED   25870109
  REMARK    GeneRIF: By ablating TAF10 specifically in erythroid cells in vivo,
            observed is a differentiation block accompanied by deregulated
            GATA1 target genes, including Gata1 itself, suggesting functional
            cross talk between GATA1 and TAF10.
REFERENCE   6  (bases 1 to 762)
  AUTHORS   Metzger,D., Scheer,E., Soldatov,A. and Tora,L.
  TITLE     Mammalian TAF(II)30 is required for cell cycle progression and
            specific cellular differentiation programmes
  JOURNAL   EMBO J 18 (17), 4823-4834 (1999)
   PUBMED   10469660
REFERENCE   7  (bases 1 to 762)
  AUTHORS   Brand,M., Yamamoto,K., Staub,A. and Tora,L.
  TITLE     Identification of TATA-binding protein-free TAFII-containing
            complex subunits suggests a role in nucleosome acetylation and
            signal transduction
  JOURNAL   J Biol Chem 274 (26), 18285-18289 (1999)
   PUBMED   10373431
REFERENCE   8  (bases 1 to 762)
  AUTHORS   Schiltz,R.L., Mizzen,C.A., Vassilev,A., Cook,R.G., Allis,C.D. and
            Nakatani,Y.
  TITLE     Overlapping but distinct patterns of histone acetylation by the
            human coactivators p300 and PCAF within nucleosomal substrates
  JOURNAL   J Biol Chem 274 (3), 1189-1192 (1999)
   PUBMED   9880483
REFERENCE   9  (bases 1 to 762)
  AUTHORS   Ogryzko,V.V., Kotani,T., Zhang,X., Schiltz,R.L., Howard,T.,
            Yang,X.J., Howard,B.H., Qin,J. and Nakatani,Y.
  TITLE     Histone-like TAFs within the PCAF histone acetylase complex
  JOURNAL   Cell 94 (1), 35-44 (1998)
   PUBMED   9674425
REFERENCE   10 (bases 1 to 762)
  AUTHORS   Le Douarin,B., Zechel,C., Garnier,J.M., Lutz,Y., Tora,L.,
            Pierrat,P., Heery,D., Gronemeyer,H., Chambon,P. and Losson,R.
  TITLE     The N-terminal part of TIF1, a putative mediator of the
            ligand-dependent activation function (AF-2) of nuclear receptors,
            is fused to B-raf in the oncogenic protein T18
  JOURNAL   EMBO J 14 (9), 2020-2033 (1995)
   PUBMED   7744009
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC121823.3.
            
            On Mar 18, 2023 this sequence version replaced NM_020024.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC080311.1, BQ947405.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-257               AC121823.3         122225-122481
            258-412             AC121823.3         122584-122738
            413-477             AC121823.3         123076-123140
            478-592             AC121823.3         123228-123342
            593-762             AC121823.3         123505-123674
FEATURES             Location/Qualifiers
     source          1..762
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 55.97 cM"
     gene            1..762
                     /gene="Taf10"
                     /gene_synonym="30kDa; Taf2h; TAFII30"
                     /note="TATA-box binding protein associated factor 10"
                     /db_xref="GeneID:24075"
                     /db_xref="MGI:MGI:1346320"
     exon            1..257
                     /gene="Taf10"
                     /gene_synonym="30kDa; Taf2h; TAFII30"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..682
                     /gene="Taf10"
                     /gene_synonym="30kDa; Taf2h; TAFII30"
                     /note="isoform 1 is encoded by transcript variant 1; TAF10
                     RNA polymerase II, TATA box binding protein
                     (TBP)-associated factor, 30 kDa; TATA box binding protein
                     (TBP)-associated factor, RNA polymerase II, H, 30 kDa;
                     transcription initiation factor TFIID subunit 10;
                     TAFII-30; mTAFII30; TAF(II)30; transcription initiation
                     factor TFIID 30 kDa subunit"
                     /codon_start=1
                     /product="transcription initiation factor TFIID subunit 10
                     isoform 1"
                     /protein_id="NP_064408.2"
                     /db_xref="CCDS:CCDS21660.1"
                     /db_xref="GeneID:24075"
                     /db_xref="MGI:MGI:1346320"
                     /translation="MSCSGSGADPEAATACAASVAGPAPLVSAPAALPTSTAAESKAS
                     PAGTAGGPVAGVATAGTGPVAARAGEPAERRGPASVAAGGAAPPEGAMSNGVYALPSA
                     ANGEVKPVVSSTPLVDFLMQLEDYTPTIPDAVTGYYLNRAGFEASDPRIIRLISLAAQ
                     KFISDIANDALQHCKMKGTASGSSRSKSKDRKYTLTMEDLTPALSEYGINVKKPHYFT
                     "
     exon            258..412
                     /gene="Taf10"
                     /gene_synonym="30kDa; Taf2h; TAFII30"
                     /inference="alignment:Splign:2.1.0"
     exon            413..477
                     /gene="Taf10"
                     /gene_synonym="30kDa; Taf2h; TAFII30"
                     /inference="alignment:Splign:2.1.0"
     exon            478..592
                     /gene="Taf10"
                     /gene_synonym="30kDa; Taf2h; TAFII30"
                     /inference="alignment:Splign:2.1.0"
     exon            593..762
                     /gene="Taf10"
                     /gene_synonym="30kDa; Taf2h; TAFII30"
                     /inference="alignment:Splign:2.1.0"
     regulatory      741..746
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Taf10"
                     /gene_synonym="30kDa; Taf2h; TAFII30"
                     /note="hexamer: AATAAA"
     polyA_site      762
                     /gene="Taf10"
                     /gene_synonym="30kDa; Taf2h; TAFII30"
                     /note="major polyA site"
ORIGIN      
        1 gttcgccgcc tttcccaccg gccccatgag ctgcagcggc tccggcgcgg accccgaggc
       61 ggcgaccgcc tgtgccgcct cggtcgcggg tccggcaccc ctggtgtcgg ctcccgctgc
      121 gctgcccact agcacggccg cggagagcaa ggccagcccc gcggggacag cagggggccc
      181 cgtggctgga gtcgccactg cgggcacggg ccccgtggcg gcacgggcag gggagccggc
      241 agagcggcgc gggccagctt cggtggcagc gggcggcgcg gctcccccgg agggggcaat
      301 gtctaacggg gtttacgccc taccgagcgc ggccaacgga gaagtgaagc ccgtagtgtc
      361 cagcacacct ctagtggact tcttgatgca gttggaggat tacacaccta cgatcccaga
      421 tgcagtgact ggttactacc tgaaccgcgc tggctttgaa gcttcagacc cacgcataat
      481 tcggctcatc tcactagctg cccagaaatt catctcagat attgccaatg atgccctaca
      541 gcactgcaaa atgaagggca cagcctctgg cagctcccgg agcaagagca aggatcgcaa
      601 gtacacccta accatggagg acttgacccc tgccctcagc gagtatggca tcaatgtgaa
      661 gaagccgcac tacttcacct gagccacgca acccagatgt atttgtcttt ccctctgtcc
      721 ccacacgagc ctgttttcat aataaacttt attgtgacag gc
//
