LOCUS       NM_001170454            3791 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus transcriptional adaptor 2B (Tada2b), mRNA.
ACCESSION   NM_001170454
VERSION     NM_001170454.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3791)
  AUTHORS   Nagy Z, Riss A, Romier C, le Guezennec X, Dongre AR, Orpinell M,
            Han J, Stunnenberg H and Tora L.
  TITLE     The human SPT20-containing SAGA complex plays a direct role in the
            regulation of endoplasmic reticulum stress-induced genes
  JOURNAL   Mol Cell Biol 29 (6), 1649-1660 (2009)
   PUBMED   19114550
REFERENCE   2  (bases 1 to 3791)
  AUTHORS   Guelman S, Kozuka K, Mao Y, Pham V, Solloway MJ, Wang J, Wu J, Lill
            JR and Zha J.
  TITLE     The double-histone-acetyltransferase complex ATAC is essential for
            mammalian development
  JOURNAL   Mol Cell Biol 29 (5), 1176-1188 (2009)
   PUBMED   19103755
REFERENCE   3  (bases 1 to 3791)
  AUTHORS   Zhao Y, Lang G, Ito S, Bonnet J, Metzger E, Sawatsubashi S, Suzuki
            E, Le Guezennec X, Stunnenberg HG, Krasnov A, Georgieva SG, Schule
            R, Takeyama K, Kato S, Tora L and Devys D.
  TITLE     A TFTC/STAGA module mediates histone H2A and H2B deubiquitination,
            coactivates nuclear receptors, and counteracts heterochromatin
            silencing
  JOURNAL   Mol Cell 29 (1), 92-101 (2008)
   PUBMED   18206972
REFERENCE   4  (bases 1 to 3791)
  AUTHORS   Martinez E, Palhan VB, Tjernberg A, Lymar ES, Gamper AM, Kundu TK,
            Chait BT and Roeder RG.
  TITLE     Human STAGA complex is a chromatin-acetylating transcription
            coactivator that interacts with pre-mRNA splicing and DNA
            damage-binding factors in vivo
  JOURNAL   Mol Cell Biol 21 (20), 6782-6795 (2001)
   PUBMED   11564863
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB653255.1 and AC131803.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11927934.4028602.1,
                                           SRR11927933.465658.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-587               BB653255.1         1-587
            588-3791            AC131803.3         133154-136357       c
FEATURES             Location/Qualifiers
     source          1..3791
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 19.14 cM"
     gene            1..3791
                     /gene="Tada2b"
                     /gene_synonym="Gm145"
                     /note="transcriptional adaptor 2B"
                     /db_xref="GeneID:231151"
                     /db_xref="MGI:MGI:3035274"
     exon            1..498
                     /gene="Tada2b"
                     /gene_synonym="Gm145"
                     /inference="alignment:Splign:2.1.0"
     CDS             229..1491
                     /gene="Tada2b"
                     /gene_synonym="Gm145"
                     /codon_start=1
                     /product="transcriptional adapter 2-beta"
                     /protein_id="NP_001163925.1"
                     /db_xref="CCDS:CCDS51478.1"
                     /db_xref="GeneID:231151"
                     /db_xref="MGI:MGI:3035274"
                     /translation="MAELGKKYCVYCLAEVSPLRFRCTECQDIELCPECFSAGAEIGH
                     HRRYHGYQLVDGGRFTLWGPEAEGGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRT
                     PQEVMEHYVSMYIHGNLGKACIPDTIPNRVTDHTCPSGGPLSPSLTTPLPPLDISVAE
                     QQQLGYMPLRDDYEIEYDQDAETLISGLSVNYDDDDVEIELKRAHVDMYVRKLKERQR
                     RKNIARDYNLVPAFLGKDKKEKEKTLKRKITKEEKELRLKLRPLYQFMSCKEFDDLFE
                     NMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKRERRKENKNLASSKRGKEDG
                     KDSEFAAIENLPGFELLSDREKVLCSSLNLSPARYVTVKTIIIKDHLQKRQGIPSKSR
                     LPSYLDKVLKKRILNFLTESGWISRDAS"
     exon            499..3791
                     /gene="Tada2b"
                     /gene_synonym="Gm145"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagacagcg gctgcggcgg cggcggccgg gccgggccgg agggcgcctg cgtgctgagg
       61 cgggacgcgg cccgcctggc cggctccggc ggcgcctggg cgggggcggc cgtggcagcg
      121 gccggcagcg gcacgggcgc ggcgggcgca gcgagcccgg caggcggcgg ggcgctgacg
      181 gccgggggcg cggcggctgc gggccgggcg gcgggcgagc gggggaagat ggcggagctg
      241 ggtaagaagt actgcgtgta ctgcttggcc gaggtgagcc cgctgcgctt ccgctgcaca
      301 gagtgccagg acatcgagct gtgccccgag tgcttctcgg ccggcgcgga gatcggccac
      361 caccgccgct accacggcta ccagctggta gacggcggac gattcacact ctggggtcct
      421 gaggcggagg gcggctggac cagccgcgag gagcagctgc tgctggacgc catcgagcag
      481 ttcggcttcg gcaactggga agacatggct gcacatgttg gtgcttcacg gactccccag
      541 gaagtgatgg agcactacgt tagcatgtat atccatggga acttgggcaa agcctgcatc
      601 cctgacacca tccccaaccg ggtgacagat cacacctgcc ccagtggagg ccctctctcg
      661 cctagcctta ccacaccttt acccccattg gacatctctg tggctgagca gcagcagctg
      721 ggctacatgc cactgcgaga tgattatgag atagagtatg accaggatgc cgagacgctc
      781 atcagtgggc tgtctgtgaa ctatgacgat gatgatgtgg agatagagct caagcgtgcc
      841 catgtagaca tgtatgtgcg gaagctgaag gagaggcagc gccggaagaa cattgccaga
      901 gactataacc tggtgccagc cttcctgggc aaggacaaga aggagaagga gaagacattg
      961 aagagaaaga tcaccaagga ggagaaagag ctgcggctca aactacggcc actctaccag
     1021 ttcatgtcct gcaaagaatt tgatgattta tttgaaaata tgcacaaaga aaagatgctt
     1081 cgcgccaaga ttcgagagct gcagcgctac cggcgcaatg gcattacaaa gatggaggag
     1141 tcggccgaat atgaggccgc cagacacaaa cgggagagga ggaaggagaa caaaaacctg
     1201 gccagctcca aaagggggaa ggaggatggc aaagacagcg agtttgcagc cattgagaac
     1261 cttcctgggt ttgagctgct gtcagatagg gagaaggttc tctgtagttc attgaacttg
     1321 agtcctgcac gctatgtgac tgtgaagact attataatta aagatcacct ccagaagcgg
     1381 caagggatcc cctctaaaag ccgccttccc agttatctgg acaaggtcct aaagaaaagg
     1441 attttaaatt tcctcacaga aagtgggtgg atatccaggg atgcttcctg aggccagatg
     1501 atgctaaagc agcttgtgag ccaaatgatc tggggtctcc cccaacattg ttgctctttt
     1561 aaacaaattg aattcttttt tcaaggctta aatttttttt tttcatgacc ttctggaaga
     1621 agcaatagta gcaatcttaa atttgactca taggggagat aagcgtgtgt ctttttaact
     1681 tagtcctaag gtaatccatt cagaagacag cttgcctttg tgttcctatg aagactgtcc
     1741 ccaaccttgg acgtgtcccc tttatttcat gagcctttcc ccgtttgggt taagaagctg
     1801 ttatgctgtg ggagccagga gccgtgtgtt cctgccatca gcttttctct ggtgacacaa
     1861 gctttactca ggagggctgt tgttggcacc cctttgctga gcccactgct gccccccctc
     1921 cccagctgac accccaagca cagccccggc acaccgcact ttaccgggag gcaggctgtg
     1981 cacagaaccc tctgctgtgg aggccagaga ccaccaccag gcccgctccc cactgagcca
     2041 cttaagatga gcccctcatt tgcacacagt gaccacatga gcttccactt acctaacaac
     2101 agccatttca ggccctcaat agtgcttgct tcatcttagc ctggcccagc ctgggctgcc
     2161 tggacaggct ctcctggcac attcctgtac cctttaaatg ggaaagcagt taacggaagg
     2221 gccacagggt cagatgaggg ctgcctttcg ctgctgtgaa cacttacagt acacctgact
     2281 tggaagaccc ttttgagttc aaggcagagt gtgcaatgtt gaaatggagc agtaggtgct
     2341 gaggacttcc actaccattg tagatcccct ttcactaaat ataagacatg ctagctagcc
     2401 tggctcagtg agctgattag cgtatggcag ggggcctagg aagtacagag catcctgcct
     2461 gtgccttgga gcctgtgcac tgcttttgta tgtgatcttg caacaaactc agaaatggct
     2521 ccttcccagc cctactgaaa agcttgtttc tggggcctcc ttcacggatt catatggtac
     2581 cttccttcta aacttgagga aggcatttgt cttccggctg ctcagggctc tcacgcccag
     2641 accctgcttt agagtcctgg agtgaccaca gcccctgccc cctgtccctg agaggtacaa
     2701 gagcctgttt acctcataga gtgtttgggc tcggaagtaa aagtgaagtt attttgaaga
     2761 aaacaactca tttccaagga cgacatgacg acgtgccttt tcattttaca tcctctgtcc
     2821 cctagggtaa gtttttcagc attaaataaa acatttcaaa tatactgtaa atggctttag
     2881 ttgtaaagtg cattgtgggc cagcaggccc agatttctct tgacaccaga agatgctgag
     2941 caatggtgtc aaaggaccag ctccacactg ccccctgcag ttgaatagtg gacagtagct
     3001 ggtgtgactg aacagcaatg gggtggttgg tactcaatgc ctaggtgagc cagtggttct
     3061 caaagtaggg ttccccaggc actgtcagaa atacagtcat accccaggtt aaatctcgaa
     3121 gcagagattt gggggcttca ttaacaggga ctagcagggt gtttttcaaa ccatcccggt
     3181 ggctgggatg caagctcaag tttgagaacc actggttttg tcctggtgtt tccagcacca
     3241 gaatcccagc ttggtgaggt ttgaagtttc agtgtgtctt ctacaaaatg acagccacat
     3301 ctacattagc ttgagaagca gaggattctg tcaacatgtg gccaagggct gttggacaaa
     3361 aagctgtgct taagcaggca tatagtgtgt gtacatcttt cgatgatata aatttatttg
     3421 ggcgtgactg ttttaaaaca ccataatgaa tgtataatta atttatgttc aagtattaat
     3481 attgttacaa gggaaaagta atattaggat tgtttgctct cctgtctgcc ccagctgttt
     3541 ctggcatatt attttttgtt agctgagaca ttgacatgtt tgtatttaat tctcttgata
     3601 aattagctac tacaacccca tggaaccaag tcttttcaaa tttcaacaaa ttgtctttga
     3661 gtcagaaaag ttagataatt cttcaactgt ttgaaataat gctctctggg aggccaacat
     3721 tccaagaatg tatgaagaac tgaaacccta ccatttttat tcttctttta cattaaattg
     3781 ttgagaacag a
//
