LOCUS       NM_030245               2159 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus transcriptional adaptor 1 (Tada1), mRNA.
ACCESSION   NM_030245
VERSION     NM_030245.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2159)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2159)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 2159)
  AUTHORS   Lumayag,S., Haldin,C.E., Corbett,N.J., Wahlin,K.J., Cowan,C.,
            Turturro,S., Larsen,P.E., Kovacs,B., Witmer,P.D., Valle,D.,
            Zack,D.J., Nicholson,D.A. and Xu,S.
  TITLE     Inactivation of the microRNA-183/96/182 cluster results in
            syndromic retinal degeneration
  JOURNAL   Proc Natl Acad Sci U S A 110 (6), E507-E516 (2013)
   PUBMED   23341629
REFERENCE   4  (bases 1 to 2159)
  AUTHORS   Nagy,Z., Riss,A., Romier,C., le Guezennec,X., Dongre,A.R.,
            Orpinell,M., Han,J., Stunnenberg,H. and Tora,L.
  TITLE     The human SPT20-containing SAGA complex plays a direct role in the
            regulation of endoplasmic reticulum stress-induced genes
  JOURNAL   Mol Cell Biol 29 (6), 1649-1660 (2009)
   PUBMED   19114550
REFERENCE   5  (bases 1 to 2159)
  AUTHORS   Zhao,Y., Lang,G., Ito,S., Bonnet,J., Metzger,E., Sawatsubashi,S.,
            Suzuki,E., Le Guezennec,X., Stunnenberg,H.G., Krasnov,A.,
            Georgieva,S.G., Schule,R., Takeyama,K., Kato,S., Tora,L. and
            Devys,D.
  TITLE     A TFTC/STAGA module mediates histone H2A and H2B deubiquitination,
            coactivates nuclear receptors, and counteracts heterochromatin
            silencing
  JOURNAL   Mol Cell 29 (1), 92-101 (2008)
   PUBMED   18206972
REFERENCE   6  (bases 1 to 2159)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   7  (bases 1 to 2159)
  AUTHORS   Martinez,E., Palhan,V.B., Tjernberg,A., Lymar,E.S., Gamper,A.M.,
            Kundu,T.K., Chait,B.T. and Roeder,R.G.
  TITLE     Human STAGA complex is a chromatin-acetylating transcription
            coactivator that interacts with pre-mRNA splicing and DNA
            damage-binding factors in vivo
  JOURNAL   Mol Cell Biol 21 (20), 6782-6795 (2001)
   PUBMED   11564863
REFERENCE   8  (bases 1 to 2159)
  AUTHORS   Bergstrom,D.E., Gagnon,L.H. and Eicher,E.M.
  TITLE     Genetic and physical mapping of the dreher locus on mouse
            chromosome 1
  JOURNAL   Genomics 59 (3), 291-299 (1999)
   PUBMED   10444330
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY057637.1, AK151132.1, AC161807.12 and DV645054.1.
            
            On May 1, 2009 this sequence version replaced NM_030245.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC027337.1, AK151132.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-139               BY057637.1         2-140
            140-1313            AK151132.1         2-1175
            1314-1314           AC161807.12        91021-91021         c
            1315-2140           AK151132.1         1177-2002
            2141-2159           DV645054.1         197-215
FEATURES             Location/Qualifiers
     source          1..2159
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 73.74 cM"
     gene            1..2159
                     /gene="Tada1"
                     /gene_synonym="2900026B15Rik; D1Ertd251e; Staf42; Tada1l"
                     /note="transcriptional adaptor 1"
                     /db_xref="GeneID:27878"
                     /db_xref="MGI:MGI:1196415"
     exon            1..310
                     /gene="Tada1"
                     /gene_synonym="2900026B15Rik; D1Ertd251e; Staf42; Tada1l"
                     /inference="alignment:Splign:2.1.0"
     CDS             237..1244
                     /gene="Tada1"
                     /gene_synonym="2900026B15Rik; D1Ertd251e; Staf42; Tada1l"
                     /note="transcriptional adaptor 1 (HFI1 homolog, yeast)
                     like; transcriptional adapter 1-like protein"
                     /codon_start=1
                     /product="transcriptional adapter 1"
                     /protein_id="NP_084521.1"
                     /db_xref="CCDS:CCDS15450.1"
                     /db_xref="GeneID:27878"
                     /db_xref="MGI:MGI:1196415"
                     /translation="MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFD
                     LEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSAAKPGKPKGKKKL
                     SSVRQKFDHRFQPQNPLSGAQQFVAKEPQGDDDLKLCSHTMMLPTRGQLEGRMIVTAY
                     EHGLDNVTEEAVSAVVYAVENHLKDILTSVVSRRKAYRVRDGHFKYAFGSNVTPQPYL
                     KNSVVAYNNLVEGPPAFSAPCANQSPASQPHPDDAEQQAAFLLACSGDTLPASLPPVN
                     MYDLFEALQVHREVIPTHTVYALNIERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLL
                     C"
     exon            311..402
                     /gene="Tada1"
                     /gene_synonym="2900026B15Rik; D1Ertd251e; Staf42; Tada1l"
                     /inference="alignment:Splign:2.1.0"
     exon            403..468
                     /gene="Tada1"
                     /gene_synonym="2900026B15Rik; D1Ertd251e; Staf42; Tada1l"
                     /inference="alignment:Splign:2.1.0"
     exon            469..566
                     /gene="Tada1"
                     /gene_synonym="2900026B15Rik; D1Ertd251e; Staf42; Tada1l"
                     /inference="alignment:Splign:2.1.0"
     exon            567..776
                     /gene="Tada1"
                     /gene_synonym="2900026B15Rik; D1Ertd251e; Staf42; Tada1l"
                     /inference="alignment:Splign:2.1.0"
     exon            777..928
                     /gene="Tada1"
                     /gene_synonym="2900026B15Rik; D1Ertd251e; Staf42; Tada1l"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1091
                     /gene="Tada1"
                     /gene_synonym="2900026B15Rik; D1Ertd251e; Staf42; Tada1l"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..2145
                     /gene="Tada1"
                     /gene_synonym="2900026B15Rik; D1Ertd251e; Staf42; Tada1l"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2126..2131
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tada1"
                     /gene_synonym="2900026B15Rik; D1Ertd251e; Staf42; Tada1l"
                     /note="hexamer: AATAAA"
     polyA_site      2145
                     /gene="Tada1"
                     /gene_synonym="2900026B15Rik; D1Ertd251e; Staf42; Tada1l"
                     /note="major polyA site"
ORIGIN      
        1 agagccgagc cgagccgagc cgagcggagc cgagccgagc cgagcggagc cgagccgagc
       61 cgagccgagc cgaaccgagc cgagccgagc cgaaccgagc cgagccgagc cgagtggaat
      121 cgagtcgagt cgagcctcca gcgtccggcg cgcaggcctt ccgccgcgtt gatctttcgg
      181 ttgctggtgg ccgtgggccg cgcggtctac ggtcgggctg aaagacgcgc gctgcaatgg
      241 cgacctttgt gagcgagctg gaggcagcca agaagaactt gagcgaggcg ctgggggaca
      301 acgtgaaaca atactgggcc aacctgaagt tgtggttcaa gcagaagatc agcaaggagg
      361 agttcgacct tgaagctcac agactcctca cacaggacaa tgtgcattct cacaatgact
      421 tcctcctggc catcctcaca cgttgtcaga ttttggtttc tacaccagag ggtgctggat
      481 ctttgccctg gacagggggc tctgcagcca agcctggaaa acccaagggc aagaaaaagc
      541 tttcttctgt tcgtcaaaaa tttgatcata ggttccagcc tcagaacccc ctctctggag
      601 ctcagcagtt cgtggcaaag gagccccagg gtgatgacga cttgaaactt tgttcacaca
      661 ccatgatgct tcccacgcga ggccaacttg aagggagaat gatcgtgact gcctatgagc
      721 acgggctgga caatgtcact gaggaggccg tgtctgccgt ggtctatgcc gtggagaatc
      781 acctcaaaga tattctgacc tcagttgtgt cgagaaggaa agcttaccgg gtacgggatg
      841 gtcattttaa atacgccttt gggagcaacg tgacgccaca gccatacctg aagaatagtg
      901 tggtggctta caacaacttg gttgaaggcc ctccagcctt ctctgctcca tgtgccaatc
      961 agagcccagc gtctcagcca caccccgacg atgctgagca gcaggctgca ttcctattgg
     1021 cctgctcggg ggacacgcta cctgcatctc tgcctccagt gaacatgtat gacctgtttg
     1081 aagctttgca ggtccacagg gaagtcattc ctacacatac tgtgtatgcc cttaacattg
     1141 aaaggatcat catgaaactc tggcacccca atcacgaaga gctacaacaa gacaaagtcc
     1201 accgccagcg cctggcagcc aaagaaggac ttttgctctg ctaaattaga atttgaagat
     1261 ttgggaccat tactaaatta attggttgct gaaaattgaa tgcttttgag tccacatttc
     1321 aaaactgaag tgtatagtgt atgtataacc tttcctatgg aaatgtgaca tttgagtgca
     1381 ttttgtgttg ctactgtgaa ggcattaata tgtctgactg atgacctgtg tgtctgtgtc
     1441 cccacgtata ggagcactca ttggtctgtg tctgagtagg gatcttaaga cacctgaggt
     1501 gtatctggtc tgtcagtaag ataggtgaca tcgtacaata aagatgctgt ggccgttcag
     1561 tcccatgatc agcaggacca ctgtgtgttc agtgatgtat gttctgtatc tggcagcgta
     1621 aactctgctt ttcctaaaga actatactct gcatattggt ggaatagcct agtgctcatc
     1681 agaatctgtt agtgactagt tagcaactgg agttcccaag caacccgctt tcactccaga
     1741 gagcaggatt tagctctctg cttcttgctt tgctttgatc cttgagtcca attcttagat
     1801 gtagttatcc ttacagaggg ttctgtaact tccttgttag ctgaccgaca agcttgttaa
     1861 tcctatagaa cgttttcatg aaatcttaca aactaatttt cccatttcta caaaatgtct
     1921 gttttatcct ttcaagtggt actatgaact tgtatctgac agtgttactg gtaaccaact
     1981 tgttttaaag ctatgttgct ttttactcat gtagtgttca tgggtgagat gtatagatgg
     2041 gttttatagg cctaaacagt ggatacatgt gaatgttttt gtgtgttcct atatctgaat
     2101 ttggttttgt attttaaaca tgacaaataa acattttggg agaaaaaaaa aaaaaaaaa
//
