LOCUS       NM_001010828            1038 bp    mRNA    linear   ROD 11-DEC-2024
DEFINITION  Mus musculus trace amine-associated receptor 6 (Taar6), mRNA.
ACCESSION   NM_001010828 XM_136993
VERSION     NM_001010828.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1038)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1038)
  AUTHORS   Guo,L., Cheng,J., Lian,S., Liu,Q., Lu,Y., Zheng,Y., Zhu,K.,
            Zhang,M., Kong,Y., Zhang,C., Rong,N., Zhuang,Y., Fang,G., Jiang,J.,
            Zhang,T., Han,X., Liu,Z., Xia,M., Liu,S., Zhang,L., Liberles,S.D.,
            Yu,X., Xu,Y., Yang,F., Li,Q. and Sun,J.P.
  TITLE     Structural basis of amine odorant perception by a mammal olfactory
            receptor
  JOURNAL   Nature 618 (7963), 193-200 (2023)
   PUBMED   37225986
REFERENCE   3  (bases 1 to 1038)
  AUTHORS   Vaganova,A.N., Katolikova,N.V., Murtazina,R.Z., Kuvarzin,S.R. and
            Gainetdinov,R.R.
  TITLE     Public Transcriptomic Data Meta-Analysis Demonstrates TAAR6
            Expression in the Mental Disorder-Related Brain Areas in Human and
            Mouse Brain
  JOURNAL   Biomolecules 12 (9), 1259 (2022)
   PUBMED   36139098
  REMARK    GeneRIF: Public Transcriptomic Data Meta-Analysis Demonstrates
            TAAR6 Expression in the Mental Disorder-Related Brain Areas in
            Human and Mouse Brain.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1038)
  AUTHORS   Fei,A., Wu,W., Tan,L., Tang,C., Xu,Z., Huo,X., Bao,H., Kong,Y.,
            Johnson,M., Hartmann,G., Talay,M., Yang,C., Riegler,C.,
            Herrera,K.J., Engert,F., Xie,X.S., Barnea,G., Liberles,S.D.,
            Yang,H. and Li,Q.
  TITLE     Coordination of two enhancers drives expression of olfactory trace
            amine-associated receptors
  JOURNAL   Nat Commun 12 (1), 3798 (2021)
   PUBMED   34145235
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1038)
  AUTHORS   Yoon,K.H., Ragoczy,T., Lu,Z., Kondoh,K., Kuang,D., Groudine,M. and
            Buck,L.B.
  TITLE     Olfactory receptor genes expressed in distinct lineages are
            sequestered in different nuclear compartments
  JOURNAL   Proc Natl Acad Sci U S A 112 (18), E2403-E2409 (2015)
   PUBMED   25897022
REFERENCE   6  (bases 1 to 1038)
  AUTHORS   Fleischer,J., Schwarzenbacher,K. and Breer,H.
  TITLE     Expression of trace amine-associated receptors in the Grueneberg
            ganglion
  JOURNAL   Chem Senses 32 (6), 623-631 (2007)
   PUBMED   17556730
REFERENCE   7  (bases 1 to 1038)
  AUTHORS   Liberles,S.D. and Buck,L.B.
  TITLE     A second class of chemosensory receptors in the olfactory
            epithelium
  JOURNAL   Nature 442 (7103), 645-650 (2006)
   PUBMED   16878137
  REMARK    GeneRIF: Previous studies reported TAAR expression in brain. This
            paper found TAAR expression only in olfactory epithelial cells and
            that each TAAR detects a unique set of amine ligands. TAARs seem to
            function as a family of chemosensory receptors for amines.
REFERENCE   8  (bases 1 to 1038)
  AUTHORS   Lindemann,L., Ebeling,M., Kratochwil,N.A., Bunzow,J.R., Grandy,D.K.
            and Hoener,M.C.
  TITLE     Trace amine-associated receptors form structurally and functionally
            distinct subfamilies of novel G protein-coupled receptors
  JOURNAL   Genomics 85 (3), 372-385 (2005)
   PUBMED   15718104
REFERENCE   9  (bases 1 to 1038)
  AUTHORS   Borowsky,B., Adham,N., Jones,K.A., Raddatz,R., Artymyshyn,R.,
            Ogozalek,K.L., Durkin,M.M., Lakhlani,P.P., Bonini,J.A.,
            Pathirana,S., Boyle,N., Pu,X., Kouranova,E., Lichtblau,H.,
            Ochoa,F.Y., Branchek,T.A. and Gerald,C.
  TITLE     Trace amines: identification of a family of mammalian G
            protein-coupled receptors
  JOURNAL   Proc Natl Acad Sci U S A 98 (16), 8966-8971 (2001)
   PUBMED   11459929
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY702330.1.
            
            On Jan 26, 2005 this sequence version replaced XM_136993.1.
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1038
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 11.4 cM"
     gene            1..1038
                     /gene="Taar6"
                     /gene_synonym="Gm228; taR-6"
                     /note="trace amine-associated receptor 6"
                     /db_xref="GeneID:215855"
                     /db_xref="MGI:MGI:2685074"
     CDS             1..1038
                     /gene="Taar6"
                     /gene_synonym="Gm228; taR-6"
                     /codon_start=1
                     /product="trace amine-associated receptor 6"
                     /protein_id="NP_001010828.1"
                     /db_xref="CCDS:CCDS23739.1"
                     /db_xref="GeneID:215855"
                     /db_xref="MGI:MGI:2685074"
                     /translation="MGSNSSPPTVLQLCYENVTGSCVKTPYSPGSRVILYAVFGFGAV
                     LAVFGNLMVMISILHFKQLHSPTNFLIASLACADFGVGISVMPFSMVRSIESCWYFGR
                     SFCTFHTCCDVAFCYSSLFHLSFISIDRYIAVTDPLVYPTKFTVSVSGICIGVSWILP
                     LVYSGAVFYTGVYDDGLEELSSALNCVGGCQVVVNQNWVLIDFLSFLIPTLVMIILYG
                     NIFLVARQQAKKIENIGSKTESSSESYKARVARRERKAAKTLGITVVAFMISWLPYSI
                     DSLVDAFMGFITPAYIYEICVWCAYYNSAMNPLIYALFYPWFKKAIKVIMSGQVFKNS
                     SATMNLFSEQI"
     exon            1..1038
                     /gene="Taar6"
                     /gene_synonym="Gm228; taR-6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgggcagta actcgtctcc gcccaccgtc ctgcagctct gctatgagaa tgtgaccggg
       61 tcttgtgtga aaacccccta ctctcctggg tcgagggtca tcctctatgc agtctttggc
      121 tttggggctg tgctggcagt gtttggaaac ctcatggtga tgatatccat cctccatttc
      181 aagcagctgc actctcccac caatttcctc attgcatcct tggcctgtgc tgactttggt
      241 gtgggcatct ctgtgatgcc cttcagcatg gtcaggtcca tcgagagctg ctggtacttt
      301 ggtagaagtt tctgcacttt ccacacctgc tgtgatgtgg cgttctgtta ctcttctctc
      361 ttccacctga gcttcatctc catcgacagg tacatcgctg tcacggaccc tctggtctat
      421 cccaccaagt tcacggtgtc tgtgtctgga atttgcatcg gcgtctcctg gattctgccc
      481 ctggtgtaca gcggcgctgt gttctacaca ggggtttatg atgacggcct ggaggaatta
      541 tccagtgccc tcaactgcgt agggggctgt caggtagttg tgaatcagaa ctgggtgctg
      601 atagattttc tttccttctt aatacctaca cttgttatga taattctgta tggtaatatt
      661 tttctggtag ctagacaaca ggctaaaaag atagaaaata ttgggagcaa aacagaatca
      721 tcctctgaga gctacaaagc cagagtggcg agaagagaaa gaaaagcagc caaaaccctg
      781 gggattaccg tggtagcatt catgatatca tggttgccct acagcattga ttcattagtt
      841 gatgctttta tgggcttcat cacccctgcc tacatttatg aaatctgtgt ttggtgtgct
      901 tattacaact cagccatgaa ccctctgatc tacgctttat tttatccatg gtttaagaaa
      961 gctattaagg ttattatgag tggccaggtg ttcaagaaca gctcagccac tatgaacttg
     1021 ttctctgagc aaatataa
//
