LOCUS       NM_001009574            1014 bp    mRNA    linear   ROD 11-DEC-2024
DEFINITION  Mus musculus trace amine-associated receptor 5 (Taar5), mRNA.
ACCESSION   NM_001009574 XM_136992
VERSION     NM_001009574.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1014)
  AUTHORS   Guo,L., Cheng,J., Lian,S., Liu,Q., Lu,Y., Zheng,Y., Zhu,K.,
            Zhang,M., Kong,Y., Zhang,C., Rong,N., Zhuang,Y., Fang,G., Jiang,J.,
            Zhang,T., Han,X., Liu,Z., Xia,M., Liu,S., Zhang,L., Liberles,S.D.,
            Yu,X., Xu,Y., Yang,F., Li,Q. and Sun,J.P.
  TITLE     Structural basis of amine odorant perception by a mammal olfactory
            receptor
  JOURNAL   Nature 618 (7963), 193-200 (2023)
   PUBMED   37225986
REFERENCE   2  (bases 1 to 1014)
  AUTHORS   Maggi,S., Bon,C., Gustincich,S., Tucci,V., Gainetdinov,R.R. and
            Espinoza,S.
  TITLE     Improved cognitive performance in trace amine-associated receptor 5
            (TAAR5) knock-out mice
  JOURNAL   Sci Rep 12 (1), 14708 (2022)
   PUBMED   36038766
  REMARK    GeneRIF: Improved cognitive performance in trace amine-associated
            receptor 5 (TAAR5) knock-out mice.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1014)
  AUTHORS   Kalinina,D.S., Ptukha,M.A., Goriainova,A.V., Merkulyeva,N.S.,
            Kozlova,A.A., Murtazina,R.Z., Shemiakova,T.S., Kuvarzin,S.R.,
            Vaganova,A.N., Volnova,A.B., Gainetdinov,R.R. and Musienko,P.E.
  TITLE     Role of the trace amine associated receptor 5 (TAAR5) in the
            sensorimotor functions
  JOURNAL   Sci Rep 11 (1), 23092 (2021)
   PUBMED   34845253
  REMARK    GeneRIF: Role of the trace amine associated receptor 5 (TAAR5) in
            the sensorimotor functions.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1014)
  AUTHORS   Zhukov,I.S., Kubarskaya,L.G., Karpova,I.V., Vaganova,A.N.,
            Karpenko,M.N. and Gainetdinov,R.R.
  TITLE     Minor Changes in Erythrocyte Osmotic Fragility in Trace
            Amine-Associated Receptor 5 (TAAR5) Knockout Mice
  JOURNAL   Int J Mol Sci 22 (14), 7307 (2021)
   PUBMED   34298937
  REMARK    GeneRIF: Minor Changes in Erythrocyte Osmotic Fragility in Trace
            Amine-Associated Receptor 5 (TAAR5) Knockout Mice.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1014)
  AUTHORS   Fei,A., Wu,W., Tan,L., Tang,C., Xu,Z., Huo,X., Bao,H., Kong,Y.,
            Johnson,M., Hartmann,G., Talay,M., Yang,C., Riegler,C.,
            Herrera,K.J., Engert,F., Xie,X.S., Barnea,G., Liberles,S.D.,
            Yang,H. and Li,Q.
  TITLE     Coordination of two enhancers drives expression of olfactory trace
            amine-associated receptors
  JOURNAL   Nat Commun 12 (1), 3798 (2021)
   PUBMED   34145235
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1014)
  AUTHORS   Ferrero,D.M., Wacker,D., Roque,M.A., Baldwin,M.W., Stevens,R.C. and
            Liberles,S.D.
  TITLE     Agonists for 13 trace amine-associated receptors provide insight
            into the molecular basis of odor selectivity
  JOURNAL   ACS Chem Biol 7 (7), 1184-1189 (2012)
   PUBMED   22545963
REFERENCE   7  (bases 1 to 1014)
  AUTHORS   Fleischer,J., Schwarzenbacher,K. and Breer,H.
  TITLE     Expression of trace amine-associated receptors in the Grueneberg
            ganglion
  JOURNAL   Chem Senses 32 (6), 623-631 (2007)
   PUBMED   17556730
REFERENCE   8  (bases 1 to 1014)
  AUTHORS   Liberles,S.D. and Buck,L.B.
  TITLE     A second class of chemosensory receptors in the olfactory
            epithelium
  JOURNAL   Nature 442 (7103), 645-650 (2006)
   PUBMED   16878137
  REMARK    GeneRIF: Previous studies reported TAAR expression in brain. This
            paper found TAAR expression only in olfactory epithelial cells and
            that each TAAR detects a unique set of amine ligands. TAARs seem to
            function as a family of chemosensory receptors for amines.
REFERENCE   9  (bases 1 to 1014)
  AUTHORS   Lindemann,L., Ebeling,M., Kratochwil,N.A., Bunzow,J.R., Grandy,D.K.
            and Hoener,M.C.
  TITLE     Trace amine-associated receptors form structurally and functionally
            distinct subfamilies of novel G protein-coupled receptors
  JOURNAL   Genomics 85 (3), 372-385 (2005)
   PUBMED   15718104
REFERENCE   10 (bases 1 to 1014)
  AUTHORS   Borowsky,B., Adham,N., Jones,K.A., Raddatz,R., Artymyshyn,R.,
            Ogozalek,K.L., Durkin,M.M., Lakhlani,P.P., Bonini,J.A.,
            Pathirana,S., Boyle,N., Pu,X., Kouranova,E., Lichtblau,H.,
            Ochoa,F.Y., Branchek,T.A. and Gerald,C.
  TITLE     Trace amines: identification of a family of mammalian G
            protein-coupled receptors
  JOURNAL   Proc Natl Acad Sci U S A 98 (16), 8966-8971 (2001)
   PUBMED   11459929
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY702329.1.
            
            On Jan 13, 2005 this sequence version replaced XM_136992.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1014
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 11.4 cM"
     gene            1..1014
                     /gene="Taar5"
                     /gene_synonym="Gm227; taR-5"
                     /note="trace amine-associated receptor 5"
                     /db_xref="GeneID:215854"
                     /db_xref="MGI:MGI:2685073"
     CDS             1..1014
                     /gene="Taar5"
                     /gene_synonym="Gm227; taR-5"
                     /note="mTaar5; trimethylamine receptor"
                     /codon_start=1
                     /product="trace amine-associated receptor 5"
                     /protein_id="NP_001009574.1"
                     /db_xref="CCDS:CCDS23738.1"
                     /db_xref="GeneID:215854"
                     /db_xref="MGI:MGI:2685073"
                     /translation="MRAVLLPGSGEQPTAFCYQVNGSCPRTVHPLAIQVVIYLACAVG
                     VLITVLGNLFVVFAVSYFKVLHTPTNFLLLSLALADMLLGLLVLPLSTVRSVESCWFF
                     GDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRTALRYIVAGWG
                     IPAAYTAFFLYTDVVERALSQWLEEMPCVGSCQLLFNKFWGWLNFPAFFVPCLIMISL
                     YLKIFVVATRQAQQIRTLSQSLAGAVKRERKAAKTLGIAVGIYLVCWLPFTVDTLVDS
                     LLNFITPPLVFDIFIWFAYFNSACNPIIYVFSYRWFRKALKLLLSREIFSPRTPTVDL
                     YHD"
     exon            1..1014
                     /gene="Taar5"
                     /gene_synonym="Gm227; taR-5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgagagctg tcctcctccc gggctctgga gagcagccta cagcgttctg ctaccaggtg
       61 aatgggtctt gccccaggac agtccacccg ctggccatcc aggtcgtcat ctatctggcc
      121 tgcgcagtgg gtgtgctgat cacagtcctg gggaatttgt ttgtggtgtt tgcagtgtcc
      181 tactttaaag tgctccacac gcccaccaac ttcctgctgc tctccctggc cctggcagac
      241 atgttgctag gtctgctggt gctgcccctg agcacagtcc gctctgtgga gagctgctgg
      301 ttctttggag acttcctgtg ccgtctgcat acctatctgg acacgctgtt ctgtctcacc
      361 tccatcttcc atctctgttt tatttccatt gaccgtcatt gtgccatctg tgaccccctg
      421 ctctatccct ccaagttcac agtcaggaca gccctccgct acatcgtggc agggtggggg
      481 ataccagcag cctacactgc cttcttcctc tacacagatg tggtagagag agcactcagc
      541 cagtggctag aagagatgcc ttgtgtgggc agctgccagc tgctgttcaa taagttctgg
      601 ggttggttaa acttccctgc attttttgtt ccctgcctaa tcatgatcag cttgtacctg
      661 aagatctttg tggtcgccac caggcaggct cagcagatca gaactctgag ccaaagcttg
      721 gctggggctg tcaagcggga aagaaaagct gccaagacgc tgggcattgc tgtgggcatc
      781 taccttgtgt gttggcttcc cttcactgtt gacacactag tggacagcct tcttaacttc
      841 atcaccccac ccctggtctt tgacatcttt atctggtttg cttatttcaa ttcagcctgt
      901 aatcccatca tctacgtctt ctcctaccgg tggtttagga aggcactgaa actgctcctg
      961 agccgggaga tcttctcacc aaggacaccg actgttgatt tataccatga ctga
//
