LOCUS       NM_001007266            1020 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus trace amine-associated receptor 2 (Taar2), mRNA.
ACCESSION   NM_001007266 XM_136990
VERSION     NM_001007266.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1020)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1020)
  AUTHORS   Efimova,E.V., Kuvarzin,S.R., Mor,M.S., Katolikova,N.V.,
            Shemiakova,T.S., Razenkova,V., Ptukha,M., Kozlova,A.A.,
            Murtazina,R.Z., Smirnova,D., Veshchitskii,A.A., Merkulyeva,N.S.,
            Volnova,A.B., Musienko,P.E., Korzhevskii,D.E., Budygin,E.A. and
            Gainetdinov,R.R.
  TITLE     Trace Amine-Associated Receptor 2 Is Expressed in the Limbic Brain
            Areas and Is Involved in Dopamine Regulation and Adult Neurogenesis
  JOURNAL   Front Behav Neurosci 16, 847410 (2022)
   PUBMED   35431833
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1020)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 1020)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 1020)
  AUTHORS   Fleischer,J., Schwarzenbacher,K. and Breer,H.
  TITLE     Expression of trace amine-associated receptors in the Grueneberg
            ganglion
  JOURNAL   Chem Senses 32 (6), 623-631 (2007)
   PUBMED   17556730
REFERENCE   6  (bases 1 to 1020)
  AUTHORS   Liberles,S.D. and Buck,L.B.
  TITLE     A second class of chemosensory receptors in the olfactory
            epithelium
  JOURNAL   Nature 442 (7103), 645-650 (2006)
   PUBMED   16878137
  REMARK    GeneRIF: Previous studies reported TAAR expression in brain. This
            paper found TAAR expression only in olfactory epithelial cells and
            that each TAAR detects a unique set of amine ligands. TAARs seem to
            function as a family of chemosensory receptors for amines.
REFERENCE   7  (bases 1 to 1020)
  AUTHORS   Lindemann,L., Ebeling,M., Kratochwil,N.A., Bunzow,J.R., Grandy,D.K.
            and Hoener,M.C.
  TITLE     Trace amine-associated receptors form structurally and functionally
            distinct subfamilies of novel G protein-coupled receptors
  JOURNAL   Genomics 85 (3), 372-385 (2005)
   PUBMED   15718104
REFERENCE   8  (bases 1 to 1020)
  AUTHORS   Vassilatis,D.K., Hohmann,J.G., Zeng,H., Li,F., Ranchalis,J.E.,
            Mortrud,M.T., Brown,A., Rodriguez,S.S., Weller,J.R., Wright,A.C.,
            Bergmann,J.E. and Gaitanaris,G.A.
  TITLE     The G protein-coupled receptor repertoires of human and mouse
  JOURNAL   Proc Natl Acad Sci U S A 100 (8), 4903-4908 (2003)
   PUBMED   12679517
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY702326.1.
            
            On Dec 16, 2004 this sequence version replaced XM_136990.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY702326.1, BC139118.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1020
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 11.4 cM"
     gene            1..1020
                     /gene="Taar2"
                     /gene_synonym="Gm224; Gm225; Gpr58; Tarr2"
                     /note="trace amine-associated receptor 2"
                     /db_xref="GeneID:209512"
                     /db_xref="MGI:MGI:2685071"
     CDS             1..1020
                     /gene="Taar2"
                     /gene_synonym="Gm224; Gm225; Gpr58; Tarr2"
                     /note="G protein-coupled receptor 58; taR-2; trace amine
                     receptor 2; mTaar2"
                     /codon_start=1
                     /product="trace amine-associated receptor 2"
                     /protein_id="NP_001007267.1"
                     /db_xref="CCDS:CCDS35869.1"
                     /db_xref="GeneID:209512"
                     /db_xref="MGI:MGI:2685071"
                     /translation="MASFEAQQETFDCSEYGNGSCPENERSLGVRAAMYSLMACAIFI
                     TIFGNLAMIISISYFKQLHTPTNLLILSMAVTDFLLGFTIMPYSMVRSVENCWYFGLT
                     FCKIHYSFDLMLSITSIFHLCSVAVDRFYAICHPLHYCTKMTIPVVRRLLLVCWSVPG
                     AFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFVAGFFTPSSMMVGIYG
                     KIFAVSKKHARVIDNLPENQNNQMRKDKKAAKTLGIVMGVFLLCWFPCFFTILLDPFL
                     NFSTPAVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSHFHNTNLFT
                     QKETE"
     exon            1..24
                     /gene="Taar2"
                     /gene_synonym="Gm224; Gm225; Gpr58; Tarr2"
                     /inference="alignment:Splign:2.1.0"
     exon            25..1020
                     /gene="Taar2"
                     /gene_synonym="Gm224; Gm225; Gpr58; Tarr2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcatctt ttgaagccca gcaggaaacc tttgattgtt cagagtacgg aaatggatct
       61 tgcccagaga atgaaagatc tctcggcgtc cgagctgcca tgtactcgtt gatggcctgc
      121 gccatattca tcacgatctt tggcaacctg gccatgatca tttccatttc ctacttcaaa
      181 cagcttcaca caccgaccaa cctcctcatt ctctccatgg ccgtcaccga cttccttctc
      241 ggattcacca tcatgccata tagtatggtc aggtcagtgg aaaactgctg gtatttcgga
      301 cttacgtttt gcaagatcca ttatagcttc gacctgatgc ttagcataac gtccattttc
      361 cacctttgct cggtggccgt cgatagattt tatgccatct gtcacccttt gcattattgc
      421 accaaaatga ctatcccggt cgttaggcgg ctgctgctcg tctgctggtc agtccccggg
      481 gcgtttgcct ttggggtggt cttctccgag gcttacgctg atggaattga aggctatgac
      541 attttggttg catgttccag ttcctgccca gtcatgttca acaagctatg ggggaccacc
      601 ttgtttgtgg caggcttttt cactcctagc tcgatgatgg tggggattta cggcaaaatt
      661 ttcgctgtat ccaaaaaaca cgctcgcgta attgacaact tgccagaaaa tcaaaacaat
      721 caaatgagga aggacaaaaa agcagccaaa actttaggga tagtgatggg tgttttctta
      781 ttgtgttggt ttccatgttt cttcaccatc ctgttagatc cgtttctgaa tttctctacg
      841 cctgcagttc tgtttgatgc cttaacatgg ttcggttatt ttaattccac atgtaatccc
      901 ttaatttatg gtttcttcta cccttggttt cgcagagcac tcaagtacat tttactgggt
      961 aaaattttca gctcgcattt ccataatact aatttgttta ctcaaaaaga aacagaatag
//
