LOCUS       NM_001161832            1755 bp    mRNA    linear   ROD 09-DEC-2020
DEFINITION  Mus musculus brachyury 2 (T2), mRNA.
ACCESSION   NM_001161832
VERSION     NM_001161832.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1755)
  AUTHORS   Wu JI, Centilli MA, Vasquez G, Young S, Scolnick J, Durfee LA,
            Spearow JL, Schwantz SD, Rennebeck G and Artzt K.
  TITLE     Tint maps to mouse chromosome 6 and may interact with a notochordal
            enhancer of Brachyury
  JOURNAL   Genetics 177 (2), 1151-1161 (2007)
   PUBMED   17954925
  REMARK    GeneRIF: tint interacts with brachyury 2 but not with brachyury T1;
            T2 may be part of the T1 regulatory region through direct or
            indirect participation of tint
            GeneRIF: An unlinked modifier of Brachyury (T) called tint,
            interacts with T2 but not with T1. Highly conserved genomic
            sequences between mice and humans map to the distal end of T2. T2
            may embed the long sought mammalian notochord enhancer of
            Brachyury.
REFERENCE   2  (bases 1 to 1755)
  AUTHORS   Rennebeck G, Lader E, Fujimoto A, Lei EP and Artzt K.
  TITLE     Mouse Brachyury the Second (T2) is a gene next to classical T and a
            candidate gene for tct
  JOURNAL   Genetics 150 (3), 1125-1131 (1998)
   PUBMED   9799264
REFERENCE   3  (bases 1 to 1755)
  AUTHORS   Rennebeck GM, Lader E, Chen Q, Bohm RA, Cai ZS, Faust C, Magnuson
            T, Pease LR and Artzt K.
  TITLE     Is there a Brachyury the Second? Analysis of a transgenic mutation
            involved in notochord maintenance in mice
  JOURNAL   Dev Biol 172 (1), 206-217 (1995)
   PUBMED   7589801
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC164431.2 and
            AC154579.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849387,
                              SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-108               AC164431.2         174359-174466
            109-183             AC154579.3         5842-5916
            184-322             AC154579.3         7410-7548
            323-423             AC154579.3         8717-8817
            424-537             AC154579.3         13267-13380
            538-621             AC154579.3         28324-28407
            622-728             AC154579.3         29557-29663
            729-789             AC154579.3         33687-33747
            790-1016            AC154579.3         34500-34726
            1017-1131           AC154579.3         38114-38228
            1132-1755           AC154579.3         38611-39234
FEATURES             Location/Qualifiers
     source          1..1755
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 4.92 cM"
     gene            1..1755
                     /gene="T2"
                     /gene_synonym="brachyury2"
                     /note="brachyury 2"
                     /db_xref="GeneID:21331"
                     /db_xref="MGI:MGI:104658"
     CDS             1..1182
                     /gene="T2"
                     /gene_synonym="brachyury2"
                     /note="brachyury the second"
                     /codon_start=1
                     /product="brachyury 2"
                     /protein_id="NP_001155304.1"
                     /db_xref="CCDS:CCDS88987.1"
                     /db_xref="GeneID:21331"
                     /db_xref="MGI:MGI:104658"
                     /translation="MAQILRDHFKTPKKHRGCHTQVEDKEKAAQQTLPEQSQPEAWSA
                     SPPKASTRFPSRSNAYLIIGLQNELTKCGILKNMSDDEDFWKLVQEEALGVGTKEKLQ
                     KIKLKLMNPRPWPPAASRRRETEMLVSSDQDSGARQGTQDHPGREQEVVEDGPEKERI
                     KQGPHQPGLDPPKHRGDTASLLARLTEWRKRCQQHGAAQRLHRGPEESKTMCKTRTDS
                     QSKMYLSRLYRMYSTSLANMEFSRKLLERDGRFADMDAEHRARSLLDYMVPRERTQAD
                     VPPRERTQADVPPRELEEEDSPTPEQQPQAGPALRFLKCQSPESPQRRPHLKTGRHQV
                     TLCGTSKLSEHERGTLAPARRTTDPRPTAPLTLAHVIQTHPVVEAKTASRYWVNNVDE
                     E"
     exon            1..108
                     /gene="T2"
                     /gene_synonym="brachyury2"
                     /inference="alignment:Splign:2.1.0"
     exon            109..183
                     /gene="T2"
                     /gene_synonym="brachyury2"
                     /inference="alignment:Splign:2.1.0"
     exon            184..322
                     /gene="T2"
                     /gene_synonym="brachyury2"
                     /inference="alignment:Splign:2.1.0"
     exon            323..423
                     /gene="T2"
                     /gene_synonym="brachyury2"
                     /inference="alignment:Splign:2.1.0"
     exon            424..537
                     /gene="T2"
                     /gene_synonym="brachyury2"
                     /inference="alignment:Splign:2.1.0"
     exon            538..621
                     /gene="T2"
                     /gene_synonym="brachyury2"
                     /inference="alignment:Splign:2.1.0"
     exon            622..728
                     /gene="T2"
                     /gene_synonym="brachyury2"
                     /inference="alignment:Splign:2.1.0"
     exon            729..789
                     /gene="T2"
                     /gene_synonym="brachyury2"
                     /inference="alignment:Splign:2.1.0"
     exon            790..1016
                     /gene="T2"
                     /gene_synonym="brachyury2"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..1131
                     /gene="T2"
                     /gene_synonym="brachyury2"
                     /inference="alignment:Splign:2.1.0"
     exon            1132..1755
                     /gene="T2"
                     /gene_synonym="brachyury2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcccaga tcttgagaga ccattttaaa acgccaaaga aacacagggg gtgtcacacc
       61 caagtggagg acaaagagaa ggcagcacag cagaccttgc cggaacagtc gcagcccgaa
      121 gcttggtcag catccccgcc caaggcttca accaggttcc cttccaggtc caacgcctac
      181 ctgattatag ggttgcaaaa cgagctgacc aaatgtggga tcttgaagaa catgagcgac
      241 gacgaggatt tctggaaact ggttcaggag gaagctcttg gagtgggaac taaagaaaag
      301 ctccagaaga taaaacttaa gttgatgaat cccaggccct ggccaccagc tgcttccagg
      361 agaagggaga ccgagatgct ggtcagcagt gatcaagaca gtggggcacg ccagggaaca
      421 caggaccatc cagggagaga acaggaagtt gtggaggatg gcccggagaa ggagaggata
      481 aaacagggcc cgcaccaacc tggcttggat ccacccaagc atcgagggga cacagcgagt
      541 cttctcgctc ggctcacgga atggagaaaa agatgccaac agcatggagc tgcccagagg
      601 ctgcatcgag gacctgagga gagcaagact atgtgtaaga caaggacgga ttcccaaagc
      661 aagatgtatc ttagccggtt gtatcggatg tattccacct cccttgctaa catggaattc
      721 tccagaaaac tgctggaaag agatggccgc tttgcagaca tggatgctga gcacagggcc
      781 cgaagcctgc tggattacat ggtcccaaga gaacgtacac aggcagatgt tccaccaaga
      841 gaacgtacac aggcagatgt tccaccaagg gaactagagg aggaggactc cccaacccct
      901 gagcagcagc ctcaagcagg acctgccctc cgatttctga agtgccagag cccagaaagt
      961 ccacagagac gtccccacct gaagacagga agacaccaag tgaccctgtg tggcacgagc
     1021 aagctctccg aacacgagag gggcacactt gctcctgcca ggaggaccac agatcccaga
     1081 cctacagcac ccctgaccct tgcacacgtg atccagaccc atcctgtggt ggaggccaag
     1141 acagcaagtc gatactgggt gaacaatgtg gatgaagaat aagttttttt tttgtctttt
     1201 ttttttttaa acagtcatta gataaagtcc aaacaggata tgacagcttt ctttttcttt
     1261 gagtctgcat tatgataagc agcgaggtag gtatccggta gagatgctcg tgcctgacac
     1321 gagatgcctg gcacttcgtt ctttcattat tattttttaa gatttattta tttattatat
     1381 gtaagtacac tgtagctgtc ttcagactcg tcagaagagg gcatcagacc tcattatgga
     1441 tggttgtgag tcaccatgtg gttgctggga tttgaacgca ggactttagg aagaacactc
     1501 agtgctctta accgctgagc catctctcca gcccttgttc tttcgttgta aaggtgacac
     1561 catcatgcag agcccgaacc gtgaatttgg atgatggaga cagtcaggca ggcagcacag
     1621 tgggcagcag cgctgagcag actcagacat gaggctccag cccatggcta gtcacttctt
     1681 ctgactcatg gtccttctgc ctggtgctct ctttgcagca tcttaaataa aataagcttg
     1741 ttttctttct taaaa
//
