LOCUS       NM_198170              10958 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus SZT2 subunit of KICSTOR complex (Szt2), mRNA.
ACCESSION   NM_198170 XM_001477657 XM_001481275
VERSION     NM_198170.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 10958)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 10958)
  AUTHORS   Yin,N., Jin,G., Ma,Y., Zhao,H., Zhang,G., Li,M.O. and Peng,M.
  TITLE     SZT2 maintains hematopoietic stem cell homeostasis via
            nutrient-mediated mTORC1 regulation
  JOURNAL   J Clin Invest 132 (20), e146272 (2022)
   PUBMED   36250465
  REMARK    GeneRIF: SZT2 maintains hematopoietic stem cell homeostasis via
            nutrient-mediated mTORC1 regulation.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 10958)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 10958)
  AUTHORS   Peng,M., Yin,N. and Li,M.O.
  TITLE     SZT2 dictates GATOR control of mTORC1 signalling
  JOURNAL   Nature 543 (7645), 433-437 (2017)
   PUBMED   28199315
  REMARK    GeneRIF: SZT2 has a central role in dictating GATOR-dependent
            nutrient sensing by promoting lysosomal localization of
            SZT2-orchestrated GATOR complex, and reveal an unexpected function
            of lysosome-located GATOR2 in suppressing mTORC1 signalling through
            SESN recruitment
            Erratum:[Nature. 2018 Jun;558(7710):E2. doi:
            10.1038/s41586-018-0114-2.. PMID: 29769712]
REFERENCE   5  (bases 1 to 10958)
  AUTHORS   Wolfson,R.L., Chantranupong,L., Wyant,G.A., Gu,X., Orozco,J.M.,
            Shen,K., Condon,K.J., Petri,S., Kedir,J., Scaria,S.M.,
            Abu-Remaileh,M., Frankel,W.N. and Sabatini,D.M.
  TITLE     KICSTOR recruits GATOR1 to the lysosome and is necessary for
            nutrients to regulate mTORC1
  JOURNAL   Nature 543 (7645), 438-442 (2017)
   PUBMED   28199306
  REMARK    GeneRIF: in mice that lack SZT2, mTORC1 signalling is increased in
            several tissues, including in neurons in the brain
REFERENCE   6  (bases 1 to 10958)
  AUTHORS   Toutzaris,D., Lewerenz,J., Albrecht,P., Jensen,L.T., Letz,J.,
            Geerts,A., Golz,S. and Methner,A.
  TITLE     A novel giant peroxisomal superoxide dismutase motif-containing
            protein
  JOURNAL   Free Radic Biol Med 48 (6), 811-820 (2010)
   PUBMED   20045724
REFERENCE   7  (bases 1 to 10958)
  AUTHORS   Frankel,W.N., Yang,Y., Mahaffey,C.L., Beyer,B.J. and O'Brien,T.P.
  TITLE     Szt2, a novel gene for seizure threshold in mice
  JOURNAL   Genes Brain Behav 8 (5), 568-576 (2009)
   PUBMED   19624305
  REMARK    GeneRIF: While the biological function of Szt2 remains unknown, its
            high conservation, unique structure and effect on seizure threshold
            suggest that it serves an important role in the central nervous
            system.
REFERENCE   8  (bases 1 to 10958)
  AUTHORS   Church,D.M., Goodstadt,L., Hillier,L.W., Zody,M.C., Goldstein,S.,
            She,X., Bult,C.J., Agarwala,R., Cherry,J.L., DiCuccio,M.,
            Hlavina,W., Kapustin,Y., Meric,P., Maglott,D., Birtle,Z.,
            Marques,A.C., Graves,T., Zhou,S., Teague,B., Potamousis,K.,
            Churas,C., Place,M., Herschleb,J., Runnheim,R., Forrest,D.,
            Amos-Landgraf,J., Schwartz,D.C., Cheng,Z., Lindblad-Toh,K.,
            Eichler,E.E. and Ponting,C.P.
  CONSRTM   Mouse Genome Sequencing Consortium
  TITLE     Lineage-specific biology revealed by a finished genome assembly of
            the mouse
  JOURNAL   PLoS Biol 7 (5), e1000112 (2009)
   PUBMED   19468303
REFERENCE   9  (bases 1 to 10958)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   10 (bases 1 to 10958)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from FJ998170.1 and CJ191816.1.
            
            On Aug 6, 2011 this sequence version replaced NM_198170.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FJ998170.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10953             FJ998170.1         1-10953
            10954-10958         CJ191816.1         474-478
FEATURES             Location/Qualifiers
     source          1..10958
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 54.61 cM"
     gene            1..10958
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /note="SZT2 subunit of KICSTOR complex"
                     /db_xref="GeneID:230676"
                     /db_xref="MGI:MGI:3033336"
     exon            1..101
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..10370
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /note="Seizure threshold 2 protein; Transcript increased
                     in glutamate resistance; seaizure threshold 2"
                     /codon_start=1
                     /product="KICSTOR complex protein SZT2"
                     /protein_id="NP_937813.3"
                     /db_xref="CCDS:CCDS51283.1"
                     /db_xref="GeneID:230676"
                     /db_xref="MGI:MGI:3033336"
                     /translation="MASERPEPEVEEAGQVFLLMKKDYRISRNVRLAWFLNHLHQTVQ
                     ATPQELLLQSEQELEVLSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIELDL
                     SPSTGIVDDSTGEILFDEVFHALSRCLGGLLRPFRVPGSCINFQPEIYVTIQAYSSII
                     GLQSHQVLVQGCLLDPSQREAFLQQVYEQLCLFEDKVATMLQQQYEPQGQAEDQSPES
                     GESLGRKVGVSMVTADLGLVSMIRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCE
                     TLLNQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGSYLSTCPETEPG
                     NLGLTVYHRAFLLYSFLRSGEALNPEYYCGSQHRLFNEHLVSASSNPALALRRKKHTE
                     KEVPADLVSTVSVRLREGYSVREVTLAKGGSQLEVKLVLLWKHNMRIEYVAVAPWPLE
                     PEGPRGTRVEVTMEGGYDILHDVSCALRQPIRSLYRTHVIRRFWNTLQSINQTDQMLA
                     HLQSFSSVPEHFTLPDSTKSGVPLFYIPPGSSTPVLSLQHSGSDSSHAQFAAYWKPVL
                     SMDANSWQRWLHMHRLVLILEHDTPLPKHLHTPGSNGRYSTIQCRISHSSLTSLLRDW
                     SSFVLVEGYSYVKLLSSAPDQPPSSFYMVRIISKTPCMVLRLGFPIGTPAQARHKIVS
                     GLKEEILRLRFPHRVQSKEPTPKVKRKGLGGVGGSSPSKSPPTLGPQQALSDRPCLVV
                     LHKPLDKLLIRYEKLPLDYRAPFLLTLEPPGPLPLVSGRSASSSLASLSRYLYHRRWL
                     WSVPSGLAPTLPLSATAQLLSVLTEVRLSEGFHFACSGEGIINMVLELPVQNEPLGQA
                     AAEEKHTCVVQYILFPPHSTSTKDSFSTDDDNDVEVEALEGDSELNLVTEVWVEPQYG
                     RVGPGPENWKHLQDLTYSEIPQALHPRDAACIGSLLTFEYLIQLCQSKEWGPLPPEPR
                     LSDGLDQRGDTCVHEIPFHFDLLGLLPQCQQLQMFFLLLSREPEGVPLAEGPCPTNDM
                     VLCLLHSCLGQELSDREIPLTPADQAAFLNEVLRRSLRDPGPEGPPVGGHAVAKDRAG
                     NSTQASGDSTLPSQSVVIPGVLRSSISAQPPQWHCYARLLGPQHVFLTFLPATFSDVQ
                     HLTAYGLESSFQEETKPKLGDWSGAPSLKDPGATGTKATESQVPTLSVTLASDSAQDS
                     GEPSTPSCQDLAANSGRQAPQTEGADGPRTRCPVYIYSCSLEALREQMVGLQPPQAPR
                     DLIFRAQDLDHPSSSSAWMEPRCKEAATHCALLQEHAQRCFVRGLFRSLQQAQSVTCQ
                     DLLTAVDACEELLQEIDITSFLLALCGHTWGLPHAPPSPGPLSPGPFSSSIEEGPEPR
                     ERAILVSESSIETEDLSEPEFQSSRVSGNLDPGPEISLTDVCQLRGEAHDALHSLIQE
                     KFLEISRLHFRTVPSNPHYFFYCPPSSRREDEGPRDTVDRKISDLEFSEAELVGEEGD
                     TSACCVVTESDPELEVEYRESREPDLGPAGLDSASLSDADTVNPDEDSFSILGGDSPT
                     GPDSLMHDLPPLFLHLTCSVRLRGQHSSVPVCSLPTCLGQVLSSLEGPPIGGRVPLRD
                     LSITLDVFVLTLPLEVELPPASDPQHHRSTSESSASFPRSPGQPSSLRSDDGLGPPLP
                     PPEEERHPGLSSLAMPHRLAIESTMNEIRWLLEDEMVGALRRGGIPQSPALHRAAAHI
                     HSSSGRPTCLRQAPPLSFVFGPERSLTQFKEEFRRLHLPGHVLLEDPDSGFFFVAAGQ
                     QPGVLHGEPPSAAWAWHNHEDRAEDAEGEVLTASPQVPGSLEDSEGTPLISLPSLSQG
                     GSQPGPSRGLSLMSSQGSVDSDHLGYDGGSSGSDSEGPGETLGEKALFTLRTPPGPAP
                     PQPSLPVLPGPSLPDFWLIVRILQDRVEVYAHARSLSREDGGPGAECRHLQQFLVRRV
                     GEICREVNQRLLLQDLHDSHVCNSLLVAESEEDLWRSETPFHSRQRAVLPSDDFAADE
                     SCAPRGYLAATMQFVPGHFSCDVVWGTVIRVHSRLKMGPSMGVSRAIQALRSVLNAFS
                     VVNRKNMFVYQERATKAVYYLRLLETSCSDRPWEGDTLPPSLALSRSQEPISSEDSVA
                     PRSPLDMASSRSSDAVRPVGQVDRHIQLLVHGVGQAGPEITDELVRVLRRRLDEATLD
                     IITVMLVRNCKLTPADVEFIQPPGSLPSEVLHLVLPPSCRPCLPALAWYLRQNLLTFL
                     HSPKYTDSNSRNHFQHPLPAQGGLPDLDIYLYNKPGGQGTGGKGVACITLAFVEEGGT
                     PISLASWPPSSPGPPDPLREEEFEQLTQVIRCPNTLDSCSAQDGSPRLRLDVWEKGNI
                     SIVQLEEKLRAAARQALADAIMELRLLPASLCTEDIPPGSLKSGPLDTKSPACRANTF
                     PCTPVSGEPVTPPSKAGRRSFWDMLSKTEAGDLGSPKTTDDIVLDRPEDTRGRRRHKT
                     ENVRTPGGSERAPGPDSGAQRQRRRTTQLEEGEVGTLHPVFARVIQRWMGFMVQIGCA
                     SVSRSSTHMVSRFLLPSILSEFTTLVISMAGDTSVRVFEQHLGSEPDVFSPCSPGQLG
                     PAPRPAAQRHLLLLGRNFAQWRRPTQQAAKAVQRFESGGDGSPGRSAPRQRLLLLEVT
                     DKKLQLLTYNWAPDLGAALGRALIRLVQWQNARAHLISCLLSQKLGLFHHCGQLDFPM
                     RDGKEPNPFLLPTMEVETLIRNASPPLSREQGRLSGSSRGGGPLSLDTFPFDEALRDI
                     TAARPSSTGGPAPRPPDPVTYHGQQFLEIKMTERKELERQMKMENLFVTWQQRSAPAS
                     MPISAGELETLKQSSRLVHYCATALLFDPAAWLHGPPETCAPSEGQRRPCPESGSGSR
                     EVPTSCESLDVPPPGAREEPWLKELSLAFLQQYVQYLQSIGFVLVPLRPPSPARSTSR
                     LRAMAILGTEGRGSFSCPKAKAEGSPKSTSTPVTTYHLQRALPGGIILMELTFQGCYF
                     CVKQFALECSRIPMGQAVNSQLSLLFTEECDKVRDLMHVHSFSYDFHLRLVHQHVLGA
                     HLALRHGYHLTTFLQHFLAHHPDGPHFGRNHIYQGTLELPTPLIAAHQLYNYVADHAS
                     SYHMKPLRMARPGGPEHNEYALVSAWHSSGSYLDSEGLRHQDDFDVSLLVCHSAAPFE
                     EQGEAERHVLRLQFFVVLTSQRELFPRLTADMRRFRKPSRLPLEPETPGSLVGSPREA
                     SGMMLAPGPAPLFPPLAAEVGMARARLAQLVRLAGGHCRRDTLWKRLFLLEPPGPDRL
                     RLGGRLALAELEELLEAVHAKSIADIDPQLDCFLSMTVSWYQSLIKVLLSRFPQSCRH
                     FQSPDLGTQYLVVLNQKFTDCFVLVFLDSHLGKTSLTVVFREPFPVQPQDSESPPAQL
                     VSTYHHLESVINTACFTLWTRLL"
     exon            102..227
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            228..401
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            402..572
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            573..704
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            705..846
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            847..953
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1164
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            1165..1335
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            1336..1570
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            1571..1700
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            1701..1843
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            1844..1996
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            1997..2111
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            2112..2326
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            2327..2542
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            2543..2621
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            2622..2716
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            2717..2885
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            2886..3000
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            3001..3114
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            3115..3285
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            3286..3380
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            3381..3504
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            3505..3669
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            3670..3874
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            3875..3990
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            3991..4237
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            4238..4379
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            4380..4472
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            4473..4551
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            4552..4845
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            4846..4987
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            4988..5095
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            5096..5159
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            5160..5345
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            5346..5513
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            5514..5601
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            5602..5673
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            5674..5875
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            5876..5975
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            5976..6105
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            6106..6258
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            6259..6361
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            6362..6467
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            6468..6579
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            6580..6698
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            6699..6863
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            6864..6948
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            6949..7113
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            7114..7281
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            7282..7415
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            7416..7582
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            7583..7680
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            7681..7813
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            7814..7944
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            7945..8045
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            8046..8222
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            8223..8490
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            8491..8570
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            8571..8696
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            8697..8896
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            8897..8987
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            8988..9068
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            9069..9143
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            9144..9357
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            9358..9511
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            9512..9634
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            9635..10040
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            10041..10157
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            10158..10226
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     exon            10227..10958
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /inference="alignment:Splign:2.1.0"
     regulatory      10938..10943
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /note="hexamer: AATATA"
     polyA_site      10955
                     /gene="Szt2"
                     /gene_synonym="6430407N22; TIGR"
                     /note="major polyA site"
ORIGIN      
        1 tacagaacta gccgggtcag aggtcaggag tggagcaacc tccctggccc gggccggcgc
       61 gggagggctg tgtgatggcc tcggagcgcc ccgagccaga ggtcgaagaa gctggacagg
      121 tgtttctgtt aatgaagaaa gattaccgaa tctcccgaaa tgttcgcctg gcttggttcc
      181 ttaatcacct gcatcaaact gttcaggcca cgccccaaga gctcctgctt cagtccgagc
      241 aggagttgga agtccttagt gttctgcccc ctggatggca gccagatgaa cccgtggtcc
      301 caaggccatt tcttcttgtg ccctccaccc gagtcacctt cctggcctgg cagtatcgtt
      361 ttgttattga gctggacctc agcccatcga ctggcattgt ggatgattct acgggggaga
      421 tcttgtttga tgaagttttc catgctctgt cccgctgtct gggtgggctg cttcggccgt
      481 ttcgagtgcc tgggtcctgt atcaacttcc agccggagat ctacgtgaca atccaggcct
      541 attcctccat cattggcctg cagtcccacc aggttctggt gcaaggctgc cttttggacc
      601 cttcccagcg ggaggcattc ctgcagcagg tatatgagca gctctgcctc tttgaggata
      661 aggtggccac catgctgcaa cagcagtatg agccccaggg ccaggcagaa gaccagtccc
      721 cagagtcagg ggagtccttg ggacggaagg taggagtctc catggtgaca gctgatcttg
      781 ggctggtcag tatgattcgt cagggcatct tggcgctgca gttactgccc tcaaattcta
      841 gtgcaggtat cattgtgatc acagacgggg tgaccagtgt ccctgatgtt gctgtgtgtg
      901 agacactact gaaccagctc cgcagtggca ctgtggcatg ctcttttgtg caggtgggag
      961 gcgtttactc ctatgattgt agctttggtc acgtgcctaa cgtggagttg atgaagttca
     1021 tcgccatggc aacgtttggc tcctacctgt ccacttgtcc tgagaccgag ccaggcaacc
     1081 tgggtctgac tgtgtaccac cgggcgttcc tgctctactc cttcctgcgc agtggggaag
     1141 ccctgaaccc tgagtactac tgtggttccc aacaccgctt gtttaacgag cacctggtct
     1201 ctgcaagcag caaccctgcc ctggccttgc gcagaaagaa gcacactgag aaggaggtgc
     1261 cagctgacct ggtcagcact gtgtctgtcc gcctccgaga gggctacagt gtcagagagg
     1321 tgactctagc caaaggaggg tcccagctgg aggtgaagct ggtgctgctg tggaaacaca
     1381 atatgcgcat tgagtatgtg gctgtggcgc cctggcccct ggagcctgag ggtcctcgag
     1441 ggaccagggt ggaagtgaca atggaaggtg gctatgacat tttacatgac gtgtcctgtg
     1501 cactacggca gcctattcgc tcgctctatc gcactcacgt tattcgccgt ttctggaaca
     1561 cactacagag cattaaccag acggatcaga tgcttgccca cctgcagtcc ttctcgtcgg
     1621 tgccggagca tttcacgctt ccagacagca cgaagagcgg agtgccgctc ttctacatcc
     1681 cacctggctc cagcaccccg gtgctctccc ttcagcacag tggctccgac tcatcccatg
     1741 cccagtttgc tgcctactgg aagccagtgc tgtccatgga cgctaactca tggcagagat
     1801 ggctgcacat gcatcgcctg gtgctaatcc tagagcatga cacgccactc cctaagcact
     1861 tgcacacccc gggcagcaat ggacgctaca gcaccatcca gtgcaggatc tcccactcct
     1921 cactcacctc tctgcttcga gactggagca gctttgtgct ggttgagggc tattcctatg
     1981 tcaagctgct ctccagtgcc ccagaccagc ccccatcctc cttctacatg gtccgcatca
     2041 tttccaagac cccttgcatg gttcttcgcc tggggtttcc aattggcaca ccagcccagg
     2101 cccggcataa gatcgtgtcg ggcttgaagg aagagatcct gcgcctccgt ttccctcatc
     2161 gggtgcaaag taaggagccg acacccaaag tgaaacggaa agggttaggg ggtgtggggg
     2221 gcagttcgcc ctccaaatcg ccccccactc tggggccaca gcaggccttg tctgaccggc
     2281 cctgcctcgt ggttcttcac aagccactgg acaagctcct catcaggtac gagaagctgc
     2341 ccctggacta cagggcaccc ttcttgctga cactggagcc accaggacca ctgcccctgg
     2401 tatcaggccg ctcggcctca tccagcctcg cctcgctgtc gcgttacctc taccatcggc
     2461 gctggctgtg gagtgtccca tcaggccttg ccccaacgct gcccctcagt gccaccgccc
     2521 agctcctctc tgtcctcact gaagtccggc tctctgaggg gttccacttc gcctgtagcg
     2581 gggaaggtat catcaacatg gtgttggagc tcccagttca gaacgaacca ctggggcagg
     2641 ctgcagctga agagaagcat acgtgtgttg tccagtacat cctctttccc ccccactcta
     2701 cctccactaa agacagcttc tcaacagatg atgacaacga tgtggaggta gaggccttag
     2761 agggggactc agagctcaat ctagtcaccg aagtgtgggt ggagcctcag tatggccgtg
     2821 tggggcctgg ccctgaaaac tggaaacacc tacaggattt gacctactct gagattcctc
     2881 aagctctcca cccacgggac gctgcctgca taggctccct gctgaccttt gagtacctga
     2941 tacagctgtg ccagagcaag gagtggggtc ctctgccccc agagccacgg ctctcagatg
     3001 ggctggacca gcgaggagac acctgtgtcc atgagatccc gttccacttt gacctactag
     3061 ggttgttgcc gcagtgccag cagctgcaga tgtttttcct cctgctttcc agagagccag
     3121 agggtgtgcc tctcgccgag gggccctgtc ccaccaacga catggtgctg tgcctgctgc
     3181 acagctgcct gggacaggag ctcagtgacc gggagatccc actgaccccc gctgaccagg
     3241 ccgccttcct gaacgaggtc ctgcggcgga gcttgcgtga cccaggtcca gaaggtcctc
     3301 cagtcggggg ccatgcagtc gctaaggatc gagcaggcaa cagcactcag gcctctggag
     3361 actccaccct tcctagccag agtgtagtga ttcctggagt tctcaggtct tccatttctg
     3421 cccagccccc tcagtggcac tgctatgcaa ggcttctggg ccctcagcac gtgttcctga
     3481 cttttctccc ggctaccttc tcagacgtcc aacatctgac tgcttacggc ctggagagtt
     3541 cctttcaaga ggaaacaaaa cccaagcttg gggattggag tggagctccg agcctgaaag
     3601 acccaggagc aacaggaact aaggctacag agtcccaagt gcccaccctc agtgtgaccc
     3661 ttgctagtga cagtgcccag gattcaggag agccaagcac accctcctgc caagacttgg
     3721 cagctaacag tggccgccag gctccccaga cagagggtgc tgacgggccc cggacccggt
     3781 gtcctgtcta catctatagc tgttccctgg aagcactgag ggaacaaatg gttggcttac
     3841 agcctccaca agcaccacgg gatctcatat tccgggctca ggacctggac cacccctcct
     3901 catcctcagc ctggatggag cccagatgca aggaggcagc cacgcactgt gccttgctgc
     3961 aggagcacgc acagcggtgc tttgtccgcg ggctgttccg aagcttgcaa caagcacaga
     4021 gcgtgacctg ccaggatctg ctgacagccg tcgatgcctg tgaggagcta ctacaagaaa
     4081 tagacatcac ctcttttctg cttgcactat gtggccatac ttggggtttg cctcatgcac
     4141 ccccaagccc tgggcctctc agtccagggc ccttcagcag tagcatcgaa gaaggaccgg
     4201 aaccccggga acgagctatc ctagtttctg agtccagtat agagaccgag gacctaagtg
     4261 agcccgagtt tcagagcagc cgtgtctctg ggaatttaga ccctggtccg gaaatttctc
     4321 tgacagatgt ctgccagctc agaggagagg cacatgatgc ccttcacagc ctcatccagg
     4381 agaagttcct ggagatcagc cgtctgcact tccgcaccgt tccctccaat ccccactact
     4441 tcttctattg cccgccatcc agtaggcgag aggatgaggg accccgagac actgtggaca
     4501 gaaaaatcag tgacctggag ttttcagaag ccgagcttgt gggcgaggaa ggggacacat
     4561 ctgcctgctg tgtggtcact gaaagcgatc cagagctgga ggtggaatac cgggagagcc
     4621 gagaaccaga cctggggccc gctgggctag actccgcatc actgtcagat gcagacactg
     4681 tgaaccccga tgaggactcc ttcagtatct tagggggcga ctcccccact gggccagaca
     4741 gcctcatgca tgacctgcca cctctcttct tacacctcac atgctccgtg cggttgcgcg
     4801 gacagcacag ctcggtgcct gtgtgcagcc tgcccacctg cctgggtcaa gtgctttcca
     4861 gtctagaggg acccccgatt ggaggccgag tcccactgag ggacctcagt atcactcttg
     4921 atgtctttgt gttgacctta cccctggaag tggaactacc tccagcctcg gaccctcaac
     4981 accaccggtc aacatccgag agcagtgctt cattcccacg gtccccggga cagccctcgt
     5041 ctttaaggtc agatgatggc ctaggacccc cactgccgcc cccagaagaa gagaggcacc
     5101 caggactgtc cagtttggcc atgccccata gactggctat tgagagcaca atgaacgaga
     5161 tccgctggct gttagaagac gagatggtag gggcactccg gagagggggc atcccccaga
     5221 gccctgccct gcaccgagcg gctgcccaca ttcatagctc ttctggacgc cctacctgcc
     5281 tccgccaagc tccccctctg agttttgtgt ttgggccaga gcgctccctc acacagttca
     5341 aggaggagtt ccggcgcctt cacctccctg gccacgttct cctcgaggac cctgacagtg
     5401 gcttcttctt tgtggcagct ggccaacaac caggtgtact ccatggggaa cccccttcag
     5461 cagcctgggc ttggcacaac catgaagaca gggctgaaga tgctgaaggg gaggtcctga
     5521 cagccagccc ccaagtccct ggctcgctag aggattctga aggcaccccc ctcattagcc
     5581 ttcccagcct ttcacaggga ggaagtcagc ctgggcctag tcggggacta agcctcatgt
     5641 ccagtcaagg cagtgtggac tcagaccacc ttgggtatga cggtggcagc agtggctcag
     5701 acagtgaggg tcccggtgag actcttggtg agaaagccct cttcacgctg cggactccac
     5761 ctggaccagc acctccacag ccttcactcc ctgtccttcc tgggccctcc ctgcctgact
     5821 tctggctcat cgtcaggata ctgcaggacc gtgtggaagt gtatgcacat gcacggagcc
     5881 tgagtcgtga ggatggcggc ccgggtgctg agtgtcgcca cctgcagcaa ttcctggtga
     5941 ggcgtgttgg ggaaatctgc agagaggtca accagcgact gctccttcaa gaccttcacg
     6001 acagtcatgt gtgtaactcc cttctggtgg ccgagagtga agaagatctg tggcgcagcg
     6061 agacgccttt ccattcccgt cagcgggcag tcctgcccag tgatgatttc gctgctgacg
     6121 agagctgtgc tcctcgagga tacctagccg ccaccatgca gtttgtccca ggacatttct
     6181 cctgtgacgt tgtatgggga actgtgatcc gagtccattc acggctcaag atgggaccca
     6241 gcatgggggt ctctcgggct atccaggccc tgcgctctgt gctcaatgcc ttctctgtgg
     6301 tgaaccggaa gaatatgttt gtttatcaag agcgagcaac aaaggccgtg tactaccttc
     6361 ggctgctgga gacttcttgc agtgaccgac cgtgggaagg ggataccctg cccccatccc
     6421 tagctctatc ccgaagccaa gaacccattt cctctgagga ttccgtggct cctcgttctc
     6481 cactggacat ggcttccagc cgcagttcag atgctgtgcg ccctgtgggc caagtggaca
     6541 gacatatcca gctgctggtc catggcgtag gacaggcagg tcctgaaatc acagatgagt
     6601 tagtgcgggt tctgcgccgg cggctggacg aggccaccct ggacatcatc acagtcatgc
     6661 tggttcggaa ttgcaagctg accccggccg acgtagagtt catccaacct cctgggagtc
     6721 tcccctcaga ggtgctgcat ctggtcttgc ctccgtcctg cagaccctgc cttcctgccc
     6781 tggcctggta cctccgccag aacttactca ccttcctgca ctcccccaag tacacagaca
     6841 gcaatagccg gaaccacttc caacatccac tcccagcaca gggtggcctc cccgacttgg
     6901 acatctactt gtataataaa cctggtggac agggcactgg tggcaaaggg gttgcctgca
     6961 tcactctagc ctttgtggaa gaaggaggaa cccccatctc actggcatca tggcccccct
     7021 cttctccggg gcccccagac ccactacgag aagaagaatt tgagcagctg actcaggtca
     7081 ttcgctgccc aaacacattg gacagttgtt cagctcagga tggatcccca cggcttcgac
     7141 tggacgtgtg ggaaaagggg aacattagca tagtacaact ggaggagaag ctccgggctg
     7201 ctgctcgcca ggccctggcc gacgccatca tggagctgcg gctgctgcca gcctcactgt
     7261 gtacagaaga catccctcca ggaagtctta agagcggacc attggatacc aagagccctg
     7321 cctgccgagc caacaccttt ccctgtaccc ctgtctccgg ggagcctgtg actccaccta
     7381 gcaaagctgg ccgccgcagc ttctgggata tgctgagtaa aacagaagct ggagatttgg
     7441 gttcccccaa aacaactgat gatattgtcc tggatcggcc agaagatact cggggtcgga
     7501 gacgtcataa aaccgagaat gttcggaccc caggtggatc tgagcgggca ccgggcccag
     7561 attctggagc ccagagacaa agacgccgga caacacagct agaggagggt gaggtgggga
     7621 ccctgcatcc cgtatttgct cgtgtcattc agcgctggat gggattcatg gttcagattg
     7681 gttgtgcctc agtgtccagg agctccaccc acatggtatc ccggttcctc cttccatcca
     7741 tcctgtcaga gttcaccact ctggtcatct caatggctgg agacaccagt gtccgtgtct
     7801 ttgagcagca tttaggttct gagccagatg tcttcagccc ttgttctcca gggcagctgg
     7861 gcccggcccc ccgcccagca gctcagcggc accttcttct tctgggaagg aacttcgccc
     7921 agtggaggag accaacccag caggctgcca aagctgtgca gcgctttgag tcaggaggag
     7981 acggaagccc agggagaagc gctccccggc aaaggctttt gctgctagag gttacagata
     8041 agaagctaca gctgctgact tataactggg ctccagacct gggtgcagca ttgggccgag
     8101 ctctgatccg ccttgtccag tggcagaatg cgcgagccca cctcatctcc tgcctgctca
     8161 gccagaagct cggtctcttc caccactgtg gccagttaga ctttcccatg cgtgatggaa
     8221 aggagccaaa cccattcctg ctgccgacca tggaagtgga gaccctcatc cggaatgcaa
     8281 gccctccact gagtcgcgaa cagggccggc tgagtggctc ctctcgtggg ggaggtcccc
     8341 tttccttgga cacatttccc tttgatgaag ctctgaggga catcacagct gctcgcccga
     8401 gctctacagg tggtcctgcg cccagacctc cagatcctgt gacctaccac gggcagcagt
     8461 tcttagaaat taagatgaca gaacgaaaag agctggagcg ccagatgaag atggagaacc
     8521 tgtttgtaac ctggcagcag cgttctgcac cagcgagcat gcccatcagt gctggggagc
     8581 tggagaccct gaagcagtca tcccgcttgg tgcattactg cgcgactgct ctgctctttg
     8641 acccagctgc ctggctgcac ggacccccag agacttgtgc accctctgaa gggcagcgac
     8701 gaccgtgccc tgagtcaggg tctggaagcc gagaggttcc cacaagctgt gaatccttgg
     8761 atgtgcctcc tccaggagcc cgagaggagc catggctgaa ggagctgagc ttggccttcc
     8821 tgcagcaata cgtgcagtat ctgcagagca ttggctttgt gctggtgcca ctccggcccc
     8881 cctcacctgc ccgcagtacc agccggctac gggctatggc tatccttgga acagagggtc
     8941 gaggctcctt ctcctgcccc aaagccaagg ctgaggggag cccaaagagc accagtactc
     9001 cggtcaccac ctaccacctg cagcgggcac tgcctggggg catcatcctc atggagctga
     9061 ccttccaggg ctgttacttc tgtgtcaaac agtttgctct ggaatgttcc cgaatcccaa
     9121 tgggacaagc cgtcaactct cagctgtccc tgctgttcac agaggaatgt gacaaggtcc
     9181 gtgatctgat gcatgtgcac tccttcagct atgacttcca cctgcgcctc gtgcaccagc
     9241 acgtgctcgg tgcccacctg gcactgcggc acggctacca cctcaccacc ttcctgcagc
     9301 acttcctggc ccaccaccct gatggacccc actttggccg taatcacatt taccaaggga
     9361 cgctggagct ccccacccca ctcattgctg cccaccagct gtacaactat gtggctgacc
     9421 atgccagttc ttaccacatg aaaccactgc gaatggcccg gcccggtggt ccggaacata
     9481 atgaatatgc cctggtgtca gcatggcata gctctggctc ctatctggac tcggaagggc
     9541 ttcggcatca ggatgacttt gatgtgtctc tgcttgtctg tcactctgct gcacccttcg
     9601 aggagcaagg agaggctgag cgacatgtgc tgaggcttca gttctttgtg gtgctaacca
     9661 gccaacgaga acttttccca agactcactg ctgacatgcg cagattccgg aaaccctcca
     9721 ggcttcccct tgagccagag actcctggga gcttggttgg tagccccagg gaagcctcag
     9781 ggatgatgct ggccccaggg ccagctcctc tgttcccacc attggctgca gaagtgggta
     9841 tggcccgggc acggctagct cagctggtta ggttggctgg tgggcactgc cggcgggata
     9901 ccctctggaa gcgcctattc ttgctggagc caccagggcc tgaccggcta aggcttggag
     9961 ggcgcctggc cctggcagag ctggaggagc tcttagaggc agtccacgcc aagtccattg
    10021 cggacattga cccccagctg gactgtttcc tctccatgac ggtctcctgg taccagagcc
    10081 tcatcaaggt tctcctgagc cgattccccc agagctgccg ccattttcag agcccagact
    10141 tgggaaccca gtacctggtt gtgctgaatc agaagttcac cgactgcttt gtcttggtgt
    10201 ttctggactc acacctggga aagacgtctc tgacggtggt tttccgagag cccttcccgg
    10261 tgcagcccca ggacagtgag agccctcctg cccagctggt ctctacctac caccacttgg
    10321 agtctgtcat caacacagcc tgtttcaccc tctggacccg ccttctctga gaagtggacc
    10381 agtgactctg ttgattgaat catggatcta taagcttgcc cgcttgaggc aggacagact
    10441 ggcacttagg aaccccaggg taaactcaga cacagaatga cactaaagga ctgagtatgt
    10501 ctgggagaag tgctgctaca gcctggcaac aggaacatag ctgctgaaca gcccggactc
    10561 gcctcaggcc cctgggcctg tgcagaagag gatgcctcct tcctgcacac ctggtggagt
    10621 gccagggaat gtcacatgat ctgacaagct ctcacctcta agagctctgc cacttggcca
    10681 tcactgttgg acattaccat tgagatagac ttggttccga tcttgactcg gcctgtcaag
    10741 cacctgtgac cagtcttacc tcctcccgtc cccactggac ctttggttcc tcatctgtgg
    10801 ataaggaggg ctcagaagtc tcctgtgtcc acagcaaccc tggaggattt gagcttgagc
    10861 tgtgtgtccc ttctcagtgg gagggaatta acctggagac attgaagcat tagacactat
    10921 gtgtccccca cccctgtaat atacacatat gagaacgc
//
