LOCUS       NM_030725               3758 bp    mRNA    linear   ROD 19-NOV-2024
DEFINITION  Mus musculus synaptotagmin XIII (Syt13), mRNA.
ACCESSION   NM_030725
VERSION     NM_030725.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3758)
  AUTHORS   Pulcrano,S., De Gregorio,R., De Sanctis,C., Volpicelli,F.,
            Piscitelli,R.M., Speranza,L., Perrone-Capano,C., di Porzio,U.,
            Caiazzo,M., Martini,A., Giacomet,C., Medina,D., Awatramani,R.,
            Viggiano,D., Federici,M., Mercuri,N.B., Guatteo,E. and
            Bellenchi,G.C.
  TITLE     miR-218 Promotes Dopaminergic Differentiation and Controls Neuron
            Excitability and Neurotransmitter Release through the Regulation of
            a Synaptic-Related Genes Network
  JOURNAL   J Neurosci 43 (48), 8104-8125 (2023)
   PUBMED   37816598
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3758)
  AUTHORS   Bakhti,M., Bastidas-Ponce,A., Tritschler,S., Czarnecki,O.,
            Tarquis-Medina,M., Nedvedova,E., Jaki,J., Willmann,S.J.,
            Scheibner,K., Cota,P., Salinno,C., Boldt,K., Horn,N., Ueffing,M.,
            Burtscher,I., Theis,F.J., Coskun,U. and Lickert,H.
  TITLE     Synaptotagmin-13 orchestrates pancreatic endocrine cell egression
            and islet morphogenesis
  JOURNAL   Nat Commun 13 (1), 4540 (2022)
   PUBMED   35927244
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3758)
  AUTHORS   Tarquis-Medina,M., Scheibner,K., Gonzalez-Garcia,I.,
            Bastidas-Ponce,A., Sterr,M., Jaki,J., Schirge,S.,
            Garcia-Caceres,C., Lickert,H. and Bakhti,M.
  TITLE     Synaptotagmin-13 Is a Neuroendocrine Marker in Brain, Intestine and
            Pancreas
  JOURNAL   Int J Mol Sci 22 (22), 12526 (2021)
   PUBMED   34830411
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3758)
  AUTHORS   Loo,L., Simon,J.M., Xing,L., McCoy,E.S., Niehaus,J.K., Guo,J.,
            Anton,E.S. and Zylka,M.J.
  TITLE     Single-cell transcriptomic analysis of mouse neocortical
            development
  JOURNAL   Nat Commun 10 (1), 134 (2019)
   PUBMED   30635555
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3758)
  AUTHORS   Quintana-Urzainqui,I., Kozic,Z., Mitra,S., Tian,T., Manuel,M.,
            Mason,J.O. and Price,D.J.
  TITLE     Tissue-Specific Actions of Pax6 on Proliferation and
            Differentiation Balance in Developing Forebrain Are Foxg1 Dependent
  JOURNAL   iScience 10, 171-191 (2018)
   PUBMED   30529950
REFERENCE   6  (bases 1 to 3758)
  AUTHORS   Krawchuk,D. and Kania,A.
  TITLE     Identification of genes controlled by LMX1B in the developing mouse
            limb bud
  JOURNAL   Dev Dyn 237 (4), 1183-1192 (2008)
   PUBMED   18351676
REFERENCE   7  (bases 1 to 3758)
  AUTHORS   Petri,A., Ahnfelt-Ronne,J., Frederiksen,K.S., Edwards,D.G.,
            Madsen,D., Serup,P., Fleckner,J. and Heller,R.S.
  TITLE     The effect of neurogenin3 deficiency on pancreatic gene expression
            in embryonic mice
  JOURNAL   J Mol Endocrinol 37 (2), 301-316 (2006)
   PUBMED   17032746
REFERENCE   8  (bases 1 to 3758)
  AUTHORS   Mu,X., Beremand,P.D., Zhao,S., Pershad,R., Sun,H., Scarpa,A.,
            Liang,S., Thomas,T.L. and Klein,W.H.
  TITLE     Discrete gene sets depend on POU domain transcription factor
            Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic
            retina
  JOURNAL   Development 131 (6), 1197-1210 (2004)
   PUBMED   14973295
REFERENCE   9  (bases 1 to 3758)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   10 (bases 1 to 3758)
  AUTHORS   Fukuda,M. and Mikoshiba,K.
  TITLE     Characterization of KIAA1427 protein as an atypical synaptotagmin
            (Syt XIII)
  JOURNAL   Biochem J 354 (Pt 2), 249-257 (2001)
   PUBMED   11171101
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL844903.11 and AL713913.10.
            
            On Oct 27, 2022 this sequence version replaced NM_030725.4.
            
            Sequence Note:.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK082425.1, AK083803.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-269               AL844903.11        102986-103254
            270-495             AL713913.10        6787-7012
            496-630             AL713913.10        9086-9220
            631-932             AL713913.10        11948-12249
            933-1062            AL713913.10        17336-17465
            1063-3758           AL713913.10        19397-22092
FEATURES             Location/Qualifiers
     source          1..3758
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 51.37 cM"
     gene            1..3758
                     /gene="Syt13"
                     /gene_synonym="5730409J20Rik; mKIAA1427"
                     /note="synaptotagmin XIII"
                     /db_xref="GeneID:80976"
                     /db_xref="MGI:MGI:1933945"
     exon            1..269
                     /gene="Syt13"
                     /gene_synonym="5730409J20Rik; mKIAA1427"
                     /inference="alignment:Splign:2.1.0"
     exon            270..495
                     /gene="Syt13"
                     /gene_synonym="5730409J20Rik; mKIAA1427"
                     /inference="alignment:Splign:2.1.0"
     exon            496..630
                     /gene="Syt13"
                     /gene_synonym="5730409J20Rik; mKIAA1427"
                     /inference="alignment:Splign:2.1.0"
     exon            631..932
                     /gene="Syt13"
                     /gene_synonym="5730409J20Rik; mKIAA1427"
                     /inference="alignment:Splign:2.1.0"
     exon            933..1062
                     /gene="Syt13"
                     /gene_synonym="5730409J20Rik; mKIAA1427"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..3758
                     /gene="Syt13"
                     /gene_synonym="5730409J20Rik; mKIAA1427"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3533..3538
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Syt13"
                     /gene_synonym="5730409J20Rik; mKIAA1427"
                     /note="hexamer: AATAAA"
     polyA_site      3552
                     /gene="Syt13"
                     /gene_synonym="5730409J20Rik; mKIAA1427"
                     /note="major polyA site"
     regulatory      3638..3643
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Syt13"
                     /gene_synonym="5730409J20Rik; mKIAA1427"
                     /note="hexamer: ACTAAA"
     polyA_site      3661
                     /gene="Syt13"
                     /gene_synonym="5730409J20Rik; mKIAA1427"
     regulatory      3734..3739
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Syt13"
                     /gene_synonym="5730409J20Rik; mKIAA1427"
                     /note="hexamer: ATTAAA"
     polyA_site      3758
                     /gene="Syt13"
                     /gene_synonym="5730409J20Rik; mKIAA1427"
ORIGIN      
        1 ggagtctaga gagcggctgg agccaggcgg gagcgcgagg tgcaggaggc cggcgggagg
       61 cgggcgagcc gcgggaagca ggcaccatgg tgctgtcggt gcctgtgatc gcgctgggcg
      121 ccacgctggg cactgccacc agcatccttg cgctgtgcgg ggtcacttgc ctgtgccgac
      181 acatgcaccc caagaagggg ttgctgccgc gggaccgtga gcccgacccg gagaaggcaa
      241 ggcccggtgt gcttcaggcg gcccaacagt tcaacattaa aaagtccacg gagcctgtcc
      301 agccccgacc tctccttaag ttcccggaca tctatggtcc ccggccagcc gtgacggccc
      361 cagaagtcat caactacgca gactacacct tggagaccac agaggagtct gctgcacctg
      421 ccagccccca ggcccagagt gacagtcgcc tcaagaggca ggtcacagag gagctgtcca
      481 tccgtcctca gaacggtgta gttgaggatg tctgtgtcat ggagacctgg aacccagaga
      541 aggctgccag ctggaaccag gcccccaaac tccacttccg cctggactat gaccagaaga
      601 aggctgagtt atttgtgaca agcctggaag ctgtcaccag tgaccatgaa ggaggctgtg
      661 actgttacat ccaaggcagc gtggctgtca agaccggctc tgtggaggca cagacagctc
      721 tgaagaagcg gcagctgcac acaacctggg aggagggcct ggccctgccc ctgggtgagg
      781 aagagctccc cacagctacc ctgacactca ccctgcgcac ctgtgaccgc ttctcccgcc
      841 atagtgtgat tggggaactc cgcctgggcc tggatggagc atctgtaccc ctgggggcag
      901 cacagtgggg tgagctgaag accacagcaa aggagccatc tgcaggggcc ggggaggtcc
      961 ttctgtcaat cagctacctc ccagctgcca atcgcctcct ggtggtgctg attaaagcta
     1021 agaacctcca ctccaaccaa tccaaggagc tgctgggcaa ggatgtgtct gtcaaggtga
     1081 ccttgaaaca ccaggctcag aagctgaaga agaaacagac aaaacgggcc aagcacaaga
     1141 tcaaccccgt gtggaacgag atgatcatgt ttgagctacc ggatgacttg ctgcgggcat
     1201 ccagtgtgga gctggaggtg ctgggccagg gcgaggaggg gccgagctgc gagctgggcc
     1261 actgcagcct aggcctgcat gcctcgggct ctgagcgcag ccactgggag gagatgctaa
     1321 aaaacccacg ccggcagatc gccatgtggc accaactgca cctgtagtcg gccacctgcc
     1381 accggccact gaccgtcttt cttggacaca gtcatcttcc aggctcagct gtcagtcatc
     1441 cctcgtgctc tgtccacatg cctataccca aagacagatg cagacgtgtt ggctgaggcc
     1501 aagacctcat tcctctctta ctgtattccc aatactaaaa agtgagcggt ggcgccagga
     1561 cagtgagtgg gactggcact cagaagactg tatcatgctc atctgtgtta tggaaaaaga
     1621 tatgtgccag gtaccctcag tcggcagccc ctgctcacat tgagctgaag cagtggttct
     1681 taacctgtgt atcacaaccc tctatctcca aaaaatattt acattatgat tcataacagt
     1741 agcaaaatta cagttacaaa gtagcaatga gaacaattct gtggttggag atcaccaaaa
     1801 cacaagaaac tttcttatag ggtcacagca ctaggaaggt tgagaatcac tggctggcca
     1861 gcaggtctct gggccactgg ggggtcatgc cacactgatg ttccggtgga atacacaagc
     1921 ctctgtcctt agctagcaca ggggttctgg agcagagcag gaggggctgc gcttgataag
     1981 atcccttctc ccctatccag gcagcctttc ctcttgatct ccgggggccc agcaccagga
     2041 cagtgtgaag gcaggaactc tctgcttact ttatttcttc ttttttatat ttctgctgtt
     2101 catattccac tctcgagcta cattgtgtgt tttgactgtt ttatttaagg gattggagtg
     2161 ggttgtgttt gttttttttt tatcacacgt agagtgcccg ttccctggca ggcctaggtt
     2221 gccactcctc tggagtgtct gcggcattct gaggacagct gtcatgtcac ccccccccac
     2281 ccccaagctg actccatgtg acagacctgt tcttctcagt atgcctgtac ttcaggacga
     2341 agtagctctg agcttggctt gttccatctg gctatgtaaa tgaggaggta gatgaacttt
     2401 aaagagaaaa cgtggtctct tgataacatg cctccctcca gtttggggga catgtccttt
     2461 aacttggaaa taacaaaaag ctaggtttga ttgcccctgt tgatatttcc aatagatgcc
     2521 ccactaggaa tcaaataagt agctagctgc aggggtagat acttgtgagc cggaattcga
     2581 gttgtcatta cttccttgct ccacagcgcc tcagtgtggc cacctatagc acagcaccaa
     2641 tgtcatggga gcttgccagt ccagcttcag gaggtaagca agaggcatct tagcgggcat
     2701 caattgttac tggtcagttg gtggcacttc ctggctcctc cgttggctgt gcttcttctc
     2761 caaaacctcc tctgtaaatt gctcagagat gttagactgg gaaccaaaaa ctttcagtca
     2821 ccttttacat cggcttaatc tgtttccagc cattcctgta agtcacctcc gaatcagctt
     2881 gggaaggaac ctctctatgt ctttgccagg gagtgatttc tggaaagagg tggaaataaa
     2941 gtgagaggcc attccaggct gggctactgc tgggaggtta ggagttcacc ccagtcctct
     3001 gtgaatcctc tccccaggac aactaggcat ctatttgttg agtgtttgtc caccaagacc
     3061 gtgcatgtgt ctgtccattc tgattagaga aggctctggg ggcgagtgag tagcttatca
     3121 ccttaacgga aacatcagat aagaggagtc cgggactgct gttcaggcgg gcagctctca
     3181 gatgtaaagg ggccccgggg gaaggggcag tgtctggcct gaactgaggt gggaatcttt
     3241 ggaggagaaa gttggtcctg tgcagtgttt ctacccttgc tgtttcctgt tgttagatgc
     3301 tgcgtgtttg tgatgccatt ccacataaaa gcacaaaaag tcgcatgaga catcgtggtc
     3361 acatgtctgg ttacactttg gagcacaaaa tcttacagtg gtaaataaat cgttttccaa
     3421 tcgggttggc agcccagtgt ttctctttgt tcctttacat taatatttta gatgtataaa
     3481 attcagaaaa aaaatctcgt gtatcaaaca cccatgaacc tctgccaact tcaataaacc
     3541 ttgacgacca cagttgaatt ttcttcttgt gccctatact gagaagacca ggatcttaca
     3601 ttctgatttg ttattctgag ccttccttta tatttttact aaatgatcat ttgatccctg
     3661 agcactagtg agtatttgtg tgtttccaag ttttacttca attcttaaat tgcatcacac
     3721 attttttttc aacattaaaa atttaagctt tatgcaga
//
