LOCUS       NM_025575               1602 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus SYS1 Golgi-localized integral membrane protein homolog
            (S. cerevisiae) (Sys1), mRNA.
ACCESSION   NM_025575
VERSION     NM_025575.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1602)
  AUTHORS   Tan,G.H., Liu,Y.Y., Wang,L., Li,K., Zhang,Z.Q., Li,H.F., Yang,Z.F.,
            Li,Y., Li,D., Wu,M.Y., Yu,C.L., Long,J.J., Chen,R.C., Li,L.X.,
            Yin,L.P., Liu,J.W., Cheng,X.W., Shen,Q., Shu,Y.S., Sakimura,K.,
            Liao,L.J., Wu,Z.Y. and Xiong,Z.Q.
  TITLE     PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by
            regulating synaptic transmission in cerebellum
  JOURNAL   Cell Res 28 (1), 90-110 (2018)
   PUBMED   29056747
REFERENCE   2  (bases 1 to 1602)
  AUTHORS   Liu,X., Jiao,Y., Cao,Y., Deng,N., Ma,Y., Hasty,K.A., Kang,A.,
            Chen,H., Stuart,J.M. and Gu,W.
  TITLE     Decreased expression levels of Ifi genes is associated to the
            increased resistance to spontaneous arthritis disease in mice
            deficiency of IL-1RA
  JOURNAL   BMC Immunol 17 (1), 25 (2016)
   PUBMED   27480124
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1602)
  AUTHORS   Diament,A.L., Farahani,P., Chiu,S., Fisler,J. and Warden,C.H.
  TITLE     A novel mouse Chromosome 2 congenic strain with obesity phenotypes
  JOURNAL   Mamm Genome 15 (6), 452-459 (2004)
   PUBMED   15181537
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591478.19.
            
            On Jan 12, 2022 this sequence version replaced NM_025575.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK013220.1, AK003071.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-142               AL591478.19        14050-14191
            143-379             AL591478.19        14364-14600
            380-447             AL591478.19        16372-16439
            448-1602            AL591478.19        17429-18583
FEATURES             Location/Qualifiers
     source          1..1602
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 85.16 cM"
     gene            1..1602
                     /gene="Sys1"
                     /gene_synonym="2610042O14Rik"
                     /note="SYS1 Golgi-localized integral membrane protein
                     homolog (S. cerevisiae)"
                     /db_xref="GeneID:66460"
                     /db_xref="MGI:MGI:1913710"
     exon            1..142
                     /gene="Sys1"
                     /gene_synonym="2610042O14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            143..379
                     /gene="Sys1"
                     /gene_synonym="2610042O14Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             218..688
                     /gene="Sys1"
                     /gene_synonym="2610042O14Rik"
                     /note="Sys1 homolog"
                     /codon_start=1
                     /product="protein SYS1 homolog"
                     /protein_id="NP_079851.2"
                     /db_xref="CCDS:CCDS50793.1"
                     /db_xref="GeneID:66460"
                     /db_xref="MGI:MGI:1913710"
                     /translation="MAGQFRSYVWDPLLILSQIVLMQTVYYGSLGLWLALVDALVRSS
                     PSLDQMFDAEILGFSTPPGRLSMMSFVLNALTCALGLLYFIRRGKQCLDFTVTVHFFH
                     LLGCWLYSSRFPSALTWWLVQAVCIALMAVIGEYLCMRTELKEIPLSSAPKSNV"
     exon            380..447
                     /gene="Sys1"
                     /gene_synonym="2610042O14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            448..1602
                     /gene="Sys1"
                     /gene_synonym="2610042O14Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      989..994
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sys1"
                     /gene_synonym="2610042O14Rik"
                     /note="hexamer: AAGAAA"
     regulatory      1022..1027
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sys1"
                     /gene_synonym="2610042O14Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1027
                     /gene="Sys1"
                     /gene_synonym="2610042O14Rik"
                     /note="major polyA site"
     polyA_site      1057
                     /gene="Sys1"
                     /gene_synonym="2610042O14Rik"
                     /note="major polyA site"
     polyA_site      1435
                     /gene="Sys1"
                     /gene_synonym="2610042O14Rik"
                     /note="major polyA site"
     regulatory      1584..1589
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sys1"
                     /gene_synonym="2610042O14Rik"
                     /note="hexamer: AATACA"
     polyA_site      1602
                     /gene="Sys1"
                     /gene_synonym="2610042O14Rik"
ORIGIN      
        1 aggaagccgt gggccgcagc tattcggcct ctctaggccg gcgggtcctc cgctccatgg
       61 tcctgtctgt cagcgctgtg tcaggaggcc agtgccgagg tccggtcgcg ctccgacgct
      121 tcgaccctcg agccggtcgc gggtatcccg gcggccgcgg gacgatggcg tggtggcact
      181 gacaggcgcg ggcggctgcc gagccccgcg ggccggcatg gcgggccagt tccgcagcta
      241 cgtgtgggac ccgttgctaa tcctgtcgca gatcgtactc atgcagaccg tctactatgg
      301 ctctctgggc ctgtggctgg cgctggtgga cgcgctggtg cgcagcagcc cgtccctgga
      361 ccagatgttc gacgcggaga tcctgggctt ctccacccct ccaggccggc tctcaatgat
      421 gtccttcgtc ctcaacgccc tcacctgtgc cctgggcttg ctgtacttca tccggcgagg
      481 gaagcagtgc ctggatttca ctgtcactgt gcatttcttt cacctcctgg gctgctggct
      541 ctacagctcc cgtttcccct cggcgctgac ctggtggctg gtccaggctg tgtgcattgc
      601 actcatggcc gtcatcgggg agtacctgtg catgcggacg gagctcaagg agatccccct
      661 cagctcagcc cctaagtcca atgtctagag ttgggccctt tggacactct gctggcactt
      721 gggccccatc accttgggct gctcagacct ccagatgggg tctggcccaa gtctgagcag
      781 aaccctggaa atgtgaagtc tgttggtgga gagataatga ggtcccatca taaaggcagg
      841 tagcagccat gatcacagat gtaagaatgg cctctgtctg ccaaagcctt gatatctgga
      901 ggccagtaag ggacctcatg gagggtagtg gcagatttgg aaccatgtca catgagccat
      961 catactgtca ccagcctgtt attttaaaaa gaaaaaaaaa aaatcaagga tatctgattg
     1021 gaataaacca ctcttctcgt tgtctgtctt atgcccatga cagccagtac ctttgctgtg
     1081 ttgccaaacc acagggattc tctgtggaga aatacctgat ttctgggtcc atagccacag
     1141 aaaaagatgt aggtacagag tgctaggctg ctgacaggac gtcgagggga ggaggcatca
     1201 agcacaagaa aaatgcatgg ccgtgccgtt agacacacac acacactttt gtgtgtgtcc
     1261 aggacccatg actgtctccc tccagttccc tgtatggact ctgccttgct gttgtcactc
     1321 agcacagcca gagacaggac ccagagaaaa ccccagcatc cctcccagcc ttcccttcat
     1381 aataaaagcc attgtctgct ctctggaagt gagcaggcag ccagcttcta ctggacctca
     1441 actgtggcag gagtttctgt ttgctgtctt ttgagttctg tgatagggag ggtgtactaa
     1501 aggtgctgga ggctcaccct gctaagcttt cttccaagtg gtttcctcag gaagggctgg
     1561 cagctgtcct tcctaggtac ataaatacac tattttccaa tc
//
