LOCUS       NM_177340               5012 bp    mRNA    linear   ROD 31-DEC-2024
DEFINITION  Mus musculus synaptopodin (Synpo), transcript variant A, mRNA.
ACCESSION   NM_177340 XM_001479956 XM_001479958 XM_981156
VERSION     NM_177340.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5012)
  AUTHORS   Siegerist,F., Kliewe,F., Hammer,E., Schakau,P., Chi Soh,J.E.,
            Weber,C., Lindenmeyer,M., Reichelt-Wurm,S., Drenic,V.,
            Chatziantoniou,C., Chadjichristos,C.E., Zhang,Y., Simm,S.,
            Banas,M.C., Nauck,M., Volker,U. and Endlich,N.
  TITLE     The role of the tricellular junction protein ILDR2 in
            glomerulopathies: Expression patterns and functional insights
  JOURNAL   iScience 27 (12), 111329 (2024)
   PUBMED   39640577
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5012)
  AUTHORS   Inglebert,Y., Wu,P.Y., Tourbina-Kolomiets,J., Dang,C.L. and
            McKinney,R.A.
  TITLE     Synaptopodin is required for long-term depression at Schaffer
            collateral-CA1 synapses
  JOURNAL   Mol Brain 17 (1), 17 (2024)
   PUBMED   38566234
  REMARK    GeneRIF: Synaptopodin is required for long-term depression at
            Schaffer collateral-CA1 synapses.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5012)
  AUTHORS   Kruse,P., Brandes,G., Hemeling,H., Huang,Z., Wrede,C.,
            Hegermann,J., Vlachos,A. and Lenz,M.
  TITLE     Synaptopodin Regulates Denervation-Induced Plasticity at
            Hippocampal Mossy Fiber Synapses
  JOURNAL   Cells 13 (2), 114 (2024)
   PUBMED   38247806
  REMARK    GeneRIF: Synaptopodin Regulates Denervation-Induced Plasticity at
            Hippocampal Mossy Fiber Synapses.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5012)
  AUTHORS   Langner,E., Cheng,T., Kefaloyianni,E., Gluck,C., Wang,B. and
            Mahjoub,M.R.
  TITLE     Cep120 is essential for kidney stromal progenitor cell growth and
            differentiation
  JOURNAL   EMBO Rep 25 (1), 428-454 (2024)
   PUBMED   38177914
REFERENCE   5  (bases 1 to 5012)
  AUTHORS   Hu,H.T., Lin,Y.J., Wang,U.T., Lee,S.P., Liou,Y.H., Chen,B.C. and
            Hsueh,Y.P.
  TITLE     Autism-related KLHL17 and SYNPO act in concert to control
            activity-dependent dendritic spine enlargement and the spine
            apparatus
  JOURNAL   PLoS Biol 21 (8), e3002274 (2023)
   PUBMED   37651441
  REMARK    GeneRIF: Autism-related KLHL17 and SYNPO act in concert to control
            activity-dependent dendritic spine enlargement and the spine
            apparatus.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5012)
  AUTHORS   Kostka,G., Giltay,R., Bloch,W., Addicks,K., Timpl,R., Fassler,R.
            and Chu,M.L.
  TITLE     Perinatal lethality and endothelial cell abnormalities in several
            vessel compartments of fibulin-1-deficient mice
  JOURNAL   Mol Cell Biol 21 (20), 7025-7034 (2001)
   PUBMED   11564885
REFERENCE   7  (bases 1 to 5012)
  AUTHORS   Hammes,A., Guo,J.K., Lutsch,G., Leheste,J.R., Landrock,D.,
            Ziegler,U., Gubler,M.C. and Schedl,A.
  TITLE     Two splice variants of the Wilms' tumor 1 gene have distinct
            functions during sex determination and nephron formation
  JOURNAL   Cell 106 (3), 319-329 (2001)
   PUBMED   11509181
REFERENCE   8  (bases 1 to 5012)
  AUTHORS   Doyonnas,R., Kershaw,D.B., Duhme,C., Merkens,H., Chelliah,S.,
            Graf,T. and McNagny,K.M.
  TITLE     Anuria, omphalocele, and perinatal lethality in mice lacking the
            CD34-related protein podocalyxin
  JOURNAL   J Exp Med 194 (1), 13-27 (2001)
   PUBMED   11435469
REFERENCE   9  (bases 1 to 5012)
  AUTHORS   Moore,A.W., McInnes,L., Kreidberg,J., Hastie,N.D. and Schedl,A.
  TITLE     YAC complementation shows a requirement for Wt1 in the development
            of epicardium, adrenal gland and throughout nephrogenesis
  JOURNAL   Development 126 (9), 1845-1857 (1999)
   PUBMED   10101119
REFERENCE   10 (bases 1 to 5012)
  AUTHORS   Mundel,P., Heid,H.W., Mundel,T.M., Kruger,M., Reiser,J. and Kriz,W.
  TITLE     Synaptopodin: an actin-associated protein in telencephalic
            dendrites and renal podocytes
  JOURNAL   J Cell Biol 139 (1), 193-204 (1997)
   PUBMED   9314539
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY128958.1, AK158933.1 and BC065127.1.
            
            On or before Oct 19, 2007 this sequence version replaced
            XM_981156.1, XM_001479956.1, XM_001479958.1, NM_177340.1.
            
            Transcript Variant: This variant (A) represents the longer
            transcript and encodes the longer isoform (A).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK154958.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-337               BY128958.1         1-337
            338-2513            AK158933.1         361-2536
            2514-5012           BC065127.1         2660-5158
FEATURES             Location/Qualifiers
     source          1..5012
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 34.36 cM"
     gene            1..5012
                     /gene="Synpo"
                     /gene_synonym="9030217H17Rik; 9130229N11; 9330140I15Rik"
                     /note="synaptopodin"
                     /db_xref="GeneID:104027"
                     /db_xref="MGI:MGI:1099446"
     exon            1..135
                     /gene="Synpo"
                     /gene_synonym="9030217H17Rik; 9130229N11; 9330140I15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            136..2513
                     /gene="Synpo"
                     /gene_synonym="9030217H17Rik; 9130229N11; 9330140I15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2514..5012
                     /gene="Synpo"
                     /gene_synonym="9030217H17Rik; 9130229N11; 9330140I15Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttgcttaggg cgctgagtgg gcgccgccgc tgggcggggt gcagggatct cggggcgggg
       61 ctcacgcacg gacgtagcca ggtgagccaa ggcggcggcg cccgggagct cggggaccgc
      121 gcacggctgc tggagcactg ggccggagca caagcttcac cgaaaacgac ctgaaggagg
      181 ccaaggcgag gagccagcag attgcagccc agctgaccac ccctcccagc tccaattccc
      241 gaggggtcca gctcttcaac aggcgcaggc agagggtgaa cgagttcacc ttggagagcc
      301 gaggccagag gtcaccaaag ctcaaccaag aggccctcca aacagggcgt cctttgagcc
      361 ccataggcca tgccccgggg cctagtgtga agcccacatc tccatcaaag ccaggctctc
      421 caaagcaccc cagtccccaa agccccagcc gaggggtcgc tggccacatc atggaggggt
      481 actcagagga agccagtctg ctgcggcatc tggagaaggt tgccagtgag gaagaggaag
      541 tgccattggt agtttattta aaggagaatg cagccctgct gacagccaat gggctacacc
      601 tgtcgcagag ccgagagacc cagcagtcct caccaaaccc tcccgacact gaagtaccca
      661 gtccagctgc agatatcaac cagaacccgt cctcacctaa tgccacactc accacactag
      721 cctctagcag tcaccacagt cagcccaccg ctgatatcaa ccaaaaccct ccagccgcca
      781 tcacccctgt cccacagaat tcatcccagg cacagtgctc cccgaatggc acacttgatt
      841 ccaaacccgg cactctgtgt gctgatgatg ggcagtcccc ggtgccggca gaggaggtga
      901 gatccagcat tctcttgatt gacaaggtgt cagctccacc ttctgccgcc agcaccttct
      961 ctagagaagc cacgcccctc tccagctctg ggccgccagc ggcagatctc atgtccagct
     1021 ccctgctcat tgacatgcag cctagcaccc tagtggcacc agcagaacaa gaggtgcctg
     1081 gccatgtagc tgtcaccacg cccactaagg tgtatagtga agtacatctc acactagcca
     1141 agcctgcatc cgtggtcaac aggaccgcca ggccttttgg gatccagtcg ccagggacca
     1201 gccagataga gcaaagcccc atgatgggaa gacgacagtt tggagagaag gcctgggctc
     1261 ctcctgctag cagtatggcg gataggagtc cccagccaca gaggcacata atgtcccgca
     1321 gtcccatggt ggaaaggaga ctgcttgggc agcgaagccc ggtcctagag agacgcccct
     1381 taggaaattt caccccaccc cccacctatg cggagacttt gtcaacagcc cctgtggctt
     1441 ctcgggttag gtctcccccc tcttactcca ctctgtatcc cagctctgac cccaagcctt
     1501 cccatttgaa aggtcaggta gcccctgcca acaagacagg aattttggaa gaatctatgg
     1561 cacgccgagg cagccggaaa tcaatgttca ctttcgtgga gaagcccaag gtgaccccga
     1621 atccagattt gctggaccta gtgcagacag ctgatgagaa gcggaggcag agagaccacg
     1681 gggaggtggg catggaagaa gagccctttg ccctgggagc tgaggcctcc aacttccagc
     1741 aggagccaat agctcgggac agggccagcc ctgcggcagc tgaggaagct gtccctgagt
     1801 gggcctcttg cctcaagtca ccccgtatcc aggccaagcc gaagcccaaa cccaatcaga
     1861 acctctcgga agcctcaggg aagggggctg agctctatgc ccgccgccag tcacggatgg
     1921 agaaatacgt catagagtct tcaggccatg ccgaattggc ccgctgccct tcacctacca
     1981 tgtccctgcc ttcatcctgg aagtacacca ctaacgcccc tgggggcttc cgagtggcat
     2041 ccttaagtcc agcgcggacc ccgcctgcct ctctctacca cggctatctg ccagagaatg
     2101 gagtcctgcg ccctgaacct accaagcagc agccatacca gatgcggcct tccctctatg
     2161 ctctgtcgcc cgtcaaggaa cctgccaagg cctcatcgcg tgccacctca tcgcgcactc
     2221 catcacgcac tgtctcacct cgagctgcct ccccggccaa gcctagctct ctggacctgg
     2281 tgcccaacct gcccagagca ggcctcccac catctcctgc tctgcctcgg ccttcccgct
     2341 cctccccagg cctctacact gccccagtcc aagacagcct ccagcccact gccgtgagtc
     2401 ccacttacag cagtgatatc tcccccgtgt ctccctccag ggcgtggtct cctcgagcca
     2461 agcaggctcc caggccttcc ttctccaccc ggaatgctgg gatcgaggcc caggaccgcc
     2521 cggagagcct gcccacgtcc ccgccctgga cgccggccgc ttcccggcct cctagcagcc
     2581 tggacggctg ggtgagcccg gggccgtggg agccgggccg cgggagcagc atgagcagcc
     2641 ctccgccgct gccgccgcct ccaccaatgt ccccctcgtg gagcgagcgc tccgtctccc
     2701 cgctgcgatc ggagaccgag gcgcggcccc cgagccgcca gctgcaggcg cttctggcgc
     2761 gcaacatcat caacgcggcc cggcgcaaga gcgcctcccc gcggccagcg ccggctgaga
     2821 ccctgcggcc cttttccccg ccgcaggggc cgccgccgcc gccggcgcgc atgcgctctc
     2881 cgcagccagc cagccctgcc cgtaacttcc gtggagctgc tttctctccc atcccgcgga
     2941 gcccgttgcc catcggacct tcttcctgtg ctagtccccg gagtcctcaa gccgcgccgt
     3001 ccaggccttt tccctaccgc cgctcaccca cagactccga cgtgtctctc gactccgagg
     3061 attctgggct taagtcgcct ggcatcctcg gctacaacat ctgtcctcgg ggctggaatg
     3121 gcagcctgag gctcaagcgt ggtagtctcc ccaccgaggc ctcctgcacc acctaaagtt
     3181 tcatctctgc cccgggaggg tcgagccgga agaggcacta agcttggggg aaccccagca
     3241 ccgagatccg aagggtctga cctcattgga cagctctaga gaaaaaaggg gtcagggaag
     3301 gagagctctg ggcttggggg gcctgtccat caaacttggg ttgtagccct tggttttgcc
     3361 atttatttgt atggctctga ggaagagcct cttgtctttg acccttagct ttggccaatg
     3421 cagtctccag acatcttccc tttccttcca ttcacgtgtg ccttagggga ggcagctaag
     3481 cacacagcca tcgaccttca tcattgccag gcttccatgc ttcttcctcc aacactgctt
     3541 tctacagcct ggcaaatgaa gtatgtgttg aaaagaacct tggccatgac ctgggcccgg
     3601 gccctggctt gaccgtcgct cctggcatca agtcccaggc gggagcagct gttttccatc
     3661 tcttcgcaga ctagctctat ttttatctgg tgacctttaa agagatctcc caggcaagct
     3721 caaggtgccc tgctgggccc ctctggggag aaggggctgg aagattctct ccaggcactg
     3781 ccatgctgct ttctctatcc cccccagctc agggtgtcta gactatccct atggccaggg
     3841 cagagcagag agtaaagttc cctggggcta tgggtctcag gagccccaga ctcctgtttt
     3901 tctgggctta ttgatggcta gttttaggtt tttcaaaacc ggggagagac gagaaggcag
     3961 tctagggtgt gttacctatt tggaaagggg ttcttgttgc agaatatgca aaccatggcc
     4021 aggatacgta gacaagactt aagtattggg tggagctgac tcttgacctc tgaggattct
     4081 tgaaattcac tccatagtat cagaaatcga ggggttaagg gggagcttca cagggctcga
     4141 attccgatgc aaataaacct gggtgggaag tcaagtatgc cagtatgggc ttgccatagt
     4201 gtctatagta tgcccagaag ggtgggcatt gttatattca ttttcttcac atctcactgt
     4261 ggcctggatc atgcctatac ccagtggcct taaggtgcct ctccccttaa tctcagtgac
     4321 tctgattcca gtccccaaga gtgactgggg gaagaagagc tgagttttgt gtgtttcata
     4381 gtcaacaggt gatatccctt gaaggttcag agtatcatct tcagaattca gagcctgggg
     4441 ctgggggtgc tggagttaga tgaggcacaa atatatgacg gtgggggaaa atactaggat
     4501 gttgttaaag gtaagggatg atgcgatttt ggagtgatta gtagatttgc ccacatatca
     4561 gggttatcta gagctcctga gtaaggttag gggaagctag ggtcaggatg gaataaagtc
     4621 agggttggaa tggagtgcat cggaatagag gggtgatctt ggtaggttcc tattgcccat
     4681 gggtttgaga accaggccct gggaagatga gagagtactc agctcctacc tggtgcagca
     4741 tcccttgtag ttacagagtc ccaagctagg gaagcctccc agagaagaga ccctactaga
     4801 attctagctc atgctttggc atacatagat cagcttctac ctgcaattcc tgggataacc
     4861 aggagggggc agctttgaga agctacagtt ctgttcccgc agttgtcata gtgactgcct
     4921 tctcacttag ctggtctcta aaacccacca cagcttgcct gtatcctgcc ttgtgcctct
     4981 tgtagaattc agagcaataa atgcgttctg ca
//
