LOCUS       NM_025292              10417 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Mus musculus synaptojanin 2 binding protein (Synj2bp), transcript
            variant 1, mRNA.
ACCESSION   NM_025292
VERSION     NM_025292.7
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 10417)
  AUTHORS   Janer,A., Morris,J.L., Krols,M., Antonicka,H., Aaltonen,M.J.,
            Lin,Z.Y., Anand,H., Gingras,A.C., Prudent,J. and Shoubridge,E.A.
  TITLE     ESYT1 tethers the ER to mitochondria and is required for
            mitochondrial lipid and calcium homeostasis
  JOURNAL   Life Sci Alliance 7 (1), e202302335 (2023)
   PUBMED   37931956
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10417)
  AUTHORS   Ilacqua,N., Anastasia,I., Aloshyn,D., Ghandehari-Alavijeh,R.,
            Peluso,E.A., Brearley-Sholto,M.C., Pellegrini,L.V., Raimondi,A., de
            Aguiar Vallim,T.Q. and Pellegrini,L.
  TITLE     Expression of Synj2bp in mouse liver regulates the extent of
            wrappER-mitochondria contact to maintain hepatic lipid homeostasis
  JOURNAL   Biol Direct 17 (1), 37 (2022)
   PUBMED   36457006
  REMARK    GeneRIF: Expression of Synj2bp in mouse liver regulates the extent
            of wrappER-mitochondria contact to maintain hepatic lipid
            homeostasis.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 10417)
  AUTHORS   Beauchamp,M.C., Boucher,A., Dong,Y., Aber,R. and
            Jerome-Majewska,L.A.
  TITLE     Craniofacial Defects in Embryos with Homozygous Deletion of Eftud2
            in Their Neural Crest Cells Are Not Rescued by Trp53 Deletion
  JOURNAL   Int J Mol Sci 23 (16), 9033 (2022)
   PUBMED   36012294
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 10417)
  AUTHORS   Adam,M.G., Berger,C., Feldner,A., Yang,W.J., Wustehube-Lausch,J.,
            Herberich,S.E., Pinder,M., Gesierich,S., Hammes,H.P., Augustin,H.G.
            and Fischer,A.
  TITLE     Synaptojanin-2 binding protein stabilizes the Notch ligands DLL1
            and DLL4 and inhibits sprouting angiogenesis
  JOURNAL   Circ Res 113 (11), 1206-1218 (2013)
   PUBMED   24025447
REFERENCE   5  (bases 1 to 10417)
  AUTHORS   Yagita,Y., Hiromasa,T. and Fujiki,Y.
  TITLE     Tail-anchored PEX26 targets peroxisomes via a PEX19-dependent and
            TRC40-independent class I pathway
  JOURNAL   J Cell Biol 200 (5), 651-666 (2013)
   PUBMED   23460677
REFERENCE   6  (bases 1 to 10417)
  AUTHORS   Liu,Z.H., Tsuchida,K., Matsuzaki,T., Bao,Y.L., Kurisaki,A. and
            Sugino,H.
  TITLE     Characterization of isoforms of activin receptor-interacting
            protein 2 that augment activin signaling
  JOURNAL   J Endocrinol 189 (2), 409-421 (2006)
   PUBMED   16648306
REFERENCE   7  (bases 1 to 10417)
  AUTHORS   Tsuchida,K., Nakatani,M., Matsuzaki,T., Yamakawa,N., Liu,Z.,
            Bao,Y., Arai,K.Y., Murakami,T., Takehara,Y., Kurisaki,A. and
            Sugino,H.
  TITLE     Novel factors in regulation of activin signaling
  JOURNAL   Mol Cell Endocrinol 225 (1-2), 1-8 (2004)
   PUBMED   15451561
  REMARK    GeneRIF: Overexpression of ARIP2 enhances endocytosis of ActRIIAs;
            data indicate that ARIP2 is a novel factor regulating cell surface
            ActRIIA expression and activin function.
REFERENCE   8  (bases 1 to 10417)
  AUTHORS   Matsuzaki,T., Hanai,S., Kishi,H., Liu,Z., Bao,Y., Kikuchi,A.,
            Tsuchida,K. and Sugino,H.
  TITLE     Regulation of endocytosis of activin type II receptors by a novel
            PDZ protein through Ral/Ral-binding protein 1-dependent pathway
  JOURNAL   J Biol Chem 277 (21), 19008-19018 (2002)
   PUBMED   11882656
REFERENCE   9  (bases 1 to 10417)
  AUTHORS   Gotthardt,M., Trommsdorff,M., Nevitt,M.F., Shelton,J.,
            Richardson,J.A., Stockinger,W., Nimpf,J. and Herz,J.
  TITLE     Interactions of the low density lipoprotein receptor gene family
            with cytosolic adaptor and scaffold proteins suggest diverse
            biological functions in cellular communication and signal
            transduction
  JOURNAL   J Biol Chem 275 (33), 25616-25624 (2000)
   PUBMED   10827173
REFERENCE   10 (bases 1 to 10417)
  AUTHORS   Nemoto,Y. and De Camilli,P.
  TITLE     Recruitment of an alternatively spliced form of synaptojanin 2 to
            mitochondria by the interaction with the PDZ domain of a
            mitochondrial outer membrane protein
  JOURNAL   EMBO J 18 (11), 2991-3006 (1999)
   PUBMED   10357812
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY745220.1, AK163362.1, AC154908.4, AC132391.3 and AI851233.1.
            
            On Jun 13, 2015 this sequence version replaced NM_025292.6.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer protein (isoform 1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK033514.1, AY138960.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-38                BY745220.1         1-38
            39-1090             AK163362.1         3-1054
            1091-7320           AC154908.4         49028-55257         c
            7321-10401          AC132391.3         1-3081
            10402-10417         AI851233.1         1-16                c
FEATURES             Location/Qualifiers
     source          1..10417
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 37.73 cM"
     gene            1..10417
                     /gene="Synj2bp"
                     /gene_synonym="ActRIP4; ARIP2; D12Wsu118e; OMP25"
                     /note="synaptojanin 2 binding protein"
                     /db_xref="GeneID:24071"
                     /db_xref="MGI:MGI:1344347"
     exon            1..196
                     /gene="Synj2bp"
                     /gene_synonym="ActRIP4; ARIP2; D12Wsu118e; OMP25"
                     /inference="alignment:Splign:2.1.0"
     CDS             133..570
                     /gene="Synj2bp"
                     /gene_synonym="ActRIP4; ARIP2; D12Wsu118e; OMP25"
                     /note="isoform 1 is encoded by transcript variant 1;
                     activin receptor interacting protein 2; activin
                     receptor-interacting protein 4; outer membrane protein 25;
                     mitochondrial outer membrane protein 25"
                     /codon_start=1
                     /product="synaptojanin-2-binding protein isoform 1"
                     /protein_id="NP_079568.1"
                     /db_xref="CCDS:CCDS26021.1"
                     /db_xref="GeneID:24071"
                     /db_xref="MGI:MGI:1344347"
                     /translation="MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIYV
                     SRIKEDGAAAQDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGCAVSLRVQHRLPV
                     QNGPIVHRGEGEPSGVPVAMVLLPVFALTMVAVWAFVRYRKQL"
     exon            197..333
                     /gene="Synj2bp"
                     /gene_synonym="ActRIP4; ARIP2; D12Wsu118e; OMP25"
                     /inference="alignment:Splign:2.1.0"
     exon            334..429
                     /gene="Synj2bp"
                     /gene_synonym="ActRIP4; ARIP2; D12Wsu118e; OMP25"
                     /inference="alignment:Splign:2.1.0"
     exon            430..10402
                     /gene="Synj2bp"
                     /gene_synonym="ActRIP4; ARIP2; D12Wsu118e; OMP25"
                     /inference="alignment:Splign:2.1.0"
     regulatory      829..834
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Synj2bp"
                     /gene_synonym="ActRIP4; ARIP2; D12Wsu118e; OMP25"
                     /note="hexamer: AATAAA"
     polyA_site      853
                     /gene="Synj2bp"
                     /gene_synonym="ActRIP4; ARIP2; D12Wsu118e; OMP25"
                     /note="major polyA site"
     regulatory      10377..10382
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Synj2bp"
                     /gene_synonym="ActRIP4; ARIP2; D12Wsu118e; OMP25"
                     /note="hexamer: AATAAA"
     polyA_site      10397
                     /gene="Synj2bp"
                     /gene_synonym="ActRIP4; ARIP2; D12Wsu118e; OMP25"
ORIGIN      
        1 ggtttccttt tccggtctga ccgctgagga aactgtaaaa gctatgctgg ggaggcagcg
       61 cggagcttga ttcaccttca cctgctctgg ccacccgctg acccggggtt tccggccgga
      121 gagcagtcag atatgaacgg acgggtggat tatttagtca cggaggaaga gatcaacctg
      181 acgagaggac cttcggggct gggcttcaac atcgtcggtg ggacagatca acagtatgtc
      241 tccaacgaca gtggcatcta cgtcagccgt atcaaagagg atggggctgc ggcccaggat
      301 gggcggctcc aggagggtga taagatcctc tcggtaaatg gccaagatct gaagaacctg
      361 ctgcaccaag atgctgtaga cctcttccgt aatgcgggat gtgctgtgtc cctgagagta
      421 cagcacaggt taccagtgca gaatggacct atagtacatc gaggtgaagg agagccaagt
      481 ggagttcctg tagctatggt gctgctacca gtgtttgccc tcaccatggt agcagtttgg
      541 gccttcgtga gataccgaaa gcagctttga aatgcttgct gtcttccagt gtgtccaatg
      601 aactctctct ctcactcacc atctctgaca tcctcccata ttctttctcc tccacatagc
      661 caatacaaga tttaaagtga ctgcttatca cccaaaaccc tgctattcaa aatctcctat
      721 tctaatggaa gagtacaggg gttatttgaa gaaaagctgt ggtggtgtgt gtgtggggga
      781 agccttgctt agaatgaatg agaagttaca tattttacta ggactgccaa taaaaactca
      841 gctatcatcc aaagaggaaa agctcagcct tcctgtctcc atggacgaca cctttctctt
      901 agctggcatg ctgtgatggc tagctgtgct atgtgaaagg aggagctgat tttgtttttt
      961 tttttttttt taaatgcttt ttcttgggaa gtatttgtgg cctttaattt gtaactatat
     1021 acctagatgc ctatattgga cataggcgaa tgaagttttt tctttctttc gtttttattt
     1081 tttttaaatt aaaaaagaaa atatatgtat acagtaatac acacacacac acacacacac
     1141 agtagcataa aattgatgcc ttatggagaa ttaaagaggt aagaaagcta ctggttcttg
     1201 ggtttctaat ggacaatttt gggggactag gggatcatat tccctcatat ataatcaaga
     1261 ctcatattga aaaatgagtt ctggattgta aagagaactt actttttcca cttgcctgta
     1321 agtctttgtc cacaagttaa aaacatacac agtgctaagg aatgatcata actgaaacat
     1381 ttcaagaact attagcagag catgtatatt gaggatgggg aagttagctt taaaagagaa
     1441 tgctcagtca gtgacattag gaaaataatg actgaagcaa ttagttaaaa attgtagagc
     1501 aactggtgtt actcagtagc tacagtgctg tgggaaattg tagtaaggca tctctactca
     1561 agtcaatttg ttcaaaaggc tttgggatat acagatgagt cccacagtct ctgaactgcc
     1621 ttagttgcta ttttacagta ctgttaaagg atccattggc atgggatggg aagcagcagg
     1681 gcccaatcaa ccatcaagac atctgaaaaa gatcatgtct caaggtggca cttgagcctt
     1741 caaaactgct taacaattct cagtttctag tgtcagacaa aaagcctaag ggaaggaact
     1801 gccctcctgg taggatggac ctgaatcagc ctgcttctga ctgagttagg atgagaaggc
     1861 attggtatgg gttttctttt tgaaaaaaaa aaaaaaaaaa agtatttttt gaaaaaggta
     1921 ttttccccca aagctataaa cactagtttt ggttttaata aggttaatgg accatttttc
     1981 aaaaaggaga aggaataagt tttgtttgtt tgtagagggt gcaaggaaat ttggtgagca
     2041 tttctgagga aagcctgagt acacagtgta atgaagagat gctggagatg cagggatatt
     2101 ggtgaggtgg gagctgtcct gtttatgtaa catctaagtt ggttttagag tactgaggat
     2161 agttgaacca agcctatttt ttttccactt taacaaaata atttccttct tttcagtaaa
     2221 ttggccagac tattattttg acataagatt atgaagagtt ttcccgacag tctagcagtc
     2281 acttaacaga tgttgattgc acattagttt tgtcaggaca cctttataaa aagagaaatg
     2341 cacatatttc atccaaaggg acattgtggt tacagttagg aaggaaaccc ttaaaatgga
     2401 gttagttatc taagtgtaag ttgtttatat tacagacagc aaaagaaaat agctcctgag
     2461 gtctggacac tgaggatttc atagaagagg gaatcgttag gtgccaatca tctagtaaga
     2521 gcatgcataa atagaggaaa agttaagaat cttatcaggg tgagtaataa acacaaccag
     2581 taagaaaaat attgccatcc aaaacagagc acagtgcagc aacatagaag ataagcagat
     2641 aaccagcaag tattgtaagg agttcagaaa aggaaagcca tcgtgtagtg gcatcagggg
     2701 agaatggaaa ggaaagtcta gaacagtcca gtgatacttt acctctggga aaactcttga
     2761 tacagggaga catttgcttt aaacaatctt cacataacta agccattcag tactttttga
     2821 aactgactta gtaacaggag tcattgtaag ctccatagaa ggcaagacgc attccacatc
     2881 ttgtcttgac cagcagcact ctggaggccc agtgtctgct acccttcttg tatctgatgg
     2941 catgggtaac agctctgcca tgggcctgct tacttctagt attcacctca gggcttggaa
     3001 attggttttg aaaggctttt agacatagaa agtaaaacta atggcaagga ggataaaaca
     3061 ctgttgtgtg ttgtattgtt gatctaaata aaaaatatca ttggtagaag ttttactttg
     3121 gttgataagg attctgataa catttgggtc tccttaggaa agaaacactt aactaaaaca
     3181 tttaagtttt aggcaaatac tgtaatattt cactcttagt tatatgaaaa ctaaatgaga
     3241 tgttgagaat ctatatagat tattcaaatt ttatgtttct tatagactga ctcaaatatt
     3301 cctaccacct taaaattata tatgatgcac ctaccacata aattataatg tttaatgttt
     3361 tgaaaatgga ttataggtat ttttaagttt tcataaagta tttcttatat ttgtcattgt
     3421 gaattatatg taattctaat agacactgtt tgcttcagtt gtttttgttt ccttttccta
     3481 cagttttctg tgtgggtgat ttcatttaat taattggaca gtctagccac aggcaacaaa
     3541 tagaaatagt atttgtaatt atagtctatg ccagggactg tcttaaactg attagtaaca
     3601 ctatgactta ccctgagatc taagtattgc tataaagaga ctgaagagga gagaataaag
     3661 tattttccta ggactacata gttggtaaaa gagaatcatg atttaaactc tggactatgg
     3721 atggcagtat cagtaatatt ccctcatagc tagcagtcct catgcaaggt ctctgaacaa
     3781 aagcaacgta tcacctgcaa atgcttgggt ttcatcccat tcttatggag tgagatgagt
     3841 gtgtgccagc cagcaactct gtccttctag gtaactggtt catgctgaac cttgagattc
     3901 accactgtca ggagctctct ctctctgctt agaatcatcc agacagcggg ctggtcagcc
     3961 cacattaaat aagaacatgt gggactagaa ttcagtcaac aatgacatgt ttcatcaggt
     4021 ggttaaaatg tacagattct gttggaaatg ttccatggta tttcaatagc cagaatgaag
     4081 aactgggcta agtccagagc tctgctctct gagcatctgc cccagataca gaggcagagt
     4141 atgaagtgga acattgtttt attcctaggt gctcaggaca gactgatcaa cctccagtaa
     4201 catatgtggt tagtaagtgc ttcagcttgt gtagccatta ataaccaagt cataggattg
     4261 tgaatctaaa atactcctgg gtaaaatttg tattagaatg gaaaaaaaaa tgagggtcag
     4321 aaaggtgagc taacttcaag ttagatactc ccctctattt tggtctcaaa tttgttttag
     4381 tgtgtccaca acatgaaaac atacaaaaac tatattttaa aaatcagttt actttcatct
     4441 tttctcttta ggctttcaat aaagaccaga aggactgata gacagctaga gaggatcgtg
     4501 taggcatcca gattagaatg gaagaatcca ttgaacaatc tgagaaaact aatcaggtgt
     4561 tgttttaatc acattagttt taagttagat acatgctctt tgtagtattt tgggttttat
     4621 tgtgcaaata agcaattaaa atatatttag aagccaagta taatggtaca tgtctttgct
     4681 ctcagcatta ggatgcagag gcaagcagat ctctgtgagt aggaagctag tgttagatct
     4741 ccctcaccct ctcctccctc tccctctccc tctccctctc cctctccctc tccctctccc
     4801 tctccctctc cctctccctc tccctctccc tctccctctc cctctccctc tccctcttcc
     4861 ttcctccctt cctcttcttc ttccctgcct ccctctctcc ctcttcctct ggtgtgtgtg
     4921 tgtgtatgtg tgtgtgtgta gtcataagga ttttatttta cccactttga gtggaatgta
     4981 tctttgtaca gataatgatg tttttcttca tttagcagat aactatcaac actagtacag
     5041 aaatacaaag ataaaattta gtcactaagc tggaacaact taccttttga gagtgggtga
     5101 tctttttttg tatcttttta acatcactga agaatacagg gtttgacttc ctaagctctc
     5161 tacctctcac agtagtttca gggttggcta ctatcctagg ttaagtgtgc acgctcgact
     5221 tgcccagaaa gcatatgcca caacaggatc cttctgcaca cgtttattgg gagagcttga
     5281 ttgcagaggc gaaaagaccc agagcccaga actggtgctg cttatatagg cctaggagag
     5341 gcgtgtctca cacccgattg gttatgcttt cagtacctca tttacatatc tacatccgat
     5401 tggttatgct ctcagtacct cgttaacata ccccatttac atatctacac ccgattggtc
     5461 atgcattcag tacctcattt acatgtcccg ggccaggcag tgactaggca aaaaaactct
     5521 actgcacatg cgcatattgg ttgtttaccc aaacttatgg gtggtggcca gcggtagtaa
     5581 gcgccacctt gtaatggcat atatggcttc ccacagttaa gccttctttg ctgtaccttt
     5641 taacttcaaa attttattga gaccagtcct cacctacagt gtgcagttat gatttttaaa
     5701 aaagagacag tattttaaag aattctgacc agtgggaatg agattctgaa ctgccattaa
     5761 ctcttgtgtt gatatgtata tagagagttc aaagcatgtg actatttacc cgatgcactt
     5821 aataatacaa aatttgacag aagaaagcac tgttgatgaa aaatccagct ctattaaaca
     5881 ctaatgcctc taactgcgaa ttcccctcat gttccattac tataggggag acagggaaga
     5941 aaggaggact aataaaggtt ttcaatgcaa ttttgttatt tgccagcaga atgatttaca
     6001 aaagaacttc gtaatatatt gactagtaac aggaaactgg gatgattctt ttcagtgttg
     6061 acaggtttgc aaatgaagac acagaattga atttcgtttc agttgtaatg ctatgtttct
     6121 aattctgttt gaatacgagt ttattattac tggatacttg tataccttcc aggcttttca
     6181 cttcttggaa aattattttc tttaagtacc ttatgttatt tcctttctgc tctgattctt
     6241 tttttttctt tcagttttta aaatctactt agaatattaa acaggatgga agtagaaaaa
     6301 aactcatatg aagtcctcta tgaaaggaaa ttgtgacaag ttcctgattg gacagaaacc
     6361 attccatctc caagggagaa tatgcagtgt aactgtgtct tcatagaatg agttagatag
     6421 tgttccttct gtttctattt tgtggaatag tttgaagagt ataggtattt tgtcttcttt
     6481 aaaggtctga cagaatggga ctctttagat agtatatctg atatttggta tctgtctaga
     6541 aaattgttca tctatatttt ccagttttgt tgaatatagg cttttgtagt aggatctgat
     6601 gcttttttaa tttcctcagt ttctgttgtt atatctgcct tttcatttct gattttgtta
     6661 atttggacac tgtctttgtg ccctctggtt agtctggcta agggtttatc tgtcttgttg
     6721 attttctcaa agaaccacct cctggtttgg ttgattcttt gtatagttct ttttgtttct
     6781 acttggttga tttcagccct gtgtttgatt atttcctgcc atctactcct cttgggggta
     6841 cttctttttg ttctagagct tttaggtctg ctgttaagct ggtagggttt gctctctcca
     6901 gttttttttt tttttgtttt gttttttttt ttttttttgg aggcactcag agccatgagt
     6961 tttcctctta ggactgcttt cattgtgtcc cataagtttg ggtatgttgt actgtcattt
     7021 tcattaaatt ctaaaaagtc tttaatttct ttctttattt cttccttgac caagttatca
     7081 ttgagtagag tgttgttcag cttccatgtg tatgtgggct ttctgttgtt tttcttgcta
     7141 ttgaagacta gccttaatcc gtagtgatct gataggcatg ggattatttc agtctttttg
     7201 tatctgctga ggtctgtttt gtgactgatt atatggtcaa ttttggagaa ggtaccatga
     7261 gatgctgaga agaaggtata ttcttttgct ttaggatgaa atgttctata gatatctgtt
     7321 gaattcataa cttctgttct tttcactctg tctctgtttt gtttgtgttt ccctgatctg
     7381 tccgatgatg aaagaggggt gttgaagtcc cccactatta ttgttcgcgc tgcattaacg
     7441 tttgttttat gaatgtgtgt gcccttgtat ttggagcata gatgttcaga attgagagtt
     7501 cttcttggta gatttttttc ctttgataag tatgaagtgt ccttccttat cttttttgat
     7561 gacttttggt tgaaatttga ttttattcaa tattagaatg gctactccag cttgtttctt
     7621 gggaccattt gtttggaaaa ttgttttcca tccctttact ctaaggtagt gtttgtcttt
     7681 gacactcagg tgtgtttcct gtatatagta aaatgttggg tcccgtttac gcaaccagtc
     7741 tgttagtcta tgtcttttta ttggggaatt gggtccattg gtgttaagag atattaggga
     7801 atagtgattg ttgcttcctg ttatttttat gtgtgtgtgt atcttctttt gggtttgttg
     7861 aatgaagatt actttcttgc tttttttagg gtgtagtatt cctccttgtg ttgggagttt
     7921 tccatctatt attattcttt atagggctgg atttgtggaa tgatactgtt taaatttggt
     7981 tttgtcatgt aatatcttgg tttctccatc tatggtaatt gagaggtttg ttgggtatag
     8041 tagcctgggc tggcatttgt gttctcttag ggtctgaatg acatctgtcc agggtcttcc
     8101 agctttcata gcctcttgtg agaagtcagg tataattctg ataggtcagc ctttatatgt
     8161 tacttgacct tttctccttg ttgcttttaa tattcttttt ctttgttttg tgcatttgat
     8221 gttttgacta ttatgtgacg ggaggaattt tttttctggt ccagtctatt tggaggcttg
     8281 taagcttctt gtatgttcat gggcatctct ttgtttaggt taggaaagtt ttcttctata
     8341 attttgttga agatatttac tgacccttta agttgagaat cttcactctc ttctaaacct
     8401 attatccttg atttggtctt attgtgtcct ggatttcctg gatgttttgg gttaggatct
     8461 ttttgcattt cgcattttct ttgactgttg tgccaatgtt ttctatggta tcttctgcac
     8521 ctgagattct ctcttttatc tcttgtattc tgttggtgat gcttgcatct gtgactcctg
     8581 atctctctcc tgggttttct atctccaaga ttgtctccct ttgtgatttc tttgtttttt
     8641 ctatttcaat ttttagatcc tgtgtgagca ctaaaagggg tgtaggggaa ggagggggaa
     8701 gggcagataa cctgcgccca gccagagttc ctcttatgct ccaggcaggc ggatacggga
     8761 ggggtactgg gcactgtcca ctcggccctg ggtgggcatc taagccactg accccactca
     8821 atggtggggg gagggcggac aaggggcagc ccccaaccgg ggaccccagg gcgacaccgg
     8881 gttgccctgg ggttattgga gagaggcgag agtaaacaca gtgggccttg atgaacagag
     8941 acagtctatg gttttagagc tttattgtag aaaggcaggg agaaagagaa aaggtagaaa
     9001 gagaaagaga ctggccatgt ccgagaggag agaaaggggg aaaaggagag agagaagaaa
     9061 ggctagagta agagggagag agcaagaggg aaagggtgag gagagagcaa ggagagagta
     9121 aggggagtaa gagcaagaga gtaaggaggg gccaaacagc ccctcttatg gtgtgctgtt
     9181 atctttactg ttgctagcta gcctgaaagt cagaagcttg ggacattgcc tatgtgacta
     9241 ctaaccatgc ttctcttgtg ggagctgagg gggcagtaac tttgacagga gccagggttc
     9301 caggagacat gagagaactc cttccatccc atgtaagtga attatcacca ctgggtcccg
     9361 ggattcaaca tctagcctca actggaaacc aggctgtctg tacatagccc agagccccac
     9421 aatcctggat gattttgttc aattccttca cctgatttgt tgtgtttttc tgtaattctt
     9481 taagggattt ttgtgttacc tctttaaggg tttctagctg ttaacctgtg ctcccctgta
     9541 tttctttaag ggagttattt atgtccttct taaagtcctc tatcatcatc atgacatatg
     9601 attttaaatc agagtcttga ttttctggtg tgtcgggcta tccagggttc gatagaactg
     9661 aattctgaag gtagaactgg attctgataa tgctaagtag tcttgttttc tattacttat
     9721 gttcttgctc tcacctctcg ccatctgttt atctctggtc ttagctcatc ttgctgtctc
     9781 taactgtgac ttgtctctcc tataaacctg tgtgtcagca ttcctgggag accagttctc
     9841 tcctagagga atttgggtct ggaaagctgt ggcacagggt caattctggg tgcagacgga
     9901 aaccagaagg atcctttcct tggctgttcc ttagttcctg tatcttgatg gctttgggct
     9961 cgtccctctt ggtccaggaa tttgagtaga agtggtggtc ctacctgtgc tcactgattt
    10021 gtcagcactc ctgggagacc agctctctcc cagcggtatt ttggtatgga gcgctgtgac
    10081 acaggatcag cttctggtac agatggaaac tcgaagaatc ctgtcccagg ttgctcctag
    10141 gctcctctgt cctgatggct ctgtgtgagt ctctttctgc tctaattctt atatcccttg
    10201 gatccctgta tgtaaacatc agctgtttca caggttgcat gcctgagagc tacttgcaaa
    10261 gcaagtagac ataaatcaca ttaactagga ctcatcacca attcatcagt gatcctgttt
    10321 caagatcact gtttgatacc agtgtgtcca gatttgcctc ttgaactatg acactcaata
    10381 aagacctgtt taacttattg aaaaaaaaaa aaaaaaa
//
