LOCUS       NM_025819               3668 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus SWT1 RNA endoribonuclease homolog (S. cerevisiae)
            (Swt1), mRNA.
ACCESSION   NM_025819
VERSION     NM_025819.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3668)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3668)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   3  (bases 1 to 3668)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY062718.1, AK004803.2, CV563132.1 and AC165946.4.
            
            On May 7, 2009 this sequence version replaced NM_025819.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK004803.2, SRR7345562.2468958.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-72                BY062718.1         1-72
            73-1895             AK004803.2         20-1842
            1896-2090           CV563132.1         240-434
            2091-2989           AK004803.2         2038-2936
            2990-2991           AC165946.4         38354-38355         c
            2992-3668           AK004803.2         2939-3615
FEATURES             Location/Qualifiers
     source          1..3668
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 64.08 cM"
     gene            1..3668
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /note="SWT1 RNA endoribonuclease homolog (S. cerevisiae)"
                     /db_xref="GeneID:66875"
                     /db_xref="MGI:MGI:1914125"
     exon            1..139
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            140..238
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     CDS             185..2908
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /codon_start=1
                     /product="transcriptional protein SWT1"
                     /protein_id="NP_080095.3"
                     /db_xref="CCDS:CCDS15360.1"
                     /db_xref="GeneID:66875"
                     /db_xref="MGI:MGI:1914125"
                     /translation="MLLCTTSAHKLETVYDHKFLKMSIKESCAKEEKSQKKQTISSPT
                     FNEDKKKGEISAGSTSSEHGVQPVSTKKRKLKADDTDNVYYNANRKNSKRLNVEVFIP
                     KKRLKFSSSTQAVSYLNNNQMTSHSCSSNGTKDTKVKDCKLTNIGSKLNYEIKNHSRI
                     KITKDMKSKPVDQTKEKNWPSLLIQKKMKELKKEKNNKDSSEELEKCKKNHLPQNYNF
                     SNMIKESFESGRKKISFKIPKKSSTTLQKLVEEKIFTIDSSKSKSKQEEKQHLQSHQM
                     SLNLARHKTENSFSDSTHKQSVCERIRKDHCEHQGTSSSDSKENHAQSFETPCSSVSS
                     EDTQDADEEMQIVEELHAARVGRSVDLPVVPPSGELMSMEIDLVDEDAHPSAAHTASD
                     TKLLIVMDTNVLMNHLKFVKILKTTEIPGFDTLVLIIPWVVIQELDRMKAGKLLKHVQ
                     HKAVPAIHFINNSLKSQDRKLWGQSLQLASQKLYGLSDENNDDRVLKCCLQYQQLFPC
                     SLVILCTDDRNLRTKGLISGVKSLSKEDLDTEILNLTLNTDLCHQPCISKQQLNAEVP
                     PAKETPKEGAANSGLSILLERIICDLEKCLGTALSSILETEMKIAFGNLWMEVLYLKP
                     PWTLINLLQCFKKHWLAVFGLVMENNLLVTVESLYENLCKANKAVDFTTVKFLLQDSK
                     SLLHAFSTRSNYDGVLPQTFAQVNKLLQVLAEVKTKLKPSSSESTRSKEQEDTSLVKL
                     HNQDVNVFLDSNLPQATRHQEIWSVLESVWMSIYQNSTDVFQTLDSSSTLTTSKIASF
                     EEAFVYLQKLMVAVKDILEGIQRILAPNSNYQDVETLYNFLIKYEVNKNVKFTARELY
                     DCVSQTEYRERLTIGCRQLIEMECTMQQCSASVYMEARSRGWCEDMLNNRP"
     exon            239..325
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            326..409
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            410..465
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            466..1153
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            1154..1213
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            1214..1343
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            1344..1445
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            1446..1634
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            1635..1728
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            1729..1874
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            1875..2038
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            2039..2177
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            2178..2326
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            2327..2514
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            2515..2646
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            2647..2713
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            2714..2778
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
     exon            2779..3668
                     /gene="Swt1"
                     /gene_synonym="1200016B10Rik; C1orf26"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagcgttcgg ctcctggcgg gggtccgagt acagaactac atttcccagt gtgcagcggg
       61 ctctgggaag gcgctttggg tgtccgactg gtccggggaa tcgccactgt cgctgtggct
      121 gctgctgccg cggactcaga ccctgtgatg tttccagtct ttggctactg tatcctagca
      181 caggatgctg ctttgtacta ccagtgctca caagcttgag actgtttatg accataagtt
      241 tctaaagatg tctatcaaag aatcttgtgc aaaggaagaa aagtctcaga aaaaacagac
      301 tatctcttca ccaactttta atgaagacaa gaaaaaggga gaaatctcag caggttctac
      361 tagttcagaa catggcgttc agcctgtttc aaccaagaag agaaaactga aagcagatga
      421 tacagacaat gtatactata atgcaaacag aaaaaacagt aaaagattga atgtagaagt
      481 tttcattcct aaaaagagac taaaattcag ttcttcgacc caagcggtat catatttaaa
      541 taataatcaa atgacttcac acagttgttc atcaaatgga actaaagata ctaaagttaa
      601 agattgtaaa ttgacaaata ttggaagtaa gcttaattat gaaattaaaa accatagccg
      661 cattaaaatt accaaagata tgaaatctaa acctgtagac cagacaaagg aaaagaattg
      721 gccttctttg cttattcaga agaagatgaa agaactcaag aaagaaaaaa ataataaaga
      781 cagttctgaa gaattggaga aatgcaagaa aaatcacctt cctcagaatt ataattttag
      841 caatatgatc aaggaatcat ttgaatcagg aagaaagaag attagcttca aaattccaaa
      901 aaaatcctct actaccctcc agaagcttgt cgaagaaaag atctttacta tagattctag
      961 caagtcaaag agtaagcagg aggagaagca acacttgcaa agtcaccaga tgtcattaaa
     1021 tctggccagg cacaaaactg aaaactcatt ttcagattct acacataagc agtctgtttg
     1081 tgagaggata agaaaggacc attgtgagca ccaaggaacg agtagttccg attctaagga
     1141 aaaccatgcc cagagttttg aaacaccatg ttcttcagtg tcatctgagg atacccaaga
     1201 tgcagatgaa gagatgcaga tagtagaaga gctccacgct gcacgtgtcg ggagaagcgt
     1261 ggatctgcct gtggttccac cgtctggaga gctcatgagc atggagattg acctggtgga
     1321 tgaggacgca catccctctg ctgcacacac tgcctcagac acgaagcttc tcattgttat
     1381 ggacacaaat gttctcatga atcatctcaa attcgttaaa attttgaaga cgacagaaat
     1441 accaggattt gacacacttg tgttaataat tccttgggtg gttatacaag agctagatcg
     1501 tatgaaggca ggaaaattac taaaacatgt tcagcataaa gctgtacctg caattcattt
     1561 tatcaacaac agcctcaaaa gtcaagacag aaagctgtgg ggccagtcat tacagctggc
     1621 atcccaaaaa ctttatggac tgagtgacga gaacaatgat gaccgagtat taaagtgctg
     1681 tcttcagtac cagcaattat tcccgtgttc tcttgttatt ctgtgcacgg atgatagaaa
     1741 tttaagaact aaaggcctga taagtggtgt gaagtccctc agtaaagaag atctggatac
     1801 agagatatta aatttaactc tgaacacaga tttgtgtcat cagccttgta tttctaagca
     1861 gcagttgaac gcagaagtac cacctgcgaa agagactcct aaggaaggag ctgcaaattc
     1921 cggactgtcc attctactgg agcggatcat ttgtgatctt gaaaaatgcc ttgggacagc
     1981 tttatcttca atattagaaa cagaaatgaa aattgctttt ggaaatcttt ggatggaggt
     2041 gctgtatttg aaaccaccat ggactctaat aaatctatta cagtgcttta aaaaacattg
     2101 gctggctgta tttggattag ttatggaaaa taacttgctt gtaactgttg agagcctata
     2161 tgaaaatctc tgtaaagcaa ataaggcagt ggattttaca acagtgaaat tcttgcttca
     2221 ggattctaaa agtttgttac atgccttcag tacaaggtca aattatgatg gagttcttcc
     2281 ccagaccttt gctcaagtaa acaaactact gcaagtactc gcagaggtca agacaaaact
     2341 gaagccaagt tcttcagaaa gcacaaggag taaagagcag gaagacactt ctttggtgaa
     2401 gcttcataac caagatgtca acgttttcct ggattctaat cttccccagg ccaccaggca
     2461 tcaggaaatc tggtctgtcc tggagagtgt ttggatgtca atatatcaga acagcacaga
     2521 tgtatttcaa acactggact caagttcaac cctgacaact tcgaaaatag catcctttga
     2581 agaagctttt gtgtatcttc aaaagttaat ggtggctgtg aaagatattc ttgaaggaat
     2641 tcaaaggatt ttggctccta atagtaatta ccaagatgtt gagactctct ataacttcct
     2701 aatcaagtat gaggtaaaca aaaatgtcaa attcactgcc cgggaacttt atgattgtgt
     2761 ttctcagact gagtaccggg aaagattaac cattggatgc cgccagctga ttgagatgga
     2821 atgcaccatg cagcagtgca gtgcatctgt ctatatggag gccagaagca gagggtggtg
     2881 tgaagacatg ctcaacaaca ggccttaagt ttacagcagg aacagcatct ctgtcttcat
     2941 aagtgacaca gtaactttta acctggttgc tttttttgaa aaaaaaaaaa gaaaaaaaaa
     3001 aaacatttca tagatacaaa aaccaaaatg ttgtattgac caatctcatt gaatctagtg
     3061 tagtataaac tgtaccccag ctcttctgga gttgacaata cttcctacct ctaaggagaa
     3121 gagagagagc catcttctca gtgttcctga ggcaggaatc actgtgacac gatggcagcc
     3181 cacagcctta gtatctctcc taaccctgaa tgtgaacaca tgaccagaca ctgccaaacc
     3241 ccaagactta agacatgacc atgccaccac attccacatg ggctgctttc atgaacaaac
     3301 tgtcatttat ataaaactgg tgggaaaacc caccacctct ttcagggaca tgaagtagaa
     3361 ttttgaacta gcaccttctc tgtagctgct ttggcgatgt catttcctgt gcgtttccag
     3421 taggaaagag cccctctgat gcttcccctt acatgtgaag cgctggattt ggggaattga
     3481 acggcagtgg cagctatttg ccctacctaa aactcaagtg tttaattgac ttagttacac
     3541 attaagttgg aaatccttgt ttactggagt gtattatgct tttgttaata tattagatga
     3601 aatcaaattt gatattctat aatgttaatt tatttttaaa acagcaataa ataagttatt
     3661 ttagtagc
//
