LOCUS       NM_001160345            3077 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus small VCP/p97-interacting protein (Svip), transcript
            variant 1, mRNA.
ACCESSION   NM_001160345
VERSION     NM_001160345.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3077)
  AUTHORS   Wu,J., Peng,D., Voehler,M., Sanders,C.R. and Li,J.
  TITLE     Structure and expression of a novel compact myelin protein - small
            VCP-interacting protein (SVIP)
  JOURNAL   Biochem Biophys Res Commun 440 (1), 173-178 (2013)
   PUBMED   24055875
  REMARK    GeneRIF: SVIP and valosin containing protein were seen to be
            co-localized in neuronal cell bodies.
REFERENCE   2  (bases 1 to 3077)
  AUTHORS   Wang,Y., Ballar,P., Zhong,Y., Zhang,X., Liu,C., Zhang,Y.J.,
            Monteiro,M.J., Li,J. and Fang,S.
  TITLE     SVIP induces localization of p97/VCP to the plasma and lysosomal
            membranes and regulates autophagy
  JOURNAL   PLoS One 6 (8), e24478 (2011)
   PUBMED   21909394
  REMARK    GeneRIF: SVIP plays a regulatory role in p97 subcellular
            localization and is a novel regulator of autophagy.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK158571.1 and BX511488.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the functional protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK158571.1, SRR1660821.105050.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3053              AK158571.1         1-3053
            3054-3077           BX511488.1         460-483
FEATURES             Location/Qualifiers
     source          1..3077
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 32.91 cM"
     gene            1..3077
                     /gene="Svip"
                     /gene_synonym="1700006C13Rik; 6620401M08Rik"
                     /note="small VCP/p97-interacting protein"
                     /db_xref="GeneID:75744"
                     /db_xref="MGI:MGI:1922994"
     exon            1..281
                     /gene="Svip"
                     /gene_synonym="1700006C13Rik; 6620401M08Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             228..461
                     /gene="Svip"
                     /gene_synonym="1700006C13Rik; 6620401M08Rik"
                     /codon_start=1
                     /product="small VCP/p97-interacting protein"
                     /protein_id="NP_001153817.1"
                     /db_xref="CCDS:CCDS57551.1"
                     /db_xref="GeneID:75744"
                     /db_xref="MGI:MGI:1922994"
                     /translation="MGLCFPCPAESAPPSPSPEEKREKLAEAAERRQKEAATRGILDI
                     QSVEAKKKKKEQLEKQMATSGPPTAGGLRWTVS"
     exon            282..332
                     /gene="Svip"
                     /gene_synonym="1700006C13Rik; 6620401M08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            333..446
                     /gene="Svip"
                     /gene_synonym="1700006C13Rik; 6620401M08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            447..3063
                     /gene="Svip"
                     /gene_synonym="1700006C13Rik; 6620401M08Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      599..604
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Svip"
                     /gene_synonym="1700006C13Rik; 6620401M08Rik"
                     /note="hexamer: AATATA"
     polyA_site      619
                     /gene="Svip"
                     /gene_synonym="1700006C13Rik; 6620401M08Rik"
                     /note="major polyA site"
     regulatory      2698..2703
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Svip"
                     /gene_synonym="1700006C13Rik; 6620401M08Rik"
                     /note="hexamer: AGTAAA"
     polyA_site      2724
                     /gene="Svip"
                     /gene_synonym="1700006C13Rik; 6620401M08Rik"
     regulatory      2932..2937
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Svip"
                     /gene_synonym="1700006C13Rik; 6620401M08Rik"
                     /note="hexamer: CATAAA"
     polyA_site      2960
                     /gene="Svip"
                     /gene_synonym="1700006C13Rik; 6620401M08Rik"
     regulatory      2985..2990
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Svip"
                     /gene_synonym="1700006C13Rik; 6620401M08Rik"
                     /note="hexamer: ATTATA"
     polyA_site      3012
                     /gene="Svip"
                     /gene_synonym="1700006C13Rik; 6620401M08Rik"
     regulatory      3032..3037
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Svip"
                     /gene_synonym="1700006C13Rik; 6620401M08Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3054
                     /gene="Svip"
                     /gene_synonym="1700006C13Rik; 6620401M08Rik"
ORIGIN      
        1 gcttgaaatt gggcggagct tgtggtggtg ttcgcggggg agggggggcg aggaggaggg
       61 ggaggggcgc ttgcgcctca gatggggtgg gtcttactgc ggggcaggtc ctggcgcggg
      121 gcggagcttt gcagcaggtc aggtgggggc ggggtttgct cctgggcggg gcctgctgca
      181 gcccccagcg aggattcggg ttcccggccc tgggtgcctg cgtccccatg gggctgtgct
      241 tcccttgtcc cgcggagtcc gcaccaccat ccccgagccc ggaagagaaa agagaaaagc
      301 tggcagaggc agcagaaaga aggcagaagg aggcggcgac tcgggggatt ttggacatcc
      361 agtcagtgga ggcaaaaaag aagaagaagg aacagttaga aaagcagatg gcgacatcgg
      421 ggccaccaac ggcaggggga cttagatgga cggtgtcatg aagtatatca gacctggaag
      481 agaatcctgc caccaactcc ggcaactgca gtcaatggct ttcagctgat gtctcctctt
      541 aacacacatt aagagtcaga ctgtgtcatt agtgcccttt cgtgcaatcc tgacactaaa
      601 tatactaaat gtacaaaaat attggtaata tttttatttt caaacttact aaataaccta
      661 gcttttcatt ctattccact ttccctacat ctattttctc ttctgcagga agtaactttg
      721 cagtttttgt agttaaaata tggatccaaa aggtatatat gcatggcgtg tcctggtcgt
      781 acatatatct ccagtgttga gtttgctgct atacctctgc attataagta atcttgctcc
      841 ctagagtcat gtggcatagc ctgtggtcta tctctgtctc actaaatagg aagacttcag
      901 cttccagact tagtgccttt aagctgatca tcagggaaaa tcctgaagac gcatttgaag
      961 gacttcaggt gaaggaagtc tttattttta taacccacta agaaatgaat atttgtaggc
     1021 aaatgttaac tctctgctaa tttattttgt gtacctaagg catatcatat taacgtgaag
     1081 ttacatgtcc gtaggacgtc agctcagtga cctgctgatg agtcctgcta gaagcatgaa
     1141 ggtatgtgta gtgaagggat gaggccaact gagaaccagg ttggagaaaa tgagtgataa
     1201 tagatgtgtt caaattccac aagcattttt attcttctgt atttatcaaa gaacagttgt
     1261 aagatctata caaacatggt gttgccaatg aaagtgtgaa agaaacatgt gagttctgta
     1321 cttggaaagt ccaagcctgt caaagcacgc ttgtgattta tgacattgtc gcttgttttc
     1381 ttcttactac gtaataagcg aagatgcaag tgtgcaaggc tgctgctgct atcgatgcca
     1441 agacattcag tgctaacatc cagtccttac cttagaattt atagattcta gccagtcaga
     1501 aatctcagtg aattaggcaa agtcacagcc ataagaagaa actgagccat tggcttgtct
     1561 gttcctctcc caaggtatct gacggtgtgt cacacatgct ctttttaaag aattggagct
     1621 ataatatagg tctcataatg actgaagtat tacttttctg tcgctcaaaa tgtttcatga
     1681 atagctaggt aagacataga attgtatcat ctcagtttcc ttcatttaga gatggtgata
     1741 tttttcttcc taaatgatag tgatatcaat aagctgactt ttagaaataa ttcttagctc
     1801 attttggtaa gtaatatttc tgacatagga aagctgactc agctgaatgg ggagagaggc
     1861 agcacacacc agccctcacc atgggaagcc ctcctcctgt tagaacagac atctcgttct
     1921 cttcccttca tcgtagacca tggctcgtgc aaagagaagg cttggttcag tgggcagtgc
     1981 tacatttatt acgtaagggc atgtctagag gcacaagtgc catacaggtt tattccttgc
     2041 ttggaataat taggatacac tgcttttggc atctgtgggc tccctctgct gttccaaggc
     2101 cctgtgcatg gctatggcct gccccaccga tataagcctt ctcccaaggc cacacatgtc
     2161 gtaggcacta aatggtgatt tgaatctcat gaatgtgatt gaaaagagga agcaggatgc
     2221 ttgataagaa cctgggaaat ggctatttga aatcatatat gcgtctaaac atctttctta
     2281 ggttgtggat agtggtgtag aggtgagttt tctctaactt aagacttaaa taacaaaaca
     2341 taatattgaa tatatcttcc aaatcttatg gcaaaattgg tagaacataa gaaaatccat
     2401 cagatgcaga aagttaacca acatatgcaa gcttcagtct taattgtaat tctgaaactg
     2461 atacagctgg tgataaagag ttaaatatat cattacagaa gggctctgtg actggttgca
     2521 tgttttggaa acatctgtaa atggtttttt ttatctagtt tgtgttatga ttatatctgg
     2581 aatgtgattt attagttttc taatatattt tgagcccaat gttatgtatt ctacattgtc
     2641 tttgggtata tgaacataca tcttcctata caaaagtttc ctttggccat gtctttaagt
     2701 aaaatgtttc tactccatct taaacaaatt gtgacttgtc ttcacacaca gagacgcatc
     2761 catgtctctg gggttgataa cggaaaggga aacaatggct gcctggagaa ggcatgttta
     2821 tcatcctgga aagaagaaat gttattatgt tgttattatt cttgctttta gattaaaagg
     2881 taaagcactg tggaaaggct ctctgcataa tcccagaacc ataaacattt acataaaatt
     2941 tgaatttgtt tatccaaaaa gttggcttat tttcattgtt aagaattata ctgtgtcctt
     3001 ggaagatgaa aagcatacct tgtcattttt gaataaagta tataatttaa cagattggca
     3061 agaaaaaaaa aaaaaaa
//
