LOCUS       NM_001356461            3053 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus sushi domain containing 4 (Susd4), transcript variant
            2, mRNA.
ACCESSION   NM_001356461 XM_006497064
VERSION     NM_001356461.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3053)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3053)
  AUTHORS   Gonzalez-Calvo,I., Iyer,K., Carquin,M., Khayachi,A., Giuliani,F.A.,
            Sigoillot,S.M., Vincent,J., Seveno,M., Veleanu,M., Tahraoui,S.,
            Albert,M., Vigy,O., Bosso-Lefevre,C., Nadjar,Y., Dumoulin,A.,
            Triller,A., Bessereau,J.L., Rondi-Reig,L., Isope,P. and Selimi,F.
  TITLE     Sushi domain-containing protein 4 controls synaptic plasticity and
            motor learning
  JOURNAL   Elife 10, e65712 (2021)
   PUBMED   33661101
  REMARK    GeneRIF: Sushi domain-containing protein 4 controls synaptic
            plasticity and motor learning.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3053)
  AUTHORS   Zhu,H., Meissner,L.E., Byrnes,C., Tuymetova,G., Tifft,C.J. and
            Proia,R.L.
  TITLE     The Complement Regulator Susd4 Influences Nervous-System Function
            and Neuronal Morphology in Mice
  JOURNAL   iScience 23 (3), 100957 (2020)
   PUBMED   32179479
REFERENCE   4  (bases 1 to 3053)
  AUTHORS   Hai,Q., Ritchey,B., Robinet,P., Alzayed,A.M., Brubaker,G., Zhang,J.
            and Smith,J.D.
  TITLE     Quantitative Trait Locus Mapping of Macrophage Cholesterol
            Metabolism and CRISPR/Cas9 Editing Implicate an ACAT1 Truncation as
            a Causal Modifier Variant
  JOURNAL   Arterioscler Thromb Vasc Biol 38 (1), 83-91 (2018)
   PUBMED   29097366
REFERENCE   5  (bases 1 to 3053)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   6  (bases 1 to 3053)
  AUTHORS   Tu,Z., Cohen,M., Bu,H. and Lin,F.
  TITLE     Tissue distribution and functional analysis of Sushi
            domain-containing protein 4
  JOURNAL   Am J Pathol 176 (5), 2378-2384 (2010)
   PUBMED   20348246
  REMARK    GeneRIF: analysis of cloning, expression, refolding, and tissue
            distribution of Sushi domain-containing protein 4
REFERENCE   7  (bases 1 to 3053)
  AUTHORS   Jensen,P., Magdaleno,S., Lehman,K.M., Rice,D.S., Lavallie,E.R.,
            Collins-Racie,L., McCoy,J.M. and Curran,T.
  TITLE     A neurogenomics approach to gene expression analysis in the
            developing brain
  JOURNAL   Brain Res Mol Brain Res 132 (2), 116-127 (2004)
   PUBMED   15582152
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC151579.2 and AC170917.2.
            
            On Oct 5, 2017 this sequence version replaced XM_006497064.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK088629.1, SRR7345562.3823151.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-181               AC151579.2         160109-160289
            182-364             AC151579.2         160899-161081
            365-577             AC170917.2         140415-140627       c
            578-751             AC170917.2         119560-119733       c
            752-940             AC170917.2         115080-115268       c
            941-1132            AC170917.2         86159-86350         c
            1133-1277           AC170917.2         84778-84922         c
            1278-1660           AC170917.2         81425-81807         c
            1661-3053           AC170917.2         77099-78491         c
FEATURES             Location/Qualifiers
     source          1..3053
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 85.94 cM"
     gene            1..3053
                     /gene="Susd4"
                     /gene_synonym="E430021N18Rik"
                     /note="sushi domain containing 4"
                     /db_xref="GeneID:96935"
                     /db_xref="MGI:MGI:2138351"
     exon            1..181
                     /gene="Susd4"
                     /gene_synonym="E430021N18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            182..364
                     /gene="Susd4"
                     /gene_synonym="E430021N18Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             217..1689
                     /gene="Susd4"
                     /gene_synonym="E430021N18Rik"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 2; sushi domain-containing protein 4"
                     /codon_start=1
                     /product="sushi domain-containing protein 4 isoform 1
                     precursor"
                     /protein_id="NP_001343390.1"
                     /db_xref="CCDS:CCDS15590.1"
                     /db_xref="GeneID:96935"
                     /db_xref="MGI:MGI:2138351"
                     /translation="MYHGMNPSNGDGFLEQQLQQQQPQSPQRLLAVILWFQLALCFGP
                     AQLTGGFDDLNVCADPGVPENGFRTPSGGVFFESSVTRFHCQDGFRLKGSTKRLCMKH
                     FNGTLGWVPSDKPVCIQEDCRIPQIEDAEIRNKTYRHGEKLVIDCHEGFKIRYPDLYN
                     LVSLCRDDGTWDNLPICQGCLRPLASSNGYVNISEFQTSFPVGTVIAYRCFPGFKLEG
                     SENLECLHNLIWSSSPPRCLALEVCPLPPMVSHGDFICHPRPCERYNHGTVVEFYCDP
                     GYSLTSDYKYITCQYGEWFPSYQVYCIKSEQTWPSTHETLLTTWKIVAFTATSVLLVL
                     LLVILARMFQTKFKAHFPPRGPPRSSSSDPDFVVVDGVPVMLPTYDEAVNGSSSALGP
                     GYPASVGQGCPLPVDDQSPPAYPGSGDTDTGPGESETCDSTSGSSEMLQSLYSPPMCQ
                     GGSRPAPDTPDTISSTAGEVASTSPGIDIADEIPLMEEDP"
     exon            365..577
                     /gene="Susd4"
                     /gene_synonym="E430021N18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            578..751
                     /gene="Susd4"
                     /gene_synonym="E430021N18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            752..940
                     /gene="Susd4"
                     /gene_synonym="E430021N18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1132
                     /gene="Susd4"
                     /gene_synonym="E430021N18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1133..1277
                     /gene="Susd4"
                     /gene_synonym="E430021N18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1278..1660
                     /gene="Susd4"
                     /gene_synonym="E430021N18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1661..3053
                     /gene="Susd4"
                     /gene_synonym="E430021N18Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3033..3038
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Susd4"
                     /gene_synonym="E430021N18Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3053
                     /gene="Susd4"
                     /gene_synonym="E430021N18Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggtgtagccc ggcagccgcc gaggcttccg tctcgctcgc tcgctcgctc ctctgtcttg
       61 ctcgctcgct cgcttgcttg ctcgcgcaga ggcggcagca gaggtcgcgc acagatgcgg
      121 gttagactgg cggggggagg aggcggagga gggaaggaag ctgcatgcat gagacccaca
      181 gactctcgca agctggatgc cctctgtgga tgaaagatgt atcatggaat gaacccgagc
      241 aatggagatg gatttctaga gcagcagctg cagcaacagc agcctcagtc cccccagaga
      301 ctcttggccg tgatcctgtg gtttcaactg gcgctgtgct ttggccctgc acagctcacg
      361 ggtgggttcg atgacctcaa cgtgtgtgct gacccaggcg tcccagagaa tggcttcagg
      421 acccccagcg gaggagtttt cttcgaaagc tcagtaaccc gatttcactg ccaagacgga
      481 ttcaggctga agggctctac aaagaggctg tgtatgaaac attttaatgg gaccctaggc
      541 tgggtcccaa gtgacaaacc tgtctgcata caagaagact gccgcatccc ccaaattgaa
      601 gatgctgaga ttcgaaacaa gacgtacaga cacggagaga agttagtcat tgactgtcac
      661 gaggggttca agatccgcta ccctgacctg tacaacctgg tttcgttatg ccgtgacgat
      721 gggacatggg ataacctgcc catctgtcaa ggctgcctga gacctctagc ctcttccaat
      781 ggctacgtga acatctccga gttccagacc tccttccctg tgggaactgt gatcgcctat
      841 cgctgcttcc ctggatttaa actcgagggt tccgagaacc tcgagtgctt acacaacctt
      901 atctggtcgt ccagcccacc ccggtgcctt gctctggaag tttgtccact acctcctatg
      961 gtaagtcacg gagatttcat ctgccacccg aggccttgtg agcgctacaa ccatggaact
     1021 gtggtggagt tctactgtga tcctggctac agcctcacca gtgactacaa gtacatcacc
     1081 tgccagtatg gagagtggtt tccttcctac caagtctact gcatcaaatc agaacaaacg
     1141 tggcccagca cccacgagac cctcctgacc acgtggaaga tcgtggcgtt cacagccacc
     1201 agcgtgctgc tggtgttact gctcgtcatc ctggccagaa tgttccagac caagttcaag
     1261 gcccacttcc ccccgagggg tcctcccagg agttccagca gtgaccccga ctttgtggtc
     1321 gtggatggag tgcccgtcat gctcccgacc tatgatgagg ctgtgaacgg tagctcgagt
     1381 gccttaggcc cggggtaccc ggcctccgtg ggccagggct gtcctttacc tgtggatgac
     1441 cagagccctc cagcataccc cggctccggg gacacggaca caggccctgg ggagtcagaa
     1501 acctgtgaca gtacttcggg ttcctcggag atgctccaga gtctatattc accccccatg
     1561 tgccaagggg gcagccgccc tgccccggac acccctgaca cgatttcaag cacagcaggg
     1621 gaggtggcat ccacaagccc gggcatcgac attgcagatg agatcccgct catggaagag
     1681 gacccatagc ctggtgacat cctgctagtc ccactgtccc ctttggggaa aagagccttg
     1741 aagagagacc acaggaggac agagcttggg gaccaggggt catttttaat ctatctacat
     1801 aaggacagtg attcataccg tacatctcca gcaggactgt gggtctggcc aacagcaaag
     1861 gcggtgcttt caaatgagac tcaagggttt atcatgacca gcagggaacc aagtgcagag
     1921 gggactctct ctgcctcacc cctgtgtcag agctgggtgt ctcttgctac agagcgtgag
     1981 actgtgccac acacatcctg ttgctcctgc taacagcact ccctgctcct ctgaaagcat
     2041 gtcacattgt ataaatttgc ttctaaaatc tgctttgaac tgtctaggga ctttagatct
     2101 ggacgggtca gcctctgtaa aaaaaaaaaa aagcccacgt tgacctgcaa acccaagagc
     2161 agatcctctc tttgcccttc ttagtaaggg acgggctccc aaggaaagac tctcatgtga
     2221 cactcagacc atctcttaca cctggacagc caatcaaagc aggatgtggc ggcttgaacg
     2281 agaaaggaaa ggataaacaa gccaactccg ctttctgaaa atttcttcat gccaagcccc
     2341 tatgctctgt gctgccccct ggtgacatgt ttgtaggcgt ggtctggcag tggacctgcg
     2401 gtgtggaata gacccgtggc tttacacatg gtgagaacac gttcagatgc atcttgtggt
     2461 ggaccccgta acctggtcat gtttggtttt ggcatttggc agactccact caaatttatc
     2521 tgctcatgcc ttcctatgtg ggtcattgct gtcactctac cccgacccta aaacctaacc
     2581 attcttttat tttccaaagt ggaaagtttc tgtaaacacg gtctgcattt ggagggagaa
     2641 ggaagcggga gccggatctt ttgagaccac tcccagcccc tcagctctct tttttgtcct
     2701 gctcagtcca aaggctggcc tcccagcccc aagccaccct gccctcttgc tttcgggggg
     2761 cctttggccc tgcctgcctg ccatcccgta tttccatgag ggtctcatgg cacccactgg
     2821 gtgttgtgcc taagcaattg tttgattttt tttaagagcc tcgagtccag aagtgtctct
     2881 tcaaatacat gttggtccat ggtgtcgttt ccatccctcc tctgggttgt agacaaatat
     2941 gaacaaaact ctcatccaat agaatcactg tgctgctaga gcaccgaggg acggaggctt
     3001 gatcgaatcc tgttttctct caacacagac tgattaaaaa ttaaaaaaga aaa
//
