LOCUS       NM_011512               2863 bp    mRNA    linear   ROD 03-APR-2023
DEFINITION  Mus musculus surfeit gene 4 (Surf4), mRNA.
ACCESSION   NM_011512
VERSION     NM_011512.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2863)
  AUTHORS   Tao G, Wang H, Shen Y, Zhai L, Liu B, Wang B, Chen W, Xing S, Chen
            Y, Gu HM, Qin S and Zhang DW.
  TITLE     Surf4 (Surfeit Locus Protein 4) Deficiency Reduces Intestinal Lipid
            Absorption and Secretion and Decreases Metabolism in Mice
  JOURNAL   Arterioscler Thromb Vasc Biol 43 (4), 562-580 (2023)
   PUBMED   36756879
  REMARK    GeneRIF: Surf4 (Surfeit Locus Protein 4) Deficiency Reduces
            Intestinal Lipid Absorption and Secretion and Decreases Metabolism
            in Mice.
REFERENCE   2  (bases 1 to 2863)
  AUTHORS   Tang VT, McCormick J, Xu B, Wang Y, Fang H, Wang X, Siemieniak D,
            Khoriaty R, Emmer BT, Chen XW and Ginsburg D.
  TITLE     Hepatic inactivation of murine Surf4 results in marked reduction in
            plasma cholesterol
  JOURNAL   Elife 11, e82269 (2022)
   PUBMED   36193893
  REMARK    GeneRIF: Hepatic inactivation of murine Surf4 results in marked
            reduction in plasma cholesterol.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2863)
  AUTHORS   Shen Y, Gu HM, Zhai L, Wang B, Qin S and Zhang DW.
  TITLE     The role of hepatic Surf4 in lipoprotein metabolism and the
            development of atherosclerosis in apoE-/- mice
  JOURNAL   Biochim Biophys Acta Mol Cell Biol Lipids 1867 (10), 159196 (2022)
   PUBMED   35803528
  REMARK    GeneRIF: The role of hepatic Surf4 in lipoprotein metabolism and
            the development of atherosclerosis in apoE(-/-) mice.
REFERENCE   4  (bases 1 to 2863)
  AUTHORS   Wu L, He S, Ye W, Shen J, Zhao K, Zhang Y, Zhang R, Wei J, Cao S,
            Chen K, Le R, Xi C, Kou X, Zhao Y, Wang H, Kang L and Gao S.
  TITLE     Surf4 facilitates reprogramming by activating the cellular response
            to endoplasmic reticulum stress
  JOURNAL   Cell Prolif 54 (11), e13133 (2021)
   PUBMED   34585448
  REMARK    GeneRIF: Surf4 facilitates reprogramming by activating the cellular
            response to endoplasmic reticulum stress.
            Erratum:[Cell Prolif. 2022 Jan;55(1):e13177. PMID: 35060635]
REFERENCE   5  (bases 1 to 2863)
  AUTHORS   Wang B, Shen Y, Zhai L, Xia X, Gu HM, Wang M, Zhao Y, Chang X,
            Alabi A, Xing S, Deng S, Liu B, Wang G, Qin S and Zhang DW.
  TITLE     Atherosclerosis-associated hepatic secretion of VLDL but not PCSK9
            is dependent on cargo receptor protein Surf4
  JOURNAL   J Lipid Res 62, 100091 (2021)
   PUBMED   34118252
  REMARK    GeneRIF: Atherosclerosis-associated hepatic secretion of VLDL but
            not PCSK9 is dependent on cargo receptor protein Surf4.
REFERENCE   6  (bases 1 to 2863)
  AUTHORS   Garson K, Duhig T, Armes N, Colombo P and Fried M.
  TITLE     Surf5: a gene in the tightly clustered mouse surfeit locus is
            highly conserved and transcribed divergently from the rpL7A (Surf3)
            gene
  JOURNAL   Genomics 30 (2), 163-170 (1995)
   PUBMED   8586415
REFERENCE   7  (bases 1 to 2863)
  AUTHORS   Reeves JE and Fried M.
  TITLE     The surf-4 gene encodes a novel 30 kDa integral membrane protein
  JOURNAL   Mol Membr Biol 12 (2), 201-208 (1995)
   PUBMED   7540914
REFERENCE   8  (bases 1 to 2863)
  AUTHORS   Yu LC, Chen JL, Tsai WB and Chen YH.
  TITLE     Primary structure and characterization of an androgen-stimulated
            autoantigen purified from mouse seminal-vesicle secretion
  JOURNAL   Biochem J 296 (Pt 3) (Pt 3), 571-576 (1993)
   PUBMED   8280054
REFERENCE   9  (bases 1 to 2863)
  AUTHORS   Huxley C and Fried M.
  TITLE     The mouse surfeit locus contains a cluster of six genes associated
            with four CpG-rich islands in 32 kilobases of genomic DNA
  JOURNAL   Mol Cell Biol 10 (2), 605-614 (1990)
   PUBMED   2300057
REFERENCE   10 (bases 1 to 2863)
  AUTHORS   Giallongo A, Yon J and Fried M.
  TITLE     Ribosomal protein L7a is encoded by a gene (Surf-3) within the
            tightly clustered mouse surfeit locus
  JOURNAL   Mol Cell Biol 9 (1), 224-231 (1989)
   PUBMED   2648130
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DV656434.1, BB854341.1 and AK145670.1.
            
            [WARNING] On May 11, 2023 this sequence was replaced by
            NM_011512.4.
            
            On Apr 23, 2009 this sequence version replaced NM_011512.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK145670.1, SRR1660819.183903.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-53                DV656434.1         15-67
            54-60               BB854341.1         6-12
            61-2863             AK145670.1         2-2804
FEATURES             Location/Qualifiers
     source          1..2863
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 19.1 cM"
     gene            1..2863
                     /gene="Surf4"
                     /gene_synonym="Surf-4"
                     /note="surfeit gene 4"
                     /db_xref="GeneID:20932"
                     /db_xref="MGI:MGI:98445"
     exon            1..237
                     /gene="Surf4"
                     /gene_synonym="Surf-4"
                     /inference="alignment:Splign:2.1.0"
     CDS             190..999
                     /gene="Surf4"
                     /gene_synonym="Surf-4"
                     /codon_start=1
                     /product="surfeit locus protein 4"
                     /protein_id="NP_035642.1"
                     /db_xref="CCDS:CCDS15817.1"
                     /db_xref="GeneID:20932"
                     /db_xref="MGI:MGI:98445"
                     /translation="MGQNDLMGTAEDFADQFLRVTKQYLPHVARLCLISTFLEDGIRM
                     WFQWSEQRDYIDTTWSCGYLLASSFVFLNLLGQLTGCVLVLSRNFVQYACFGLFGIIA
                     LQTIAYSILWDLKFLMRNLALGGGLLLLLAESRSEGKSMFAGVPTMRESSPKQYMQLG
                     GRVLLVLMFMTLLHFDASFFSIIQNIVGTALMILVAIGFKTKLAALTLVVWLFAINVY
                     FNAFWTIPVYKPMHDFLKYDFFQTMSVIGGLLLVVALGPGGVSMDEKKKEW"
     exon            238..424
                     /gene="Surf4"
                     /gene_synonym="Surf-4"
                     /inference="alignment:Splign:2.1.0"
     exon            425..501
                     /gene="Surf4"
                     /gene_synonym="Surf-4"
                     /inference="alignment:Splign:2.1.0"
     exon            502..545
                     /gene="Surf4"
                     /gene_synonym="Surf-4"
                     /inference="alignment:Splign:2.1.0"
     exon            546..732
                     /gene="Surf4"
                     /gene_synonym="Surf-4"
                     /inference="alignment:Splign:2.1.0"
     exon            733..2863
                     /gene="Surf4"
                     /gene_synonym="Surf-4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctggagcgt gagggcgcgc ggcaggcggg gcggggcgcg gcgggaggcg cggtcccttt
       61 aaggcttggc ctacgtggca gccgctagag cagccgcggc tcagcgaggc cggccgccgg
      121 gtacttcctg tggaggccgc agcaggcgcg agcgcccagg acctgccagc tgagccttcc
      181 gccgccgcca tgggacagaa cgacctgatg ggcacggccg aggacttcgc cgaccagttc
      241 cttcgagtca ccaagcagta cctgcctcat gtggcgcgcc tctgcctgat cagcaccttc
      301 ctggaggatg gcatccgcat gtggttccag tggagtgagc agcgtgacta tatcgacacc
      361 acctggagct gtggctacct gttggcctca tccttcgtgt tcctcaacct gctgggacaa
      421 ttgactggct gtgttttggt gctgagcagg aacttcgtgc agtatgcctg ctttgggctg
      481 tttggaatca tcgcactgca gacaattgcc tatagcattt tgtgggactt gaagtttctc
      541 atgaggaacc tggctttagg aggaggtttg ctgctgctct tggcagaatc ccgctcagaa
      601 gggaagagca tgtttgctgg tgtcccaacc atgcgtgaga gctcccccaa gcagtacatg
      661 cagcttggag gaagggtcct gctggtcctg atgttcatga ccctccttca ctttgatgcc
      721 agcttctttt ctatcatcca gaacattgtg ggcacagctc tgatgatctt agtagccatc
      781 ggttttaaaa ccaagctggc agctttgact ctcgtcgtct ggctgtttgc catcaacgtg
      841 tatttcaacg ccttctggac aatcccggta tataaaccca tgcatgactt cctgaaatac
      901 gacttcttcc agaccatgtc agtgattgga ggcctgctcc tggtggtggc tcttggccca
      961 gggggtgtgt ccatggatga gaagaagaaa gagtggtaac acacagatcc ctcccctccc
     1021 tggctgaggc acagggccct ggcctggttc agggcagagt caacaaactg ccggcgtttg
     1081 tgtgtccttc tcccttcccc tcccttggta aaggcacaga tgttttgaga actttatttg
     1141 cagacacctg aaaattggag ataaaatctt tggaaatagt ctggagtctt gactgtccag
     1201 ggctggcgag ctggatggtc actccttagc caaggcttgg aggagacagc gtgctgggct
     1261 gtggcctcat tcctcctgtc tccgagttcc ttttggggaa gtcgtactga gctgtatttt
     1321 tatcattcaa agcagtttcc cttcttagtt ttgagtttac atccttagct caaactacta
     1381 aatgacttag gatagtccag ccaaacacca aacggttaaa cctccagttc agaattctac
     1441 cagtggcccc agcattgctt ctgcccctgt attttatagg atcagtgaag atgttagaga
     1501 aaccaagtca agagaacagt acagtattgg aaaggtgggt gttactgctg tcccaagtcc
     1561 ttgatgttag ctagctggat gctgtttact gggtgaaagg taccttggga gttttcatgg
     1621 ctccaagcag ggatgggatg gggtaagcag caggaagttc ttagaaagct gctatccctc
     1681 aagcttggtg gtggaaaggg caggagagca ggctgctcac aggatggccc acacaaccac
     1741 catggaacca gcctgggaac agcgatgcca tggggcccag aagtgaggag tcccagtact
     1801 caagacaccc aggctcaacc cagttacctc acacttgacc ttctcagagc aaggcctgaa
     1861 ctccacaggt tgtggtcccc aacccccagc ttaactccct gttccaggct gagccgaccc
     1921 cgtcgacagc cctgatacca ccattcccct gaggctgttg cttgctcaga tttttgtcaa
     1981 cttgctctgc tgtatgcagc caagatactt tttacaattt gtgatgcctt accaatttga
     2041 tctcagtcct gtatttaaag ttttctaaca ttgccttaca ccgtgtttct ctttttgggg
     2101 gaggggtggg gtgtctaatg ctgtggtctt gctcatctgc atggtagtgc catgagggta
     2161 gttgggttcc tcctggatct ctcccaggtc tgttggagag aacagacaga cttagaaccc
     2221 ctggagggaa gctggcagct tacctcaccc ttgggtacag agtcttggag gtcctccttt
     2281 ctggcatcag ctgggtaggc aggactttgt tctctgagtc actttgggtc agtcccttgc
     2341 ctcgctggct ctgcaggctg aattcacctt ctcaacacct agcccatgtt ttcctgcagc
     2401 cttatggcct gcctattcct cccaagtgag ttccagcact ggctcaggcc atgctagttc
     2461 tttaccacag agctgcctca gtgcacagcc acctgcagtg gcagccccat gacattccag
     2521 tctgtggagt ggggcagacc ctgggaggca agtgcatgcc gtgcagcaga agccctcgtc
     2581 ccagggttac ttagcccttt gaccagcctc ctgtgggttc tgcctgggat gggaaccctc
     2641 atcccaaggg tacttggccc atttaccagc ctcctgtggg gtgcgcctgg gacgggagaa
     2701 aacaatgata cacatattgg tttggcaaaa gttttctgaa gatgctttag ctttatgtgg
     2761 gaataggtat aaacctcatt tttatgctgt attttatatc ttagttgtgt ttgaaaatgt
     2821 tttgatcttt ggaaacatca aaataaataa tggcatttgt ggt
//
