LOCUS       NM_009297               6201 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus SPT6, histone chaperone and transcription elongation
            factor (Supt6), mRNA.
ACCESSION   NM_009297 XM_907462
VERSION     NM_009297.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6201)
  AUTHORS   Mayere,C., Neirijnck,Y., Sararols,P., Rands,C.M., Stevant,I.,
            Kuhne,F., Chassot,A.A., Chaboissier,M.C., Dermitzakis,E.T. and
            Nef,S.
  TITLE     Single-cell transcriptomics reveal temporal dynamics of critical
            regulators of germ cell fate during mouse sex determination
  JOURNAL   FASEB J 35 (4), e21452 (2021)
   PUBMED   33749946
REFERENCE   2  (bases 1 to 6201)
  AUTHORS   Bi,X., Xu,Y., Li,T., Li,X., Li,W., Shao,W., Wang,K., Zhan,G.,
            Wu,Z., Liu,W., Lu,J.Y., Wang,L., Zhao,J., Wu,J., Na,J., Li,G.,
            Li,P. and Shen,X.
  TITLE     RNA Targets Ribogenesis Factor WDR43 to Chromatin for Transcription
            and Pluripotency Control
  JOURNAL   Mol Cell 75 (1), 102-116 (2019)
   PUBMED   31128943
REFERENCE   3  (bases 1 to 6201)
  AUTHORS   Oqani,R.K., Lin,T., Lee,J.E., Kang,J.W., Shin,H.Y. and Il Jin,D.
  TITLE     Iws1 and Spt6 Regulate Trimethylation of Histone H3 on Lysine 36
            through Akt Signaling and are Essential for Mouse Embryonic Genome
            Activation
  JOURNAL   Sci Rep 9 (1), 3831 (2019)
   PUBMED   30846735
  REMARK    GeneRIF: Iws1 and Spt6 Regulate Trimethylation of Histone H3 on
            Lysine 36 through Akt Signaling and are Essential for Mouse
            Embryonic Genome Activation.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6201)
  AUTHORS   Orlacchio,A., Stark,A.E., Foray,C., Amari,F., Sheetz,T., Reese,E.,
            Tessari,A., La Perle,K., Palmieri,D., Tsichlis,P.N. and Coppola,V.
  TITLE     Genetic ablation of interacting with Spt6 (Iws1) causes early
            embryonic lethality
  JOURNAL   PLoS One 13 (9), e0201030 (2018)
   PUBMED   30208029
  REMARK    GeneRIF: Iws1 is expressed in all adult organs and it is an
            essential gene for mouse embryonic development.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6201)
  AUTHORS   Ouda,R., Sarai,N., Nehru,V., Patel,M.C., Debrosse,M., Bachu,M.,
            Chereji,R.V., Eriksson,P.R., Clark,D.J. and Ozato,K.
  TITLE     SPT6 interacts with NSD2 and facilitates interferon-induced
            transcription
  JOURNAL   FEBS Lett 592 (10), 1681-1692 (2018)
   PUBMED   29683485
  REMARK    GeneRIF: SPT6 facilitates IFN-induced transcription, highlighting
            its critical role in gene activation.
REFERENCE   6  (bases 1 to 6201)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 6201)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   8  (bases 1 to 6201)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 6201)
  AUTHORS   Chiang,P.W., Wang,S., Smithivas,P., Song,W.J., Ramamoorthy,S.,
            Hillman,J., Puett,S., Van Keuren,M.L., Crombez,E., Kumar,A.,
            Glover,T.W., Miller,D.E., Tsai,C.H., Blackburn,C.C., Chen,X.N.,
            Sun,Z., Cheng,J.F., Korenberg,J.R. and Kurnit,D.M.
  TITLE     Identification and analysis of the human and murine putative
            chromatin structure regulator SUPT6H and Supt6h
  JOURNAL   Genomics 34 (3), 328-333 (1996)
   PUBMED   8786132
REFERENCE   10 (bases 1 to 6201)
  AUTHORS   Chiang,P.W., Baldacci,P.A., Babinet,C., Camper,S.A.,
            Watkins-Chow,D., Baker,D.D., Tsai,C.H., Ramamoorthy,S., King,E.,
            Slack,A.C., Fogel,E., Morahan,G., Ashworth,A., Blackburn,C.C. and
            Kurnit,D.M.
  TITLE     Linkage mapping of murine homolog of the yeast SPT6 gene to MMU11B1
  JOURNAL   Mamm Genome 7 (6), 459-460 (1996)
   PUBMED   8662231
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK136094.1, BC072657.1, AK158846.1 and AK052651.1.
            
            On Jan 25, 2008 this sequence version replaced NM_009297.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U40375.1, SRR1660815.210579.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-80                AK136094.1         641-720
            81-4205             BC072657.1         1-4125
            4206-5922           AK158846.1         2141-3857
            5923-6201           AK052651.1         1077-1355
FEATURES             Location/Qualifiers
     source          1..6201
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 46.74 cM"
     gene            1..6201
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /note="SPT6, histone chaperone and transcription
                     elongation factor"
                     /db_xref="GeneID:20926"
                     /db_xref="MGI:MGI:107726"
     exon            1..156
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            157..295
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            296..454
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            455..531
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            532..724
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            725..809
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            810..1083
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            1084..1185
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            1186..1302
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            1303..1392
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            1393..1535
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            1536..1684
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            1685..1783
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            1784..1913
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            1914..2064
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            2065..2219
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            2220..2415
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            2416..2555
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            2556..2673
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            2674..2750
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            2751..2886
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            2887..3024
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            3025..3192
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            3193..3320
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            3321..3528
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            3529..3676
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            3677..3819
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            3820..3960
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            3961..4156
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            4157..4395
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            4396..4509
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            4510..4634
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            4635..4747
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            4748..4825
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            4826..4992
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            4993..5180
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     exon            5181..6201
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5905..5910
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /note="hexamer: AATAAA"
     polyA_site      5926
                     /gene="Supt6"
                     /gene_synonym="5131400N11Rik; mKIAA0162; SPT6; Supt6h"
                     /note="major polyA site"
ORIGIN      
        1 gttaacgcag cagcggcgac ggtggtggtg gtggtggcgg cggctgcgga gggcccttgc
       61 ggtgggtccg gactatcctt ttgcagtctc tgatcggcga ctccattttc ttcggtggga
      121 gcttagcgta gcggagaagc agcggccttc aagcagtctt caaggaggct gtgagaagca
      181 gcaacaatgt ctgattttgt ggaaagtgag gccgaagagt cagaagaaga atacaatcat
      241 gaaggcgagg tggtacctag agtcaccaag aagtttgtgg aagaggagga tgatgatgag
      301 gaggaggaag aggagaatct agatgatcaa gatgagcgag gcaacctcaa agactttatc
      361 aatgacgatg atgatgaaga agaaggggag gaggatgagg gcagcgactc tggggactca
      421 gaagacgatg ttggccacaa gaagagaaaa cgcccatctt ttgatgaccg cctggaagat
      481 gatgattttg acctcattga ggagaatttg ggtgttaaag tcaaacgagg acaaaaatac
      541 cgacgtgtca aaaaaatgtc tgatgatgat gaagatgatg aagaggaata tggcaaagag
      601 gaacacgaga aggaggccat tgcaggggaa atcttccaag atgaagaagg ggaagaaggc
      661 caggaggctg tagaggcccc catggcccct cctgacgagg aggaggaaga tgatgaggag
      721 tcagacattg acgatttcat tgtggatgat gatggacagc ctctgaaaaa acccaaatgg
      781 cgaaaaaagc tccctggata tacagatgca gccctgcagg aagcccagga gatcttcggt
      841 gtggactttg actatgatga atttgagaaa tacaatgaat acgatgaaga actggaagaa
      901 gactatgagt acgaggatga tgagactgaa ggtgagatcc gagtgcgccc caagaagacc
      961 accaagaaac gtgtgagtcg caggagcatc tttgagatgt acgagcctag tgagctggag
     1021 agcagccacc tcacagacca ggacaatgaa atccgagcca ctgacttgcc tgagaggttc
     1081 cagctccgct ccatcccagt caaggcagct gaggatgatg agctagaaga ggaagctgac
     1141 tggatctata gaaatgcctt cgcaacaccg accatctccc tccaggacag ctgtgattac
     1201 ctagaccgtg ggcagccaac tagtagcttc agtcgtaaag ggcccagcac agttcagaag
     1261 atcaaagagg ccctgggctt catgcggaat cagcattttg aggtgccttt cattgccttc
     1321 taccgaaagg agtatgtgga acctgagctg cacatcaatg acctgtggag ggtgtggcag
     1381 tgggatgaga agtggactca gctgagaatc cgcaaagaga acctaacacg gctgtttgag
     1441 aagatgcagg cttatcagta tgagcaaatc tctgctgacc ctgacaaacc tcttgctgac
     1501 ggcatccggg ctctagatac tactgacatg gagaggctca aagatgttca gtcaatggat
     1561 gaactgaaag acgtctacaa ccatttctta ctttactacg ggcgtgacat ccccaagatg
     1621 cagaatgctg ccaaggctag ccggaagaag ctgaaacgca taaaggagga tggcgatgaa
     1681 gaaggtgaag gtgaggaggc tgaagatgag gaacagaggg gaccagagct caagcaagcc
     1741 tcccgccgag acatgtatac catctgccag agtgccgggc tagatggcct ggccaaaaag
     1801 tttggcctca cacctgagca gtttggggag aacctccgtg acagctacca gcgccacgag
     1861 acagagcagt tccctgcaga gcctttggag ctggccaaag attacgtgtg cagccagttc
     1921 cctacaccag aagctgtgct tgaaggtgcc cgatacatgg ttgcactaca gattgccagg
     1981 gagccccttg tcagacaggt gctgagacaa acctttcagg agagagccaa gctaaacata
     2041 accccaacca agaaaggtag aaaggatgtg gatgaggccc actacgctta ctcttttaag
     2101 tacttaaaga acaagcctgt taaagagctg agagacgacc agttcctcaa gataggcctg
     2161 gctgaggatg aagggctgct caccattgac atcagcatag atatgaaggg agtggaaggg
     2221 tatggtaatg accagacata ttttgaggag atcaagcagt tttactaccg ggatgagttc
     2281 agccaccaag tacaggaatg gaaccggcag cgcactatgg ccattgagcg agctctgcag
     2341 cagttcctct acgtgcaaat ggccaaagaa cttaagaaca agctgctagc tgaggccagg
     2401 gagagtgttg tgaaggcctg tagccgaaag ctctacaact ggttgagagt ggcaccctac
     2461 cgtccagatc agcaggtaga ggaggacgac gactttatgg atgagaacca ggggaagggc
     2521 atccgagtcc taggcattgc tttctcctct gccagagatc accctgtgtt ctgtgcccta
     2581 gtcaatggtg aaggagaagt gactgatttc ctccgcctgc cccattttac caagcggcga
     2641 actgcatgga gagaagagga gcgggaaaag aaggctcaag atattgaaac cctaaagaag
     2701 tttcttgtga ataagaagcc tcatgtggtc actatcgcag gagagaacag ggatgcccag
     2761 atgctgactg aggatgtgaa gcggatagtg catgagctgg accaaggcca acagctgtct
     2821 tctattgggg tggagctggt tgacaatgag ctggccattc tgtacatgaa cagcaagaaa
     2881 tcagaggcag agttccggga ttatccacca gttttgagac aagctgtctc tctagcccgg
     2941 cgtatccaag accctctgat agaatttgcc caggtgtgca gctcagatga agacatcctg
     3001 tgtctcaagt ttcatccctt gcaggagcat gttgtgaaag aggagctgct taacgccttg
     3061 tactgtgaat tcatcaaccg ggtcaatgag gtcggggtgg atgtcaaccg tgccattgcc
     3121 catccttaca gccaggcctt gatccagtat gtctgtggcc tgggaccccg aaaagggacc
     3181 cacctgctga agattttgaa acagaacaac actcgactcg agagccggac tcagctggtc
     3241 accatgtgtc atatgggtcc caaagtcttc atgaattgtg ctggcttcct caagatcgac
     3301 actgcttctc tgggggacag cactgactca tacattgaag ttcttgatgg ctctcgagtc
     3361 caccctgaaa cgtacgagtg ggccaggaag atggcagtgg atgccttaga atacgatgag
     3421 tctgcagaag atgccaatcc tgctggagcc cttgaggaaa tcttggaaaa cccagagcgg
     3481 ctgaaggatt tagatcttga tgcctttgca gaagaactag agagacaggg ctatggtgac
     3541 aagcacatca cactgtatga catccgagca gagctcagtt gtaggtataa ggacctccgg
     3601 acagcctacc gctctcctaa cacagaggag atcttcaata tgttaaccaa agagacgcca
     3661 gagaccttct acattggaaa gcttatcatc tgcaatgtta ccggcattgc tcacaggcgc
     3721 ccacagggtg agagctatga ccaggccatc cgaaatgatg agacagggct gtggcagtgc
     3781 cccttctgtc aacaagacaa cttccctgag ctaagcgagg tctggaacca ttttgacagt
     3841 ggatcatgcc ctggtcaggc cattggtgtg aaaacacggc tagacaatgg cgtcaccggc
     3901 ttcatcccta ccaaattcct cagtgacaag gtggtgaaga ggccagagga gcgagtgaag
     3961 gtggggatga ctgttcactg ccggatcatg aagatcgata ttgaaaagtt cagtgcagac
     4021 ctgacctgcc ggacctcaga cctcatggac aggaacaatg agtggaaact gcccaaggac
     4081 acctactatg actttgatgc ggaagctgca gaccacaagc aggaagagga tatgaaacga
     4141 aagcagcagc ggaccacata catcaagcga gtgattgcac acccgtcctt ccataacata
     4201 aatttcaagc aagcagaaaa gatgatggag accatggacc aaggggatgt tatcattcgg
     4261 cccagcagta aaggtgaaaa ccatctgacg gtgacctgga aagtcagtgc tggcatctac
     4321 cagcacgtgg acgtgcggga agagggcaag gagaacgcct tcagcctggg agccactctt
     4381 tggatcaaca gtgaggaatt tgaagacttg gatgagattg ttgcccgcta tgtccagccc
     4441 atggcttcct ttgctcgaga ccttctgaac cacaaatatt accaggactg tagtggtggg
     4501 gaccgaaaga aattagagga gctgctcatc aaaactaaga aggagaagcc caccttcatc
     4561 ccttacttca tctgtgcctg caaggagctg cccggcaagt tcctcctggg ataccagccc
     4621 cggggtaaac ccaggataga atatgtaaca gtgactcctg aaggattccg gtaccggggc
     4681 cagattttcc caactgtgaa tggactcttc aggtggttta aggatcacta tcaggatcct
     4741 gtaccaggca tcactcccag tagcagtaac agaacacgga cccctgcttc tatcaatgct
     4801 accccagcca acatcaatct tgcagatctc acacgggctg tgaatgcctt gcctcagaac
     4861 atgacttcac agatgttcag tgccattgct gctgtgacag gccaggggca gaaccccaat
     4921 gctaccccag cccagtgggc atccagccag tatggctacg gtggcagcgg aggaggcagc
     4981 agcgcctacc atgtgttccc aacaccagcc cagcagccag tggccacacc actaatgacc
     5041 ccaagctact cctatactac cccgagccag cccattacca ccccacaata ccaccagctc
     5101 caggccagca ccaccccaca gtctacacag gcccagcccc agccttcctc cagctcccga
     5161 caacggcaac agcagccaaa gtccaacagc catgcagcta tcgactgggg caagatggcc
     5221 gagcagtggc tacaggaaaa ggaggcagaa cgacggaaac agaaacagcg gctgacccca
     5281 cgaccctctc ccagccccat gatcgagagc acccccatgt ccattgctgg cgatgcgacc
     5341 ccactcctgg acgagatgga tcggtagggg gcctgttcct cggactctgg ttacctctga
     5401 agctcccaag aggcctggcc acttatggcc tcactccctg cccctctttt ttttttgtcc
     5461 ataaagtggc gtgaaatgac gttcttttta gtggtcagcc tggctggatg gtggccttgt
     5521 gagctggtgt gcaccgagca gcagctgttc cactccgggc ttgtgctaac cacctgttct
     5581 ggggccaggc tgggagagca gtatggcagg gaggagagca aaggtggagc agtctgtaat
     5641 gtctctggaa gccctcacct gagacaggcc ctcatgaggc atgcagctca attgtctatg
     5701 tccccagcct gtgtggggac accgatgcta tttattcagt ttggggcagg agggaaagta
     5761 gctctgatcc tgatggcaag accttggctg tcaaagcagg actgtgaggg ccatgtggag
     5821 cagtgctgag ctgccagccc ctgcctgcct gcctgcctgc cttccctcat cacctaacct
     5881 cacctgcttc tcgcctgtca tttgaataaa cagtgtttgt acagagcgct tgccgaggcc
     5941 tccagctccc tcgctctgta gggctgcttc agcagtttga agctccaaaa acttcctctc
     6001 ataatctacc agagaatcca ggattcacat tgcctggggt tacctcctac ctgctctgag
     6061 ccctgtgacc ctgtgtggac ttcttccatc tgttgtttgc cgtgttgaag tggagtctct
     6121 aacccagact ggccttggcc ttacagcagc cctgcctcag cctcctgaag gctggaatta
     6181 cataaatgat acacgtgcac t
//
