LOCUS       NM_024451               4133 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus Sad1 and UNC84 domain containing 1 (Sun1), transcript
            variant 1, mRNA.
ACCESSION   NM_024451
VERSION     NM_024451.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4133)
  AUTHORS   Zhang,J., Ruiz,M., Bergh,P.O., Henricsson,M., Stojanovic,N.,
            Devkota,R., Henn,M., Bohlooly-Y,M., Hernandez-Hernandez,A.,
            Alsheimer,M., Boren,J., Pilon,M. and Shibuya,H.
  TITLE     Regulation of meiotic telomere dynamics through membrane fluidity
            promoted by AdipoR2-ELOVL2
  JOURNAL   Nat Commun 15 (1), 2315 (2024)
   PUBMED   38485951
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4133)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 4133)
  AUTHORS   Jiao,S., Li,C., Guo,F., Zhang,J., Zhang,H., Cao,Z., Wang,W., Bu,W.,
            Lin,M., Lu,J. and Zhou,Z.
  TITLE     SUN1/2 controls macrophage polarization via modulating nuclear size
            and stiffness
  JOURNAL   Nat Commun 14 (1), 6416 (2023)
   PUBMED   37828059
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4133)
  AUTHORS   Ross,J.A., Arcos-Villacis,N., Battey,E., Boogerd,C., Orellana,C.A.,
            Marhuenda,E., Swiatlowska,P., Hodzic,D., Prin,F., Mohun,T.,
            Catibog,N., Tapia,O., Gerace,L., Iskratsch,T., Shah,A.M. and
            Stroud,M.J.
  TITLE     Lem2 is essential for cardiac development by maintaining nuclear
            integrity
  JOURNAL   Cardiovasc Res 119 (11), 2074-2088 (2023)
   PUBMED   37067297
REFERENCE   5  (bases 1 to 4133)
  AUTHORS   Buglak,D.B., Bougaran,P., Kulikauskas,M.R., Liu,Z.,
            Monaghan-Benson,E., Gold,A.L., Marvin,A.P., Burciu,A., Tanke,N.T.,
            Oatley,M., Ricketts,S.N., Kinghorn,K., Johnson,B.N., Shiau,C.E.,
            Rogers,S., Guilluy,C. and Bautch,V.L.
  TITLE     Nuclear SUN1 stabilizes endothelial cell junctions via microtubules
            to regulate blood vessel formation
  JOURNAL   Elife 12, e83652 (2023)
   PUBMED   36989130
  REMARK    GeneRIF: Nuclear SUN1 stabilizes endothelial cell junctions via
            microtubules to regulate blood vessel formation.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4133)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   7  (bases 1 to 4133)
  AUTHORS   VanBuren,V., Piao,Y., Dudekula,D.B., Qian,Y., Carter,M.G.,
            Martin,P.R., Stagg,C.A., Bassey,U.C., Aiba,K., Hamatani,T.,
            Kargul,G.J., Luo,A.G., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Assembly, verification, and initial annotation of the NIA mouse
            7.4K cDNA clone set
  JOURNAL   Genome Res 12 (12), 1999-2003 (2002)
   PUBMED   12466305
REFERENCE   8  (bases 1 to 4133)
  AUTHORS   Bray,J.D., Chennathukuzhi,V.M. and Hecht,N.B.
  TITLE     Identification and characterization of cDNAs encoding four novel
            proteins that interact with translin associated factor-X
  JOURNAL   Genomics 79 (6), 799-808 (2002)
   PUBMED   12036294
REFERENCE   9  (bases 1 to 4133)
  AUTHORS   Dreger,M., Bengtsson,L., Schoneberg,T., Otto,H. and Hucho,F.
  TITLE     Nuclear envelope proteomics: novel integral membrane proteins of
            the inner nuclear membrane
  JOURNAL   Proc Natl Acad Sci U S A 98 (21), 11943-11948 (2001)
   PUBMED   11593002
REFERENCE   10 (bases 1 to 4133)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY036585.1, AK160281.1 and AK167686.1.
            
            On Jan 6, 2012 this sequence version replaced NM_024451.1.
            
            Transcript Variant: This variant (1) is the longest transcript and
            encodes the longest isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK160281.1, AK167686.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-43                BY036585.1         1-43
            44-898              AK160281.1         2-856
            899-1596            AK167686.1         871-1568
            1597-4133           AK160281.1         1555-4091
FEATURES             Location/Qualifiers
     source          1..4133
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 78.12 cM"
     gene            1..4133
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /note="Sad1 and UNC84 domain containing 1"
                     /db_xref="GeneID:77053"
                     /db_xref="MGI:MGI:1924303"
     exon            1..63
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            64..160
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     CDS             84..2825
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein unc-84 homolog A; SUN domain-containing protein 1;
                     sad1/unc-84 protein-like 1"
                     /codon_start=1
                     /product="SUN domain-containing protein 1 isoform 1"
                     /protein_id="NP_077771.1"
                     /db_xref="CCDS:CCDS19804.1"
                     /db_xref="GeneID:77053"
                     /db_xref="MGI:MGI:1924303"
                     /translation="MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHKLEP
                     VFDSPRMSRRSLRLVTTASYSSGDSQAIDSHISTSRATPAKGRETRTVKQRRSASKPA
                     FSINHLSGKGLSSSTSHDSSCSLRSATVLRHPVLDESLIREQTKVDHFWGLDDDGDLK
                     GGNKAATQGNGELAAEVASSNGYTCRDCRMLSARTDALTAHSAIHGTTSRVYSRDRTL
                     KPRGVSFYLDRTLWLAKSTSSSFASFIVQLFQVVLMKLNFETYKLKGYESRAYESQSY
                     ETKSHESEAHLGHCGRMTAGELSRVDGESLCDDCKGKKHLEIHTATHSQLPQPHRVAG
                     AMGRLCIYTGDLLVQALRRTRAAGWSVAEAVWSVLWLAVSAPGKAASGTFWWLGSGWY
                     QFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGVSLWGQGNFFSLLPVLNWTA
                     MQPTQRVDDSKGMHRPGPLPPSPPPKVDHKASQWPQESDMGQKVASLSAQCHNHDERL
                     AELTVLLQKLQIRVDQVDDGREGLSLWVKNVVGQHLQEMGTIEPPDAKTDFMTFHHDH
                     EVRLSNLEDVLRKLTEKSEAIQKELEETKLKAGSRDEEQPLLDRVQHLELELNLLKSQ
                     LSDWQHLKTSCEQAGARIQETVQLMFSEDQQGGSLEWLLEKLSSRFVSKDELQVLLHD
                     LELKLLQNITHHITVTGQAPTSEAIVSAVNQAGISGITEAQAHIIVNNALKLYSQDKT
                     GMVDFALESGGGSILSTRCSETYETKTALLSLFGVPLWYFSQSPRVVIQPDIYPGNCW
                     AFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPKDFAVYGLETEYQEEGQ
                     PLGRFTYDQEGDSLQMFHTLERPDQAFQIVELRVLSNWGHPEYTCLYRFRVHGEPIQ"
     exon            161..352
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            353..537
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            538..564
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            565..744
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            745..936
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            937..1002
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1113
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1212
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..1306
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1307..1365
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..1511
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1512..1751
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1752..1838
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1839..1882
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1883..1994
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            1995..2249
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            2250..2334
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            2335..2450
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            2451..2618
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            2619..2711
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     exon            2712..4133
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4064..4069
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /note="hexamer: AATAAA"
     polyA_site      4089
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /note="major polyA site"
     regulatory      4111..4116
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
                     /note="hexamer: AATAAA"
     polyA_site      4133
                     /gene="Sun1"
                     /gene_synonym="4632417G13Rik; 5730434D03Rik; mKIAA0810;
                     Unc84a"
ORIGIN      
        1 ggggagtctt cggtcccggg cctgggcggt gcggacgagg cctgaggcgg cggcgcgagg
       61 cagcatggtc tgagacggtg aacatggact tttctcggct gcacacgtac accccacccc
      121 agtgtgtgcc ggagaacact ggctacactt acgcactcag ttctagttac tcgtcggatg
      181 ctctggattt tgaaactgag cacaagttgg aacctgtatt tgactctcca aggatgtccc
      241 gccgcagctt gcgtctggtc acaacagctt cgtacagcag tggggacagc caggctattg
      301 attcgcacat tagcaccagc agggccaccc ccgccaaggg gagagaaacc aggacagtca
      361 aacagagaag aagtgcaagc aagccagctt ttagtatcaa ccacctgtca gggaagggct
      421 tgtcctcgag cacaagccat gacagctctt gcagcctgcg gagtgccacg gtgctgcggc
      481 accctgtgct agatgagtcc ctgattcgtg agcagaccaa agtggaccac ttctggggtc
      541 tcgatgatga tggtgacctt aaaggtggaa ataaagctgc cactcaggga aatggtgaac
      601 tggcagcaga ggtggcgagc agcaatggat acacttgccg tgactgcagg atgctctcag
      661 cgcgcactga cgcactcaca gcccactctg ccatccacgg gaccacctcc agggtgtact
      721 ccagagacag gactctcaaa ccacgcggag tgtcctttta cctggatagg actctgtggc
      781 tggccaagtc cacctcctca tcctttgcat catttatagt tcaacttttc caagtggttt
      841 taatgaagct caattttgaa acttacaaat tgaaaggcta tgaatccaga gcttatgaat
      901 cacagagcta tgagacaaag agccatgagt cagaagccca tctcggtcac tgtgggagga
      961 tgactgccgg agaactttcc agagtggacg gggagtccct gtgcgatgac tgtaagggga
     1021 agaagcacct tgagatacac acagccaccc actcgcaact gccccagcca cacagggtgg
     1081 ccggggccat ggggcgcctc tgcatctata caggtgacct cttggttcaa gcactgcgaa
     1141 ggactagagc tgccgggtgg tctgtggccg aggccgtgtg gtcggtgctc tggctggctg
     1201 tctctgctcc agggaaggca gcctcgggaa ccttctggtg gctagggagc ggctggtacc
     1261 aatttgttac tttgatttct tggctgaatg tctttcttct taccaggtgc cttcgaaata
     1321 tttgcaaggt ttttgtcttg ctcctcccac tcctactttt actaggtgct ggtgtctccc
     1381 tgtggggcca gggaaacttc ttctcactcc taccagtgct gaactggacg gccatgcagc
     1441 caacacagag ggtggacgat tccaagggca tgcatagacc tggccctctt cccccgagcc
     1501 cacctccaaa ggttgatcac aaggcttccc agtggcctca ggagagtgac atggggcaga
     1561 aggtagcttc tttgagtgcg cagtgccaca accatgatga gagacttgca gagctgacag
     1621 tcctgcttca gaaactacag atacgggtag accaagtgga tgacggcagg gaagggctgt
     1681 cactgtgggt caagaatgtg gttggacagc acctgcagga gatgggcacc atagaaccac
     1741 ctgatgctaa gactgacttc atgactttcc accatgacca tgaagtgcgt ctctccaact
     1801 tggaagatgt tcttagaaaa ctgacagaaa aatctgaggc tatccagaag gagctggaag
     1861 aaaccaagct gaaagcaggc agcagggatg aagagcagcc cctccttgac cgtgtgcagc
     1921 acctagaact ggaactgaac ctgttgaagt cacagctgtc agactggcag catctgaaga
     1981 ccagctgtga gcaggctggg gcccgcatcc aggagactgt gcagctcatg ttctctgagg
     2041 atcagcaggg cggttccctc gagtggctat tagagaagct ttcttctcgg ttcgtgagca
     2101 aggatgagct gcaggtgctc ttacatgacc ttgagctgaa actgctgcag aatatcacac
     2161 accacatcac cgtgacagga caggccccga catccgaggc tattgtgtct gccgtgaatc
     2221 aggcagggat ttcaggaatc acagaagcgc aagcacatat cattgtgaac aatgctctga
     2281 agctgtactc ccaagacaag acggggatgg tggactttgc tctggagtct ggaggtggca
     2341 gcatcctaag cactcggtgc tctgagacct atgagaccaa gacggcactg ctgagcctgt
     2401 ttggggtccc actgtggtac ttctcacagt cacctcgagt ggtgatccag cccgacatct
     2461 acccagggaa ttgctgggcg ttcaaaggtt cccaggggta cctggtggtg cggttgtcca
     2521 tgaagatcta cccaaccaca ttcaccatgg aacacattcc aaagacacta tcacccactg
     2581 gtaacatctc cagtgccccc aaagactttg cagtctatgg actggaaacg gagtatcaag
     2641 aagaggggca gcctctggga cggttcacct atgaccagga aggagactca ctccagatgt
     2701 tccacacact ggaaagacct gaccaagcct tccagatagt agagctccgg gtcctgtcca
     2761 actggggcca ccctgagtac acttgcctct accggttccg agtccacgga gagcccatcc
     2821 agtagagcac tccagccatg tacatgtctg tatataccaa gacgccataa cactggaact
     2881 cattgagaaa gagagcacgt gagcatagga acttgtcagc cacccttcaa taaatgtgct
     2941 gtggtcctga ggacgtgctg agtcctctga ggctgtgcgt gtgttctcaa agcccaaaag
     3001 ccggggaggc ttttttaatt catttgaatg tatgattctc ggacactcct tttgacttag
     3061 ggatttgctt gaatgcataa agtcaagaag cagataggct ggcaggtttc caggctcctg
     3121 acataaaggc tgagagctct gcattggcca tcctctggat gtcaagaagg caaagtccca
     3181 tctgctaaac ccacgtttct ttcagggaaa actgttgctc tgtcttcagt ctgacccctt
     3241 ccaggttccc tggtggggag aggctatgtc atagactgtc tgctttgagc tgggactcct
     3301 ctgattcccc aggggagtag atcgggcttt gcagaagagc agtggggtgt gcacaccatg
     3361 aatggtgctc ttgggtctca gccaggccgt tcctggcaga tcacagaatg gacaggaacc
     3421 ttgagaaggg atgctctgct gtccttgagc tatgagtctc tgctgaaggg ggaacactaa
     3481 ggtggtgcta gtggctgcca ctcttggtct ttatcacagc agcattctgt gctgcccttg
     3541 ggtttgcctc tacaccatta tcagcccttc tcactgattc aaatttgggt atatttaata
     3601 tttagacttt tgtgagtaga ctttataact gatacatcat ctggacactt aaaagtgttt
     3661 agatgtctta cctaaagaat tgttaagttt cattggttag acagccttgg cagaatacaa
     3721 agctcacctg ctggggctca gagttctggg atttctcgca tgttgcaagc agcccttaag
     3781 acagtggccc aaagcacatc ccactccata gggttagagc cactgcctgt gtggccaggt
     3841 tgtgtgggat gcacacattt tgcatactca aggttacatg cagaagtcag aatttcctat
     3901 attaaactaa attggggaat tgggggtgga gatatttcaa atatttattt ttaaagatgc
     3961 aagataggac tttgtgcaat gtatttttgt aaatgctttt caaaacactt gtctttggta
     4021 gtgcttctac tgccactaaa ttaagatgct attgagatgt ttaaataaaa gagttaattt
     4081 ttaaaagtgc atgtgcgatt tcaagtgatt aataaaagtg tgtatttctt ttc
//
