LOCUS       NM_026445               1644 bp    mRNA    linear   ROD 14-FEB-2025
DEFINITION  Mus musculus sulfatase modifying factor 2 (Sumf2), transcript
            variant 1, mRNA.
ACCESSION   NM_026445 XM_355742
VERSION     NM_026445.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1644)
  AUTHORS   Uijtdewilligen,P.J.E., Versteeg,E.M., van de Westerlo,E.M.A., van
            der Vlag,J., Daamen,W.F. and van Kuppevelt,T.H.
  TITLE     Dynamic Expression of Genes Involved in
            Proteoglycan/Glycosaminoglycan Metabolism during Skin Development
  JOURNAL   Biomed Res Int 2018, 9873471 (2018)
   PUBMED   30228991
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1644)
  AUTHORS   Zito,E., Fraldi,A., Pepe,S., Annunziata,I., Kobinger,G., Di
            Natale,P., Ballabio,A. and Cosma,M.P.
  TITLE     Sulphatase activities are regulated by the interaction of
            sulphatase-modifying factor 1 with SUMF2
  JOURNAL   EMBO Rep 6 (7), 655-660 (2005)
   PUBMED   15962010
  REMARK    Erratum:[EMBO Rep. 2016 Dec;17(12):1901. doi:
            10.15252/embr.201570010.. PMID: 27909074]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC242408.2.
            
            On Mar 9, 2023 this sequence version replaced NM_026445.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK157784.1, AK138300.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-97                AC242408.2         40243-40339         c
            98-254              AC242408.2         37272-37428         c
            255-366             AC242408.2         34344-34455         c
            367-411             AC242408.2         33262-33306         c
            412-562             AC242408.2         32491-32641         c
            563-618             AC242408.2         29034-29089         c
            619-703             AC242408.2         27408-27492         c
            704-848             AC242408.2         27115-27259         c
            849-1644            AC242408.2         23895-24690         c
FEATURES             Location/Qualifiers
     source          1..1644
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 68.26 cM"
     gene            1..1644
                     /gene="Sumf2"
                     /gene_synonym="2610040F05Rik"
                     /note="sulfatase modifying factor 2"
                     /db_xref="GeneID:67902"
                     /db_xref="MGI:MGI:1915152"
     exon            1..97
                     /gene="Sumf2"
                     /gene_synonym="2610040F05Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             7..933
                     /gene="Sumf2"
                     /gene_synonym="2610040F05Rik"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; C-alpha-formylglycine-generating enzyme 2;
                     inactive C-alpha-formylglycine-generating enzyme 2"
                     /codon_start=1
                     /product="inactive C-alpha-formylglycine-generating enzyme
                     2 isoform 1 precursor"
                     /protein_id="NP_080721.1"
                     /db_xref="CCDS:CCDS19700.1"
                     /db_xref="GeneID:67902"
                     /db_xref="MGI:MGI:1915152"
                     /translation="MRSEFWFPSMGSLLPPVLLLWLLSCPRLQLGHAQDPAMVHLPGG
                     RFLMGTDAPDGRDGEGPAREVTVKPFAIDIFPVTNKDFREFVREKKYQTEAEAFGWSF
                     VFEDFVSPELRKQENLMPAVHWWQPVPKAFWRQPAGPGSGIREKLELPVVHVSWNDAG
                     AYCAWRGRRLPTEEEWEFAARGGLKGQVYPWGNRFQPNRTNLWQGKFPKGDKAEDGFH
                     GLSPVNAFPPQNNYGLYDLMGNVWEWTASTYQPAGQDMRVLRGASWIDTADGSANHRA
                     RVTTRMGNTPDSASDNLGFRCASSAGRPKEDL"
     exon            98..254
                     /gene="Sumf2"
                     /gene_synonym="2610040F05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            255..366
                     /gene="Sumf2"
                     /gene_synonym="2610040F05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            367..411
                     /gene="Sumf2"
                     /gene_synonym="2610040F05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            412..562
                     /gene="Sumf2"
                     /gene_synonym="2610040F05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            563..618
                     /gene="Sumf2"
                     /gene_synonym="2610040F05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            619..703
                     /gene="Sumf2"
                     /gene_synonym="2610040F05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            704..848
                     /gene="Sumf2"
                     /gene_synonym="2610040F05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            849..1644
                     /gene="Sumf2"
                     /gene_synonym="2610040F05Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1452..1457
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sumf2"
                     /gene_synonym="2610040F05Rik"
                     /note="hexamer: AGTAAA"
     polyA_site      1478
                     /gene="Sumf2"
                     /gene_synonym="2610040F05Rik"
     regulatory      1622..1627
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sumf2"
                     /gene_synonym="2610040F05Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1644
                     /gene="Sumf2"
                     /gene_synonym="2610040F05Rik"
                     /note="major polyA site"
ORIGIN      
        1 agacgcatgc gctctgagtt ctggttcccc agcatgggtt ccttgctccc tccggtgttg
       61 ctgctgtggc tcctgtcctg ccccaggctt cagctaggac atgcccagga tcctgccatg
      121 gtgcatctgc caggtggccg gtttctgatg gggacagacg ctccagatgg cagagacggt
      181 gaagggcctg cccgggaagt gacagtaaaa ccctttgcca tcgacatatt tccagtcacc
      241 aataaagact tcagggagtt tgtcagggag aagaagtacc agactgaagc cgaggcattc
      301 gggtggagct tcgtctttga ggattttgtc tcccctgagc tcagaaagca agaaaatctg
      361 atgccggctg ttcactggtg gcagccagtg ccaaaggcat tttggaggca gcctgcaggt
      421 cccggctctg gcatccgaga gaaactggag cttcccgtgg tacacgtgag ctggaacgac
      481 gctggtgctt actgcgcatg gcgggggaga cgcttgccca cagaagagga gtgggagttt
      541 gcagcccgag ggggcttgaa gggtcaggtt tatccatggg ggaaccggtt ccagccaaac
      601 cgcaccaact tatggcaggg aaagttcccc aaaggtgaca aagctgaaga tggttttcat
      661 ggactgtcac cagtgaacgc tttcccccca cagaacaact acggactgta tgacctcatg
      721 ggcaatgtgt gggagtggac agcgtccaca taccaacctg ctggccagga catgcgtgtc
      781 ctccgggggg catcatggat cgacaccgca gacggctctg ctaatcacag ggctcgggtc
      841 accaccagga tgggaaacac tccagactca gcctcagaca acctgggctt ccgctgcgcc
      901 tccagtgcag gccgaccgaa ggaggacctg tgagcagcca gaccgagatc tccgaagcac
      961 cctctcagca ctgtacctcc gtgaccatgt tccagaggca gctggctacc aagctcatgc
     1021 gtctgagggt ggccttttga gcccctcccc tctgacagac acaaagaaca ctcggactgc
     1081 aagaagggac tgcagtagcc tggaagatga ggacctggat gaccaaggct gggagctggg
     1141 ctgtctctta agtgcagtat taaggacaaa ggaaccaaac cctccagtgt ccaaaagatg
     1201 acatttttta aactctctcc ctttttgctt tctccctggc tggttcagct ttcacttctg
     1261 ggaaattctg cagaaggaaa atgcttcctt tgtgaggtgt gccaaagcct tgctgccaga
     1321 acctagcctc gctggcctct gaaacgagat actcaatatg tggcaaggct ggtctcgaac
     1381 tctcgatcct cctacctcag cttcctgggt cctgctggga ttacacacca cgcccactat
     1441 ttaaaagccc cagtaaagca aatgatttat gaagtgaaga tgtgcattgt gggagaacca
     1501 aagtcagtgc ccctctagga agacaaatgc cagaaccttc tctgagagtt agctaatcat
     1561 gtagggcctt ctgtgtatcc tgcagacatg tccctgaaga agaactggat cttatgaggt
     1621 caataaatcc tttttttttt ttaa
//
