LOCUS       NM_018751               1566 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus sulfotransferase family, cytosolic, 1C, member 1
            (Sult1c1), mRNA.
ACCESSION   NM_018751
VERSION     NM_018751.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1566)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1566)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1566)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 1566)
  AUTHORS   Runge-Morris,M. and Kocarek,T.A.
  TITLE     Expression of the sulfotransferase 1C family: implications for
            xenobiotic toxicity
  JOURNAL   Drug Metab Rev 45 (4), 450-459 (2013)
   PUBMED   24028175
  REMARK    Review article
REFERENCE   5  (bases 1 to 1566)
  AUTHORS   Blanchard,R.L., Freimuth,R.R., Buck,J., Weinshilboum,R.M. and
            Coughtrie,M.W.
  TITLE     A proposed nomenclature system for the cytosolic sulfotransferase
            (SULT) superfamily
  JOURNAL   Pharmacogenetics 14 (3), 199-211 (2004)
   PUBMED   15167709
  REMARK    Review article
REFERENCE   6  (bases 1 to 1566)
  AUTHORS   Torrey,T., Kim,W., Morse,H.C. 3rd and Kozak,C.A.
  TITLE     Cloning, expression and genetic mapping of the mouse SH3 domain
            protein, SH3D2B
  JOURNAL   Mamm Genome 9 (1), 74-75 (1998)
   PUBMED   9434950
REFERENCE   7  (bases 1 to 1566)
  AUTHORS   Boudjelal,M., Taneja,R., Matsubara,S., Bouillet,P., Dolle,P. and
            Chambon,P.
  TITLE     Overexpression of Stra13, a novel retinoic acid-inducible gene of
            the basic helix-loop-helix family, inhibits mesodermal and promotes
            neuronal differentiation of P19 cells
  JOURNAL   Genes Dev 11 (16), 2052-2065 (1997)
   PUBMED   9284045
REFERENCE   8  (bases 1 to 1566)
  AUTHORS   Her,C., Raftogianis,R. and Weinshilboum,R.M.
  TITLE     Human phenol sulfotransferase STP2 gene: molecular cloning,
            structural characterization, and chromosomal localization
  JOURNAL   Genomics 33 (3), 409-420 (1996)
   PUBMED   8661000
REFERENCE   9  (bases 1 to 1566)
  AUTHORS   Miyawaki,A., Homma,H., Tamura,H., Matsui,M. and Mikoshiba,K.
  TITLE     Zonal distribution of sulfotransferase for phenol in olfactory
            sustentacular cells
  JOURNAL   EMBO J 15 (9), 2050-2055 (1996)
   PUBMED   8641270
REFERENCE   10 (bases 1 to 1566)
  AUTHORS   Khan,A.S., Taylor,B.R., Filie,J.D., Ringer,D.P. and Kozak,C.A.
  TITLE     Rat phenol-preferring sulfotransferase genes (Stp and Stp2):
            localization to mouse chromosomes 7 and 17
  JOURNAL   Genomics 26 (2), 417-419 (1995)
   PUBMED   7601475
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC045149.1.
            
            On Dec 20, 2003 this sequence version replaced NM_018751.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC045149.1, AF033653.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1566
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 28.07 cM"
     gene            1..1566
                     /gene="Sult1c1"
                     /gene_synonym="(PST)G; mOLFST; P-SULT; ST1C1; Stp2;
                     Sult1a2"
                     /note="sulfotransferase family, cytosolic, 1C, member 1"
                     /db_xref="GeneID:20888"
                     /db_xref="MGI:MGI:102928"
     exon            1..117
                     /gene="Sult1c1"
                     /gene_synonym="(PST)G; mOLFST; P-SULT; ST1C1; Stp2;
                     Sult1a2"
                     /inference="alignment:Splign:2.1.0"
     exon            118..313
                     /gene="Sult1c1"
                     /gene_synonym="(PST)G; mOLFST; P-SULT; ST1C1; Stp2;
                     Sult1a2"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..1056
                     /gene="Sult1c1"
                     /gene_synonym="(PST)G; mOLFST; P-SULT; ST1C1; Stp2;
                     Sult1a2"
                     /EC_number="2.8.2.-"
                     /note="sulfotransferase family 1A, phenol-preferring,
                     member 2; phenol sulfotransferase"
                     /codon_start=1
                     /product="sulfotransferase 1C1"
                     /protein_id="NP_061221.2"
                     /db_xref="CCDS:CCDS28884.1"
                     /db_xref="GeneID:20888"
                     /db_xref="MGI:MGI:102928"
                     /translation="MPLEKLKDLHLDEQNMQPETREVNGILMSKMMSENWDKIWNFQA
                     KPDDLLIATYAKAGTTWTQEIVDMIQNDGDVQKCQRANTYDRHPFIEWTLPPPLNSGL
                     DLANKMPSPRTLKTHLPVQMLPPSFWKENSKIIYVARNAKDCLVSYYYFSRMNKMLPD
                     PGTLGEYIETFKAGKVLWGSWYDHVKGWWDVKDKHRILYLFYEDMKEDPKREIKKIVK
                     FLEKDISEEVLNKIIHHTSFDVMKQNPMANYTTLPSSIMDHSISPFMRKGMPGDWKNY
                     FTVAQSEDFDEDYRKKMAGSTITFRTEI"
     exon            314..442
                     /gene="Sult1c1"
                     /gene_synonym="(PST)G; mOLFST; P-SULT; ST1C1; Stp2;
                     Sult1a2"
                     /inference="alignment:Splign:2.1.0"
     exon            443..540
                     /gene="Sult1c1"
                     /gene_synonym="(PST)G; mOLFST; P-SULT; ST1C1; Stp2;
                     Sult1a2"
                     /inference="alignment:Splign:2.1.0"
     exon            541..667
                     /gene="Sult1c1"
                     /gene_synonym="(PST)G; mOLFST; P-SULT; ST1C1; Stp2;
                     Sult1a2"
                     /inference="alignment:Splign:2.1.0"
     exon            668..762
                     /gene="Sult1c1"
                     /gene_synonym="(PST)G; mOLFST; P-SULT; ST1C1; Stp2;
                     Sult1a2"
                     /inference="alignment:Splign:2.1.0"
     exon            763..943
                     /gene="Sult1c1"
                     /gene_synonym="(PST)G; mOLFST; P-SULT; ST1C1; Stp2;
                     Sult1a2"
                     /inference="alignment:Splign:2.1.0"
     exon            944..1513
                     /gene="Sult1c1"
                     /gene_synonym="(PST)G; mOLFST; P-SULT; ST1C1; Stp2;
                     Sult1a2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1266..1271
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sult1c1"
                     /gene_synonym="(PST)G; mOLFST; P-SULT; ST1C1; Stp2;
                     Sult1a2"
                     /note="hexamer: AATAAA"
     polyA_site      1287
                     /gene="Sult1c1"
                     /gene_synonym="(PST)G; mOLFST; P-SULT; ST1C1; Stp2;
                     Sult1a2"
                     /note="major polyA site"
ORIGIN      
        1 cagaactcaa aagctatcct ggaagatccg tctaaagaca gtgaagtcat caacggtcaa
       61 caaacaggga acagggaaca caggccaagg tagagatcgg tcctcacctg acatcctagc
      121 ctgtcaagtc cccattctaa gatgcccttg gaaaaattga aagacctcca cctcgatgaa
      181 cagaacatgc agccagaaac cagggaagtg aatgggattc taatgtccaa gatgatgagt
      241 gaaaactggg acaaaatttg gaacttccaa gcaaagcccg atgatctcct cattgcaacc
      301 tatgcaaagg caggtaccac ctggacacag gaaattgtgg acatgatcca aaatgatggg
      361 gatgttcaaa agtgccagcg ggccaatacc tatgaccgac accctttcat tgagtggact
      421 ttgcctccac ccctcaactc aggtctggat ctggctaaca aaatgccttc acctagaact
      481 ctgaagactc atctgcctgt tcaaatgctt ccaccttcct tttggaaaga aaactcaaag
      541 attatctatg tggccagaaa tgccaaggac tgcctggtat cttactacta tttctcaaga
      601 atgaataaaa tgctgcctga ccctggtacc ctgggagaat acattgaaac cttcaaagct
      661 ggaaaagtgc tgtggggctc ctggtatgac catgtaaagg gatggtggga tgtgaaagac
      721 aaacaccgta ttctgtacct cttctatgaa gacatgaaag aggaccctaa aagggaaatt
      781 aagaagatag taaaattcct ggaaaaagac atttcagagg aagttctaaa taaaatcatc
      841 catcacacct cctttgatgt aatgaagcag aacccaatgg ccaactatac cactctaccc
      901 tccagtatca tggaccactc tatatctcct ttcatgagaa aagggatgcc tggagactgg
      961 aagaactact ttaccgtggc acaaagtgag gattttgatg aagactaccg gaagaagatg
     1021 gcagggagca ctattacctt ccgcacagag atctgagagc agtagggtag agggaatccc
     1081 tagatgtcct gactgtatgc tttagctatt tgagcctcca ttcctaagcg gttgcacggt
     1141 tctatgtgtc ctatgattct atttcatcaa aaggtaatca gaccttctac agaaattttt
     1201 ggttacacta tgtgaatatt attgatacct accacacaat catgtacttc actacacttg
     1261 ggcaaaataa acggaatgcc ttcactagcc tccagttgtt ttgtctcaca gcaaagctca
     1321 tgaatagaaa gacacatagg aaaacaggat ttgacataag aaagtaaata tgaaaagcaa
     1381 aaggaatgag aactgagcac tggtcataaa ccgaagacta gctaattttc ttaacaatta
     1441 tcttcatctg ttctacggca ctttaacaaa acacctaatt tgtttataaa gaataaaaac
     1501 cacttcttat gtaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1561 aaaaaa
//
